Multicenter study on caries risk assessment in adults using survival Classification and Regression Trees.

abstract：:Traffic-related air pollution is known to be associated with skin aging manifestations. We previously found that the use of fossil fuels was associated with skin aging, but no direct link between indoor air pollutants and skin aging manifestations has ever been shown. Here we directly measured the indoor PM2.5 exposur...

journal_title：Scientific reports

authors： Ding A,Yang Y,Zhao Z,Hüls A,Vierkötter A,Yuan Z,Cai J,Zhang J,Gao W,Li J,Zhang M,Matsui M,Krutmann J,Kan H,Schikowski T,Jin L,Wang S

更新日期：2017-11-10 00:00:00

abstract：:Adolescence is a critical period for the development of higher-order cognitive functions. Unlike in humans, very limited tools are available to assess such cognitive abilities in adolescent rodents. We implemented a modified 5-Choice Serial Reaction Time Task (5CSRTT) to selectively measure attentiveness, impulsivity,...

journal_title：Scientific reports

authors： Ciampoli M,Contarini G,Mereu M,Papaleo F

更新日期：2017-08-30 00:00:00

abstract：:Telomere length (TL) is linked to various age-related diseases, but little is known about telomeres in gestational diabetes mellitus (GDM). We surveyed 509 subjects (113 GDM patients and 396 frequency matched controls) in Nanjing Drum Tower Hospital, Jiangsu province of eastern China. Relative telomere length (RTL) of...

journal_title：Scientific reports

authors： Weng Q,Deng K,Wu F,Gan M,Li J,Dai Y,Jiang Y,Chen J,Dai J,Ma H,Hu Z,Shen H,Du J,Hu Y,Jin G

更新日期：2019-06-11 00:00:00

abstract：:The aim of this study was to explore whether rotational three-dimensional (3D) visualization of optical coherence tomography angiography (OCTA) volume data may yield valuable information regarding diabetic retinal microaneurysm (MA) characteristics. In this retrospective, observational study, we collected data from 20...

journal_title：Scientific reports

authors： Borrelli E,Sacconi R,Brambati M,Bandello F,Querques G

更新日期：2019-11-14 00:00:00

abstract：:We hereby report for the first time on the design, manufacturing and testing of a three-dimensional (3D) nearly-periodic, locally resonant phononic crystal (PnC). Most of the research effort on PnCs and metamaterials has been focused on the enhanced dynamic properties arising from their periodic design. Lately, additi...

journal_title：Scientific reports

authors： Meng H,Bailey N,Chen Y,Wang L,Ciampa F,Fabro A,Chronopoulos D,Elmadih W

更新日期：2020-11-04 00:00:00

abstract：:Cerebrospinal fluid (CSF) biomarkers are useful in the diagnosis and the prediction of progression of several neurodegenerative diseases. Among them, CSF neurofilament light (NfL) protein has particular interest, as its levels reflect neuroaxonal degeneration, a common feature in various neurodegenerative diseases. In...

journal_title：Scientific reports

authors： Delaby C,Alcolea D,Carmona-Iragui M,Illán-Gala I,Morenas-Rodríguez E,Barroeta I,Altuna M,Estellés T,Santos-Santos M,Turon-Sans J,Muñoz L,Ribosa-Nogué R,Sala-Matavera I,Sánchez-Saudinos B,Subirana A,Videla L,Benejam B,Si

更新日期：2020-06-08 00:00:00

abstract：:Spin torque oscillator (STO) has been attracting a great deal of attention as a candidate for the next generation microwave signal sources for various modern electronics systems since its advent. However, the phase noise of STOs under free running oscillation is still too large to be used in practical microwave applic...

journal_title：Scientific reports

authors： Tamaru S,Kubota H,Yakushiji K,Yuasa S,Fukushima A

更新日期：2015-12-11 00:00:00

abstract：:This prospective study investigates whether measurement of plasma intestinal-fatty acid binding protein (I-FABP), a sensitive marker for small intestinal epithelial damage, improves non-invasive diagnosing of celiac disease (CD), and whether I-FABP levels are useful to evaluate mucosal healing in patients on a gluten-...

journal_title：Scientific reports

authors： Adriaanse MPM,Mubarak A,Riedl RG,Ten Kate FJW,Damoiseaux JGMC,Buurman WA,Houwen RHJ,Vreugdenhil ACE,Celiac Disease Study Group.

更新日期：2017-08-17 00:00:00

abstract：:We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1-42), tTau and pTau CSF concentrat...

journal_title：Scientific reports

authors： Blennow K,Shaw LM,Stomrud E,Mattsson N,Toledo JB,Buck K,Wahl S,Eichenlaub U,Lifke V,Simon M,Trojanowski JQ,Hansson O

更新日期：2019-12-13 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron loss that ultimately leads to fatal paralysis. Reducing levels or function of the tyrosine kinase, ephrin type-A receptor 4 (EphA4), has been suggested as a potential approach for slowing disease progression in ALS. Becaus...

journal_title：Scientific reports

authors： Dominguez SL,Earr T,Dourado M,Ngu H,Meilandt WJ,Hanson JE

更新日期：2020-09-24 00:00:00

abstract：:The accident at the Fukushima Daiichi nuclear power plant caused serious radiocesium ((137)Cs) contamination of forest ecosystems located in mountainous and hilly regions with steep terrain. To understand topographic effects on the redistribution and accumulation of (137)Cs on forest floor, we investigated the distrib...

journal_title：Scientific reports

authors： Koarashi J,Atarashi-Andoh M,Takeuchi E,Nishimura S

更新日期：2014-10-31 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Guo Z,Liu H,Ni H,Wang X,Su M,Guo W,Wang K,Jiang T,Qian Y

更新日期：2020-05-20 00:00:00

abstract：:αβ T cells respond to peptide epitopes presented by major histocompatibility complex (MHC) molecules. The role of T cell receptor (TCR) germline complementarity determining regions (CDR1 and 2) in MHC restriction is not well understood. Here, we examine T cell development, MHC restriction and antigen recognition where...

journal_title：Scientific reports

authors： Attaf M,Holland SJ,Bartok I,Dyson J

更新日期：2016-10-24 00:00:00

abstract：:The objective of this study was to evaluate the clinical ability of Near-Infrared Light-Transillumination (NILT) for approximal dentinal caries detection and to compare with direct digital-radiography (DDR), as well as to determine whether the combination of both techniques improves the diagnostic capacity of the lesi...

journal_title：Scientific reports

authors： Melo M,Pascual A,Camps I,Ata-Ali F,Ata-Ali J

更新日期：2019-10-02 00:00:00

abstract：:(E)-Methyl-N'-nitrobenzylidene-benzenesulfonohydrazide (MNBBSH) compounds were synthesized using a condensation procedure from the derivatives of nitrobenzaldehyde and 4-Methyl-benzenesulfonylhydrazine, which crystallized in ethanol and methanol as well as characterized by FTIR, UV-Vis, 1H-NMR, and 13C-NMR. MNBBSH str...

journal_title：Scientific reports

authors： Hussain MM,Rahman MM,Arshad MN,Asiri AM

更新日期：2017-07-19 00:00:00

abstract：:Diabetes mellitus (DM) during pregnancy can result in fetal overgrowth, likely due to placental dysfunction, which has health consequences for the infant. Here we test our prediction from previous work using a placental cell line that high glucose concentrations affect placental lipid metabolism. Placentas from women ...

journal_title：Scientific reports

authors： Hulme CH,Nicolaou A,Murphy SA,Heazell AEP,Myers JE,Westwood M

更新日期：2019-10-01 00:00:00

abstract：:Resistance to adjuvant systemic treatment, including taxanes (docetaxel and paclitaxel) is a major clinical problem for breast cancer patients. lncRNAs (long non-coding RNAs) are non-coding transcripts, which have recently emerged as important players in a variety of biological processes, including cancer development ...

journal_title：Scientific reports

authors： Huang P,Li F,Li L,You Y,Luo S,Dong Z,Gao Q,Wu S,Brünner N,Stenvang J

更新日期：2018-12-19 00:00:00

abstract：:Silica columns from PCR purification and gel extraction kits are widely used in laboratories worldwide to assist in gene cloning. However, the use of these columns can generate plastic waste that has an environmental impact due to their one-off design and massive consumption. Thus, it is important to develop a novel m...

journal_title：Scientific reports

authors： Zhou Y,Zhang Y,He W,Wang J,Peng F,Huang L,Zhao S,Deng W

更新日期：2018-08-27 00:00:00

abstract：:In a single glass of champagne about a million bubbles nucleate on the wall and rise towards the surface. When these bubbles reach the surface and rupture, they project a multitude of tiny droplets in the form of a particular aerosol holding a concentrate of wine aromas. Based on the model experiment of a single bubbl...

journal_title：Scientific reports

authors： Ghabache E,Liger-Belair G,Antkowiak A,Séon T

更新日期：2016-04-29 00:00:00

abstract：:Based on the geological conditions of overburden rock, the dynamic development law of overburden breakage was investigated by theoretical analysis and similarity model experiments in this paper. The formula of the compressive strength and No. ratio was obtained by testing the compressive strength of cylinder samples o...

journal_title：Scientific reports

authors： Zhu H,Fang S,Huo Y,Guo J,Wu Y,Hu L

更新日期：2020-04-16 00:00:00

abstract：:Size shifts may be a by-product of alterations in life history traits driven by natural selection. Although this approach has been proposed for islands, it has not yet been explored in continental faunas. The trends towards size decrease experienced by some hipparionins constitute a good case study for the application...

journal_title：Scientific reports

authors： Orlandi-Oliveras G,Nacarino-Meneses C,Koufos GD,Köhler M

更新日期：2018-11-21 00:00:00

abstract：:Reconstructing diet is critical to understanding hominin adaptations. Isotopic and functional morphological analyses of early hominins are compatible with consumption of hard foods, such as mechanically-protected seeds, but dental microwear analyses are not. The protective shells surrounding seeds are thought to induc...

journal_title：Scientific reports

authors： van Casteren A,Strait DS,Swain MV,Michael S,Thai LA,Philip SM,Saji S,Al-Fadhalah K,Almusallam AS,Shekeban A,McGraw WS,Kane EE,Wright BW,Lucas PW

更新日期：2020-01-17 00:00:00

abstract：:Inhalation exposure to airborne respirable crystalline silica (RCS) poses major health risks in many industrial environments. There is a need for new sensitive instruments and methods for in-field or near real-time measurement of crystalline silica aerosol. The objective of this study was to develop an approach, using...

journal_title：Scientific reports

authors： Wei S,Kulkarni P,Ashley K,Zheng L

更新日期：2017-10-24 00:00:00

abstract：:Understanding how animals respond to injury and how wounds heal remains a challenge. These questions can be addressed using genetically tractable animals, including the nematode Caenorhabditis elegans. Given its small size, the current methods for inflicting wounds in a controlled manner are demanding. To facilitate a...

journal_title：Scientific reports

authors： Belougne J,Ozerov I,Caillard C,Bedu F,Ewbank JJ

更新日期：2020-02-27 00:00:00

abstract：:Emergent phases in the two-dimensional electron gas (2DEG) formed at the interface between two insulating oxides have attracted great attention in the past decade. We present ab-initio electronic structure calculations for the interface between a Mott insulator GdTiO3 (GTO) and a band insulator SrTiO3 (STO) and compar...

journal_title：Scientific reports

authors： Banerjee H,Banerjee S,Randeria M,Saha-Dasgupta T

更新日期：2015-12-22 00:00:00

abstract：:To evaluate crop rotation effects on maize seedling performance and its associated microbiome, maize plants were grown in the greenhouse in soils preceded by either maize, pea, soybean or sunflower. Soils originated from a replicated field experiment evaluating different four-year rotation combinations. In the greenho...

journal_title：Scientific reports

authors： Benitez MS,Osborne SL,Lehman RM

更新日期：2017-11-16 00:00:00

abstract：:Activation of the inflammasome is involved in the progression of retinal degenerative diseases, in particular, in the pathogenesis of Age-Related Macular Degeneration (AMD), with NLRP3 activation the focus of many investigations. In this study, we used genetic and pharmacological approaches to explore the role of the ...

journal_title：Scientific reports

authors： Wooff Y,Fernando N,Wong JHC,Dietrich C,Aggio-Bruce R,Chu-Tan JA,Robertson AAB,Doyle SL,Man SM,Natoli R

更新日期：2020-02-10 00:00:00

abstract：:Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define roles for TNTs in stress adaptation and treatment resistance in prostate cancer (PCa). Androgen receptor (AR) blockade and metabolic stress induce TNTs, but not in normal prostatic epithel...

journal_title：Scientific reports

authors： Kretschmer A,Zhang F,Somasekharan SP,Tse C,Leachman L,Gleave A,Li B,Asmaro I,Huang T,Kotula L,Sorensen PH,Gleave ME

更新日期：2019-05-24 00:00:00

abstract：:In photodynamic therapy (PDT), cells are impregnated with a photosensitizing agent that is activated by light irradiation, thereby photochemically generating reactive oxygen species (ROS). The amounts of ROS produced depends on the PDT dose and the nature of the photosensitizer. Although high levels of ROS are cytotox...

journal_title：Scientific reports

authors： Kushibiki T,Tu Y,Abu-Yousif AO,Hasan T

更新日期：2015-08-17 00:00:00

abstract：:Standard electroporation with pulses in milliseconds has been used as an effective tool to deliver drugs or genetic probes into cells, while irreversible electroporation with nanosecond pulses is explored to alter intracellular activities for pulse-induced apoptosis. A combination treatment, long nanosecond pulses fol...

journal_title：Scientific reports

authors： Chang AY,Liu X,Tian H,Hua L,Yang Z,Wang S

更新日期：2020-04-08 00:00:00