Abstract:
:This article reviews the controlled release of biologically active agents by the erosion or chemical degradation of a polymer matrix into which the agent is incorporated. Chemically bound active agents and work on steroid release from cholesterol implants are not covered. The mechanisms of polymer erosion discussed are: cross-linked scission; hydrolysis, ionization or protonation of pendant groups; backbone cleavage. Drug release studies are dealt with under each of these headings.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Heller Jdoi
10.1016/0142-9612(80)90060-5subject
Has Abstractpub_date
1980-01-01 00:00:00pages
51-7issue
1eissn
0142-9612issn
1878-5905pii
0142-9612(80)90060-5journal_volume
1pub_type
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