Emergent electric field control of phase transformation in oxide superlattices.

abstract：:Solitary, persistent wave packets called solitons hold potential to transfer information and energy across a wide range of spatial and temporal scales in physical, chemical, and biological systems. Mechanical solitons characteristically emerge either as a single wave packet or uncorrelated propagating topological enti...

journal_title：Nature communications

authors： Zhang Y,Li B,Zheng QS,Genin GM,Chen CQ

更新日期：2019-12-06 00:00:00

abstract：:Secondary multidrug transporters use ion concentration gradients to energize the removal from cells of various antibiotics. The Escherichia coli multidrug transporter MdfA exchanges a single proton with a single monovalent cationic drug molecule. This stoichiometry renders the efflux of divalent cationic drugs energet...

journal_title：Nature communications

authors： Fluman N,Adler J,Rotenberg SA,Brown MH,Bibi E

更新日期：2014-08-08 00:00:00

abstract：:To expand the toolbox of imaging in living cells, we have engineered a single-chain variable fragment binding the linear HA epitope with high affinity and specificity in vivo. The resulting probe, called the HA frankenbody, can light up in multiple colors HA-tagged nuclear, cytoplasmic, membrane, and mitochondrial pro...

journal_title：Nature communications

authors： Zhao N,Kamijo K,Fox PD,Oda H,Morisaki T,Sato Y,Kimura H,Stasevich TJ

更新日期：2019-07-03 00:00:00

abstract：:Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to the difficulty of their detection. Here, we develop a new high-throughput genotyping method based...

journal_title：Nature communications

authors： Giner-Delgado C,Villatoro S,Lerga-Jaso J,Gayà-Vidal M,Oliva M,Castellano D,Pantano L,Bitarello BD,Izquierdo D,Noguera I,Olalde I,Delprat A,Blancher A,Lalueza-Fox C,Esko T,O'Reilly PF,Andrés AM,Ferretti L,Puig M,Cáce

更新日期：2019-09-17 00:00:00

abstract：:Multiple myeloma (MM) is a plasma-cell neoplasm that is treated with high-dose chemotherapy, autologous stem cell transplant (ASCT) and long-term immunomodulatory drug (IMiD) maintenance. The presence of somatic mutations in the peripheral blood is termed clonal hematopoiesis of indeterminate potential (CHIP) and is a...

journal_title：Nature communications

authors： Mouhieddine TH,Sperling AS,Redd R,Park J,Leventhal M,Gibson CJ,Manier S,Nassar AH,Capelletti M,Huynh D,Bustoros M,Sklavenitis-Pistofidis R,Tahri S,Hornburg K,Dumke H,Itani MM,Boehner CJ,Liu CJ,AlDubayan SH,Reardon B

更新日期：2020-06-12 00:00:00

abstract：:In recent years, the concept of metamaterials has offered platforms for unconventional tailoring and manipulation of the light-matter interaction. Here we explore the notion of 'static optics', in which the electricity and magnetism are decoupled, while the fields are temporally dynamic. This occurs when both the rela...

journal_title：Nature communications

authors： Mahmoud AM,Engheta N

更新日期：2014-12-05 00:00:00

abstract：:Hybrid organic-inorganic perovskites have attractive optoelectronic properties including exceptional solar cell performance. The improved properties of perovskites have been attributed to polaronic effects involving stabilization of localized charge character by structural deformations and polarizations. Here we exami...

journal_title：Nature communications

authors： Park M,Neukirch AJ,Reyes-Lillo SE,Lai M,Ellis SR,Dietze D,Neaton JB,Yang P,Tretiak S,Mathies RA

更新日期：2018-06-28 00:00:00

abstract：:Clonal heterogeneity and evolution has major implications for disease progression and relapse in acute myeloid leukemia (AML). To model clonal dynamics in vivo, we serially transplanted 23 AML cases to immunodeficient mice and followed clonal composition for up to 15 months by whole-exome sequencing of 84 xenografts a...

journal_title：Nature communications

authors： Sandén C,Lilljebjörn H,Orsmark Pietras C,Henningsson R,Saba KH,Landberg N,Thorsson H,von Palffy S,Peña-Martinez P,Högberg C,Rissler M,Gisselsson D,Lazarevic V,Juliusson G,Ågerstam H,Fioretos T

更新日期：2020-02-05 00:00:00

abstract：:There is enormous interest in engineering topological photonic systems. Despite intense activity, most works on topological photonic states (and more generally bosonic states) amount in the end to replicating a well-known fermionic single-particle Hamiltonian. Here we show how the squeezing of light can lead to the fo...

journal_title：Nature communications

authors： Peano V,Houde M,Brendel C,Marquardt F,Clerk AA

更新日期：2016-03-02 00:00:00

abstract：:For the state-of-the-art quantum dot light-emitting diodes, while the ZnO nanoparticle layers can provide effective electron injections into quantum dots layers, the hole transporting materials usually cannot guarantee sufficient hole injection owing to the deep valence band of quantum dots. Developing proper hole tra...

journal_title：Nature communications

authors： Cao W,Xiang C,Yang Y,Chen Q,Chen L,Yan X,Qian L

更新日期：2018-07-04 00:00:00

abstract：:It is known that transient receptor potential ankyrin 1 (TRPA1) channels, expressed by nociceptors, contribute to neuropathic pain. Here we show that TRPA1 is also expressed in Schwann cells. We found that in mice with partial sciatic nerve ligation, TRPA1 silencing in nociceptors attenuated mechanical allodynia, with...

journal_title：Nature communications

authors： De Logu F,Nassini R,Materazzi S,Carvalho Gonçalves M,Nosi D,Rossi Degl'Innocenti D,Marone IM,Ferreira J,Li Puma S,Benemei S,Trevisan G,Souza Monteiro de Araújo D,Patacchini R,Bunnett NW,Geppetti P

更新日期：2017-12-01 00:00:00

abstract：:The temperature-jump technique, in which the sample is rapidly heated by a powerful laser pulse, has been widely used to probe the fast dynamics of folding of proteins and nucleic acids. However, the existing temperature-jump setups tend to involve sophisticated and expensive instrumentation, while providing only mode...

journal_title：Nature communications

authors： Polinkovsky ME,Gambin Y,Banerjee PR,Erickstad MJ,Groisman A,Deniz AA

更新日期：2014-12-17 00:00:00

abstract：:A broad range of dynamic metasurfaces has been developed for manipulating the intensity, phase and wavefront of electromagnetic radiation from microwaves to optical frequencies. However, most of these metasurfaces operate in single-input-output state. Here, we experimentally demonstrate a reconfigurable MEMS Fano reso...

journal_title：Nature communications

authors： Manjappa M,Pitchappa P,Singh N,Wang N,Zheludev NI,Lee C,Singh R

更新日期：2018-10-03 00:00:00

abstract：:Many crystals, such as those of metals, can transform from one symmetry into another having lower free energy via a diffusionless transformation. Here we create binary colloidal crystals consisting of polymer microspheres, pulled together by DNA bridges, that induce specific, reversible attractions between two species...

journal_title：Nature communications

authors： Casey MT,Scarlett RT,Rogers WB,Jenkins I,Sinno T,Crocker JC

更新日期：2012-01-01 00:00:00

abstract：:CRISPR/Cas9 has demonstrated a high-efficiency in site-specific gene targeting. However, potential off-target effects of the Cas9 nuclease represent a major safety concern for any therapeutic application. Here, we knock out the Tafazzin gene by CRISPR/Cas9 in human-induced pluripotent stem cells with 54% efficiency. W...

journal_title：Nature communications

authors： Yang L,Grishin D,Wang G,Aach J,Zhang CZ,Chari R,Homsy J,Cai X,Zhao Y,Fan JB,Seidman C,Seidman J,Pu W,Church G

更新日期：2014-11-26 00:00:00

abstract：:The reversible modification of cysteine residues by thioester formation with palmitate (S-palmitoylation) is an abundant lipid post-translational modification (PTM) in mammalian systems. S-palmitoylation has been observed on mitochondrial proteins, providing an intriguing potential connection between metabolic lipids ...

journal_title：Nature communications

authors： Kathayat RS,Cao Y,Elvira PD,Sandoz PA,Zaballa ME,Springer MZ,Drake LE,Macleod KF,van der Goot FG,Dickinson BC

更新日期：2018-01-23 00:00:00

abstract：:A Weyl semimetal possesses spin-polarized band-crossings, called Weyl nodes, connected by topological surface arcs. The low-energy excitations near the crossing points behave the same as massless Weyl fermions, leading to exotic properties like chiral anomaly. To have the transport properties dominated by Weyl fermion...

journal_title：Nature communications

authors： Xu N,Weng HM,Lv BQ,Matt CE,Park J,Bisti F,Strocov VN,Gawryluk D,Pomjakushina E,Conder K,Plumb NC,Radovic M,Autès G,Yazyev OV,Fang Z,Dai X,Qian T,Mesot J,Ding H,Shi M

更新日期：2016-03-17 00:00:00

abstract：:Nucleoplasmin (Npm) is a highly conserved histone chaperone responsible for the maternal storage and zygotic release of histones H2A/H2B. Npm contains a pentameric N-terminal core domain and an intrinsically disordered C-terminal tail domain. Though intrinsically disordered regions are common among histone chaperones,...

journal_title：Nature communications

authors： Warren C,Matsui T,Karp JM,Onikubo T,Cahill S,Brenowitz M,Cowburn D,Girvin M,Shechter D

更新日期：2017-12-20 00:00:00

abstract：:Carotenoid cleavage dioxygenases (CCDs) form hormones and signaling molecules. Here we show that a member of an overlooked plant CCD subfamily from rice, that we name Zaxinone Synthase (ZAS), can produce zaxinone, a novel apocarotenoid metabolite in vitro. Loss-of-function mutants (zas) contain less zaxinone, exhibit ...

journal_title：Nature communications

authors： Wang JY,Haider I,Jamil M,Fiorilli V,Saito Y,Mi J,Baz L,Kountche BA,Jia KP,Guo X,Balakrishna A,Ntui VO,Reinke B,Volpe V,Gojobori T,Blilou I,Lanfranco L,Bonfante P,Al-Babili S

更新日期：2019-02-18 00:00:00

abstract：:Nascent polypeptides can induce ribosome stalling, regulating downstream genes. Stalling of ErmBL peptide translation in the presence of the macrolide antibiotic erythromycin leads to resistance in Streptococcus sanguis. To reveal this stalling mechanism we obtained 3.6-Å-resolution cryo-EM structures of ErmBL-stalled...

journal_title：Nature communications

authors： Arenz S,Bock LV,Graf M,Innis CA,Beckmann R,Grubmüller H,Vaiana AC,Wilson DN

更新日期：2016-07-06 00:00:00

abstract：:Human pressures on the ocean are thought to be increasing globally, yet we know little about their patterns of cumulative change, which pressures are most responsible for change, and which places are experiencing the greatest increases. Managers and policymakers require such information to make strategic decisions and...

journal_title：Nature communications

authors： Halpern BS,Frazier M,Potapenko J,Casey KS,Koenig K,Longo C,Lowndes JS,Rockwood RC,Selig ER,Selkoe KA,Walbridge S

更新日期：2015-07-14 00:00:00

abstract：:Targeting of immunoglobulin E (IgE) represents an interesting approach for the treatment of allergic disorders. A high-affinity monoclonal anti-IgE antibody, ligelizumab, has recently been developed to overcome some of the limitations associated with the clinical use of the therapeutic anti-IgE antibody, omalizumab. H...

journal_title：Nature communications

authors： Gasser P,Tarchevskaya SS,Guntern P,Brigger D,Ruppli R,Zbären N,Kleinboelting S,Heusser C,Jardetzky TS,Eggel A

更新日期：2020-01-08 00:00:00

abstract：:Mutations in fused in sarcoma (FUS) lead to amyotrophic lateral sclerosis (ALS) with varying ages of onset, progression and severity. This suggests that unknown genetic factors contribute to disease pathogenesis. Here we show the identification of muscleblind as a novel modifier of FUS-mediated neurodegeneration in vi...

journal_title：Nature communications

authors： Casci I,Krishnamurthy K,Kour S,Tripathy V,Ramesh N,Anderson EN,Marrone L,Grant RA,Oliver S,Gochenaur L,Patel K,Sterneckert J,Gleixner AM,Donnelly CJ,Ruepp MD,Sini AM,Zuccaro E,Pennuto M,Pasinelli P,Pandey UB

更新日期：2019-12-06 00:00:00

abstract：:The ability to quickly spread a liquid across a surface and form a film is fundamental for a diverse range of technological processes, including printing, painting and spraying. Here we show that liquid dielectrophoresis or electrowetting can produce wetting on normally non-wetting surfaces, without needing modificati...

journal_title：Nature communications

authors： McHale G,Brown CV,Sampara N

更新日期：2013-01-01 00:00:00

abstract：:Quantum point contacts exhibit mysterious conductance anomalies in addition to well-known conductance plateaus at multiples of 2e(2)/h. These 0.7 and zero-bias anomalies have been intensively studied, but their microscopic origin in terms of many-body effects is still highly debated. Here we use the charged tip of a s...

journal_title：Nature communications

authors： Brun B,Martins F,Faniel S,Hackens B,Bachelier G,Cavanna A,Ulysse C,Ouerghi A,Gennser U,Mailly D,Huant S,Bayot V,Sanquer M,Sellier H

更新日期：2014-06-30 00:00:00

abstract：:Fluorescence imaging is one of the most versatile and widely used visualization methods in biomedical research. However, tissue autofluorescence is a major obstacle confounding interpretation of in vivo fluorescence images. The unusually long emission lifetime (5-13 μs) of photoluminescent porous silicon nanoparticles...

journal_title：Nature communications

authors： Gu L,Hall DJ,Qin Z,Anglin E,Joo J,Mooney DJ,Howell SB,Sailor MJ

更新日期：2013-01-01 00:00:00

abstract：:The demand for highly scalable, low-power devices for data storage and logic operations is strongly stimulating research into resistive switching as a novel concept for future non-volatile memory devices. To meet technological requirements, it is imperative to have a set of material design rules based on fundamental m...

journal_title：Nature communications

authors： Baeumer C,Schmitz C,Ramadan AH,Du H,Skaja K,Feyer V,Müller P,Arndt B,Jia CL,Mayer J,De Souza RA,Michael Schneider C,Waser R,Dittmann R

更新日期：2015-10-19 00:00:00

abstract：:The exploration of chemical space for new reactivity, reactions and molecules is limited by the need for separate work-up-separation steps searching for molecules rather than reactivity. Herein we present a system that can autonomously evaluate chemical reactivity within a network of 64 possible reaction combinations ...

journal_title：Nature communications

authors： Dragone V,Sans V,Henson AB,Granda JM,Cronin L

更新日期：2017-06-09 00:00:00

abstract：:Fullerene peapods, which are carbon nanotubes encapsulating fullerene molecules, can offer enhanced functionality with respect to empty nanotubes. Their prospective applications include, for example, data storage devices, single-electron transistors and spin-qubit arrays for quantum computing. However, the present inc...

journal_title：Nature communications

authors： Utko P,Ferone R,Krive IV,Shekhter RI,Jonson M,Monthioux M,Noé L,Nygård J

更新日期：2010-07-13 00:00:00

abstract：:Bipolaron states, in which two electrons or two holes occupy a single molecule or conjugated polymer segment, are typically considered to be negligible in organic semiconductor devices due to Coulomb repulsion between the two charges. Here we use charge modulation spectroscopy to reveal a bipolaron sheet density >1010...

journal_title：Nature communications

authors： Dhanker R,Gray CL,Mukhopadhyay S,Nunez S,Cheng CY,Sokolov AN,Giebink NC

更新日期：2017-12-21 00:00:00