Abstract：
:The intrinsic limits of conventional ultrasound microbubble contrast agent greatly promoted the development and application of various nanomaterials for more efficient cancer ultrasound theranostics. Considerable successes have been achieved in the field of ultrasound molecular imaging and targeted therapy for tumor based on nanoparticulate theranostic agents. This review summarizes and discusses the emerging development on exploring organic and inorganic nanomaterials for ultrasound-based tumor diagnositic applications, and as synergistic agents for ultrasound targeted therapy in fighting cancer. The relationship between structure/composition and functionality of nanomaterials for ultrasound theranostic is discussed and revealed in detail. Finally, the further development and challenges facing clinical implementation of ultrasound nanomedicine are discussed. As a highly promising and valuable tumor-specific theranostic methodology, it is believed that ultrasound nanomedicine would pave a novel but efficient way for combating cancer.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Zhou LQ,Li P,Cui XW,Dietrich CFdoi
10.1016/j.canlet.2019.11.034subject
Has Abstractpub_date
2020-02-01 00:00:00pages
204-219eissn
0304-3835issn
1872-7980pii
S0304-3835(19)30589-0journal_volume
470pub_type
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