Immunocytochemical localization of lipophorins in the flight muscles of the migratory locust (Locusta migratoria) at rest and during flight.

Abstract:

:Locust lipoproteins (lipophorins) were localized by indirect immunofluorescence- and immunogold labelling in cryosections of dorsolongitudinal flight muscles. Immunolabelling was performed with monoclonal antibodies against apolipoproteins epitopes that are exposed at the surfaces of the lipophorin particles. Both at rest and during flight, lipophorins were located only in the wider spaces of the extracellular matrix, in the basement membranes of the individual muscle fibers and in the extracellular spaces that surround interfibrillar tracheoles. No internalization of lipophorins by the flight muscle cells was observed. Our results indicate that the unloading of lipophorins at the flight muscles is an extracellular event. Similarities with the vertebrate system of chylomicron and very-low-density lipoprotein degradation are discussed.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Van Antwerpen R,Linnemans WA,Van der Horst DJ,Beenakkers AM

doi

10.1007/BF00216654

subject

Has Abstract

pub_date

1988-06-01 00:00:00

pages

661-8

issue

3

eissn

0302-766X

issn

1432-0878

journal_volume

252

pub_type

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