Dilution effect of the building area on energy intensity in urban residential buildings.

abstract：:Systematic exploration of cancer cell vulnerabilities can inform the development of novel cancer therapeutics. Here, through analysis of genome-scale loss-of-function datasets, we identify adenosine deaminase acting on RNA (ADAR or ADAR1) as an essential gene for the survival of a subset of cancer cell lines. ADAR1-de...

journal_title：Nature communications

authors： Gannon HS,Zou T,Kiessling MK,Gao GF,Cai D,Choi PS,Ivan AP,Buchumenski I,Berger AC,Goldstein JT,Cherniack AD,Vazquez F,Tsherniak A,Levanon EY,Hahn WC,Meyerson M

更新日期：2018-12-21 00:00:00

abstract：:Tunneling is a fundamental quantum process with no classical equivalent, which can compete with Coulomb interactions to give rise to complex phenomena. Phosphorus dopants in silicon can be placed with atomic precision to address the different regimes arising from this competition. However, they exploit wavefunctions r...

journal_title：Nature communications

authors： Voisin B,Bocquel J,Tankasala A,Usman M,Salfi J,Rahman R,Simmons MY,Hollenberg LCL,Rogge S

更新日期：2020-11-30 00:00:00

abstract：:Kidney organogenesis requires the tight control of proliferation, differentiation and apoptosis of renal progenitor cells. How the balance between these cellular decisions is achieved remains elusive. The Wilms' tumour suppressor Wt1 is required for progenitor survival, but the molecular cause for renal agenesis in mu...

journal_title：Nature communications

authors： Motamedi FJ,Badro DA,Clarkson M,Lecca MR,Bradford ST,Buske FA,Saar K,Hübner N,Brändli AW,Schedl A

更新日期：2014-07-17 00:00:00

abstract：:Here we benchmark device-to-device variation in field-effect transistors (FETs) based on monolayer MoS2 and WS2 films grown using metal-organic chemical vapor deposition process. Our study involves 230 MoS2 FETs and 160 WS2 FETs with channel lengths ranging from 5 μm down to 100 nm. We use statistical measures to eval...

journal_title：Nature communications

authors： Sebastian A,Pendurthi R,Choudhury TH,Redwing JM,Das S

更新日期：2021-01-29 00:00:00

abstract：:When two-dimensional crystals are brought into close proximity, their interaction results in reconstruction of electronic spectrum and crystal structure. Such reconstruction strongly depends on the twist angle between the crystals, which has received growing attention due to interesting electronic and optical properti...

journal_title：Nature communications

authors： Woods CR,Ares P,Nevison-Andrews H,Holwill MJ,Fabregas R,Guinea F,Geim AK,Novoselov KS,Walet NR,Fumagalli L

更新日期：2021-01-12 00:00:00

abstract：:Studying emerging or neglected pathogens is often challenging due to insufficient information and absence of genetic tools. Dual RNA-seq provides insights into host-pathogen interactions, and is particularly informative for intracellular organisms. Here we apply dual RNA-seq to Orientia tsutsugamushi (Ot), an obligate...

journal_title：Nature communications

authors： Mika-Gospodorz B,Giengkam S,Westermann AJ,Wongsantichon J,Kion-Crosby W,Chuenklin S,Wang LC,Sunyakumthorn P,Sobota RM,Subbian S,Vogel J,Barquist L,Salje J

更新日期：2020-07-03 00:00:00

abstract：:Constitutive activation of Wnt/β-catenin inhibits oligodendrocyte myelination. Tcf7l2/Tcf4, a β-catenin transcriptional partner, is required for oligodendrocyte differentiation. How Tcf7l2 modifies β-catenin signalling and controls myelination remains elusive. Here we define a stage-specific Tcf7l2-regulated transcrip...

journal_title：Nature communications

authors： Zhao C,Deng Y,Liu L,Yu K,Zhang L,Wang H,He X,Wang J,Lu C,Wu LN,Weng Q,Mao M,Li J,van Es JH,Xin M,Parry L,Goldman SA,Clevers H,Lu QR

更新日期：2016-03-09 00:00:00

abstract：:Most DNA in the genomes of higher organisms does not encode proteins, yet much is transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The biological significance of most lncRNAs is largely unclear. Here, we identify a lncRNA (SVALKA) in a cold-sensitive region of the Arabidopsis genome. Muta...

journal_title：Nature communications

authors： Kindgren P,Ard R,Ivanov M,Marquardt S

更新日期：2018-11-01 00:00:00

abstract：:Coelacanths are known for their evolutionary conservatism, and the body plan seen in Latimeria can be traced to late Middle Devonian Diplocercides, Holopterygius and presumably Euporosteus. However, the group's early history is unclear because of an incomplete fossil record. Until now, the only Early Devonian coelacan...

journal_title：Nature communications

authors： Zhu M,Yu X,Lu J,Qiao T,Zhao W,Jia L

更新日期：2012-04-10 00:00:00

abstract：:Somatic mutations contribute to tumorigenesis. Although these mutations occur in all proliferating cells, their accumulation under non-malignant conditions, such as in autoimmune disorders, has not been investigated. Here, we show that patients with newly diagnosed rheumatoid arthritis have expanded CD8+ T-cell clones...

journal_title：Nature communications

authors： Savola P,Kelkka T,Rajala HL,Kuuliala A,Kuuliala K,Eldfors S,Ellonen P,Lagström S,Lepistö M,Hannunen T,Andersson EI,Khajuria RK,Jaatinen T,Koivuniemi R,Repo H,Saarela J,Porkka K,Leirisalo-Repo M,Mustjoki S

更新日期：2017-06-21 00:00:00

abstract：:Electric fields can transform materials with respect to their structure and properties, enabling various applications ranging from batteries to spintronics. Recently electrolytic gating, which can generate large electric fields and voltage-driven ion transfer, has been identified as a powerful means to achieve electri...

journal_title：Nature communications

authors： Yi D,Wang Y,van ʼt Erve OMJ,Xu L,Yuan H,Veit MJ,Balakrishnan PP,Choi Y,N'Diaye AT,Shafer P,Arenholz E,Grutter A,Xu H,Yu P,Jonker BT,Suzuki Y

更新日期：2020-02-14 00:00:00

abstract：:Optogenetics has emerged as an alternative method for electrical control of the heart, where illumination is used to elicit a bioelectric response in tissue modified to express photosensitive proteins (opsins). This technology promises to enable evocation of spatiotemporally precise responses in targeted cells or tiss...

journal_title：Nature communications

authors： Boyle PM,Williams JC,Ambrosi CM,Entcheva E,Trayanova NA

更新日期：2013-01-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： López-Barneo J,Simon MC

更新日期：2020-02-25 00:00:00

abstract：:Selection rules are of vital importance in determining the basic optical properties of atoms, molecules and semiconductors. They provide general insights into the symmetry of the system and the nature of relevant electronic states. A two-dimensional electron gas in a magnetic field is a model system where optical tran...

journal_title：Nature communications

authors： Ju L,Wang L,Li X,Moon S,Ozerov M,Lu Z,Taniguchi T,Watanabe K,Mueller E,Zhang F,Smirnov D,Rana F,McEuen PL

更新日期：2020-06-10 00:00:00

abstract：:The ventral striatum has long been proposed as an integrator of biologically significant associative information to drive actions. Although inputs from the amygdala and hippocampus have been much studied, the role of prominent inputs from orbitofrontal cortex (OFC) are less well understood. Here, we recorded single-un...

journal_title：Nature communications

authors： Cooch NK,Stalnaker TA,Wied HM,Bali-Chaudhary S,McDannald MA,Liu TL,Schoenbaum G

更新日期：2015-05-21 00:00:00

abstract：:The ability to modulate nanoparticle (NP) assemblies with atomic precision is still lacking, which hinders us from creating hierarchical NP organizations with desired properties. In this work, a hierarchical fibrous (1D to 3D) assembly of Au NPs (21-gold atom, Au21) is realized and further modulated with atomic precis...

journal_title：Nature communications

authors： Li Q,Russell JC,Luo TY,Roy X,Rosi NL,Zhu Y,Jin R

更新日期：2018-09-24 00:00:00

abstract：:Autophagy can degrade cargos with the help of selective autophagy receptors such as p62/SQSTM1, which facilitates the degradation of ubiquitinated cargo. While the process of autophagy has been linked to aging, the impact of selective autophagy in lifespan regulation remains unclear. We have recently shown in Caenorha...

journal_title：Nature communications

authors： Kumsta C,Chang JT,Lee R,Tan EP,Yang Y,Loureiro R,Choy EH,Lim SHY,Saez I,Springhorn A,Hoppe T,Vilchez D,Hansen M

更新日期：2019-12-11 00:00:00

abstract：:In vivo liposomes, like other types of nanoparticles, acquire a totally new 'biological identity' due to the formation of a biomolecular coating known as the protein corona that depends on and modifies the liposomes' synthetic identity. The liposome-protein corona is a dynamic interface that regulates the interaction ...

journal_title：Nature communications

authors： Giulimondi F,Digiacomo L,Pozzi D,Palchetti S,Vulpis E,Capriotti AL,Chiozzi RZ,Laganà A,Amenitsch H,Masuelli L,Peruzzi G,Mahmoudi M,Screpanti I,Zingoni A,Caracciolo G

更新日期：2019-08-15 00:00:00

abstract：:Hybrid organic-inorganic perovskites have attractive optoelectronic properties including exceptional solar cell performance. The improved properties of perovskites have been attributed to polaronic effects involving stabilization of localized charge character by structural deformations and polarizations. Here we exami...

journal_title：Nature communications

authors： Park M,Neukirch AJ,Reyes-Lillo SE,Lai M,Ellis SR,Dietze D,Neaton JB,Yang P,Tretiak S,Mathies RA

更新日期：2018-06-28 00:00:00

abstract：:As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different types of cancer, chronic lymphocytic leukaemia and medulloblastoma, we conduct a benchmarking e...

journal_title：Nature communications

authors： Alioto TS,Buchhalter I,Derdak S,Hutter B,Eldridge MD,Hovig E,Heisler LE,Beck TA,Simpson JT,Tonon L,Sertier AS,Patch AM,Jäger N,Ginsbach P,Drews R,Paramasivam N,Kabbe R,Chotewutmontri S,Diessl N,Previti C,Schmidt S

更新日期：2015-12-09 00:00:00

abstract：:A common analysis of single-cell sequencing data includes clustering of cells and identifying differentially expressed genes (DEGs). How cell clusters are defined has important consequences for downstream analyses and the interpretation of results, but is often not straightforward. To address this difficulty, we prese...

journal_title：Nature communications

authors： Vandenbon A,Diez D

更新日期：2020-08-28 00:00:00

abstract：:Plant hormone cytokinins are perceived by a subfamily of sensor histidine kinases (HKs), which via a two-component phosphorelay cascade activate transcriptional responses in the nucleus. Subcellular localization of the receptors proposed the endoplasmic reticulum (ER) membrane as a principal cytokinin perception site,...

journal_title：Nature communications

authors： Kubiasová K,Montesinos JC,Šamajová O,Nisler J,Mik V,Semerádová H,Plíhalová L,Novák O,Marhavý P,Cavallari N,Zalabák D,Berka K,Doležal K,Galuszka P,Šamaj J,Strnad M,Benková E,Plíhal O,Spíchal L

更新日期：2020-08-27 00:00:00

abstract：:Telomerase elongates the telomeric G-strand to prevent telomere shortening through conventional DNA replication. However, synthesis of the complementary C-strand by DNA polymerase α is also required to maintain telomere length. Polymerase α cannot perform this role without the ssDNA binding complex CST (CTC1-STN1-TEN1...

journal_title：Nature communications

authors： Feng X,Hsu SJ,Bhattacharjee A,Wang Y,Diao J,Price CM

更新日期：2018-07-19 00:00:00

abstract：:The success of protein evolution campaigns is strongly dependent on the sequence context in which mutations are introduced, stemming from pervasive non-additive interactions between a protein's amino acids ('intra-gene epistasis'). Our limited understanding of such epistasis hinders the correct prediction of the funct...

journal_title：Nature communications

authors： Zurek PJ,Knyphausen P,Neufeld K,Pushpanath A,Hollfelder F

更新日期：2020-11-26 00:00:00

abstract：:Essential components of animal behaviour are modulated by dopaminergic (DA) and noradrenergic circuitry. In this study, we reveal at cellular resolution the complete set of projections ('projectome') of every single type of DA and noradrenergio neurons in the central nervous system of zebrafish larvae. The most extens...

journal_title：Nature communications

authors： Tay TL,Ronneberger O,Ryu S,Nitschke R,Driever W

更新日期：2011-01-25 00:00:00

abstract：:Artificial molecules containing just one or two electrons provide a powerful platform for studies of orbital and spin quantum dynamics in nanoscale devices. A well-known example of these dynamics is tunnelling of electrons between two coupled quantum dots triggered by mi...

journal_title：Nature communications

authors： Schreiber LR,Braakman FR,Meunier T,Calado V,Danon J,Taylor JM,Wegscheider W,Vandersypen LM

更新日期：2011-11-22 00:00:00

abstract：:β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles of the transcription factor Foxp1 in brown/beige adipocyte differentiation and thermogenesis. Adipose-specific deletion of Foxp1 leads to an increase of brown ad...

journal_title：Nature communications

authors： Liu P,Huang S,Ling S,Xu S,Wang F,Zhang W,Zhou R,He L,Xia X,Yao Z,Fan Y,Wang N,Hu C,Zhao X,Tucker HO,Wang J,Guo X

更新日期：2019-11-07 00:00:00

abstract：:The impact of discontinuation of anti-VEGF cancer therapy in promoting cancer metastasis is unknown. Here we show discontinuation of anti-VEGF treatment creates a time-window of profound structural changes of liver sinusoidal vasculatures, exhibiting hyper-permeability and enlarged open-pore sizes of the fenestrated e...

journal_title：Nature communications

authors： Yang Y,Zhang Y,Iwamoto H,Hosaka K,Seki T,Andersson P,Lim S,Fischer C,Nakamura M,Abe M,Cao R,Skov PV,Chen F,Chen X,Lu Y,Nie G,Cao Y

更新日期：2016-09-01 00:00:00

abstract：:Diatoms contribute roughly 20% of global primary production, but the factors determining their ability to adapt to global warming are unknown. Here we quantify the capacity for adaptation to warming in the marine diatom Thalassiosira pseudonana. We find that evolutionary rescue under severe (32 °C) warming is slow, bu...

journal_title：Nature communications

authors： Schaum CE,Buckling A,Smirnoff N,Studholme DJ,Yvon-Durocher G

更新日期：2018-04-30 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Wang ZH,Gong K,Liu X,Zhang Z,Sun X,Wei ZZ,Yu SP,Manfredsson FP,Sandoval IM,Johnson PF,Jia J,Wang JZ,Ye K

更新日期：2019-11-26 00:00:00