Investigation of the torque-tension characteristics of a flanged external fixator pin.

abstract：:Topographic features can modulate cell behaviours such as proliferation, migration, differentiation and apoptosis. Biochemical mechanotransduction implies the conversion of mechanical forces (e.g. changes in cell spreading and morphology from changing surface topography) into biochemical signal via biomolecules. Still...

journal_title：Biomaterials

authors： Kantawong F,Burgess KE,Jayawardena K,Hart A,Burchmore RJ,Gadegaard N,Oreffo RO,Dalby MJ

更新日期：2009-09-01 00:00:00

abstract：:The ability of different calcium phosphate to activate the complement system is studied by crossed immunoelectrophoresis demonstrating conversion of C3 to C3b. Complement consumption is determined by a haemolytic assay CH50. Hydroxyapatite powders after sintering induce a significant conversion of C3 and reduction of ...

journal_title：Biomaterials

authors： Klein CP,de Groot K,van Kamp G

更新日期：1983-07-01 00:00:00

abstract：:In designing and developing various biomaterials, the influence of substrate properties, like surface topography, stiffness and wettability on the cell functionality has been investigated widely. However, such study to probe into the influence of the substrate conductivity on cell fate processes is rather limited. In ...

journal_title：Biomaterials

authors： Thrivikraman G,Mallik PK,Basu B

更新日期：2013-09-01 00:00:00

abstract：:Crystalline carbonate- and sodium-and-carbonate-substituted hydroxyapatite (CO3HAp and NaCO3HAp) powders were prepared at room temperature via a heterogeneous reaction between Ca(OH)2/CaCO3/Na2CO3 and (NH4)2HPO4 aqueous solution using the mechanochemical hydrothermal route. X-ray diffraction, infrared spectroscopy, th...

journal_title：Biomaterials

authors： Suchanek WL,Shuk P,Byrappa K,Riman RE,TenHuisen KS,Janas VF

更新日期：2002-02-01 00:00:00

abstract：:While subcutaneous tissue has been proposed as a potential site for pancreatic islet transplantation, concern remains that the microvasculature of subcutaneous tissue is too poor to support transplanted islets. In an effort to overcome this limitation, we evaluated whether fibrin gel with human adipose-derived stem ce...

journal_title：Biomaterials

authors： Bhang SH,Jung MJ,Shin JY,La WG,Hwang YH,Kim MJ,Kim BS,Lee DY

更新日期：2013-10-01 00:00:00

abstract：:Starvation therapy to slow down the tumor growth by cutting off its energy supply has been proposed to be an alternative therapeutic strategy for cancer treatment. Herein, glucose oxidase (GOx) is loaded into stealth liposomes and act as the glucose and oxygen elimination agent to trigger the conversion of glucose and...

journal_title：Biomaterials

authors： Zhang R,Feng L,Dong Z,Wang L,Liang C,Chen J,Ma Q,Zhang R,Chen Q,Wang Y,Liu Z

更新日期：2018-04-01 00:00:00

abstract：:Current synthetic vascular grafts possess a significant mechanical mismatch compared to the native vasculature and do not permit endothelialization; both of these deficiencies contribute to the relatively high rate of failure of many synthetic grafts. In this communication, we report the modification of polyurethane (...

journal_title：Biomaterials

authors： Chuang TW,Masters KS

更新日期：2009-10-01 00:00:00

abstract：:Today, corneal wounds are repaired using nylon sutures. Yet there are a number of complications associated with suturing the cornea, and thus there is interest in an adhesive to replace or supplement sutures in the repair of corneal wounds. We are designing and evaluating corneal adhesives prepared from dendrimers--si...

journal_title：Biomaterials

authors： Grinstaff MW

更新日期：2007-12-01 00:00:00

abstract：:Optimal nano-sized drug carrier requires long blood circulation, selective extravasation, and efficient cell uptake. Here we develop a charge-convertible nanoplatform based on Pt(IV) prodrug loaded NaYF4:Yb,Tm upconversion nanoparticles (UCNs), followed by coating a layer of PEG-PAH-DMMA polymer (UCNs-Pt(IV)@PEG-PAH-D...

journal_title：Biomaterials

authors： Xu J,Kuang Y,Lv R,Yang P,Li C,Bi H,Liu B,Yang D,Dai Y,Gai S,He F,Xing B,Lin J

更新日期：2017-06-01 00:00:00

abstract：:Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was loaded with doxorubicin (DOX) through hydrazone, an acid-responsive linker, and was functionalized with angiopep-2, a specific ligand of lo...

journal_title：Biomaterials

authors： Ruan S,Yuan M,Zhang L,Hu G,Chen J,Cun X,Zhang Q,Yang Y,He Q,Gao H

更新日期：2015-01-01 00:00:00

abstract：:In spite of good prospects for bone morphogenetic proteins (BMP) applications, an ideal carrier system for BMPs has not yet been identified. The purpose of this study was to evaluate the osteogenic effect of a fibrin-fibronectin sealing system (FFSS) combined with beta-tricalcium phosphate (beta-TCP) as a carrier syst...

journal_title：Biomaterials

authors： Hong SJ,Kim CS,Han DK,Cho IH,Jung UW,Choi SH,Kim CK,Cho KS

更新日期：2006-07-01 00:00:00

abstract：:A comparative study of in vitro bioactivity of a sol-gel glass with composition 55% SiO2-41%CaO-4%P2O5 has been carried out by soaking it in a simulated body fluid (SBF) with and without exchange of this solution. When SBF is kept constant (static assay) the solution composition changes, increasing the Ca2+ concentrat...

journal_title：Biomaterials

authors： Rámila A,Vallet-Regí M

更新日期：2001-08-01 00:00:00

abstract：:pH-triggered lipid-membranes designed from biophysical principles are evaluated in the form of targeted liposomal doxorubicin with the aim to ultimately better control the growth of vascularized tumors. We compare the antitumor efficacy of anti-HER2/neu pH-triggered lipid vesicles encapsulating doxorubicin to the anti...

journal_title：Biomaterials

authors： Bandekar A,Karve S,Chang MY,Mu Q,Rotolo J,Sofou S

更新日期：2012-06-01 00:00:00

abstract：:A series of novel cationic star polymers were synthesized by conjugating multiple oligoethylenimine (OEI) arms onto an alpha-cyclodextrin (alpha-CD) core as nonviral gene delivery vectors. The molecular structures of the alpha-CD-OEI star polymers, which contained linear or branched OEI arms with different chain lengt...

journal_title：Biomaterials

authors： Yang C,Li H,Goh SH,Li J

更新日期：2007-07-01 00:00:00

abstract：:The aim of this in vitro study was to evaluate the antimicrobial activity, the substantivity, and surface effects of the inclusion compound tetracycline: beta-cyclodextrin on bovine roots. The antimicrobial activity was assessed by dentine slabs which had been immersed in the inclusion complex in concentrations 8.0%, ...

journal_title：Biomaterials

authors： Pataro AL,Franco CF,Santos VR,Cortés ME,Sinisterra RD

更新日期：2003-03-01 00:00:00

abstract：:A series of polymer and copolymer networks with varying hydrophilicity and distribution of the hydrophilic groups was synthesized and biologically tested with monolayer culture of human chondrocytes in vitro. Cell viability (MTT), proliferation (BrdU incorporation) and aggrecan expression (PG ELISA) were quantified at...

journal_title：Biomaterials

authors： Pérez Olmedilla M,Garcia-Giralt N,Pradas MM,Ruiz PB,Gómez Ribelles JL,Palou EC,García JC

更新日期：2006-03-01 00:00:00

abstract：:This paper describes a method of foaming a polymer system comprising poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEMA/THFMA), characterisation of the resulting porosity and use of the foam for chondrocyte culture. The potential for this polymer system to support cartilage repair has been investigated pre...

journal_title：Biomaterials

authors： Barry JJ,Gidda HS,Scotchford CA,Howdle SM

更新日期：2004-08-01 00:00:00

abstract：:The changes in protein adsorption onto aluminium surfaces coated with different thicknesses of oxide layers were examined. The oxide layers on aluminium substrates were derived by the anodizing technique. Protein adsorption studies were conducted using 125I-labelled albumin and the amount of albumin adsorbed was estim...

journal_title：Biomaterials

authors： Sharma CP,Sunny MC

更新日期：1990-05-01 00:00:00

abstract：:Dual-functional liposomes with pH-responsive cell-penetrating peptide (CPP) and active targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of synthetic tumor pH-triggered CPPs rich in arginines and histidines were screened by comparing tumor cellular uptake efficiency at pH 6.4 wi...

journal_title：Biomaterials

authors： Jiang T,Zhang Z,Zhang Y,Lv H,Zhou J,Li C,Hou L,Zhang Q

更新日期：2012-12-01 00:00:00

abstract：:Bone tissue engineering strategies are fundamentally based upon porous scaffold materials that serve as a support for ingrowth of host cells and/or provide a substrate for exogenously delivered cells. Here we report the application of a surface calcium phosphate (CaP) mineral layer to a macroporous polymeric/CaP compo...

journal_title：Biomaterials

authors： Lickorish D,Guan L,Davies JE

更新日期：2007-03-01 00:00:00

abstract：:Construction of bio-mimetic well-organized three-dimensional (3D) tissue with various cells in vitro is one of the ultimate goals of tissue engineering. In particular, fabrication of vasculature in 3D tissue is one of the most important tasks in tissue engineering, because a vascular network is indispensable for almos...

journal_title：Biomaterials

authors： Muraoka M,Shimizu T,Itoga K,Takahashi H,Okano T

更新日期：2013-01-01 00:00:00

abstract：:To achieve an optimum drug delivery such as targeting or controlled release utilizing bioconjugation with polymeric modifier, the conjugate between drugs and polymeric modifiers must be designed to show desirable pharmacokinetic characteristics in vivo. In this study, we assessed the biopharmaceutical properties of va...

journal_title：Biomaterials

authors： Kaneda Y,Tsutsumi Y,Yoshioka Y,Kamada H,Yamamoto Y,Kodaira H,Tsunoda S,Okamoto T,Mukai Y,Shibata H,Nakagawa S,Mayumi T

更新日期：2004-07-01 00:00:00

abstract：:Skeletal muscle is a highly organized tissue in which the extracellular matrix (ECM) is composed of highly-aligned cables of collagen with nanoscale feature sizes, and provides structural and functional support to muscle fibers. As such, the transplantation of disorganized tissues or the direct injection of cells into...

journal_title：Biomaterials

authors： Yang HS,Ieronimakis N,Tsui JH,Kim HN,Suh KY,Reyes M,Kim DH

更新日期：2014-02-01 00:00:00

abstract：:Melanoma inhibitory activity (MIA), also referred to as cartilage derived retinoic acid-sensitive protein (CD-RAP), is detected physiologically in cartilage tissue and pathologically in malignant melanomas. To measure MIA/CD-RAP quantitatively we developed a sensitive ELISA system. Recently, we described diagnostic ap...

journal_title：Biomaterials

authors： Bosserhoff AK,Buettner R

更新日期：2003-08-01 00:00:00

abstract：:Nickel-titanium (NiTi, nitinol) shape memory alloy was nitrided using an original powder immersion reaction assisted coating (PIRAC) method in order to modify its surface properties. PIRAC nitriding method is based on annealing the samples in the atmosphere of highly reactive nitrogen supplied by decomposition of unst...

journal_title：Biomaterials

authors： Starosvetsky D,Gotman I

更新日期：2001-07-01 00:00:00

abstract：:Material features proved to exert a potent influence on cell behaviour in terms of adhesion, migration and differentiation. In particular, biophysical and biochemical signals on material surfaces are able to affect focal adhesion distribution and cytoskeletal assemblies, which are known to regulate signalling pathways...

journal_title：Biomaterials

authors： Natale CF,Ventre M,Netti PA

更新日期：2014-03-01 00:00:00

abstract：:The aim of this study was to investigate the effects of alginate and agarose on the response of bone marrow stromal cells (BMSCs) to chondrogenic stimuli. Rat BMSCs were expanded in monolayer culture with or without FGF-2 supplementation. Cells were then seeded in 2% alginate and agarose gels and cultured in media wit...

journal_title：Biomaterials

authors： Coleman RM,Case ND,Guldberg RE

更新日期：2007-04-01 00:00:00

abstract：:The coupling of specific antibodies to imaging agents often improves imaging specificity. However, free amine groups designed for the coupling can cause nonspecific binding of the imaging agents. We report here development of a nanocarrier, MnMEIO-silane-NH2-mPEG nanoparticles (NPs), consisting of a manganese-doped ir...

journal_title：Biomaterials

authors： Wu SC,Lin KL,Wang TP,Tzou SC,Singh G,Chen MH,Cheng TL,Chen CY,Liu GC,Lee TW,Hu SH,Wang YM

更新日期：2013-05-01 00:00:00

abstract：:Excessive production of reactive oxygen species (ROS) is a hallmark feature in nanomaterials (NMs) induced cellular toxicity. However, the inter-relationship between NMs induced ROS generation and the cells innate ability to regulate intracellular ROS level in effecting a particular cellular outcome is currently under...

journal_title：Biomaterials

authors： Setyawati MI,Tay CY,Leong DT

更新日期：2013-12-01 00:00:00

abstract：:In this work, we studied the shell structure of the Nautilus pompilius Linnaeus by using analytical techniques of scanning (SEM) and transmission electron microscopy (TEM) and X-ray diffraction. The main objective of this study is the structural characterization of Nautilus shell at different length levels, from micro...

journal_title：Biomaterials

authors： Velázquez-Castillo RR,Reyes-Gasga J,García-Gutierrez DI,Jose-Yacaman M

更新日期：2006-09-01 00:00:00