The origin of rare alkali metals in geothermal fluids of southern Tibet, China: A silicon isotope perspective.

abstract：:In this paper, we investigate the magnetic behavior of a single-walled hexagonal spin-1 Ising nanotube by using the effective field theory (EFT) with correlations and the differential operator technique (DOT). The system consists of six long legs distributed parallel to each other on a hexagonal basis. Within each cha...

journal_title：Scientific reports

authors： ElMaddahi Z,El Hafidi MY,El Hafidi M

更新日期：2019-08-26 00:00:00

abstract：:This paper studies the social acceptability and feasibility of a focused protection strategy against coronavirus disease 2019 (COVID-19). We propose a control scheme to develop herd immunity while satisfying the following two basic requirements for a viable policy option. The first requirement is social acceptability:...

journal_title：Scientific reports

authors： Akamatsu T,Nagae T,Osawa M,Satsukawa K,Sakai T,Mizutani D

更新日期：2021-01-21 00:00:00

abstract：:αβ T cells respond to peptide epitopes presented by major histocompatibility complex (MHC) molecules. The role of T cell receptor (TCR) germline complementarity determining regions (CDR1 and 2) in MHC restriction is not well understood. Here, we examine T cell development, MHC restriction and antigen recognition where...

journal_title：Scientific reports

authors： Attaf M,Holland SJ,Bartok I,Dyson J

更新日期：2016-10-24 00:00:00

abstract：:Telomerase is a ribonucleoprotein enzyme, which maintains genome integrity in eukaryotes and ensures continuous cellular proliferation. Telomerase holoenzyme from the thermotolerant yeast Hansenula polymorpha, in addition to the catalytic subunit (TERT) and telomerase RNA (TER), contains accessory proteins Est1 and Es...

journal_title：Scientific reports

authors： Shepelev NM,Mariasina SS,Mantsyzov AB,Malyavko AN,Efimov SV,Petrova OA,Rodina EV,Zvereva MI,Dontsova OA,Polshakov VI

更新日期：2020-07-06 00:00:00

abstract：:Loss of miR-200c is correlated to advanced cancer-subtypes due to increased EMT and decreased treatment efficacy by chemotherapeutics. As miRNAs regulate a multitude of targets, the analysis of differentially expressed proteins upon a genomic knock-out (KO) is of interest. In this study, we generated a TALENs KO of mi...

journal_title：Scientific reports

authors： Ljepoja B,García-Roman J,Sommer AK,Fröhlich T,Arnold GJ,Wagner E,Roidl A

更新日期：2018-05-02 00:00:00

abstract：:The present work aimed to investigate the activities and underlying mechanisms of dioscin against alcoholic liver fibrosis (ALF). In vivo liver fibrosis in mice was induced by an alcoholic liquid diet, and in vitro studies were performed on activated HSC-T6 and LX2 cells treated with lipopolysaccharide. Our results sh...

journal_title：Scientific reports

authors： Liu M,Xu Y,Han X,Yin L,Xu L,Qi Y,Zhao Y,Liu K,Peng J

更新日期：2015-12-10 00:00:00

abstract：:Implantable 3D engineered vascular tissue constructs can be formed by co-culturing endothelial and fibroblast cells on macroporous scaffolds. Here we show that these constructs can be used for studying the dynamics of neovascular formation in-vitro by a combination of live confocal imaging and an array of image proces...

journal_title：Scientific reports

authors： Blinder YJ,Freiman A,Raindel N,Mooney DJ,Levenberg S

更新日期：2015-12-09 00:00:00

abstract：:Vertical mixing modulates nutrient dynamics in lakes. However, surface warming reduces the range of vertical mixing and the probability of full circulation events. Important consequences of reduced vertical mixing include the sequestration of phosphorus (P) within a stagnant zone and the promotion of oligotrophication...

journal_title：Scientific reports

authors： Lau MP,Valerio G,Pilotti M,Hupfer M

更新日期：2020-07-31 00:00:00

abstract：:Maize is rapidly replacing traditionally cultivated dual purpose crops of South Asia, primarily due to the better economic remuneration. This has created an impetus for improving maize for both grain productivity and stover traits. Molecular techniques can largely assist breeders in determining approaches for effectiv...

journal_title：Scientific reports

authors： Vinayan MT,Seetharam K,Babu R,Zaidi PH,Blummel M,Nair SK

更新日期：2021-01-12 00:00:00

abstract：:Extracellular adenosine, generated via the concerted action of CD39 and CD73, contributes to T-cell differentiation and function. Adenosine concentrations are furthermore influenced by adenosine deaminase binding protein CD26. Because aberrant T-cell phenotypes had been reported in anti-neutrophil cytoplasmic auto-ant...

journal_title：Scientific reports

authors： Kling L,Benck U,Breedijk A,Leikeim L,Heitzmann M,Porubsky S,Krämer BK,Yard BA,Kälsch AI

更新日期：2017-09-15 00:00:00

abstract：:Scleroderma is a refractory autoimmune skin fibrotic disorder. Alterations of microRNAs in lesional skin could be a new approach to treating the disease. Here, we found that expression of miR-155 was up regulated in lesional skin tissue from patients with either systemic or localized scleroderma, and correlated with f...

journal_title：Scientific reports

authors： Yan Q,Chen J,Li W,Bao C,Fu Q

更新日期：2016-02-01 00:00:00

abstract：:Whether the clinical trial treatment effect of urate-lowering therapy (ULT) in patient with chronic kidney disease (CKD) is generalizable to real-word settings is unclear. This study aimed to compare febuxostat with allopurinol for uric acid reduction and renal protection in patients with CKD. Adult CKD patients newly...

journal_title：Scientific reports

authors： Peng YL,Tain YL,Lee CT,Yang YH,Huang YB,Wen YH,Hsu CN

更新日期：2020-07-01 00:00:00

abstract：:Recurrent genetic mutations occur in acute myeloid leukemia (AML) and have been incorporated into risk stratification to predict the prognoses of AML patients. The bone marrow microenvironment plays a critical role in the development and progression of AML. However, the characteristics of the genetic mutation-associat...

journal_title：Scientific reports

authors： Wang J,Dao FT,Yang L,Qin YZ

更新日期：2020-11-04 00:00:00

abstract：:The concept of multiscale architectured materials is established using composition and grain size gradients. Composition-gradient nanostructured materials are produced from coarse grained interstitial free steels via carburization and high-pressure torsion. Quantitative analyses of the dislocation density using X-ray ...

journal_title：Scientific reports

authors： Kang JY,Kim JG,Park HW,Kim HS

更新日期：2016-05-27 00:00:00

abstract：:In the last years, great advances have been made in therapies based in cold atmospheric plasmas (CAP). CAP generate reactive oxygen and nitrogen species (RONS) which can be transferred to liquids. These CAP activated liquids display the same biological efficacy (i.e. on killing cancer cells) as CAP themselves, opening...

journal_title：Scientific reports

authors： Labay C,Hamouda I,Tampieri F,Ginebra MP,Canal C

更新日期：2019-11-06 00:00:00

abstract：:In this report, we propose and demonstrate an air-mode photonic crystal ring resonator (PhCRR) on silicon-on-insulator platform. Air mode is utilized to confine the optical field into photonic crystal (PhC) air holes, which is confirmed by the three-dimensional finite-difference time-domain simulation. PhCRR structure...

journal_title：Scientific reports

authors： Gao G,Zhang Y,Zhang H,Wang Y,Huang Q,Xia J

更新日期：2016-01-28 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive immune-mediated joint deterioration. Current treatments are not antigen specific and are associated with various adverse. We have previously demonstrated that tolerogenic dendritic cells (Tol-DC) are potent antigen-specific immune regulato...

journal_title：Scientific reports

authors： Li R,Zhang Y,Zheng X,Peng S,Yuan K,Zhang X,Min W

更新日期：2017-02-23 00:00:00

abstract：:Local and systemic oxidative stress in intraocular pressure (IOP) elevation and optic nerve damage may be involved in the pathogenesis of glaucoma. We reported previously that a lower level of systemic antioxidative capacity is associated with IOP elevation in open-angle glaucoma (OAG). We assessed the correlation bet...

journal_title：Scientific reports

authors： Tanito M,Kaidzu S,Takai Y,Ohira A

更新日期：2016-05-11 00:00:00

abstract：:Insects are ectothermal animals that are constrained in their survival and reproduction by external temperature fluctuations which require either active avoidance of or movement towards a given heat source. In Drosophila, different thermoreceptors and neurons have been identified that mediate temperature sensation to ...

journal_title：Scientific reports

authors： Buhl E,Kottler B,Hodge JJL,Hirth F

更新日期：2021-01-08 00:00:00

abstract：:Neovascularization of the erectile tissue emerges as a beneficial curative approach to treat erectile dysfunction (ED). Here we for the first time report the unexpected role of vasohibin-1 (VASH1), mainly known as an anti-angiogenic factor, in restoring erectile function in diabetic mice. A diabetic patient has lower ...

journal_title：Scientific reports

authors： Song KM,Kim WJ,Choi MJ,Kwon KD,Limanjaya A,Ghatak K,Ock J,Yin GN,Sato Y,Hong SS,Ryu JK,Suh JK

更新日期：2021-01-13 00:00:00

abstract：:As a class, 'BET' inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, especially super-enhancers, to inhibit gene transcription. As such, BET inhibitors may be useful ...

journal_title：Scientific reports

authors： Gibbons HR,Mi DJ,Farley VM,Esmond T,Kaood MB,Aune TM

更新日期：2019-07-16 00:00:00

abstract：:Although stenting of non-branched arterial segments has acceptable clinical outcomes, in-stent restenosis (ISR) and stent thrombosis remain clinically significant issues for vascular bifurcations (15-28% restenosis). Local fluid and solid stresses appear to play an important role in restenosis and thrombosis. The comb...

journal_title：Scientific reports

authors： Chen HY,Chatzizisis YS,Louvard Y,Kassab GS

更新日期：2020-06-15 00:00:00

abstract：:Despite extensive research on various types of meditation, research on the neural correlates of religious chanting is in a nascent stage. Using multi-modal electrophysiological and neuroimaging methods, we illustrate that during religious chanting, the posterior cingulate cortex shows the largest decrease in eigenvect...

journal_title：Scientific reports

authors： Gao J,Leung HK,Wu BWY,Skouras S,Sik HH

更新日期：2019-03-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Hegde A,Suresh S,Mitra R

更新日期：2020-10-06 00:00:00

abstract：:Animal models are extensively used to evaluate the in vivo functionality of novel drug delivery systems (DDS). However, many variations likely exist in vivo between the animals and human physiological environment that significantly alter results obtained with animal models relative to human system. To date, it is not ...

journal_title：Scientific reports

authors： Namdee K,Carrasco-Teja M,Fish MB,Charoenphol P,Eniola-Adefeso O

更新日期：2015-06-26 00:00:00

abstract：:Ischemic stroke and diabetes are vascular risk factors for the development of impaired memory such as dementia and/or Alzheimer's disease. Clinical studies have demonstrated that minor striatal ischemic lesions in combination with β-amyloid (Aβ) load are critical in generating cognitive deficits. These cognitive defic...

journal_title：Scientific reports

authors： Amtul Z,Hill DJ,Arany EJ,Cechetto DF

更新日期：2018-03-23 00:00:00

abstract：:Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...

journal_title：Scientific reports

authors： Syaifudin M,Bekaert M,Taggart JB,Bartie KL,Wehner S,Palaiokostas C,Khan MGQ,Selly SC,Hulata G,D'Cotta H,Baroiller JF,McAndrew BJ,Penman DJ

更新日期：2019-09-10 00:00:00

abstract：:Sea buckthorn (Hippophae Rhamnoides L.) is an important source of bioactive compounds such as: antioxidants, vitamins, fatty acids, amino acids, and minerals. Sea buckthorn leaves extracts have been proved to have anti-microbial, antioxidant, anti-inflammatory, and anti-viral properties. In this paper, the extraction ...

journal_title：Scientific reports

authors： Asofiei I,Calinescu I,Trifan A,Gavrila AI

更新日期：2019-08-19 00:00:00

abstract：:Paedomorphosis and metamorphosis are two major developmental processes that characterize the evolution of complex life cycles in many lineages. Whereas these processes were fixed in some taxa, they remained facultative in others, with alternative phenotypes expressed in the same populations. From a genetic perspective...

journal_title：Scientific reports

authors： Oromi N,Michaux J,Denoël M

更新日期：2016-08-18 00:00:00

abstract：:Bacillus widely exists in wet natural environment such as soil, water and air, and is often studied as one of representative microorganisms for microbiologically influenced corrosion(MIC) research. In this paper, the growth curve of Bacillus subtilis isolated from marine environment was determined by turbidimetry and ...

journal_title：Scientific reports

authors： Wang YS,Liu L,Fu Q,Sun J,An ZY,Ding R,Li Y,Zhao XD

更新日期：2020-04-01 00:00:00