Poly(beta-amino ester) as a carrier for si/shRNA delivery in lung cancer cells.

abstract：:The role of albumin in the mineralisation process of commercial hydroxyapatite (HAp) and synthesised biphasic (HAp-tricalcium phosphate) ceramics in a bufferless simulated inorganic plasma (HBSS) was investigated by conventional in vitro tests and static and dynamic wettability measurements. Albumin was either pre-ads...

journal_title：Biomaterials

authors： Marques PA,Serro AP,Saramago BJ,Fernandes AC,Magalhães MC,Correia RN

更新日期：2003-02-01 00:00:00

abstract：:We have previously shown that the high-affinity streptavidin (SA)-biotin interaction enhanced the initial integrin-mediated adhesion of biotinylated endothelial cells to SA-coated surface by serving as an extrinsic bond to stabilize and enhance the intrinsic fibronectin-integrin binding between the cell and surface. H...

journal_title：Biomaterials

authors： Chan BP,Chilkoti A,Reichert WM,Truskey GA

更新日期：2003-02-01 00:00:00

abstract：:We present here an easy method to modify the surface chemistry of polymeric microcapsules of perfluorooctyl bromide used as ultrasound contrast agents (UCAs). Capsules were obtained by a solvent emulsification-evaporation process with phospholipids incorporated in the organic phase before emulsification. Several phosp...

journal_title：Biomaterials

authors： Díaz-López R,Tsapis N,Libong D,Chaminade P,Connan C,Chehimi MM,Berti R,Taulier N,Urbach W,Nicolas V,Fattal E

更新日期：2009-03-01 00:00:00

abstract：:The degree of metal ion dissolution from Ti-6Al-4V alloy hip replacement stems subjected to various mechanical and chemical surface pretreatments was analysed in vitro. High-dissolution rates were observed for nitric acid passivated samples that had been mechanically surface treated to increase the implant surface are...

journal_title：Biomaterials

authors： Browne M,Gregson PJ

更新日期：2000-02-01 00:00:00

abstract：:Polydimethacrylate resins were prepared by photopolymerization of Bis-GMA, TEGDMA, UDMA or Bis-EMA (4) monomer, initiated by camphoroquinone/N,N-dimethylaminoethyl methacrylate system. The study of physical properties of these resins showed that TEGDMA seems to create the most dense polymer network, which however is t...

journal_title：Biomaterials

authors： Sideridou I,Tserki V,Papanastasiou G

更新日期：2003-02-01 00:00:00

abstract：:Stem cell transplantation is a promising therapeutic strategy for acute or chronic ischemic cardiomyopathy. A major limitation to efficacy in cell transplantation is the low efficiency of retention and engraftment, due at least in part to significant early "wash-out" of cells from coronary blood flow and heart contrac...

journal_title：Biomaterials

authors： Vandergriff AC,Hensley TM,Henry ET,Shen D,Anthony S,Zhang J,Cheng K

更新日期：2014-10-01 00:00:00

abstract：:Herein we describe a bio-inspired, affinity binding alginate-sulfate scaffold, designed for the presentation and sustained release of transforming growth factor beta 1 (TGF-β1), and examine its effects on the chondrogenesis of human mesenchymal stem cells (hMSCs). When attached to matrix via affinity interactions with...

journal_title：Biomaterials

authors： Re'em T,Kaminer-Israeli Y,Ruvinov E,Cohen S

更新日期：2012-01-01 00:00:00

abstract：:Suture materials may interact with immune competent cells and thereby affect localized immunity. Macrophages are central to the inflammatory response and coordinate wound healing. They are also involved in the clearance of foreign material, bacteria and malignant cells. We studied the influence of soluble factors asso...

journal_title：Biomaterials

authors： Uff CR,Scott AD,Pockley AG,Phillips RK

更新日期：1995-03-01 00:00:00

abstract：:Bone marrow is the primary hematopoietic organ, which is involved in multiple malignant diseases including acute and chronic leukemia, multiple myeloma, myelodysplastic syndromes, and bone metastases from solid tumors. These malignancies affect normal homeostasis and reshape the bone marrow microenvironment. There are...

journal_title：Biomaterials

authors： Mu CF,Shen J,Liang J,Zheng HS,Xiong Y,Wei YH,Li F

更新日期：2018-02-01 00:00:00

abstract：:Particle-associated periprosthetic osteolysis remains a major issue in joint replacement. Ongoing bone loss resulting from wear particle-induced inflammation is accompanied by continued attempts at bone repair. Previously we showed that mesenchymal stem cells (MSCs) are recruited systemically to bone exposed to contin...

journal_title：Biomaterials

authors： Gibon E,Yao Z,Rao AJ,Zwingenberger S,Batke B,Valladares R,Smith RL,Biswal S,Gambhir SS,Goodman SB

更新日期：2012-05-01 00:00:00

abstract：:Injectable, biodegradable scaffolds are important biomaterials for tissue engineering and drug delivery. Hydrogels derived from natural polysaccharides are ideal scaffolds as they resemble the extracellular matrices of tissues comprised of various glycosaminoglycans (GAGs). Here, we report a new class of biocompatible...

journal_title：Biomaterials

authors： Tan H,Chu CR,Payne KA,Marra KG

更新日期：2009-05-01 00:00:00

abstract：:Bioactive glass granules were implanted in the tibiae of rabbits in order to determine the pathway of the silicon released from bioactive glass in vivo. We traced and quantified the silicon released by obtaining 24-h urine samples and blood samples for up to 7 months after implantation. Bone tissue as well as the foll...

journal_title：Biomaterials

authors： Lai W,Garino J,Ducheyne P

更新日期：2002-01-01 00:00:00

abstract：:Micro-computed tomography (micro-CT) is an emerging imaging modality, due to the low cost of the imagers as well as their efficiency in establishing high-resolution (1-100 μm) three-dimensional images of small laboratory animals and facilitating rapid, structural and functional in vivo visualization. However use of a ...

journal_title：Biomaterials

authors： Li X,Anton N,Zuber G,Zhao M,Messaddeq N,Hallouard F,Fessi H,Vandamme TF

更新日期：2013-01-01 00:00:00

abstract：:The histology and cytology of the tissue response to intra-articular insertion of particles of acrylic bone cement containing barium sulphate has been studied in the guinea pig knee joint. Following insertion of the acrylic, fibrinous debris admixed with particles became adherent to the synovial membrane. Cell prolife...

journal_title：Biomaterials

authors： Meachim G,Brooke G

更新日期：1984-03-01 00:00:00

abstract：:Methyl methacrylate (MMA) is a volatile liquid widely used in the manufacture of acrylic polymers. In modern dentistry, MMA is the mainstream material in denture bases. MMA has been implicated as primary irritant and sensitizer, which can cause allergic eczematous reaction on the oral mucosa as well as skin. To date, ...

journal_title：Biomaterials

authors： Yang HW,Chou LS,Chou MY,Chang YC

更新日期：2003-08-01 00:00:00

abstract：:Poly(ether-ether-ketone) (PEEK) has been used as a load bearing orthopaedic implant material with clinical success. All of the orthopaedic applications contain stress concentrations (notches) in their design; however, little work has been done to examine the fatigue behavior of PEEK in the presence of a notch. This wo...

journal_title：Biomaterials

authors： Sobieraj MC,Murphy JE,Brinkman JG,Kurtz SM,Rimnac CM

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:To analyze the biocompatibility of multifilament polyester (PET) meshes used for the implantation of auditory brainstem implants in a standardized Wistar rat model (n=29). METHODS:The physical properties of the meshes were examined during surgery. Using a modified plastic embedding, the local tissue reactio...

journal_title：Biomaterials

authors： Quester R,Hermanns B,Klosterhalfen B,Schröder R,Klug N

更新日期：2003-02-01 00:00:00

abstract：:The ultra-short pulse microwave could excite to the strong thermoacoustic (TA) shock wave and deeply penetrate in the biological tissues. Based on this, we developed a novel deep-seated tumor therapy modality with mitochondria-targeting single wall carbon nanotubes (SWNTs) as microwave absorbing agents, which act effi...

journal_title：Biomaterials

authors： Wen L,Ding W,Yang S,Xing D

更新日期：2016-01-01 00:00:00

abstract：:The development of multifunctional nanocarrier with each unit functioning at the correct time and location is a challenge for clinical applications. With this in mind, a type of intelligent mesoporous silica nanocarrier (PGFMSN) is proposed for matrix metalloprotease 2 (MMP 2)-triggered tumor targeting and release by ...

journal_title：Biomaterials

authors： Zou Z,He X,He D,Wang K,Qing Z,Yang X,Wen L,Xiong J,Li L,Cai L

更新日期：2015-07-01 00:00:00

abstract：:The anterior cruciate ligament (ACL) is the most commonly injured intra-articular ligament of the knee, and limitations in existing reconstruction grafts have prompted an interest in tissue engineered solutions. Previously, we reported on a tissue-engineered ACL scaffold fabricated using a novel, three-dimensional bra...

journal_title：Biomaterials

authors： Lu HH,Cooper JA Jr,Manuel S,Freeman JW,Attawia MA,Ko FK,Laurencin CT

更新日期：2005-08-01 00:00:00

abstract：:The coupling of specific antibodies to imaging agents often improves imaging specificity. However, free amine groups designed for the coupling can cause nonspecific binding of the imaging agents. We report here development of a nanocarrier, MnMEIO-silane-NH2-mPEG nanoparticles (NPs), consisting of a manganese-doped ir...

journal_title：Biomaterials

authors： Wu SC,Lin KL,Wang TP,Tzou SC,Singh G,Chen MH,Cheng TL,Chen CY,Liu GC,Lee TW,Hu SH,Wang YM

更新日期：2013-05-01 00:00:00

abstract：:Nitric oxide is a cell signaling molecule that can be a potent inducer of cell death in cancers at elevated concentrations. However, NO is also toxic to normal tissues and chronic exposure at low levels can induce tumor growth. We have designed a polymeric carrier system to deliver nitric oxide locoregionally to tumor...

journal_title：Biomaterials

authors： Duan S,Cai S,Yang Q,Forrest ML

更新日期：2012-04-01 00:00:00

abstract：:DNA vaccine is a milestone in contemporary vaccine development. It has considerably offset many shortcomings in conventional vaccines. Although DNA vaccines applied through 'traditional' high-pressure gene guns generally elicit high titers of protective immunity, such a practice however requires enormous investment in...

journal_title：Biomaterials

authors： Huang HN,Li TL,Chan YL,Chen CL,Wu CJ

更新日期：2009-10-01 00:00:00

abstract：:Increasing knowledge about molecular mechanisms of endogenous RNA interference (RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic acid medicines for treatment of diseases such as cancers. Although RNAi and siRNA have the potential to become powerful therapeutic drugs, their delive...

journal_title：Biomaterials

authors： Kesharwani P,Gajbhiye V,Jain NK

更新日期：2012-10-01 00:00:00

abstract：:Nanoparticle-induced autophagy is crucial for its metabolism, cytotoxicity and therapy potency, but little is known about how the host immune system would respond to it. In this study, we demonstrated that two clinically used superparamagnetic iron oxide nanoparticles (SPIONs) specifically induced macrophage autophagy...

journal_title：Biomaterials

authors： Jin R,Liu L,Zhu W,Li D,Yang L,Duan J,Cai Z,Nie Y,Zhang Y,Gong Q,Song B,Wen L,Anderson JM,Ai H

更新日期：2019-05-01 00:00:00

abstract：:Valvular interstitial cells (VICs) actively maintain and repair heart valve tissue; however, persistent activation of VICs to a myofibroblast phenotype can lead to aortic stenosis. To better understand and quantify how microenvironmental cues influence VIC phenotype and myofibroblast activation, we compared expression...

journal_title：Biomaterials

authors： Mabry KM,Payne SZ,Anseth KS

更新日期：2016-01-01 00:00:00

abstract：:Notorious bacterial biofilms are becoming severe threats to public health worldwide. As the important component in biofilm extracellular polymeric substances (EPS), extracellular DNA (eDNA) has been manifested to connect different EPS components and bacteria together, leading biofilms hard to eliminate. Herein a serie...

journal_title：Biomaterials

authors： Liu Z,Wang F,Ren J,Qu X

更新日期：2019-07-01 00:00:00

abstract：:Amyloid fibrils and plaques are detected in the brain tissue of patients affected by Alzheimer's disease, but have also been found as part of normal physiological processes such as bacterial adhesion. Due to their highly organized structures, amyloid proteins have also been used for the development of nanomaterials, f...

journal_title：Biomaterials

authors： Paparcone R,Buehler MJ

更新日期：2011-05-01 00:00:00

abstract：:A novel low-pressure radio-frequency plasma treatment protocol was developed to achieve the effective through-thickness surface modification of large porous poly (D,L-lactide) (PDLLA) polymer scaffolds using air or water: ammonia plasma treatments. Polymer films were modified as controls. Scanning electron micrographs...

journal_title：Biomaterials

authors： Safinia L,Datan N,Höhse M,Mantalaris A,Bismarck A

更新日期：2005-12-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an autoimmune disease. Antibodies directed mainly against DNA and/or phospholipids are present in the serum of SLE patients. Therefore phosphorylated polystyrene derivatives acting as DNA-like polymers should be able to interact with the SLE anti-DNA antibodies. Such functional po...

journal_title：Biomaterials

authors： Letourneur D,Jozefowicz M

更新日期：1992-01-01 00:00:00