Abstract：
:Ependymal cells and their junctional complexes in the area postrema of the rat were studied in detail by tracer experiments using horseradish peroxidase (HRP) and colloidal lanthanum and by freeze-etch techniques, in addition to routine electron microscopy. The ependyma of the area postrema is characterized as flattened cells possessing very few cilia, a moderate amount of microvilli, a well-developed Golgi apparatus and rough endoplasmic reticulum. Numerous vesicles or tubular formations with internal dense content were found to accumulate in the basal processes of ependymal cells; the basal process makes contact with the perivascular basal lamina. It is suggested that the dense material in the tubulovesicular formations is synthesized within the ependymal cell and discharged into the perivascular space. The apical junctions between adjacent ependymal cells display very close apposition, with a gap of 2--3 nm, but no fusion of adjacent plasma membranes; they thus represent a transitional form between the zonulae adhaerentes present in the ordinary mural ependyma and the zonulae occludentes in the choroidal epithelium. A direct intercommunication between the ventricular cerebrospinal fluid (CSF) and the blood vascular system indicates that a region exists lacking a blood-ventricular CSF barrier.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Gotow T,Hashimoto PHdoi
10.1007/BF00235058subject
Has Abstractpub_date
1979-09-03 00:00:00pages
207-25issue
2eissn
0302-766Xissn
1432-0878journal_volume
201pub_type
杂志文章abstract：:Two dozen hybrid clones were produced by fusion of diploid embryonic stem (ES) cells positive for green fluorescent protein (GFP) with tetraploid fibroblasts derived from DD/c and C57BL-I(I)1RK mice. Cytogenetic analysis demonstrated that most cells from these hybrid clones contained near-hexaploid chromosome sets. Ad...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-0987-3
更新日期：2010-06-01 00:00:00
abstract：:Endothelial repair to reestablish structural integrity following wounding is a complex process. Since the actin cytoskeleton undergoes specific changes in distribution as quiescent endothelial cells switch to activated migrating cells over a 6-h period following wounding (Lee et al. 1996), we studied tyrosine phosphor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051370
更新日期：1999-09-01 00:00:00
abstract：:Immunoreactivity for calcitonin gene-related peptide is demonstrated for the first time in neuroepithelial bodies in the lung of newborn cats after Bouin fixation and embedding in paraffin. The intense staining clearly identifies these bodies at the level of bronchioli and alveoli. Occasionally, single neuroepithelial...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215517
更新日期：1987-08-01 00:00:00
abstract：:We chose synaptic terminals of rat rod bipolar cells as a model system to study activity-related changes in the overall morphology and the fine structure of synaptic sites. Using confocal laser scanning microscopy in conjunction with three-dimensional reconstruction and electron microscopy, we examined the effect of l...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051174
更新日期：1998-11-01 00:00:00
abstract：:The distribution and structure of the ureteric nerves in a small series of mammals was compared with that previously demonstrated in the rat. There was marked interspecies variation in the extent to which the nerves penetrated the wall of the ureter and in the degree of development of the deep submucous plexus. In ani...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00225768
更新日期：1975-07-23 00:00:00
abstract：:CD4+CD25+(high) regulatory T cells (Tregs) play a pivotal role in the control of the immune response. A growing body of evidence suggests the reduced function of these cells in autoimmune diseases, including type 1 diabetes (T1D). Restoration of their function can potentially delay further disease development. In the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0900-0
更新日期：2010-03-01 00:00:00
abstract：:By a regular immunoperoxidase method, alpha-1-proteinase inhibitor (Api) was demonstrated in pancreatic islets in individuals with and without genetic deficiency of Api. Subsequently a double immunoperoxidase method, with two different chromogens (diaminobenzidine-brown and 4-chloro-1-naphthol-blue), was applied on th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218078
更新日期：1986-01-01 00:00:00
abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with highly potent neurotrophic and neuroprotective effects. PACAP and its receptors occur in the retina and PACAP has been applied in animal models of metabolic retinal disorders to reduce structural and functional damage. Furthermore, PACAP...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1349-0
更新日期：2012-04-01 00:00:00
abstract：:Sox2-expressing stem/progenitor cells in the anterior lobe of the pituitary gland form two types of micro-environments (niches): the marginal cell layer and dense cell clusters in the parenchyma. In relation to the mechanism of regulation of niches, juxtacrine signaling via ephrin and its receptor Eph is known to play...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2646-4
更新日期：2017-10-01 00:00:00
abstract：:Osteoclasts are highly polarized cells from both morphological and functional points of view. Using quick-freeze, rotary-replication methods combined with cell-shearing, we clarified the variability of cytoplasmic surface of the polarized membranes of osteoclasts seeded on apatite. As to the organization of actin fila...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-2085-4
更新日期：2015-05-01 00:00:00
abstract：:Trichoplax, a member of the phylum Placozoa, is a tiny ciliated marine animal that glides on surfaces feeding on algae and cyanobacteria. It stands out from other animals in that it lacks an internal digestive system and, instead, digests food trapped under its lower surface. Here we review recent work on the phenotyp...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-019-03057-z
更新日期：2019-09-01 00:00:00
abstract：:The distribution of radioactivity in the rat hypothalamus after intraventricular injection of tritiated luteinizing hormone-releasing hormone (LH-RH) was studied by autoradiography and compared with that expected from Fick's second law which defines the character of ordinary diffusion. The results suggest that LH-RH p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215317
更新日期：1976-05-13 00:00:00
abstract：:An ultrastructural study of the rostral pars distalis of the pituitary of Aphanius dispar specimens taken from freshwater or hypersaline marshes revealed significant structural differences which indicate higher activity of the prolactin cells in the hypotonic medium. Prolactin cells from freshwater specimens had large...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221103
更新日期：1977-04-20 00:00:00
abstract：:Calcitonin gene-related peptide-immunoreactive cells were identified within the epithelium of distal conducting airways in the human fetus and infant. Several peptides and amines, including calcitonin, have been identified previously within a specific population of airway epithelial cells. These cells, referred to as ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218949
更新日期：1987-12-01 00:00:00
abstract：:Elastic cartilage-derived cells cultured two-dimensionally with FGF2 and corticosteroid produce gel-type masses that become mature cartilage when injected into a subcutaneous pocket. This unique method has previously been clinically applied for treatments of nasal augmentation. However, the components of the gel-type ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0438-y
更新日期：2007-09-01 00:00:00
abstract：:A monoclonal antibody (Mab) developed against a partially purified bursal protein extract was found to bind specifically to a single cell type in the cortico-medullary border region of the chicken bursa of Fabricius. These cells were microscopically similar to the bursal secretory dendritic-like cells. A product with ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0910-x
更新日期：2004-09-01 00:00:00
abstract：:Dexamethasone (Dex) regulates osteoblastic and adipocytic differentiation in mesenchymal progenitor cells through regulation of Wnt/β-catenin signaling. To elucidate the regulatory mechanisms underlying the effects of Dex, we examine the expression of Axin2, which is an intracellular inhibitor of Wnt/β-catenin signali...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1696-5
更新日期：2013-12-01 00:00:00
abstract：:The antioxidant enzymes superoxide dismutase, glutathione peroxidase, and catalase were measured in the rete mirabile and gas gland epithelium area of the swim bladder of the toadfish Opsanus tau. When the concentration of enzyme in the swim bladder was compared with the concentration in other organs (kidney, heart, g...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210458
更新日期：1981-01-01 00:00:00
abstract：:During metamorphosis, the frog intestine goes through a dramatic shortening with extensive apoptosis and regeneration in the epithelial layer and connective tissue. Our aim was to study changes in the enteric nervous system represented by one inhibitory (vasoactive intestinal polypeptide; VIP) and one excitatory (subs...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0856-z
更新日期：2004-04-01 00:00:00
abstract：:Intracellular sporozoan parasites invade the host cell through the invagination of the plasma membrane of the host and a vacuole is formed which accommodates the entering parasite. The vacuole may disappear and the invaginated membrane of the host then becomes closely apposed to that of the parasite's own membrane. As...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219605
更新日期：1976-06-28 00:00:00
abstract：:Interstitial cells in the myenteric plexus and the deep muscular plexus of the small intestine of the c-kit mutant rats (Ws/Ws) and their normal siblings (+/+) were studied. c-Kit immunoreactivity was detected in two regions corresponding to the myenteric plexus and the deep muscular plexus in the jejunum of +/+ rats,...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051119
更新日期：1998-08-01 00:00:00
abstract：:The fine structure of the main excretory duct epithelium (MEDE) of female mouse submandibular gland was investigated by scanning and transmission electron microscopy and the results compared with the previously established structure of male mouse MEDE. A comparative analysis of the subepithelial capillaries of both se...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00300213
更新日期：1994-09-01 00:00:00
abstract：:Denervation of radial and ulnar arteries in the growing and adult domestic fowl was achieved by unilateral sectioning of the brachial plexus. Eight weeks later the denervated arteries and those of the contralateral wing were examined with light- and electron microscopy to determine the effect of denervation on arteria...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218955
更新日期：1987-12-01 00:00:00
abstract：:The size of various tubes within tubular organs such as the lung, vascular system and kidney must be finely tuned for the optimal delivery of gases, nutrients, waste and cells within the entire organism. Aberrant tube sizes lead to devastating human illnesses, such as polycystic kidney disease, fibrocystic breast dise...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1673-z
更新日期：2013-11-01 00:00:00
abstract：:The molecular cloning of a cDNA fragment synthesised from rat duodenal mRNA coding for cholecalcin (calbindin), a 9000 Mr vitamin D-induced calcium-binding protein (CaBP), has been previously described. DNA/RNA hybridisation assays have been used to examine CaBP mRNA production in the uterine horns and duodena of preg...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216546
更新日期：1987-01-01 00:00:00
abstract：:The distribution of P2X(2) purine receptor subunit immunoreactivity has been investigated in the mouse gastrointestinal tract. Immunoreactivity occurred in intraganglionic laminar endings (IGLEs) associated with myenteric ganglia throughout the gastrointestinal tract. In the esophagus, IGLEs supplied every myenteric g...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0715-3
更新日期：2003-05-01 00:00:00
abstract：:In the compound eye of Notonecta glauca, the backswimmer, there is a small ventral region in which the rhabdoms differ in structure from those in the other parts of the eye. Here, among other unusual features, there is a special orientation of the microvilli of the central rhabdomeres, i.e., in most of the median eye ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222373
更新日期：1983-01-01 00:00:00
abstract：:It is known that human and animal fibroblasts are able to induce the retraction of a fibrin clot. In the present study the correlation between (i) fibrin-fibroblasts during growth, (ii) the number of actin stress-lines in mouse fibroblasts during growth in culture, and (iii) the sensitivity of actin stress-lines to a ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218485
更新日期：1982-01-01 00:00:00
abstract：:Quantitative studies on the population of the gonadotropic cells in the pituitary of adult male rats were performed after trypsic dissociation of the pituitary glands and immunoenzymatic staining with anti-beta-LH or anti-beta-FSH antisera. Number, area and extinction of labelled cells were measured by use of an image...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217273
更新日期：1982-01-01 00:00:00
abstract：:A continuous cell line was previously obtained by Simian Virus (SV) 40 transformation of primary cultures of dissociated mouse fetal hypothalami. One clone from this cell line has been previously shown to possess some of the ultrastructural features, immunological properties and synthesizing capacities of magnocellula...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219699
更新日期：1976-08-16 00:00:00
