Investigation of the torque-tension characteristics of a flanged external fixator pin.


:The torque-tension characteristics of standard, conical and flanged external fixator pins and a cortical screw were compared using a commercially available testing apparatus. The flanged pin and the screw were similar in behaviour, and converted torque into tension more efficiently than conical and standard external fixator pins.






Oni OO,Batchelor JS




Has Abstract


1995-11-01 00:00:00














  • Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling.

    abstract::Topographic features can modulate cell behaviours such as proliferation, migration, differentiation and apoptosis. Biochemical mechanotransduction implies the conversion of mechanical forces (e.g. changes in cell spreading and morphology from changing surface topography) into biochemical signal via biomolecules. Still...


    pub_type: 杂志文章


    authors: Kantawong F,Burgess KE,Jayawardena K,Hart A,Burchmore RJ,Gadegaard N,Oreffo RO,Dalby MJ

    更新日期:2009-09-01 00:00:00

  • Activation of complement C3 by different calcium phosphate powders.

    abstract::The ability of different calcium phosphate to activate the complement system is studied by crossed immunoelectrophoresis demonstrating conversion of C3 to C3b. Complement consumption is determined by a haemolytic assay CH50. Hydroxyapatite powders after sintering induce a significant conversion of C3 and reduction of ...


    pub_type: 杂志文章


    authors: Klein CP,de Groot K,van Kamp G

    更新日期:1983-07-01 00:00:00

  • Substrate conductivity dependent modulation of cell proliferation and differentiation in vitro.

    abstract::In designing and developing various biomaterials, the influence of substrate properties, like surface topography, stiffness and wettability on the cell functionality has been investigated widely. However, such study to probe into the influence of the substrate conductivity on cell fate processes is rather limited. In ...


    pub_type: 杂志文章


    authors: Thrivikraman G,Mallik PK,Basu B

    更新日期:2013-09-01 00:00:00

  • Mechanochemical-hydrothermal synthesis of carbonated apatite powders at room temperature.

    abstract::Crystalline carbonate- and sodium-and-carbonate-substituted hydroxyapatite (CO3HAp and NaCO3HAp) powders were prepared at room temperature via a heterogeneous reaction between Ca(OH)2/CaCO3/Na2CO3 and (NH4)2HPO4 aqueous solution using the mechanochemical hydrothermal route. X-ray diffraction, infrared spectroscopy, th...


    pub_type: 杂志文章


    authors: Suchanek WL,Shuk P,Byrappa K,Riman RE,TenHuisen KS,Janas VF

    更新日期:2002-02-01 00:00:00

  • Mutual effect of subcutaneously transplanted human adipose-derived stem cells and pancreatic islets within fibrin gel.

    abstract::While subcutaneous tissue has been proposed as a potential site for pancreatic islet transplantation, concern remains that the microvasculature of subcutaneous tissue is too poor to support transplanted islets. In an effort to overcome this limitation, we evaluated whether fibrin gel with human adipose-derived stem ce...


    pub_type: 杂志文章


    authors: Bhang SH,Jung MJ,Shin JY,La WG,Hwang YH,Kim MJ,Kim BS,Lee DY

    更新日期:2013-10-01 00:00:00

  • Glucose & oxygen exhausting liposomes for combined cancer starvation and hypoxia-activated therapy.

    abstract::Starvation therapy to slow down the tumor growth by cutting off its energy supply has been proposed to be an alternative therapeutic strategy for cancer treatment. Herein, glucose oxidase (GOx) is loaded into stealth liposomes and act as the glucose and oxygen elimination agent to trigger the conversion of glucose and...


    pub_type: 杂志文章


    authors: Zhang R,Feng L,Dong Z,Wang L,Liang C,Chen J,Ma Q,Zhang R,Chen Q,Wang Y,Liu Z

    更新日期:2018-04-01 00:00:00

  • Regulation of polyurethane hemocompatibility and endothelialization by tethered hyaluronic acid oligosaccharides.

    abstract::Current synthetic vascular grafts possess a significant mechanical mismatch compared to the native vasculature and do not permit endothelialization; both of these deficiencies contribute to the relatively high rate of failure of many synthetic grafts. In this communication, we report the modification of polyurethane (...


    pub_type: 杂志文章


    authors: Chuang TW,Masters KS

    更新日期:2009-10-01 00:00:00

  • Designing hydrogel adhesives for corneal wound repair.

    abstract::Today, corneal wounds are repaired using nylon sutures. Yet there are a number of complications associated with suturing the cornea, and thus there is interest in an adhesive to replace or supplement sutures in the repair of corneal wounds. We are designing and evaluating corneal adhesives prepared from dendrimers--si...


    pub_type: 杂志文章,评审


    authors: Grinstaff MW

    更新日期:2007-12-01 00:00:00

  • Charge convertibility and near infrared photon co-enhanced cisplatin chemotherapy based on upconversion nanoplatform.

    abstract::Optimal nano-sized drug carrier requires long blood circulation, selective extravasation, and efficient cell uptake. Here we develop a charge-convertible nanoplatform based on Pt(IV) prodrug loaded NaYF4:Yb,Tm upconversion nanoparticles (UCNs), followed by coating a layer of PEG-PAH-DMMA polymer (UCNs-Pt(IV)@PEG-PAH-D...


    pub_type: 杂志文章


    authors: Xu J,Kuang Y,Lv R,Yang P,Li C,Bi H,Liu B,Yang D,Dai Y,Gai S,He F,Xing B,Lin J

    更新日期:2017-06-01 00:00:00

  • Tumor microenvironment sensitive doxorubicin delivery and release to glioma using angiopep-2 decorated gold nanoparticles.

    abstract::Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was loaded with doxorubicin (DOX) through hydrazone, an acid-responsive linker, and was functionalized with angiopep-2, a specific ligand of lo...


    pub_type: 杂志文章


    authors: Ruan S,Yuan M,Zhang L,Hu G,Chen J,Cun X,Zhang Q,Yang Y,He Q,Gao H

    更新日期:2015-01-01 00:00:00

  • The effect of a fibrin-fibronectin/beta-tricalcium phosphate/recombinant human bone morphogenetic protein-2 system on bone formation in rat calvarial defects.

    abstract::In spite of good prospects for bone morphogenetic proteins (BMP) applications, an ideal carrier system for BMPs has not yet been identified. The purpose of this study was to evaluate the osteogenic effect of a fibrin-fibronectin sealing system (FFSS) combined with beta-tricalcium phosphate (beta-TCP) as a carrier syst...


    pub_type: 杂志文章


    authors: Hong SJ,Kim CS,Han DK,Cho IH,Jung UW,Choi SH,Kim CK,Cho KS

    更新日期:2006-07-01 00:00:00

  • Static and dynamic in vitro study of a sol-gel glass bioactivity.

    abstract::A comparative study of in vitro bioactivity of a sol-gel glass with composition 55% SiO2-41%CaO-4%P2O5 has been carried out by soaking it in a simulated body fluid (SBF) with and without exchange of this solution. When SBF is kept constant (static assay) the solution composition changes, increasing the Ca2+ concentrat...


    pub_type: 杂志文章


    authors: Rámila A,Vallet-Regí M

    更新日期:2001-08-01 00:00:00

  • Antitumor efficacy following the intracellular and interstitial release of liposomal doxorubicin.

    abstract::pH-triggered lipid-membranes designed from biophysical principles are evaluated in the form of targeted liposomal doxorubicin with the aim to ultimately better control the growth of vascularized tumors. We compare the antitumor efficacy of anti-HER2/neu pH-triggered lipid vesicles encapsulating doxorubicin to the anti...


    pub_type: 杂志文章


    authors: Bandekar A,Karve S,Chang MY,Mu Q,Rotolo J,Sofou S

    更新日期:2012-06-01 00:00:00

  • Cationic star polymers consisting of alpha-cyclodextrin core and oligoethylenimine arms as nonviral gene delivery vectors.

    abstract::A series of novel cationic star polymers were synthesized by conjugating multiple oligoethylenimine (OEI) arms onto an alpha-cyclodextrin (alpha-CD) core as nonviral gene delivery vectors. The molecular structures of the alpha-CD-OEI star polymers, which contained linear or branched OEI arms with different chain lengt...


    pub_type: 杂志文章


    authors: Yang C,Li H,Goh SH,Li J

    更新日期:2007-07-01 00:00:00

  • Surface effects and desorption of tetracycline supramolecular complex on bovine dentine.

    abstract::The aim of this in vitro study was to evaluate the antimicrobial activity, the substantivity, and surface effects of the inclusion compound tetracycline: beta-cyclodextrin on bovine roots. The antimicrobial activity was assessed by dentine slabs which had been immersed in the inclusion complex in concentrations 8.0%, ...


    pub_type: 杂志文章


    authors: Pataro AL,Franco CF,Santos VR,Cortés ME,Sinisterra RD

    更新日期:2003-03-01 00:00:00

  • Response of human chondrocytes to a non-uniform distribution of hydrophilic domains on poly (ethyl acrylate-co-hydroxyethyl methacrylate) copolymers.

    abstract::A series of polymer and copolymer networks with varying hydrophilicity and distribution of the hydrophilic groups was synthesized and biologically tested with monolayer culture of human chondrocytes in vitro. Cell viability (MTT), proliferation (BrdU incorporation) and aggrecan expression (PG ELISA) were quantified at...


    pub_type: 杂志文章


    authors: Pérez Olmedilla M,Garcia-Giralt N,Pradas MM,Ruiz PB,Gómez Ribelles JL,Palou EC,García JC

    更新日期:2006-03-01 00:00:00

  • Porous methacrylate scaffolds: supercritical fluid fabrication and in vitro chondrocyte responses.

    abstract::This paper describes a method of foaming a polymer system comprising poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEMA/THFMA), characterisation of the resulting porosity and use of the foam for chondrocyte culture. The potential for this polymer system to support cartilage repair has been investigated pre...


    pub_type: 杂志文章


    authors: Barry JJ,Gidda HS,Scotchford CA,Howdle SM

    更新日期:2004-08-01 00:00:00

  • Albumin adsorption on to aluminium oxide and polyurethane surfaces.

    abstract::The changes in protein adsorption onto aluminium surfaces coated with different thicknesses of oxide layers were examined. The oxide layers on aluminium substrates were derived by the anodizing technique. Protein adsorption studies were conducted using 125I-labelled albumin and the amount of albumin adsorbed was estim...


    pub_type: 杂志文章


    authors: Sharma CP,Sunny MC

    更新日期:1990-05-01 00:00:00

  • Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery.

    abstract::Dual-functional liposomes with pH-responsive cell-penetrating peptide (CPP) and active targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of synthetic tumor pH-triggered CPPs rich in arginines and histidines were screened by comparing tumor cellular uptake efficiency at pH 6.4 wi...


    pub_type: 杂志文章


    authors: Jiang T,Zhang Z,Zhang Y,Lv H,Zhou J,Li C,Hou L,Zhang Q

    更新日期:2012-12-01 00:00:00

  • A three-phase, fully resorbable, polyester/calcium phosphate scaffold for bone tissue engineering: Evolution of scaffold design.

    abstract::Bone tissue engineering strategies are fundamentally based upon porous scaffold materials that serve as a support for ingrowth of host cells and/or provide a substrate for exogenously delivered cells. Here we report the application of a surface calcium phosphate (CaP) mineral layer to a macroporous polymeric/CaP compo...


    pub_type: 杂志文章


    authors: Lickorish D,Guan L,Davies JE

    更新日期:2007-03-01 00:00:00

  • Control of the formation of vascular networks in 3D tissue engineered constructs.

    abstract::Construction of bio-mimetic well-organized three-dimensional (3D) tissue with various cells in vitro is one of the ultimate goals of tissue engineering. In particular, fabrication of vasculature in 3D tissue is one of the most important tasks in tissue engineering, because a vascular network is indispensable for almos...


    pub_type: 杂志文章


    authors: Muraoka M,Shimizu T,Itoga K,Takahashi H,Okano T

    更新日期:2013-01-01 00:00:00

  • The use of PVP as a polymeric carrier to improve the plasma half-life of drugs.

    abstract::To achieve an optimum drug delivery such as targeting or controlled release utilizing bioconjugation with polymeric modifier, the conjugate between drugs and polymeric modifiers must be designed to show desirable pharmacokinetic characteristics in vivo. In this study, we assessed the biopharmaceutical properties of va...


    pub_type: 杂志文章


    authors: Kaneda Y,Tsutsumi Y,Yoshioka Y,Kamada H,Yamamoto Y,Kodaira H,Tsunoda S,Okamoto T,Mukai Y,Shibata H,Nakagawa S,Mayumi T

    更新日期:2004-07-01 00:00:00

  • Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy.

    abstract::Skeletal muscle is a highly organized tissue in which the extracellular matrix (ECM) is composed of highly-aligned cables of collagen with nanoscale feature sizes, and provides structural and functional support to muscle fibers. As such, the transplantation of disorganized tissues or the direct injection of cells into...


    pub_type: 杂志文章


    authors: Yang HS,Ieronimakis N,Tsui JH,Kim HN,Suh KY,Reyes M,Kim DH

    更新日期:2014-02-01 00:00:00

  • Establishing the protein MIA (melanoma inhibitory activity) as a marker for chondrocyte differentiation.

    abstract::Melanoma inhibitory activity (MIA), also referred to as cartilage derived retinoic acid-sensitive protein (CD-RAP), is detected physiologically in cartilage tissue and pathologically in malignant melanomas. To measure MIA/CD-RAP quantitatively we developed a sensitive ELISA system. Recently, we described diagnostic ap...


    pub_type: 杂志文章


    authors: Bosserhoff AK,Buettner R

    更新日期:2003-08-01 00:00:00

  • Corrosion behavior of titanium nitride coated Ni-Ti shape memory surgical alloy.

    abstract::Nickel-titanium (NiTi, nitinol) shape memory alloy was nitrided using an original powder immersion reaction assisted coating (PIRAC) method in order to modify its surface properties. PIRAC nitriding method is based on annealing the samples in the atmosphere of highly reactive nitrogen supplied by decomposition of unst...


    pub_type: 杂志文章


    authors: Starosvetsky D,Gotman I

    更新日期:2001-07-01 00:00:00

  • Tuning the material-cytoskeleton crosstalk via nanoconfinement of focal adhesions.

    abstract::Material features proved to exert a potent influence on cell behaviour in terms of adhesion, migration and differentiation. In particular, biophysical and biochemical signals on material surfaces are able to affect focal adhesion distribution and cytoskeletal assemblies, which are known to regulate signalling pathways...


    pub_type: 杂志文章


    authors: Natale CF,Ventre M,Netti PA

    更新日期:2014-03-01 00:00:00

  • Hydrogel effects on bone marrow stromal cell response to chondrogenic growth factors.

    abstract::The aim of this study was to investigate the effects of alginate and agarose on the response of bone marrow stromal cells (BMSCs) to chondrogenic stimuli. Rat BMSCs were expanded in monolayer culture with or without FGF-2 supplementation. Cells were then seeded in 2% alginate and agarose gels and cultured in media wit...


    pub_type: 杂志文章


    authors: Coleman RM,Case ND,Guldberg RE

    更新日期:2007-04-01 00:00:00

  • Imaging specificity of MR-optical imaging agents following the masking of surface charge by poly(ethylene glycol).

    abstract::The coupling of specific antibodies to imaging agents often improves imaging specificity. However, free amine groups designed for the coupling can cause nonspecific binding of the imaging agents. We report here development of a nanocarrier, MnMEIO-silane-NH2-mPEG nanoparticles (NPs), consisting of a manganese-doped ir...


    pub_type: 杂志文章


    authors: Wu SC,Lin KL,Wang TP,Tzou SC,Singh G,Chen MH,Cheng TL,Chen CY,Liu GC,Lee TW,Hu SH,Wang YM

    更新日期:2013-05-01 00:00:00

  • Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway.

    abstract::Excessive production of reactive oxygen species (ROS) is a hallmark feature in nanomaterials (NMs) induced cellular toxicity. However, the inter-relationship between NMs induced ROS generation and the cells innate ability to regulate intracellular ROS level in effecting a particular cellular outcome is currently under...


    pub_type: 杂志文章


    authors: Setyawati MI,Tay CY,Leong DT

    更新日期:2013-12-01 00:00:00

  • Crystal structure characterization of nautilus shell at different length scales.

    abstract::In this work, we studied the shell structure of the Nautilus pompilius Linnaeus by using analytical techniques of scanning (SEM) and transmission electron microscopy (TEM) and X-ray diffraction. The main objective of this study is the structural characterization of Nautilus shell at different length levels, from micro...


    pub_type: 杂志文章


    authors: Velázquez-Castillo RR,Reyes-Gasga J,García-Gutierrez DI,Jose-Yacaman M

    更新日期:2006-09-01 00:00:00