Abstract:
:This study investigated the relationship between clinicopathological or immunohistochemical factors and postoperative prognosis for Dukes' C colorectal cancer. Short-term survivors died from cancer within 2 years of surgery, whereas long-term survivors were disease-free for over 10 years. The groups differed in Ki-67 antigen and CEA expression in colon cancer, and CEA expression in rectal cancer that was limited to the metastatic lymph nodes. The immunohistochemical scores were higher in short-term survivors. Our data suggest that the characteristics of metastatic lymph nodes are important as a predictor of the aggressiveness of tumor behavior and that the expression of Ki-67 antigen or CEA there may be a useful indicators of patients' survival in Dukes' C colorectal cancer.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Ishida H,Miwa H,Tatsuta M,Masutani S,Imamura H,Shimizu J,Ezumi K,Kato H,Kawasaki T,Furukawa H,Kawakami Hdoi
10.1016/j.canlet.2003.10.032keywords:
subject
Has Abstractpub_date
2004-04-15 00:00:00pages
109-15issue
1eissn
0304-3835issn
1872-7980pii
S0304383503007481journal_volume
207pub_type
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