Emerging and innovative approaches for wound healing and skin regeneration: Current status and advances.

abstract：:Alginate/aminopropyl-silicate/alginate (Alg/AS/Alg) membrane was prepared on Ca-alginate gel beads by a sol-gel process. The membrane has identical to Si-O-Si identical to bonds as well as electrostatic bonds between amino groups of AS and carboxyl groups of alginate. Permeability and stability were investigated for t...

journal_title：Biomaterials

authors： Sakai S,Ono T,Ijima H,Kawakami K

更新日期：2002-11-01 00:00:00

abstract：:Isostatic compression has rarely been used to load calcium-phosphate biomaterials with therapeutic agents. This report, concerning four processes associating vancomycin, compares isostatic compression with wet granulation, a classical method. In the wet granulation study, vancomycin was associated with biphasic calciu...

journal_title：Biomaterials

authors： Gautier H,Merle C,Auget JL,Daculsi G

更新日期：2000-02-01 00:00:00

abstract：:Tumor-homing cytotoxic stem cell (SC) therapy is a promising new approach for treating the incurable brain cancer glioblastoma (GBM). However, problems of retaining cytotoxic SCs within the post-surgical GBM resection cavity are likely to significantly limit the clinical utility of this strategy. Here, we describe a n...

journal_title：Biomaterials

authors： Bagó JR,Pegna GJ,Okolie O,Hingtgen SD

更新日期：2016-04-01 00:00:00

abstract：:The torque-tension characteristics of standard, conical and flanged external fixator pins and a cortical screw were compared using a commercially available testing apparatus. The flanged pin and the screw were similar in behaviour, and converted torque into tension more efficiently than conical and standard external f...

journal_title：Biomaterials

authors： Oni OO,Batchelor JS

更新日期：1995-11-01 00:00:00

abstract：:Cerium oxide nanoparticles (nanoceria) are promising materials for intracellular oxygen free radical scavenging providing a potential therapy for reactive oxygen species (ROS)-mediated inflammatory processes. In this study rhombohedral-shaped nanoceria were synthesized by flame spray pyrolysis with tuneable particle d...

journal_title：Biomaterials

authors： Lord MS,Jung M,Teoh WY,Gunawan C,Vassie JA,Amal R,Whitelock JM

更新日期：2012-11-01 00:00:00

abstract：:The role of albumin in the mineralisation process of commercial hydroxyapatite (HAp) and synthesised biphasic (HAp-tricalcium phosphate) ceramics in a bufferless simulated inorganic plasma (HBSS) was investigated by conventional in vitro tests and static and dynamic wettability measurements. Albumin was either pre-ads...

journal_title：Biomaterials

authors： Marques PA,Serro AP,Saramago BJ,Fernandes AC,Magalhães MC,Correia RN

更新日期：2003-02-01 00:00:00

abstract：:This is the first report on a series of studies of the crystallinity of bone tissues. The measurements were done at the microfocused diffraction beamline at ERSF (European Synchrotron Radiation Facility) as a feasibility test on various aspects on microdiffraction analysis. Beside the crystal structure, crystallite si...

journal_title：Biomaterials

authors： Rindby A,Voglis P,Engström P

更新日期：1998-11-01 00:00:00

abstract：:Animal models have been used extensively to investigate the biology of fracture healing and spinal fusion. The goal of each spinal fusion model is to try and reproduce the correct sequence of events during osseous healing in humans. Animal models allow us the capability of dialing in fusion rates and fusion parameters...

journal_title：Biomaterials

authors： Khan SN,Lane JM

更新日期：2004-04-01 00:00:00

abstract：:A range of poly(alkyl methacrylate)s in the range C5 to C13 with varying degrees of crosslinking, have been studied with respect to stress-strain behaviour. Where the extensions to break were sufficiently high, stress-strain properties conformed well to the statistical theory of rubber elasticity, the Mooney/Rivlin C2...

journal_title：Biomaterials

authors： Davy KW,Braden M

更新日期：1987-09-01 00:00:00

abstract：:The thermally responsive cholesteryl end-capped poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) and cholesteryl grafted poly[N-isopropylacrylamide-co-N-(hydroxymethyl) acrylamide] amphiphilic polymers were synthesized and utilized to encapsulate cyclosporin A (CyA) and indomethacin (IND) within core-shell nanopa...

journal_title：Biomaterials

authors： Chaw CS,Chooi KW,Liu XM,Tan CW,Wang L,Yang YY

更新日期：2004-08-01 00:00:00

abstract：:Cells form hollow, spheroidal structures during the development of many tissues, including the ocular lens, inner ear, and many glands. Therefore, techniques for in vitro formation of hollow spheroids are valued for studying developmental and disease processes. Current in vitro methods require cells to self-organize i...

journal_title：Biomaterials

authors： Wang E,Wang D,Geng A,Seo R,Gong X

更新日期：2017-10-01 00:00:00

abstract：:The purpose of this article is to examine the effects of tricaprin on the physical characteristics and in vitro release of etoposide from poly (lactic-co-glycolic acid) microspheres. The microspheres were synthesized through the use of a single-emulsion solvent-extraction procedure. Samples from each batch of microsph...

journal_title：Biomaterials

authors： Schaefer MJ,Singh J

更新日期：2002-08-01 00:00:00

abstract：:Biological surface engineering using synthetic biological materials has a great potential for advances in our understanding of complex biological phenomena. We developed a simple system to engineer biologically relevant surfaces using a combination of self-assembling oligopeptide monolayers and microcontact printing (...

journal_title：Biomaterials

authors： Zhang S,Yan L,Altman M,Lässle M,Nugent H,Frankel F,Lauffenburger DA,Whitesides GM,Rich A

更新日期：1999-07-01 00:00:00

abstract：:Retinal pigment epithelial (RPE) cellular morphology and function are vital to the health of the retina. In age-related macular degeneration, RPE dysfunction and changes in Bruch's membrane occur. Thus, a potential cure is a dual-layer biomimetic transplant consisting of a layer of healthy RPE cells cultured on a supp...

journal_title：Biomaterials

authors： Lee CJ,Fishman HA,Bent SF

更新日期：2007-04-01 00:00:00

abstract：:Adhesion of tissue cells is a prerequisite for their growth and differentiation but prevents also apoptosis. Here the layer-by-layer technique (LbL) was used to design multilayer structures of poly(ethylene imine) (PEI) and heparin (HEP) on glass as model biomaterial to control the adhesion of primary human dermal fib...

journal_title：Biomaterials

authors： Niepel MS,Peschel D,Sisquella X,Planell JA,Groth T

更新日期：2009-10-01 00:00:00

abstract：:A graft copolymer having poly(L-lysine) (PLL) as the backbone and monomethoxy poly(ethylene glycol) (MPEG) as pendent chains was synthesized. This polycationic copolymer was used to form microcapsules with sodium alginate, a polyanion. Microcapsules and model surfaces formed with PLL-graft-MPEG demonstrated reduced pr...

journal_title：Biomaterials

authors： Sawhney AS,Hubbell JA

更新日期：1992-01-01 00:00:00

abstract：:Plaque-induced lesions can produce peri-implant bone loss with ultimate implant loss. Although the peri-implant tissues seem to be more resistant than the periodontal ones to plaque and calculus, they can produce a more extensive spread of the infection to the deeper tissues around implants. The case of a 45-year-old ...

journal_title：Biomaterials

authors： Piattelli A,Cosci F,Scarano A,Trisi P

更新日期：1995-08-01 00:00:00

abstract：:Implantation of synthetic material, including vascular grafts, pacemakers, etc. results in the foreign body reaction and the formation of multinucleated giant cells (MGCs) at the exterior surface of the implant. Despite the long-standing premise that fusion of mononucleated macrophages results in the formation of MGCs...

journal_title：Biomaterials

authors： Faust JJ,Christenson W,Doudrick K,Ros R,Ugarova TP

更新日期：2017-06-01 00:00:00

abstract：:The degradation of poly[bis(glycine ethyl ester)phosphazene] in aqueous media was studied by following the appearance of some of its expected by-products in solution. Disc-shaped polymer slabs of 12 mm diameter and 1.2 mm thickness were prepared by compression moulding, followed by incubation in aqueous media under ca...

journal_title：Biomaterials

authors： Ruiz EM,Ramírez CA,Aponte MA,Barbosa-Cánovas GV

更新日期：1993-06-01 00:00:00

abstract：:To prevent bone metastasis, we developed polyethylene glycol (PEG)-conjugated aspartic acid (Asp)-modified liposomes (PEG-Asp-Lipo) as a bone-targeting carrier of paclitaxel (PTX) by using Asp-modified 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE-Asp). The affinity of Asp-modified liposomes to hydroxyapatite...

journal_title：Biomaterials

authors： Yamashita S,Katsumi H,Hibino N,Isobe Y,Yagi Y,Tanaka Y,Yamada S,Naito C,Yamamoto A

更新日期：2018-02-01 00:00:00

abstract：:We design a class of imprinted hybrid microgels that can optically monitor glucose levels with high sensitivity and selectivity in complex media at physiological pH, acting like a "glucose-indicator". Such imprinted hybrid microgels were made of Ag nanoparticles (NPs) in situ immobilized in molecularly imprinted gluco...

journal_title：Biomaterials

authors： Wu W,Shen J,Li Y,Zhu H,Banerjee P,Zhou S

更新日期：2012-10-01 00:00:00

abstract：:To develop artificial materials for prolonged use in the vascular system, the complicated process of surface-induced thrombosis needs to be better understood. Steroidal hormones have a profound role in thrombosis and haemostasis, although adequate studies are not available to demonstrate their part in the thromboembol...

journal_title：Biomaterials

authors： Sharma CP,Chandy T

更新日期：1989-11-01 00:00:00

abstract：:The introduction of metal-on-metal total disc replacements motivated studies to evaluate the effects of cobalt-chromium (CoCr) nanoparticles on cells of the dura mater. Porcine fibroblasts and epithelial cells isolated from the dura mater were cultured with clinically-relevant CoCr nanoparticles and the ions, generate...

journal_title：Biomaterials

authors： Behl B,Papageorgiou I,Brown C,Hall R,Tipper JL,Fisher J,Ingham E

更新日期：2013-05-01 00:00:00

abstract：:Silicone elastomers have been used as implants in orthopaedics for replacements of small joints such as the metacarpophalangeal joint. A series of experiments was conducted an axially tensioned silicone elastomer tendon spacer samples to determine whether there is a relationship between stress in the material and imag...

journal_title：Biomaterials

authors： Abel EW,Wheeler KI,Chudek JA,Hunter G,Som FM

更新日期：1998-01-01 00:00:00

abstract：:We present here an easy method to modify the surface chemistry of polymeric microcapsules of perfluorooctyl bromide used as ultrasound contrast agents (UCAs). Capsules were obtained by a solvent emulsification-evaporation process with phospholipids incorporated in the organic phase before emulsification. Several phosp...

journal_title：Biomaterials

authors： Díaz-López R,Tsapis N,Libong D,Chaminade P,Connan C,Chehimi MM,Berti R,Taulier N,Urbach W,Nicolas V,Fattal E

更新日期：2009-03-01 00:00:00

abstract：:This article reviews the controlled release of biologically active agents by the erosion or chemical degradation of a polymer matrix into which the agent is incorporated. Chemically bound active agents and work on steroid release from cholesterol implants are not covered. The mechanisms of polymer erosion discussed ar...

journal_title：Biomaterials

authors： Heller J

更新日期：1980-01-01 00:00:00

abstract：:Resorbable calcium phosphate (CaP) biomaterials have demonstrated considerable efficacy in bone reconstructive surgery. Furthermore, bisphosphonates (BPs) are well known anti-resorptive agents largely used in clinical treatments for osteoporosis. An injectable BP-combined CaP matrix has been developed in order to biol...

journal_title：Biomaterials

authors： Verron E,Gauthier O,Janvier P,Pilet P,Lesoeur J,Bujoli B,Guicheux J,Bouler JM

更新日期：2010-10-01 00:00:00

abstract：:The aim of the present study was to test the hypothesis that oligonucleotides can be used for anchorage and slow release of osteogenic growth factors such as BMP to enhance the osteogenic activity of a titanium implant surface. Strands of 60-mer non-coding DNA oligonucleotides (ODN) were bound to an acid-etched sandbl...

journal_title：Biomaterials

authors： Schliephake H,Bötel C,Förster A,Schwenzer B,Reichert J,Scharnweber D

更新日期：2012-02-01 00:00:00

abstract：:Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was loaded with doxorubicin (DOX) through hydrazone, an acid-responsive linker, and was functionalized with angiopep-2, a specific ligand of lo...

journal_title：Biomaterials

authors： Ruan S,Yuan M,Zhang L,Hu G,Chen J,Cun X,Zhang Q,Yang Y,He Q,Gao H

更新日期：2015-01-01 00:00:00

abstract：:The purpose of the present work was to examine the effect of different Ti-6Al-4V surface treatments on osteoblasts behaviour. Previous work in this laboratory has demonstrated that an ageing treatment reduces metal ion release from this alloy compared to standard passivation procedures. In this study. human osteosarco...

journal_title：Biomaterials

authors： Ku CH,Pioletti DP,Browne M,Gregson PJ

更新日期：2002-03-01 00:00:00