Influence of steroid hormones on protein-platelet interaction at the blood-polymer interface.

abstract：:Methyl methacrylate (MMA) is a volatile liquid widely used in the manufacture of acrylic polymers. In modern dentistry, MMA is the mainstream material in denture bases. MMA has been implicated as primary irritant and sensitizer, which can cause allergic eczematous reaction on the oral mucosa as well as skin. To date, ...

journal_title：Biomaterials

authors： Yang HW,Chou LS,Chou MY,Chang YC

更新日期：2003-08-01 00:00:00

abstract：:A growing number of protein-based fibrous biomaterials have been produced with a cross-β amyloid core yet the long-term effect of these materials on cell viability and the influence of core and non-core protein sequences on viability is not well understood. Here, synthetic bioactive TTR1-RGD and control TTR1-RAD or TT...

journal_title：Biomaterials

authors： Bongiovanni MN,Gras SL

更新日期：2015-04-01 00:00:00

abstract：:Direct reprogramming strategies enable rapid conversion of somatic cells to cardiomyocytes or cardiomyocyte-like cells without going through the pluripotent state. A recently described protocol couples Yamanaka factor induction with pluripotency inhibition followed by BMP4 treatment to achieve rapid reprogramming of m...

journal_title：Biomaterials

authors： Smith AW,Hoyne JD,Nguyen PK,McCreedy DA,Aly H,Efimov IR,Rentschler S,Elbert DL

更新日期：2013-09-01 00:00:00

abstract：:Following an original synthesis route, we have prepared a single-component calcium phosphate apatite-like powder which settles and hardens when mixed with deionized water in an approximative 1.2 g:1 ml ratio. This paper describes the first physico-chemical studies and characterizations of the material. Observations of...

journal_title：Biomaterials

authors： Zoulgami M,Lucas A,Briard P,Gaudé J

更新日期：2001-07-01 00:00:00

abstract：:A simple and sensitive method for the quantitative determination of solid-supported primary and/or secondary amino groups using commercially available reagents is described. The solid supports are treated in an aqueous environment with either 2-iminothiolane (ITL) or sulpho-succinimidyl-3-(4-hydroxyphenyl)propionate (...

journal_title：Biomaterials

authors： Kakabakos SE,Tyllianakis PE,Evangelatos GP,Ithakissios DS

更新日期：1994-03-01 00:00:00

abstract：:The photodynamic activity of a carrier-sensitizer system consisting of heterotopic colloidal nanoparticles (diameter 100-1000 nm) of a cationic amphiphilic cyclodextrin, heptakis(2-omega-amino-O-oligo(ethylene oxide)-6-hexylthio)-beta-CD (SC6CDNH2) encapsulating the anionic 5,10,15,20-tetrakis(4-sulfonatophenyl)-21H,2...

journal_title：Biomaterials

authors： Sortino S,Mazzaglia A,Monsù Scolaro L,Marino Merlo F,Valveri V,Sciortino MT

更新日期：2006-08-01 00:00:00

abstract：:Peripherally inserted central catheters (PICCs) are hollow polymeric tubes that transport nutrients, blood and medications to neonates. To determine proper PICC placement, frequent X-ray imaging of neonates is performed. Because X-rays pose severe health risks to neonates, safer alternatives are needed. We hypothesize...

journal_title：Biomaterials

authors： Stevenson AT Jr,Reese LM,Hill TK,McGuire J,Mohs AM,Shekhar R,Bickford LR,Whittington AR

更新日期：2015-06-01 00:00:00

abstract：:Dextran hydrogels were formed in situ by enzymatic crosslinking of dextran-tyramine conjugates and their mechanical, swelling and degradation properties were evaluated. Two types of dextran-tyramine conjugates (M(n,dextran)=14k, M(w)/M(n)=1.45), i.e. dextran-tyramine linked by a urethane bond (denoted as Dex-TA) or by...

journal_title：Biomaterials

authors： Jin R,Hiemstra C,Zhong Z,Feijen J

更新日期：2007-06-01 00:00:00

abstract：:To explore molecular mechanism of mediation of adsorbed proteins to cell adhesion and growth on biomaterials, this study examined endothelial cell adhesion, morphology and viability on bare and titanium nitride (TiN) coated nickel titanium (NiTi) alloys and chitosan film firstly, and then identified the type and amoun...

journal_title：Biomaterials

authors： Yang D,Lü X,Hong Y,Xi T,Zhang D

更新日期：2013-07-01 00:00:00

abstract：:The peripheral nerve contains three barriers which include the blood-nerve barrier consisting of endoneurial vessels and the perineurium as well as autotypic junctions in Schwann cells. The perineurium prevents diffusion of perineurally injected drugs that can be used for selective regional pain control. It is compose...

journal_title：Biomaterials

authors： Yang S,Krug SM,Heitmann J,Hu L,Reinhold AK,Sauer S,Bosten J,Sommer C,Fromm M,Brack A,Rittner HL

更新日期：2016-03-01 00:00:00

abstract：:Nanomaterials with integrated multiple imaging and therapeutic modalities possess great potentials in accurate cancer diagnostics and enhanced therapeutic efficacy. Traditional strategies for achieving multimodality nanoplatform through one by one combination of different modalities are challenged by the complicated s...

journal_title：Biomaterials

authors： He X,Peng C,Qiang S,Xiong LH,Zhao Z,Wang Z,Kwok RTK,Lam JWY,Ma N,Tang BZ

更新日期：2020-04-01 00:00:00

abstract：:Using laser Raman microprobe spectroscopy, we have characterized the degree of hydroxylation and the state of atomic order of several natural and synthetic calcium phosphate phases, including apatite of biological (human bone, heated human bone, mouse bone, human and boar dentin, and human and boar enamel), geological...

journal_title：Biomaterials

authors： Pasteris JD,Wopenka B,Freeman JJ,Rogers K,Valsami-Jones E,van der Houwen JA,Silva MJ

更新日期：2004-01-01 00:00:00

abstract：:This work demonstrated the development of multifunctional silica nanotubes (SNT) by functionalization of their inner void and outer surface with magnetic-fluorescence nanocomposites and cationic polymers, respectively. The successful construction of BPEI-SNT was established by electron energy loss spectroscopy in conj...

journal_title：Biomaterials

authors： Namgung R,Zhang Y,Fang QL,Singha K,Lee HJ,Kwon IK,Jeong YY,Park IK,Son SJ,Kim WJ

更新日期：2011-04-01 00:00:00

abstract：:Porous silica gels with high surface areas were prepared from tetraethylothosilicate and polyacrylic acid (PAA) of high molecular weight in acidic media by a sol-gel method. PAA content and ageing temperatures were varied in order to obtain different microstructures. Samples were sintered at temperatures up to 400 deg...

journal_title：Biomaterials

authors： Gallardo J,Galliano PG,Porto López JM

更新日期：2002-11-01 00:00:00

abstract：:Long-term elution of fluoride ions has been studied for one silicate and six glass-ionomer cements over a period of some two and-a-half years. Because equilibrium was not reached, classical diffusion theory could not be applied to the process. It was postulated that two elution processes were taking place, one short-t...

journal_title：Biomaterials

authors： Tay WM,Braden M

更新日期：1988-09-01 00:00:00

abstract：:We report here a thermal decomposition approach to the synthesis of water-soluble superparamagnetic manganese ferrite (MnFe(2)O(4)) nanoparticles (NPs) for magnetic resonance (MR) imaging applications. In this approach, tetraethylene glycol was utilized as a coordination and stabilization agent, rendering the NPs wate...

journal_title：Biomaterials

authors： Yang H,Zhang C,Shi X,Hu H,Du X,Fang Y,Ma Y,Wu H,Yang S

更新日期：2010-05-01 00:00:00

abstract：:Construction of bio-mimetic well-organized three-dimensional (3D) tissue with various cells in vitro is one of the ultimate goals of tissue engineering. In particular, fabrication of vasculature in 3D tissue is one of the most important tasks in tissue engineering, because a vascular network is indispensable for almos...

journal_title：Biomaterials

authors： Muraoka M,Shimizu T,Itoga K,Takahashi H,Okano T

更新日期：2013-01-01 00:00:00

abstract：:To study the effect of ionizable functional groups on the adhesion of leucocytes to surfaces, both poly(ethyleneimine) and poly(acrylic acid) were immobilized on polyurethane films, resulting in the introduction of amine and carboxylic acid groups, respectively. This was confirmed by contact angle measurements and XPS...

journal_title：Biomaterials

authors： Bruil A,Terlingen JG,Beugeling T,van Aken WG,Feijen J

更新日期：1992-01-01 00:00:00

abstract：:The clinical application of cancer radiotherapy is critically impeded by hypoxia-induced radioresistance, insufficient DNA damage, and multiple DNA repair mechanisms. Herein we demonstrate a dual-hyperthermia strategy to potentiate radiotherapy by relieving tumor hypoxia and preventing irradiation-induced DNA damage r...

journal_title：Biomaterials

authors： Li Q,Hang L,Jiang W,Dou J,Xiao L,Tang X,Yao Y,Wang Y

更新日期：2020-10-01 00:00:00

abstract：:Non-linear optical microscopy methods can characterize over time multiple functional properties of engineered tissues during development. Here, we demonstrate how the combined use of third-harmonic generation (THG) and two-photon excited fluorescence (2PEF) imaging can provide direct quantitative biomarkers of adipoge...

journal_title：Biomaterials

authors： Chang T,Zimmerley MS,Quinn KP,Lamarre-Jouenne I,Kaplan DL,Beaurepaire E,Georgakoudi I

更新日期：2013-11-01 00:00:00

abstract：:Hydrogels produced from self-assembling peptides and peptide derivatives are being investigated as synthetic extracellular matrices for defined cell culture substrates and scaffolds for regenerative medicine. In many cases, however, they are less stiff than the tissues and extracellular matrices they are intended to m...

journal_title：Biomaterials

authors： Jung JP,Jones JL,Cronier SA,Collier JH

更新日期：2008-05-01 00:00:00

abstract：:A synthetic process for obtaining high-molecular-weight block copolymers containing poly(lactic-glycolic acid) and poly(ethylene glycol) segments has been established. This process involves the reaction of poly(ethylene glycols) with phosgene, followed by polycondensation of the resulting alpha, omega-bis(chloroformat...

journal_title：Biomaterials

authors： Ferruti P,Penco M,D'Addato P,Ranucci E,Deghenghi R

更新日期：1995-12-01 00:00:00

abstract：:Intercellular interactions in the cell microenvironment play a critical role in determining cell fate, but the effects of these interactions on pathways governing human embryonic stem cell (hESC) behavior have not been fully elucidated. We and others have previously reported that 3-D culture of hESCs affects cell fate...

journal_title：Biomaterials

authors： Azarin SM,Lian X,Larson EA,Popelka HM,de Pablo JJ,Palecek SP

更新日期：2012-03-01 00:00:00

abstract：:Solid tissues in the body possess a range of stiffness and provide cells with an instructive microenvironment. Scaffolds in tissue engineering should be rationally designed to become an adhesion substrate friendly to cells. Schwann cells are the principal glial cell in the peripheral nervous system and used as support...

journal_title：Biomaterials

authors： Gu Y,Ji Y,Zhao Y,Liu Y,Ding F,Gu X,Yang Y

更新日期：2012-10-01 00:00:00

abstract：:In order to increase the functionality of islets encapsulated in a biohybrid artificial pancreas (BAP), it was proposed that co-encapsulation with insulinotropic agents would improve insulin secretion from islets. To prevent agents from leaking out, conjugation with high-molecular-weight polymers was inevitable. In th...

journal_title：Biomaterials

authors： Kim S,Wan Kim S,Bae YH

更新日期：2005-06-01 00:00:00

abstract：:Dual-functional liposomes with pH-responsive cell-penetrating peptide (CPP) and active targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of synthetic tumor pH-triggered CPPs rich in arginines and histidines were screened by comparing tumor cellular uptake efficiency at pH 6.4 wi...

journal_title：Biomaterials

authors： Jiang T,Zhang Z,Zhang Y,Lv H,Zhou J,Li C,Hou L,Zhang Q

更新日期：2012-12-01 00:00:00

abstract：:Tissue-engineering technology employing genetically-modified mesenchymal stem cells combined with proper scaffolds represents a promising strategy for bone regeneration. Elucidating the underlying mechanisms that govern the osteogenesis of mesenchymal stem cells will give deeper insights into the regulatory patterns, ...

journal_title：Biomaterials

authors： Xie Q,Wang Z,Zhou H,Yu Z,Huang Y,Sun H,Bi X,Wang Y,Shi W,Gu P,Fan X

更新日期：2016-01-01 00:00:00

abstract：:The abundant extracellular matrix (ECM) in the glioma microenvironment play a critical role in the maintenance of glioma morphology, glioma cells differentiation and proliferation, but little has been done to understand the feasibility of ECM as the therapeutic target for glioma therapy. In this study, a drug delivery...

journal_title：Biomaterials

authors： Zhang B,Shen S,Liao Z,Shi W,Wang Y,Zhao J,Hu Y,Yang J,Chen J,Mei H,Hu Y,Pang Z,Jiang X

更新日期：2014-04-01 00:00:00

abstract：:In this study, we used deoxyribozyme (DNAzyme) functionalized gold nanoparticles (AuNPs) to catalytically silence tumor necrosis factor-α (TNF-α) in vivo as a potential therapeutic for myocardial infarction (MI). Using primary macrophages as a model, we demonstrated 50% knockdown of TNF-α, which was not attainable usi...

journal_title：Biomaterials

authors： Somasuntharam I,Yehl K,Carroll SL,Maxwell JT,Martinez MD,Che PL,Brown ME,Salaita K,Davis ME

更新日期：2016-03-01 00:00:00

abstract：:Barium titanate (BaTiO3; BTO) is ferroelectric and piezoelectric after poling treatment. In this study, the bioactivity of BTO was investigated after a poling treatment by examining the formation of crystal growth on specimen surfaces in vitro. Negatively charged BTO surfaces showed calcium phosphate (Ca-P) crystal gr...

journal_title：Biomaterials

authors： Park YJ,Hwang KS,Song JE,Ong JL,Rawls HR

更新日期：2002-09-01 00:00:00