Abstract:
:We have precisely mapped and sequenced the three 5' exons of the Drosophila melanogaster Gld gene and have identified the start sites for transcription and translation. The first exon is composed of 335 nucleotides and does not contain any putative translation start codons. The second exon is separated from the first exon by 8 kb and contains the Gld translation start codon. The inferred amino acid sequence of the amino terminus contains two unusual features: three tandem repeats of serine-alanine, and a relatively high density of cysteine residues. P element-mediated transformation experiments demonstrated that a 17.5-kb genomic fragment contains the functional and regulatory components of the Gld gene.
journal_name
Geneticsjournal_title
Geneticsauthors
Whetten R,Organ E,Krasney P,Cox-Foster D,Cavener Dsubject
Has Abstractpub_date
1988-10-01 00:00:00pages
475-84issue
2eissn
0016-6731issn
1943-2631journal_volume
120pub_type
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