Unveiling the hidden genetic diversity and chloroplast type of marine benthic ciliate Mesodinium species.

abstract：:The exopeptidases of family S46 are exceptional, as the closest homologs of these enzymes are the endopeptidases of clan PA. The three-dimensional structure of S46 enzymes is unknown and only one of the catalytic residues, the serine, has been identified. The catalytic histidine and aspartate residues are not experime...

journal_title：Scientific reports

authors： Suzuki Y,Sakamoto Y,Tanaka N,Okada H,Morikawa Y,Ogasawara W

更新日期：2014-03-06 00:00:00

abstract：:The overall goal of this work was to measure the efficacy of fMRI for predicting whether a dog would be a successful service dog. The training and imaging were performed in 49 dogs entering service training at 17-21 months of age. 33 dogs completed service training and were matched with a person, while 10 were release...

journal_title：Scientific reports

authors： Berns GS,Brooks AM,Spivak M,Levy K

更新日期：2017-03-07 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play diverse roles in biological processes. Aedes aegypti (Ae. aegypti), a blood-sucking mosquito, is the principal vector responsible for replication and transmission of arboviruses including dengue, Zika, and Chikungunya virus. Systematic identification and developmental characterisatio...

journal_title：Scientific reports

authors： Azlan A,Obeidat SM,Yunus MA,Azzam G

更新日期：2019-08-21 00:00:00

abstract：:Standard aquatic toxicity tests of chemicals are often limited by the chemicals' water solubility. Liposomes have been widely used in the pharmaceutical industry to overcome poor pharmacokinetics and biodistribution. In this work, liposomes were synthesized and used in an ecotoxicological context, as a tool to assure ...

journal_title：Scientific reports

authors： Castro M,Lindqvist D

更新日期：2020-06-16 00:00:00

abstract：:Validation of imaging contrast agents, such as fluorescently labeled imaging antibodies, has been recognized as a critical challenge in clinical and preclinical studies. As the number of applications for imaging antibodies grows, these materials are increasingly being subjected to careful scrutiny. Antibody fluorescen...

journal_title：Scientific reports

authors： Zhou H,Tourkakis G,Shi D,Kim DM,Zhang H,Du T,Eades WC,Berezin MY

更新日期：2017-02-02 00:00:00

abstract：:A numerical method of solving for the elastic wave eigenmodes in acoustic waveguides of arbitrary cross-section is presented. Operating under the assumptions of linear, isotropic materials, it utilizes a finite-difference method on a staggered grid to solve for the acoustic eigenmodes (field and frequency) of the vect...

journal_title：Scientific reports

authors： Dostart N,Liu Y,Popović MA

更新日期：2017-12-13 00:00:00

abstract：:We investigate theoretically the two-photon absorption (TPA) for circular graphene quantum dots (GQDs) with the edge of armchair and zigzag on the basis of electronic energy states obtained by solving the Dirac-Weyl equation numerically under finite difference method. The expressions for TPA cross section are derived ...

journal_title：Scientific reports

authors： Feng X,Li Z,Li X,Liu Y

更新日期：2016-09-15 00:00:00

abstract：:Light beams with extraordinary spatial structures, such as the Airy beam (AB), the Bessel-Gaussian beam (BGB) and the Laguerre-Gaussian beam (LGB), are widely studied and applied in many optical scenarios. We report on preparation of light beams with controllable spatial structures through sum frequency generation (SF...

journal_title：Scientific reports

authors： Zhou ZY,Li Y,Ding DS,Jiang YK,Zhang W,Shi S,Shi BS,Guo GC

更新日期：2014-07-10 00:00:00

abstract：:New strategies are needed to develop better tools to control TB, including identification of novel antigens for vaccination. Such Mtb antigens must be expressed during Mtb infection in the major target organ, the lung, and must be capable of eliciting human immune responses. Using genome-wide transcriptomics of Mtb in...

journal_title：Scientific reports

authors： Coppola M,van Meijgaarden KE,Franken KL,Commandeur S,Dolganov G,Kramnik I,Schoolnik GK,Comas I,Lund O,Prins C,van den Eeden SJ,Korsvold GE,Oftung F,Geluk A,Ottenhoff TH

更新日期：2016-11-28 00:00:00

abstract：:Viruses exploit host factors and environment for their efficient replication. The virus-host interaction mechanisms for achieving an optimal hepatitis B virus (HBV) replication have been largely unknown. Here, a single cell cloning revealed that HepAD38 cells, a widely-used HBV-inducible cell line, contain cell clones...

journal_title：Scientific reports

authors： Iwamoto M,Cai D,Sugiyama M,Suzuki R,Aizaki H,Ryo A,Ohtani N,Tanaka Y,Mizokami M,Wakita T,Guo H,Watashi K

更新日期：2017-09-06 00:00:00

abstract：:Ferroelectric tunneling junctions (FTJs) with tunable tunneling electroresistance (TER) are promising for many emerging applications, including non-volatile memories and neurosynaptic computing. One of the key challenges in FTJs is the balance between the polarization value and the tunneling current. In order to achie...

journal_title：Scientific reports

authors： Ryu H,Wu H,Rao F,Zhu W

更新日期：2019-12-31 00:00:00

abstract：:Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical ...

journal_title：Scientific reports

authors： Li J,Fejes P,Lorenser D,Quirk BC,Noble PB,Kirk RW,Orth A,Wood FM,Gibson BC,Sampson DD,McLaughlin RA

更新日期：2018-10-04 00:00:00

abstract：:Stress variation induced bandgap tuning and surface wettability switching of spinel nickel ferrite (NiFe2O4, NFO) films were demonstrated and directly driven by phase transition via a post-annealing process. Firstly, the as-deposited NFO films showed hydrophilic surface with water contact angle (CA) value of 80 ± 1°. ...

journal_title：Scientific reports

authors： Tong SK,Chi PW,Kung SH,Wei DH

更新日期：2018-01-22 00:00:00

abstract：:Dental caries is an important public health problem worldwide. This study aims to prove how preventive therapies reduce the onset of caries in adult patients, and to identify patients with high or low risk of caries by using Classification and Regression Trees based survival analysis (survival CART). A clinical data s...

journal_title：Scientific reports

authors： Arino M,Ito A,Fujiki S,Sugiyama S,Hayashi M

更新日期：2016-07-06 00:00:00

abstract：:The study aims to evaluate the effectiveness of local injection of autologous platelet rich plasma (A-PRP) as a treatment for women suffering from stress urinary incontinence (SUI). In a prospective intervention study, twenty consecutive women suffering from SUI were treated with A-PRP injection at anterior vaginal wa...

journal_title：Scientific reports

authors： Long CY,Lin KL,Shen CR,Ker CR,Liu YY,Loo ZX,Hsiao HH,Lee YC

更新日期：2021-01-15 00:00:00

abstract：:Hydrogen sulfide (H2S) signaling has been considered a key regulator of plant developmental processes and defenses. In this study, we demonstrate that high levels of H2S inhibit auxin transport and lead to alterations in root system development. H2S inhibits auxin transport by altering the polar subcellular distributi...

journal_title：Scientific reports

authors： Jia H,Hu Y,Fan T,Li J

更新日期：2015-02-05 00:00:00

abstract：:Academic research on dinoflagellate, the primary causative agent of harmful algal blooms (HABs), is often hindered by the coexistence with bacteria in laboratory cultures. The development of axenic dinoflagellate cultures is challenging and no universally accepted method suit for different algal species. In this study...

journal_title：Scientific reports

authors： Lee TC,Chan PL,Tam NF,Xu SJ,Lee FW

更新日期：2021-01-08 00:00:00

abstract：:There is a global concern about the effects of climate change driven shifts in species phenology on crop pests. Using geographically and temporally extensive data set of moth trap catches and temperatures across the cotton growing states of India, we predicted the phenology of cotton pink bollworm Pectinophora gossypi...

journal_title：Scientific reports

authors： Fand BB,Nagrare VS,Bal SK,Naik VCB,Naikwadi BV,Mahule DJ,Gokte-Narkhedkar N,Waghmare VN

更新日期：2021-01-11 00:00:00

abstract：:In this work we have studied the effects of pharmacological concentrations of melatonin (1 µM-1 mM) on pancreatic stellate cells (PSC). Cell viability was analyzed by AlamarBlue test. Production of reactive oxygen species (ROS) was monitored following CM-H2DCFDA and MitoSOX Red-derived fluorescence. Total protein carb...

journal_title：Scientific reports

authors： Gonzalez A,Estaras M,Martinez-Morcillo S,Martinez R,García A,Estévez M,Santofimia-Castaño P,Tapia JA,Moreno N,Pérez-López M,Míguez MP,Blanco-Fernández G,Lopez-Guerra D,Fernandez-Bermejo M,Mateos JM,Vara D,Roncero V,Sali

更新日期：2020-04-14 00:00:00

abstract：:In this study, the effect of post-deposition tetrafluoromethane (CF4) plasma treatment on the physical and electrical characteristics of an In2TiO5 based electrolyte-insulator-semiconductor (EIS) sensor was investigated. Post-deposition CF4 plasma treatment typically improved the crystalline structure and repaired dan...

journal_title：Scientific reports

authors： Lin CF,Kao CH,Lin CY,Liu CS,Liu YW

更新日期：2019-02-28 00:00:00

abstract：:Hybrid carbon films composed of graphene film and porous carbon film may give full play to the advantages of both carbon materials, and have great potential for application in energy storage and conversion devices. Unfortunately, there are very few reports on fabrication of hybrid carbon films. Here we demonstrate a s...

journal_title：Scientific reports

authors： Wei H,Wei S,Tian W,Zhu D,Liu Y,Yuan L,Li X

更新日期：2014-11-14 00:00:00

abstract：:The CRISPR/Cas9 system is widely used to generate gene-edited animals. Here, we developed an efficient system for generating genetically modified mice using maternal Cas9 from Cas9 transgenic mice. Using this system, we achieved lower mosaicism and higher rates of knock-in success, gene-editing, and birth compared to ...

journal_title：Scientific reports

authors： Sakurai T,Kamiyoshi A,Kawate H,Watanabe S,Sato M,Shindo T

更新日期：2020-01-23 00:00:00

abstract：:We recently showed that spinal cord injury (SCI) leads to a decrease in mRNA editing of serotonin receptor 2C (5-HT2CR) contributing to post-SCI spasticity. Here we study post-SCI mRNA editing and global gene expression using massively parallel sequencing. Evidence is presented that the decrease in 5-HT2CR editing is ...

journal_title：Scientific reports

authors： Di Narzo AF,Kozlenkov A,Ge Y,Zhang B,Sanelli L,May Z,Li Y,Fouad K,Cardozo C,Koonin EV,Bennett DJ,Dracheva S

更新日期：2015-07-30 00:00:00

abstract：:Nuclear receptor corepressor 1 (NCOR1) is a transcriptional regulator bridging repressive chromatin modifying enzymes with transcription factors. NCOR1 regulates many biological processes, however its role in T cells is not known. Here we show that Cd4-Cre-mediated deletion of NCOR1 (NCOR1 cKOCd4) resulted in a reduct...

journal_title：Scientific reports

authors： Müller L,Hainberger D,Stolz V,Hamminger P,Hassan H,Preglej T,Boucheron N,Sakaguchi S,Wiegers GJ,Villunger A,Auwerx J,Ellmeier W

更新日期：2017-11-21 00:00:00

abstract：:Sirtuins are NAD(+) dependent lysine deacylases involved in many regulatory processes such as control of metabolic pathways, DNA repair and stress response. Modulators of sirtuin activity are required as tools for uncovering the biological function of these enzymes and as potential therapeutic agents. Systematic disco...

journal_title：Scientific reports

authors： Schuster S,Roessler C,Meleshin M,Zimmermann P,Simic Z,Kambach C,Schiene-Fischer C,Steegborn C,Hottiger MO,Schutkowski M

更新日期：2016-03-04 00:00:00

abstract：:The impact of ctDNA changes after chemotherapy on the clinical outcomes of patients with metastatic colorectal cancer (mCRC) remains unclear. The present study evaluated the clinical implications of the early change in ctDNA levels as a predictor of objective response and clinical outcome in mCRC patients who received...

journal_title：Scientific reports

authors： Osumi H,Shinozaki E,Yamaguchi K,Zembutsu H

更新日期：2019-11-22 00:00:00

abstract：:The early replication of some orally-acquired prion strains upon stromal-derived follicular dendritic cells (FDC) within the small intestinal Peyer's patches is essential to establish host infection, and for the disease to efficiently spread to the brain. Factors that influence the early accumulation of prions in Peye...

journal_title：Scientific reports

authors： Sánchez-Quintero A,Bradford BM,Maizels R,Donaldson DS,Mabbott NA

更新日期：2019-04-30 00:00:00

abstract：:Previous studies have established that an increased Th-9 response creates a hostile environment for nematode parasites. Given that IL-23, a cytokine required for maintenance of the IL-17-secreting phenotype, has inhibitory effects on IL-9 production, we hypothesized that reducing circulating IL-23 by treatment with an...

journal_title：Scientific reports

authors： Gomez-Samblas M,Bernal D,Bolado-Ortiz A,Vilchez S,Bolás-Fernández F,Espino AM,Trelis M,Osuna A

更新日期：2018-05-17 00:00:00

abstract：:The stethoscope is used as first line diagnostic tool in assessment of patients with pulmonary symptoms. However, there is much debate about the diagnostic accuracy of this instrument. This meta-analysis aims to evaluate the diagnostic accuracy of lung auscultation for the most common respiratory pathologies. Studies ...

journal_title：Scientific reports

authors： Arts L,Lim EHT,van de Ven PM,Heunks L,Tuinman PR

更新日期：2020-04-30 00:00:00

abstract：:A high specificity aptamer-ligand biorecognition and binding system to monitor of dexamethasone (DXN) was developed. The detection principle was based on a label-free electrochemical aptasensor. The selection of the aptamer was successfully performed by the systematic evolution of ligands through exponential enrichmen...

journal_title：Scientific reports

authors： Mehennaoui S,Poorahong S,Jimenez GC,Siaj M

更新日期：2019-04-29 00:00:00