Investigation of the torque-tension characteristics of a flanged external fixator pin.

abstract：:Silica nanoparticles (SiO2-NPs) has been extensively exploited in biomedical fields and mostly designed to enter the circulatory system, however, few studies focused on the potential adverse effects of SiO2-NPs exposure on the blood-brain barrier (BBB) that serves as a critical barrier between the central nervous syst...

journal_title：Biomaterials

authors： Liu X,Sui B,Sun J

更新日期：2017-03-01 00:00:00

abstract：:There are few suitable techniques available to sterilize biodegradable polyester three-dimensional tissue engineering scaffolds because they are susceptible to degradation and/or morphological degeneration by high temperature and pressure. We used a novel polyllactide-co-glycolide) scaffold (Osteofoam) to determine th...

journal_title：Biomaterials

authors： Holy CE,Cheng C,Davies JE,Shoichet MS

更新日期：2001-01-01 00:00:00

abstract：:Injectable, biodegradable scaffolds are important biomaterials for tissue engineering and drug delivery. Hydrogels derived from natural polysaccharides are ideal scaffolds as they resemble the extracellular matrices of tissues comprised of various glycosaminoglycans (GAGs). Here, we report a new class of biocompatible...

journal_title：Biomaterials

authors： Tan H,Chu CR,Payne KA,Marra KG

更新日期：2009-05-01 00:00:00

abstract：:Aberrant regulation of angiogenesis supply sufficient oxygen and nutrients to exacerbate tumor progression and metastasis. Taking this hallmark of cancer into account, reported here is a self-monitoring and triple-collaborative therapy system by auto-fluorescent polymer nanotheranostics which could be concurrently aga...

journal_title：Biomaterials

authors： Shao L,Li Q,Zhao C,Lu J,Li X,Chen L,Deng X,Ge G,Wu Y

更新日期：2019-02-01 00:00:00

abstract：:Novel biological adhesives made from chitin derivatives were prepared and evaluated for their adhesive properties and biocompatibility. Chitin derivatives with acrylic groups, such as 2-hydroxy-3-methacryloyloxypropylated carboxymethyl chitin (HMA-CM-chitin), were synthesized and cured by the addition of an aqueous hy...

journal_title：Biomaterials

authors： Azuma K,Nishihara M,Shimizu H,Itoh Y,Takashima O,Osaki T,Itoh N,Imagawa T,Murahata Y,Tsuka T,Izawa H,Ifuku S,Minami S,Saimoto H,Okamoto Y,Morimoto M

更新日期：2015-02-01 00:00:00

abstract：:Acetaminophen (APAP) is the most widely used analgesic and its overdose, intentional or unintentional, is known to cause massive oxidative stress and liver tissue damages characterized by hepatocellular apoptosis and hemorrhagic necrosis, leading to acute liver failure (ALF). There has been great interest in the use o...

journal_title：Biomaterials

authors： Ko E,Jeong D,Kim J,Park S,Khang G,Lee D

更新日期：2014-04-01 00:00:00

abstract：:This paper presents for the first time a mathematical model for a mechanism of controlled drug release involving both ion exchange and transient counter diffusion of a drug and counterions. Numerical analysis was conducted to study the effect of different factors on drug release kinetics including environmental condit...

journal_title：Biomaterials

authors： Abdekhodaie MJ,Wu XY

更新日期：2008-04-01 00:00:00

abstract：:In this study, the behavior of neural stem cells from embryonic rat cerebral cortex were compared on the chitosan and poly(vinylidene fluoride) (PVDF) substrates at single-cell and neurosphere level. It was found that chitosan and PVDF substrates inhibited the proliferation and differentiation of single neural stem ce...

journal_title：Biomaterials

authors： Hung CH,Lin YL,Young TH

更新日期：2006-09-01 00:00:00

abstract：:Dental amalgam prepared from high copper and conventional alloys was evaluated for its compressive strength as a function of deformation rate. Results showed that the compressive strength rose to a maximum as deformation rate increased and then began to fall at higher deformation rates. Crack propagation predominated ...

journal_title：Biomaterials

authors： Zardiackas LD,Anderson L Jr

更新日期：1986-07-01 00:00:00

abstract：:Irradiated, thermally stabilized, highly cross-linked UHMWPE bearings have demonstrated superior wear performance and improved in vitro oxidation resistance compared with terminally gamma-sterilized bearings, yet retrieval analysis reveals unanticipated in vivo oxidation in these materials despite fewer or no measurab...

journal_title：Biomaterials

authors： Reinitz SD,Currier BH,Levine RA,Van Citters DW

更新日期：2014-05-01 00:00:00

abstract：:Fibrosis affects most organs, it results in replacement of normal parenchymal tissue with collagen-rich extracellular matrix, which compromises tissue architecture and ultimately causes loss of function of the affected organ. Biochemical pathways that contribute to fibrosis have been extensively studied, but the role ...

journal_title：Biomaterials

authors： Varkey M,Ding J,Tredget EE,Wound Healing Research Group.

更新日期：2014-12-01 00:00:00

abstract：:There are many ways to influence cell activities, and biomaterials with functional groups attached is an attractive method that clearly has the ability to modulate cell behavior. The evidence is clear that biomaterials, with or without growth factors and cells, have resulted in numerous products for the regenerative m...

journal_title：Biomaterials

authors： Ratcliffe A

更新日期：2011-06-01 00:00:00

abstract：:Silicone elastomers have been used as implants in orthopaedics for replacements of small joints such as the metacarpophalangeal joint. A series of experiments was conducted an axially tensioned silicone elastomer tendon spacer samples to determine whether there is a relationship between stress in the material and imag...

journal_title：Biomaterials

authors： Abel EW,Wheeler KI,Chudek JA,Hunter G,Som FM

更新日期：1998-01-01 00:00:00

abstract：:Microcontact printing techniques were used to modify silicon substrates with arrays of hexagonal features of N1[3-(trimethoxysilyl) propyl]diethylenetriamine (DETA) surrounded by octadecyltrichlorosilane (OTS), which are hydrophilic, cell-adhesive and hydrophobic, non-adhesive organosilanes, respectively. In the prese...

journal_title：Biomaterials

authors： Kam L,Shain W,Turner JN,Bizios R

更新日期：1999-12-01 00:00:00

abstract：:Chemotherapeutic agents often cause severe side effects because they produce a similar cytotoxicity in both cancerous and healthy cells. In this study, a rational strategy was implemented to take advantage of a combination of both tumor microenvironment-sensitive polypeptides (TMSP) and folate to create a more selecti...

journal_title：Biomaterials

authors： Gao W,Xiang B,Meng TT,Liu F,Qi XR

更新日期：2013-05-01 00:00:00

abstract：:Current synthetic vascular grafts possess a significant mechanical mismatch compared to the native vasculature and do not permit endothelialization; both of these deficiencies contribute to the relatively high rate of failure of many synthetic grafts. In this communication, we report the modification of polyurethane (...

journal_title：Biomaterials

authors： Chuang TW,Masters KS

更新日期：2009-10-01 00:00:00

abstract：:A novel biodegradable polymer blend was developed for potential biomedical applications. A 50:50 poly(lactide-co-glycolide) (PLAGA) was blended in a 50:50 ratio with the followiing polyphosphazenes (PPHOS): poly[(25% ethyl glycinato)(75% p-methylphenoxy)phosphazene[, poly[(50% ethyl glycinato)(50% p-methylphenoxy)phos...

journal_title：Biomaterials

authors： Ibim SE,Ambrosio AM,Kwon MS,El-Amin SF,Allcock HR,Laurencin CT

更新日期：1997-12-01 00:00:00

abstract：:The maximum capacity of a hydrophobic adsorbent is interpreted in terms of square or hexagonal (cubic and face-centered-cubic, FCC) interfacial packing models of adsorbed blood proteins in a way that accommodates experimental measurements by the solution-depletion method and quartz-crystal-microbalance (QCM) for the h...

journal_title：Biomaterials

authors： Kao P,Parhi P,Krishnan A,Noh H,Haider W,Tadigadapa S,Allara DL,Vogler EA

更新日期：2011-02-01 00:00:00

abstract：:Decellularized adipose tissue (DAT) has shown promise as an adipogenic bioscaffold for soft tissue augmentation and reconstruction. The objective of the current study was to investigate the effects of allogeneic adipose-derived stem/stromal cells (ASCs) on in vivo fat regeneration in DAT bioscaffolds using an immunoco...

journal_title：Biomaterials

authors： Han TT,Toutounji S,Amsden BG,Flynn LE

更新日期：2015-12-01 00:00:00

abstract：:The micro-environment is an important factor in the differentiation of cultured stem cells for the purpose of site specific transplantation. In an attempt to optimize differentiation conditions, co-culture systems composed of both stem cells and primary cells or cell lines were used in hydrogel with in vitro and in vi...

journal_title：Biomaterials

authors： Park JS,Yang HN,Woo DG,Kim H,Na K,Park KH

更新日期：2010-10-01 00:00:00

abstract：:The metastatic spread of cancer cells from the primary tumor to distant sites leads to a poor prognosis in cancers originating from multiple organs. Increasing evidence has linked selectin-based adhesion between circulating tumor cells (CTCs) and endothelial cells of the microvasculature to metastatic dissemination, i...

journal_title：Biomaterials

authors： Mitchell MJ,Castellanos CA,King MR

更新日期：2015-07-01 00:00:00

abstract：:Compared to soluble cytokines, surface-tethered ligands can deliver biological signalling with precise control of spatial positioning and concentration. A strategy that immobilises ligand molecules on a surface in a uniform orientation using non-cleavable linkages under physiological conditions would enhance the speci...

journal_title：Biomaterials

authors： Lee EJ,Be CL,Vinson AR,Riches AG,Fehr F,Gardiner J,Gengenbach TR,Winkler DA,Haylock D

更新日期：2015-01-01 00:00:00

abstract：:In this study, a type of intracellular redox-triggered hollow mesoporous silica nanoreservoirs (HMSNs) with tumor specificity was developed in order to deliver anticancer drug (i.e., doxorubicin (DOX)) to the target tumor cells with high therapeutic efficiency and reduced side effects. Firstly, adamantanamine was graf...

journal_title：Biomaterials

authors： Luo Z,Hu Y,Cai K,Ding X,Zhang Q,Li M,Ma X,Zhang B,Zeng Y,Li P,Li J,Liu J,Zhao Y

更新日期：2014-09-01 00:00:00

abstract：:Implanted materials, such as medical devices, provoke the body to initiate an inflammatory reaction, known as the foreign body reaction (FBR), which causes several complications for example in hip prostheses, silicone implants, peritoneal dialysis catheters and left ventricular assist devices. FBR is initiated by macr...

journal_title：Biomaterials

authors： Vranken I,De Visscher G,Lebacq A,Verbeken E,Flameng W

更新日期：2008-03-01 00:00:00

abstract：:The recreation of an in vitro microenvironment to understand and manipulate the proliferation and migration of invasive breast cancer cells may allow one to put a halt to their metastasis capacity. Invasive cancer cells have been linked to embryonic stem (ES) cells as they possess certain similar characteristics and g...

journal_title：Biomaterials

authors： Raof NA,Raja WK,Castracane J,Xie Y

更新日期：2011-06-01 00:00:00

abstract：:Effective antimicrobial agents are important arsenals in our perennial fight against communicable diseases, hospital-acquired and surgical site multidrug-resistant infections. In this study, we devise a strategy for the development of highly efficacious and skin compatible yet inexpensive water-soluble macromolecular ...

journal_title：Biomaterials

authors： Liu S,Ono RJ,Wu H,Teo JY,Liang ZC,Xu K,Zhang M,Zhong G,Tan JP,Ng M,Yang C,Chan J,Ji Z,Bao C,Kumar K,Gao S,Lee A,Fevre M,Dong H,Ying JY,Li L,Fan W,Hedrick JL,Yang YY

更新日期：2017-05-01 00:00:00

abstract：:AuCu and AuAg alloys (30 at. % Au) have been immersed in aqueous solutions of chloride and sulphide with additions of protein (mucin). The surfaces of the alloys were subsequently analysed by means of ESCA and compared with previous and similar tests without addition of mucin. No noticeable effect of the mucin additio...

journal_title：Biomaterials

authors： Herø H,Hultquist G,Odén A

更新日期：1985-11-01 00:00:00

abstract：:The emergence of combinatorial chemistries and the increased discovery of natural compounds have led to the production of expansive libraries of drug candidates and vast numbers of compounds with potentially interesting biological activities. Despite broad interest in high throughput screening (HTS) across varied fiel...

journal_title：Biomaterials

authors： Wu J,Wheeldon I,Guo Y,Lu T,Du Y,Wang B,He J,Hu Y,Khademhosseini A

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study was to develop an effective drug delivery system for the simultaneous topical delivery of two anti-inflammatory drugs, spantide II (SP) and ketoprofen (KP). To achieve this primary goal, we have developed a skin permeating nanogel system (SPN) containing surface modified polymeric bilayered nanop...

journal_title：Biomaterials

authors： Shah PP,Desai PR,Patel AR,Singh MS

更新日期：2012-02-01 00:00:00

abstract：:A practical method of photocrosslinking high molecular weight poly(trimethylene carbonate)(PTMC) is presented. Flexible, elastomeric and biodegradable networks could be readily prepared by UV irradiating PTMC films containing pentaerythritol triacrylate (PETA) and a photoinitiator. The network characteristics, mechani...

journal_title：Biomaterials

authors： Bat E,Kothman BH,Higuera GA,van Blitterswijk CA,Feijen J,Grijpma DW

更新日期：2010-11-01 00:00:00