Comparative Transcriptome Analysis of Gene Expression Patterns in Tomato Under Dynamic Light Conditions.

abstract：:The development of high-throughput sequencing technologies and screening of big patient cohorts with familial and sporadic amyotrophic lateral sclerosis (ALS) led to the identification of a significant number of genetic variants, which are sometimes difficult to interpret. The American College of Medical Genetics and ...

journal_title：Genes

authors： Lattante S,Marangi G,Doronzio PN,Conte A,Bisogni G,Zollino M,Sabatelli M

更新日期：2020-09-24 00:00:00

abstract：:DNA methylation is an essential part of the epigenome chromatin modification network, which also comprises several covalent histone protein post-translational modifications. All these modifications are highly interconnected, because the writers and erasers of one mark, DNA methyltransferases (DNMTs) and ten eleven tra...

journal_title：Genes

authors： Jeltsch A,Broche J,Bashtrykov P

更新日期：2018-11-21 00:00:00

abstract：:Plant genomes generated by Sanger and Next Generation Sequencing (NGS) have provided insight into species diversity and evolution. However, Sanger sequencing is limited in its applications due to high cost, labor intensity, and low throughput, while NGS reads are too short to resolve abundant repeats and polyploidy, l...

journal_title：Genes

authors： Li C,Lin F,An D,Wang W,Huang R

更新日期：2017-12-28 00:00:00

abstract：:In contrast to the amazing exponential growth in knowledge related to long non-coding RNAs (lncRNAs) involved in cell homeostasis or dysregulated pathological states, little is known so far about the links between the chemical modifications occurring in lncRNAs and their function. Generally, ncRNAs are post-transcript...

journal_title：Genes

authors： Dinescu S,Ignat S,Lazar AD,Constantin C,Neagu M,Costache M

更新日期：2019-01-16 00:00:00

abstract：:Transcriptional activation of eukaryotic genes is accompanied, in general, by a change in the sensitivity of promoter chromatin to endonucleases. The structural basis of this alteration has remained elusive for decades; but the change has been viewed as a transformation of one structure into another, from "closed" to ...

journal_title：Genes

authors： Boeger H,Shelansky R,Patel H,Brown CR

更新日期：2015-06-30 00:00:00

abstract：:Staphylococcus aureus is a major human pathogen and an important cause of livestock infections. More than 20 staphylococcal enterotoxins with emetic activity can be produced by specific strains responsible for staphylococcal food poisoning, one of the most common food-borne diseases. Whole genome sequencing provides a...

journal_title：Genes

authors： Macori G,Bellio A,Bianchi DM,Chiesa F,Gallina S,Romano A,Zuccon F,Cabrera-Rubio R,Cauquil A,Merda D,Auvray F,Decastelli L

更新日期：2019-12-27 00:00:00

abstract：:Adverse environmental exposures in pregnancy can significantly alter the development of the fetus resulting in impaired child neurodevelopment. Such exposures can lead to epigenetic alterations like DNA methylation, which may be a marker of poor cognitive, motor and behavioral outcomes in the infant. Here we review st...

journal_title：Genes

authors： Hodyl NA,Roberts CT,Bianco-Miotto T

更新日期：2016-12-03 00:00:00

abstract：:The superior performance of hybrids to parents, termed heterosis, has been widely utilized in animal and plant breeding programs, but the molecular mechanism underlying heterosis remains an enigma. RNA-Seq provides a novel way to investigate heterosis at the transcriptome-wide level, because gene expression functions ...

journal_title：Genes

authors： Zhuo Z,Lamont SJ,Abasht B

更新日期：2019-01-07 00:00:00

abstract：:Exposure to Formaldehyde (FA) results in many pathophysiological symptoms, however the underlying mechanisms are not well understood. Given the complicated modulatory role of intestinal microbiota on human health, we hypothesized that interactions between FA and the gut microbiome may account for FA's toxicity. Balb/c...

journal_title：Genes

authors： Guo J,Zhao Y,Jiang X,Li R,Xie H,Ge L,Xie B,Yang X,Zhang L

更新日期：2018-04-03 00:00:00

abstract：:Oral vaccination is a practical method for the active immunization of farmed fish in the matter of animal welfare and handling costs. However, it always shows insufficient protective immunity, mainly due to antigen degradation in the gastrointestinal tract (GIT). Bacillus subtilis spores have been shown to be able to ...

journal_title：Genes

authors： Sun R,Zhang M,Chen H,Wei Y,Ning D

更新日期：2020-11-14 00:00:00

abstract：:MYO6 is known as a genetic cause of autosomal dominant and autosomal recessive inherited hearing loss. In this study, to clarify the frequency and clinical characteristics of hearing loss caused by MYO6 gene mutations, a large-scale genetic analysis of Japanese patients with hearing loss was performed. By means of mas...

journal_title：Genes

authors： Oka SI,Day TF,Nishio SY,Moteki H,Miyagawa M,Morita S,Izumi S,Ikezono T,Abe S,Nakayama J,Hyogo M,Okamoto N,Uehara N,Oshikawa C,Kitajiri SI,Usami SI

更新日期：2020-03-04 00:00:00

abstract：:Xyloglucan endotransglycosylase/hydrolase (XTH) is a cell-wall-modifying enzyme participating in diverse cell morphogenetic processes and adaptation to stress. In this study, 48 XTH genes were identified from two pineapple (Ananas comosus) cultivars ('F153' and 'MD2') and designated Ac(F153)XTH1 to -24 and Ac(MD2)XTH1...

journal_title：Genes

authors： Li Q,Li H,Yin C,Wang X,Jiang Q,Zhang R,Ge F,Chen Y,Yang L

更新日期：2019-07-16 00:00:00

abstract：:Sarcomas are highly aggressive cancers that have a high propensity for metastasis, fail to respond to conventional therapies, and carry a poor 5-year survival rate. This is particularly true for patients with neurofibromatosis type 1 (NF1), in which 8%-13% of affected individuals will develop a malignant peripheral ne...

journal_title：Genes

authors： Moon CI,Tompkins W,Wang Y,Godec A,Zhang X,Pipkorn P,Miller CA,Dehner C,Dahiya S,Hirbe AC

更新日期：2020-05-01 00:00:00

abstract：:Epigenetic alterations at imprinted genes on different chromosomes have been linked to several imprinting disorders (IDs) such as Beckwith-Wiedemann syndrome (BWS) and pseudohypoparathyroidism type 1b (PHP1b). Here, we present a male patient with these two distinct IDs caused by two independent mechanisms-loss of meth...

journal_title：Genes

authors： Choufani S,Ko JM,Lou Y,Shuman C,Fishman L,Weksberg R

更新日期：2021-01-27 00:00:00

abstract：:Increasing evidence suggests that dysregulation of microRNAs (miRNAs) may lead to a variety of diseases. Therefore, identifying disease-related miRNAs is a crucial problem. Currently, many computational approaches have been proposed to predict binary miRNA-disease associations. In this study, in order to predict under...

journal_title：Genes

authors： Zhang X,Yin J,Zhang X

更新日期：2018-03-02 00:00:00

abstract：:A large number of studies have focused on identifying molecular biomarkers, including microRNAs (miRNAs) to aid in the diagnosis and prognosis of the most common subtypes of non-Hodgkin lymphoma (NHL), Diffuse Large B-cell Lymphoma and Follicular Lymphoma. NHL is difficult to diagnose and treat with many cases becomin...

journal_title：Genes

authors： Bradshaw G,Sutherland HG,Haupt LM,Griffiths LR

更新日期：2016-12-17 00:00:00

abstract：:The etiology and reasons underlying the ethnic disparities in systemic sclerosis (SSc) remain unknown. African Americans are disproportionally affected by SSc and yet are underrepresented in research. The aim of this study was to comprehensively investigate the association of DNA methylation levels with SSc in dermal ...

journal_title：Genes

authors： Baker Frost D,da Silveira W,Hazard ES,Atanelishvili I,Wilson RC,Flume J,Day KL,Oates JC,Bogatkevich GS,Feghali-Bostwick C,Hardiman G,Ramos PS

更新日期：2021-01-20 00:00:00

abstract：:The northern sea otter inhabits coastal waters of the northern Pacific Ocean and is the largest member of the Mustelidae family. DNA sequencing methods that utilize microfluidic partitioned and non-partitioned library construction were used to establish the sea otter genome. The final assembly provided 2.426 Gbp of hi...

journal_title：Genes

authors： Jones SJ,Haulena M,Taylor GA,Chan S,Bilobram S,Warren RL,Hammond SA,Mungall KL,Choo C,Kirk H,Pandoh P,Ally A,Dhalla N,Tam AKY,Troussard A,Paulino D,Coope RJN,Mungall AJ,Moore R,Zhao Y,Birol I,Ma Y,Marra M,Jo

更新日期：2017-12-11 00:00:00

abstract：:Salinity is one of the major environment factors that limits the growth of plants and the productivity of crops worldwide. It has been shown that Na+ transporters play a central role in salt tolerance and development of plants. The objective of this study was to identify Na+/H+ antiporter (NHX) genes and investigate t...

journal_title：Genes

authors： Wu GQ,Wang JL,Li SJ

更新日期：2019-05-27 00:00:00

abstract：:More than fifteen genetic diseases, including Huntington's disease, myotonic dystrophy 1, fragile X syndrome and Friedreich ataxia, are caused by the aberrant expansion of a trinucleotide repeat. The mutation is unstable and further expands in specific cells or tissues with time, which can accelerate disease progressi...

journal_title：Genes

authors： Goula AV,Merienne K

更新日期：2013-07-25 00:00:00

abstract：:Amazonian puffing snakes (Spilotes; Colubridae) are snakes widely distributed in the Neotropical region. However, chromosomal data are scarce in this group and, when available, are only limited to karyotype description using conventional staining. In this paper, we focused on the process of karyotype evolution and tre...

journal_title：Genes

authors： Viana PF,Ezaz T,de Bello Cioffi M,Jackson Almeida B,Feldberg E

更新日期：2019-04-09 00:00:00

abstract：:Rice seed is a pivotal reproductive organ that directly determines yield and quality. Long non-coding RNAs (lncRNAs) have been recognized as key regulators in plant development, but the roles of lncRNAs in rice seed development remain unclear. In this study, we performed a paired-end RNA sequencing in samples of rice ...

journal_title：Genes

authors： Zhao J,Ajadi AA,Wang Y,Tong X,Wang H,Tang L,Li Z,Shu Y,Liu X,Li S,Wang S,Liu W,Zhang J

更新日期：2020-02-26 00:00:00

abstract：:Cell size affects almost all biosynthetic processes by controlling the size of organelles and disrupting the nutrient uptake process. Yeast cells must reach a critical size to be able to enter a new cell cycle stage. Abnormal changes in cell size are often observed under pathological conditions such as cancer disease....

journal_title：Genes

authors： Zhao X,Li X,Zhang P,Li C,Feng W,Zhu X,Wei D

更新日期：2020-04-16 00:00:00

abstract：:High-throughput technologies have allowed researchers to obtain genome-wide data from a wide array of experimental model systems. Unfortunately, however, new data generation tends to significantly outpace data re-utilization, and most high throughput datasets are only rarely used in subsequent studies or to generate n...

journal_title：Genes

authors： Halajyan A,Weingart N,Yeahia M,Loza-Coll M

更新日期：2019-06-01 00:00:00

abstract：:As a major infectious disease in chickens, Newcastle disease virus (NDV) causes considerable economic losses in the poultry industry, especially in developing countries where there is limited access to effective vaccination. Therefore, enhancing resistance to the virus in commercial chickens through breeding is a prom...

journal_title：Genes

authors： Zhang J,Kaiser MG,Gallardo RA,Kelly TR,Dekkers JCM,Zhou H,Lamont SJ

更新日期：2020-08-26 00:00:00

abstract：:Circadian clocks in eukaryotes involve both transcriptional-translational feedback loops, post-translational regulation, and metabolic, non-transcriptional oscillations. We recently identified the involvement of circadian oscillations in the intracellular concentrations of magnesium ions (Mg2+i) that were conserved in...

journal_title：Genes

authors： Feord HK,Dear FEG,Obbard DJ,van Ooijen G

更新日期：2019-02-19 00:00:00

abstract：:In this work, we have shown that Novosphingobium tardaugens NBRC 16725 (strain ARI-1), a bacterial strain that was isolated due to its capacity to mineralize the estrogenic endocrine compound 17β-estradiol, is also able to mineralize testosterone, the androgenic endocrine compound. Using in silico analysis, we predict...

journal_title：Genes

authors： Ibero J,Galán B,Díaz E,García JL

更新日期：2019-10-31 00:00:00

abstract：:There is an ongoing worldwide coronavirus disease 2019 (Covid-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At present, confirmatory diagnosis is by reverse transcription polymerase chain reaction (RT-PCR), typically taking several hours and requiring a molecular laboratory to pe...

journal_title：Genes

authors： Wee SK,Sivalingam SP,Yap EPH

更新日期：2020-06-18 00:00:00

abstract：:During the evolution of heteromorphic sex chromosomes, the sex-specific Y chromosome degenerates, while the X chromosome evolves new mechanisms of regulation. Using bioinformatic and experimental approaches, we investigate the expression of the X chromosome in Drosophila melanogaster. We observe nearly complete X chro...

journal_title：Genes

authors： Argyridou E,Parsch J

更新日期：2018-05-04 00:00:00

abstract：:Gruiformes is a group with phylogenetic issues. Recent studies based on mitochondrial and genomic DNA have proposed the existence of a core Gruiformes, consisting of five families: Heliornithidae, Aramidae, Gruidae, Psophiidae and Rallidae. Karyotype studies on these species are still scarce, either by conventional st...

journal_title：Genes

authors： Furo IO,Kretschmer R,O'Brien PCM,Pereira JC,Ferguson-Smith MA,de Oliveira EHC

更新日期：2020-03-13 00:00:00