The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction.

abstract：:Peri-implant bone formation depends on the ability of mesenchymal cells to colonize the implant surface and differentiate into osteoblasts. Human mesenchymal stem cells (HMSCs) undergo osteoblastic differentiation on microstructured titanium (Ti) surfaces in the absence of exogenous factors, but the mechanisms are unk...

journal_title：Biomaterials

authors： Olivares-Navarrete R,Hyzy SL,Park JH,Dunn GR,Haithcock DA,Wasilewski CE,Boyan BD,Schwartz Z

更新日期：2011-09-01 00:00:00

abstract：:Efficient delivery of small interfering RNA (siRNA) or small hairpin RNA (shRNA) is a critical concern in RNA interference (RNAi) studies. In the present study, we evaluated biodegradable poly(beta-amino ester) (PAE) carrier composed of low molecular weight polyethylenimine and poly(ethylene glycol) for si/shRNA deliv...

journal_title：Biomaterials

authors： Jere D,Xu CX,Arote R,Yun CH,Cho MH,Cho CS

更新日期：2008-06-01 00:00:00

abstract：:The formation of bone tissue in pores, and around, a block made of partially dehydroxylated porous hydroxyapatite ceramic and implanted into a rat's femur using X-ray diffraction (XRD), infrared spectroscopy (IRS) and histological methods were investigated. Structural characteristics and composition of new bone tissue...

journal_title：Biomaterials

authors： Zyman Z,Ivanov I,Glushko V,Dedukh N,Malyshkina S

更新日期：1998-07-01 00:00:00

abstract：:Chitosan coated porous titanium alloy implant (CTI) is demonstrated a promising approach to improve osseointegration capacity of pure porous titanium alloy implant (TI). Since chitosan has been demonstrated to exhibit antioxidant activity, we propose CTI may ameliorate the ROS overproduction, thus reverse the poor oss...

journal_title：Biomaterials

authors： Li X,Ma XY,Feng YF,Ma ZS,Wang J,Ma TC,Qi W,Lei W,Wang L

更新日期：2015-01-01 00:00:00

abstract：:The aim of this in vitro study was to evaluate the antimicrobial activity, the substantivity, and surface effects of the inclusion compound tetracycline: beta-cyclodextrin on bovine roots. The antimicrobial activity was assessed by dentine slabs which had been immersed in the inclusion complex in concentrations 8.0%, ...

journal_title：Biomaterials

authors： Pataro AL,Franco CF,Santos VR,Cortés ME,Sinisterra RD

更新日期：2003-03-01 00:00:00

abstract：:Recent advances in efficient microRNA (miRNA) delivery techniques using brain-targeted nanoparticles offer critical information for understanding the functional role of miRNAs in vivo, and for supporting targeted gene therapy in terms of treating miRNA-associated neurological diseases. Here, we report the rabies virus...

journal_title：Biomaterials

authors： Hwang DW,Son S,Jang J,Youn H,Lee S,Lee D,Lee YS,Jeong JM,Kim WJ,Lee DS

更新日期：2011-07-01 00:00:00

abstract：:Astroglial cell survival and ion channel activity are relevant molecular targets for the mechanistic study of neural cell interactions with biomaterials and/or electronic interfaces. Astrogliosis is the most typical reaction to in vivo brain implants and needs to be avoided by developing biomaterials that preserve ast...

journal_title：Biomaterials

authors： Benfenati V,Toffanin S,Capelli R,Camassa LM,Ferroni S,Kaplan DL,Omenetto FG,Muccini M,Zamboni R

更新日期：2010-11-01 00:00:00

abstract：:Acetaminophen (APAP) is the most widely used analgesic and its overdose, intentional or unintentional, is known to cause massive oxidative stress and liver tissue damages characterized by hepatocellular apoptosis and hemorrhagic necrosis, leading to acute liver failure (ALF). There has been great interest in the use o...

journal_title：Biomaterials

authors： Ko E,Jeong D,Kim J,Park S,Khang G,Lee D

更新日期：2014-04-01 00:00:00

abstract：:Platelet-derived growth factor BB (PDGF-BB) was an important inductive factor during wound healing, but the lack of efficient delivery system limited its clinical application. Here, a peptide of seven amino acids was firstly utilized to engineer PDGF-BB to construct a collagen-targeting system. This peptide functioned...

journal_title：Biomaterials

authors： Lin H,Chen B,Sun W,Zhao W,Zhao Y,Dai J

更新日期：2006-11-01 00:00:00

abstract：:Engineering extracellular matrices that utilize the body's natural healing capacity enable the progression of regenerative therapies. Fibrin, widely used as a surgical sealant, is one such matrix that may be augmented by the addition of protein factors to promote cell infiltration and differentiation. The thrombin-cat...

journal_title：Biomaterials

authors： Soon AS,Stabenfeldt SE,Brown WE,Barker TH

更新日期：2010-03-01 00:00:00

abstract：:ROCK activity increases due to ECM rigidity in the tumor microenvironment and promotes a malignant phenotype via actomyosin contractility. Invasive migration is facilitated by actin-rich adhesive protrusions known as invadopodia that degrade the ECM. Invadopodia activity is dependent on matrix rigidity and contractile...

journal_title：Biomaterials

authors： Jerrell RJ,Parekh A

更新日期：2016-04-01 00:00:00

abstract：:The purpose of this study was to investigate the chemical influence of chemo-mechanical caries removal (CMCR) on surface topography of dental ceramic materials. Thirty samples of three different types of ceramics (Vita Omega, Vita Alpha, and Procera AllTitan) were manufactured and used. With an optical profilometer, d...

journal_title：Biomaterials

authors： Arvidsson A,Milleding P,Wennerberg A

更新日期：2002-10-01 00:00:00

abstract：:An appropriate method to bind extracellular matrix (ECM) proteins and growth factors using advanced protein engineering techniques has the potential to enhance cell proliferation and differentiation for tissue regeneration and repair. In this study we developed a method to co-immobilize non-covalently an ECM protein t...

journal_title：Biomaterials

authors： Assal Y,Mie M,Kobatake E

更新日期：2013-04-01 00:00:00

abstract：:Characterization of complex adsorbed protein films is a critical aspect of biomaterials science, particularly in understanding the in vivo response to biomaterials. The surface analysis techniques electron spectroscopy for chemical analysis (ESCA) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) are parti...

journal_title：Biomaterials

authors： Wagner MS,Horbett TA,Castner DG

更新日期：2003-05-01 00:00:00

abstract：:Inherent neuronal and circulating progenitor cells play important roles in facilitating neuronal and functional recovery post stroke. However, this endogenous repair process is rather limited, primarily due to unfavorable conditions in the infarcted brain involving reactive oxygen species (ROS)-mediated oxidative stre...

journal_title：Biomaterials

authors： Petro M,Jaffer H,Yang J,Kabu S,Morris VB,Labhasetwar V

更新日期：2016-03-01 00:00:00

abstract：:In this study, acrylamide-maleic acid hydrogels containing different amounts of maleic acid have been prepared by irradiating with gamma radiation. They have been used in experiments on bovine serum albumin (BSA) adsorption. Acrylamide-maleic acid hydrogel containing 60 mg of maleic acid and irradiated at 5.20 kGy has...

journal_title：Biomaterials

authors： Saraydin D,Karadağ E,Oztop HN,Güven O

更新日期：1994-09-01 00:00:00

abstract：:The aim of this study was to follow the in vivo biodegradation as well as to appreciate the brain tissue response to poly(methylidene malonate 2.1.2) (PMM 2.1.2)-based microspheres implanted into the rat brain. Ninety-three adult Sprague-Dawley female rats were engaged in the study in which 54 underwent stereotactic i...

journal_title：Biomaterials

authors： Fournier E,Passirani C,Colin N,Sagodira S,Menei P,Benoit JP,Montero-Menei CN

更新日期：2006-10-01 00:00:00

abstract：:Palladium additions to a dispersed phase high-copper amalgam have been shown recently to suppress markedly the eta' (Cu6Sn5) concentration and decrease creep. A detailed study of the dental and 24 h creep for Pd containing high-copper amalgams and six commercial controls as a function of applied temperature and stress...

journal_title：Biomaterials

authors： Greener EH,Chung KH,Lin JH

更新日期：1988-05-01 00:00:00

abstract：:This study was designed to examine the adhesion, proliferation, and morphology of chondrocytes on new scaffolds; and to examine these cells histologically for the ability of the chondrocytes to maintain chondrogenic properties after subcutaneous implantation into nude mice. Both 75:25 poly (L-lactide-co-epsilon-caprol...

journal_title：Biomaterials

authors： Honda M,Morikawa N,Hata K,Yada T,Morita S,Ueda M,Kimata K

更新日期：2003-09-01 00:00:00

abstract：:We investigated the feasibility and efficacy of target thrombolysis with recombinant tissue plasminogen activator (rtPA) covalently bound to magnetic nanoparticle (MNP) and retained to the target site in vivo by an external magnet. Polyacrylic acid-coated magnetite (PAA-MNP, 246 nm) was synthesized and characterized; ...

journal_title：Biomaterials

authors： Ma YH,Wu SY,Wu T,Chang YJ,Hua MY,Chen JP

更新日期：2009-07-01 00:00:00

abstract：:The incorporation of growth factors into new methylidene malonate 2.1.2-based biocompatible polymeric blends of oligomers and polymers to improve their stability and controlled release was investigated. Five growth factors were used in this study: FGF2, PDGF, TGF-beta, NGF and GM-CSF. Formulation in poly(methylidene m...

journal_title：Biomaterials

authors： Désiré L,Mysiakine E,Bonnafous D,Couvreur P,Sagodira S,Breton P,Fattal E

更新日期：2006-04-01 00:00:00

abstract：:The use of non-viral nanoparticulate systems for the delivery of therapeutic agents is receiving considerable attention for medical and pharmaceutical applications. This increasing interest results from the fact that these systems can be designed to meet specific physicochemical requirements, and they display low toxi...

journal_title：Biomaterials

authors： Chellat F,Merhi Y,Moreau A,Yahia L

更新日期：2005-12-01 00:00:00

abstract：:The calcination and natural sintering of calcium deficient hydroxyapatite powders Ca(10-x)(PO4)(6-x)(HPO4)x(OH)(2-x) (with 0 < or = x < or = 1) were studied. For temperature below 700 degrees C, particle coalescence occurs without densification. The particle coalescence is associated with a reduction of the specific s...

journal_title：Biomaterials

authors： Raynaud S,Champion E,Bernache-Assollant D

更新日期：2002-02-01 00:00:00

abstract：:We design a class of imprinted hybrid microgels that can optically monitor glucose levels with high sensitivity and selectivity in complex media at physiological pH, acting like a "glucose-indicator". Such imprinted hybrid microgels were made of Ag nanoparticles (NPs) in situ immobilized in molecularly imprinted gluco...

journal_title：Biomaterials

authors： Wu W,Shen J,Li Y,Zhu H,Banerjee P,Zhou S

更新日期：2012-10-01 00:00:00

abstract：:Gd3+-based contrast agents monopolize in the clinical MR imaging-based diagnosis of hepatic tumors, however, the inherent toxicity by the released Gd3+-ions triggered an urgent demand for safer alternatives. Here, we demonstrate hollow manganese silicate nanoparticles (HMS), which exert burst-release of Mn2+-ions by s...

journal_title：Biomaterials

authors： Kim JG,Jang MS,Kumari N,Choi JK,Im GH,Kwon T,Lee JH,Lee WJ,Lee IS

更新日期：2020-02-01 00:00:00

abstract：:The functionalization of polytetrafluoroethylene (PTFE) for human thrombomodulin (hTM) binding has been achieved by CO2 plasma activation and subsequent vapour phase graft polymerization of acrylic acid (AA). The PTFE surfaces after CO2 plasma treatment, AA grafting and hTM immobilization were characterized by attenua...

journal_title：Biomaterials

authors： Vasilets VN,Hermel G,König U,Werner C,Müller M,Simon F,Grundke K,Ikada Y,Jacobasch HJ

更新日期：1997-09-01 00:00:00

abstract：:Electrically conducting polymers hold promise for developing advanced neuroprostheses, bionic systems and neural repair devices. Among them, poly(3, 4-ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) exhibits superior physicochemical properties but biocompatibility issues have limited its use. We d...

journal_title：Biomaterials

authors： Collazos-Castro JE,Polo JL,Hernández-Labrado GR,Padial-Cañete V,García-Rama C

更新日期：2010-12-01 00:00:00

abstract：:To fully understand biological behavior in vitro often dictates that oxygen be reported at either a local or a cellular level. Oxygen sensors based on the luminescent quenching of a specific form of electrospun fiber were developed for measurement of both gaseous and dissolved oxygen concentrations. Electrospinning wa...

journal_title：Biomaterials

authors： Xue R,Nelson MT,Teixeira SA,Viapiano MS,Lannutti JJ

更新日期：2016-01-01 00:00:00

abstract：:Heparin-conjugated electrospun poly(ε-caprolactone) (PCL)/gelatin scaffolds were developed to provide controlled release of platelet-derived growth factor-BB (PDGF-BB) and allow prolonged bioactivity of this molecule. A mixture of PCL and gelatin was electrospun into three different morphologies. Next, heparin molecul...

journal_title：Biomaterials

authors： Lee J,Yoo JJ,Atala A,Lee SJ

更新日期：2012-10-01 00:00:00

abstract：:In contractile tissues such as myocardium, functional properties are directly related to the cellular orientation and elongation. Thus, tissue engineering of functional cardiac patches critically depends on our understanding of the interaction between multiple guidance cues such as topographical, adhesive or electrica...

journal_title：Biomaterials

authors： Au HT,Cheng I,Chowdhury MF,Radisic M

更新日期：2007-10-01 00:00:00