A self-setting single-component calcium phosphate cement.

abstract：:Peripheral nerve injuries often lead to incomplete recovery and contribute to significant disability to approximately 360,000 people in the USA each year. Stem cell therapy holds significant promise for peripheral nerve regeneration, but maintenance of stem cell viability and differentiation potential in vivo are stil...

journal_title：Biomaterials

authors： Du J,Zhen G,Chen H,Zhang S,Qing L,Yang X,Lee G,Mao HQ,Jia X

更新日期：2018-10-01 00:00:00

abstract：:Low back pain is one of the most common medical conditions in the Western world. Disc degeneration, an inevitable process of aging, of variable rate and degree, is one of the major causes of low back pain. Currently, there are two major surgical interventions for treating conditions related to the degenerative disc: d...

journal_title：Biomaterials

authors： Bao QB,McCullen GM,Higham PA,Dumbleton JH,Yuan HA

更新日期：1996-06-01 00:00:00

abstract：:We report on the fabrication of multifunctional polymeric unimolecular micelles as an integrated platform for cancer targeted drug delivery and magnetic resonance imaging (MRI) contrast enhancement under in vitro and in vivo conditions. Starting from a fractionated fourth-generation hyperbranched polyester (Boltorn H4...

journal_title：Biomaterials

authors： Li X,Qian Y,Liu T,Hu X,Zhang G,You Y,Liu S

更新日期：2011-09-01 00:00:00

abstract：:The poor biocompatibility of metallic coronary stents which leads to un-satisfying restenosis rates is mainly caused by contact activation of blood cells, smooth muscle cells and endothelial cells. Mimicking a metal surface with a biocompatible coating that actively suppresses mechanisms leading to restenosis may over...

journal_title：Biomaterials

authors： Lahann J,Klee D,Pluester W,Hoecker H

更新日期：2001-04-01 00:00:00

abstract：:In the present study, the effects of a calcium magnesium silicate bioactive ceramic (akermanite) on proliferation and osteoblastic differentiation of human bone marrow stromal cells (hBMSC) have been investigated and compared with the classical ceramic (beta-tricalcium phosphate, beta-TCP). Akermanite and beta-TCP dis...

journal_title：Biomaterials

authors： Sun H,Wu C,Dai K,Chang J,Tang T

更新日期：2006-11-01 00:00:00

abstract：:The performance of implantable biomaterials derived from decellularized tissue, including encouraging results with skeletal muscle, suggests that the extracellular matrix (ECM) derived from native tissue has promising regenerative potential. Yet, the supply of biomaterials derived from donated tissue will always be li...

journal_title：Biomaterials

authors： Hurd SA,Bhatti NM,Walker AM,Kasukonis BM,Wolchok JC

更新日期：2015-05-01 00:00:00

abstract：:Two new formulations of bioactive glasses were used as coatings on titanium alloy (TiAl6V4) implants for prosthetic applications in the orthopaedic field. The biocompatibility of these bioglasses, as well as their osteoconductive properties, were assessed by employing primary cultures of human osteoblasts. A nonbioact...

journal_title：Biomaterials

authors： Oliva A,Salerno A,Locardi B,Riccio V,Della Ragione F,Iardino P,Zappia V

更新日期：1998-06-01 00:00:00

abstract：:Samples of linear (additionally crosslinked) p(HEMA) with different amounts of fibrillar collagen were implanted into the popliteal region of rats. After 3 month, the implanted materials were harvested and examined by SEM. The implants underwent marked structural or morphological changes. While the fibrillar collagen ...

journal_title：Biomaterials

authors： Stol M,Cífková I,Tyrácková V,Adam M

更新日期：1991-07-01 00:00:00

abstract：:Arterial catheterization is one of the most frequently performed inpatient diagnostic and therapeutic procedures in the development countries. Complications may occur after any catheterization from inadequate hemostasis, particularly in the setting of aggressive anticoagulation. This study suggests that microcrystalli...

journal_title：Biomaterials

authors： Hoekstra A,Struszczyk H,Kivekäs O

更新日期：1998-08-01 00:00:00

abstract：:The use of non-viral nanoparticulate systems for the delivery of therapeutic agents is receiving considerable attention for medical and pharmaceutical applications. This increasing interest results from the fact that these systems can be designed to meet specific physicochemical requirements, and they display low toxi...

journal_title：Biomaterials

authors： Chellat F,Merhi Y,Moreau A,Yahia L

更新日期：2005-12-01 00:00:00

abstract：:Stimuli-responsive nanoparticles hold great promise for drug delivery to improve the safety and efficacy of cancer therapy. One of the most investigated stimuli-responsive strategies is to induce drug release by heating with laser, ultrasound, or electromagnetic field. More recently, cryosurgery (also called cryothera...

journal_title：Biomaterials

authors： Wang H,Agarwal P,Liang Y,Xu J,Zhao G,Tkaczuk KHR,Lu X,He X

更新日期：2018-10-01 00:00:00

abstract：:Palladium additions to a dispersed phase high-copper amalgam have been shown recently to suppress markedly the eta' (Cu6Sn5) concentration and decrease creep. A detailed study of the dental and 24 h creep for Pd containing high-copper amalgams and six commercial controls as a function of applied temperature and stress...

journal_title：Biomaterials

authors： Greener EH,Chung KH,Lin JH

更新日期：1988-05-01 00:00:00

abstract：:Electrically conducting polymers hold promise for developing advanced neuroprostheses, bionic systems and neural repair devices. Among them, poly(3, 4-ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) exhibits superior physicochemical properties but biocompatibility issues have limited its use. We d...

journal_title：Biomaterials

authors： Collazos-Castro JE,Polo JL,Hernández-Labrado GR,Padial-Cañete V,García-Rama C

更新日期：2010-12-01 00:00:00

abstract：:Pancreatic cancer has the worst prognosis of all cancers due to disease aggressiveness and paucity of early detection platforms. We developed biomaterial scaffolds that recruit metastatic tumor cells and reflect the immune dysregulation of native metastatic sites. While this platform has shown promise in orthotopic br...

journal_title：Biomaterials

authors： Bushnell GG,Orbach SM,Ma JA,Crawford HC,Wicha MS,Jeruss JS,Shea LD

更新日期：2020-12-23 00:00:00

abstract：:Co-polymeric hydrogels of collagen and poly(hydroxyethyl methacrylate) (pHEMA) were prepared using an ammonium persulphate-sodium metabisulphite redox initiation technique. Fluorescein isothiocyanate (FITC)-labelled bovine serum albumin (BSA) was entrapped into these hydrogels. These gels were modified differently by ...

journal_title：Biomaterials

authors： Rao JK,Ramesh DV,Rao KP

更新日期：1994-04-01 00:00:00

abstract：:In our previous study, a three-dimensional zein porous scaffold with a compressive Young's modulus of up to 86.6+/-19.9 MPa and a compressive strength of up to 11.8+/-1.7 MPa was prepared, and was suitable for culture of mesenchymal stem cells (MSCs) in vitro. In this study, we examined its tissue compatibility in a r...

journal_title：Biomaterials

authors： Wang HJ,Gong SJ,Lin ZX,Fu JX,Xue ST,Huang JC,Wang JY

更新日期：2007-09-01 00:00:00

abstract：:The optimal ratio of the polycation's amine to DNA phosphate group (N:P) for efficient polymer-based transfection always employs excess polycation versus DNA. Most of the excess polycation remains free in solution, unassociated with the polyplexes, but is essential for efficient transfection. The mechanism by which ex...

journal_title：Biomaterials

authors： Thibault M,Astolfi M,Tran-Khanh N,Lavertu M,Darras V,Merzouki A,Buschmann MD

更新日期：2011-07-01 00:00:00

abstract：:Three one-week controlled-release methadone formulations: polylactic acid microspheres (F-PLA) and poly(lactide-co-glycolide) microspheres (F-PLGA) with 24 and 30% methadone content, respectively, and an implant of 50:50 poly(lactide-co-glycolide): methadone, were evaluated in vitro and in vivo. The implant released t...

journal_title：Biomaterials

authors： Negrin CM,Delgado A,Llabrés M,Evora C

更新日期：2001-03-01 00:00:00

abstract：:Nickel-titanium (NiTi, nitinol) shape memory alloy was nitrided using an original powder immersion reaction assisted coating (PIRAC) method in order to modify its surface properties. PIRAC nitriding method is based on annealing the samples in the atmosphere of highly reactive nitrogen supplied by decomposition of unst...

journal_title：Biomaterials

authors： Starosvetsky D,Gotman I

更新日期：2001-07-01 00:00:00

abstract：:Two kinds of layered atelocollagen materials cross-linked with hexamethylene diisocyanate (HMDIC), starch dialdehyde and glyoxal were enzymatically treated by bacterial collagenase. Evaluating collagenase digestion assay for these material showed progressive differences, particularly in the group of samples cross-link...

journal_title：Biomaterials

authors： Vizárová K,Bakos D,Rehákova M,Petríkova M,Panáková E,Koller J

更新日期：1995-11-01 00:00:00

abstract：:In order to clarify the role of a primer on the adhesion between dental precious metals and resin, surface-enhanced Raman scattering (SERS) technique has been applied to the structural analysis of the adhesive monomer, 6-(N-(4-vinylbenzyl)propylamino)-1,3,5-triazine-2, 4-dithione (VBATDT) adsorbed on colloidal Au surf...

journal_title：Biomaterials

authors： Suzuki M,Fujishima A,Miyazaki T,Hisamitsu H,Kojima K,Kadoma Y

更新日期：1999-05-01 00:00:00

abstract：:The main challenge for neural progenitor cell (NPC)-mediated repair of spinal cord injury (SCI) is lack of favorable environment to direct its differentiation towards neurons rather than glial cells. The myelin associated inhibitors have been demonstrated to promote NPC differentiation into glial lineage. Herein, to i...

journal_title：Biomaterials

authors： Li X,Xiao Z,Han J,Chen L,Xiao H,Ma F,Hou X,Li X,Sun J,Ding W,Zhao Y,Chen B,Dai J

更新日期：2013-07-01 00:00:00

abstract：:In order to overcome the problem of rapid clearance of the polysaccharide hyaluronic acid (Hyal) in the treatment of osteoarthritis (OA), a 50% cross-linked Hyal hydrogel (Hyal 50%) was synthesised. The 50% refers to the amount of COOH groups of the polysaccharide involved in the cross-linking reaction. i.e. 50% of th...

journal_title：Biomaterials

authors： Barbucci R,Lamponi S,Borzacchiello A,Ambrosio L,Fini M,Torricelli P,Giardino R

更新日期：2002-12-01 00:00:00

abstract：:Cancer therapeutics are developed through extensive screening; however, many therapeutics evaluated with 2D in vitro cultures during pre-clinical trials suffer from lower efficacy in patients. Replicating the in vivo tumor microenvironment in vitro with three-dimensional (3D) porous scaffolds offers the possibility of...

journal_title：Biomaterials

authors： Florczyk SJ,Wang K,Jana S,Wood DL,Sytsma SK,Sham J,Kievit FM,Zhang M

更新日期：2013-12-01 00:00:00

abstract：:The clinical application of cancer radiotherapy is critically impeded by hypoxia-induced radioresistance, insufficient DNA damage, and multiple DNA repair mechanisms. Herein we demonstrate a dual-hyperthermia strategy to potentiate radiotherapy by relieving tumor hypoxia and preventing irradiation-induced DNA damage r...

journal_title：Biomaterials

authors： Li Q,Hang L,Jiang W,Dou J,Xiao L,Tang X,Yao Y,Wang Y

更新日期：2020-10-01 00:00:00

abstract：:The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of the nucleus pulposus (NP) was investigated. The specific hypothesis under study was that the cationic chitosan would form an idea...

journal_title：Biomaterials

authors： Roughley P,Hoemann C,DesRosiers E,Mwale F,Antoniou J,Alini M

更新日期：2006-01-01 00:00:00

abstract：:An appropriate method to bind extracellular matrix (ECM) proteins and growth factors using advanced protein engineering techniques has the potential to enhance cell proliferation and differentiation for tissue regeneration and repair. In this study we developed a method to co-immobilize non-covalently an ECM protein t...

journal_title：Biomaterials

authors： Assal Y,Mie M,Kobatake E

更新日期：2013-04-01 00:00:00

abstract：:Following our recent report of attractive antibacterial properties of a designed amphiphilic peptide, A(9)K, we have investigated its antitumor activities by examining the modes of its action against different mammalian cell types. The peptide strongly inhibited the growth of cancerous HeLa cells and human promyelocyt...

journal_title：Biomaterials

authors： Xu H,Chen CX,Hu J,Zhou P,Zeng P,Cao CH,Lu JR

更新日期：2013-04-01 00:00:00

abstract：:Hydrogels are frequently employed as medical device biomaterials due to their advantageous biological properties, e.g. resistance to infection and encrustation, biocompatibility; however, their poor mechanical properties generally limit the scope of application to coatings of medical devices. To address this limitatio...

journal_title：Biomaterials

authors： Jones DS,McLaughlin DW,McCoy CP,Gorman SP

更新日期：2005-05-01 00:00:00

abstract：:Poly(L-lactide) (PLLA) with an extremely high molecular weight (Mv up to 1 X 10(6)) was synthesized at a low catalyst concentration (0.015 wt%) and temperatures between 100-110 degrees C. Besides good mechanical properties the as-polymerized PLLA exhibited a microporous structure. Plates and screws of this material we...

journal_title：Biomaterials

authors： Leenslag JW,Pennings AJ,Bos RR,Rozema FR,Boering G

更新日期：1987-01-01 00:00:00