A proteomic analysis of an in vitro knock-out of miR-200c.

abstract：:In the present work, an attempt has been made to synthesize the 1,2,3-triazole derivatives resulting from the click reaction, in a mild and green environment using the new copper(II)-coated magnetic core-shell nanoparticles Fe3O4@SiO2 modified by isatoic anhydride. The structure of the catalyst has been determined by ...

journal_title：Scientific reports

authors： Rajabi-Moghaddam H,Naimi-Jamal MR,Tajbakhsh M

更新日期：2021-01-22 00:00:00

abstract：:GABAergic and glutamatergic dysfunction in the dorsolateral prefrontal cortex (DLPFC) are thought to be the core pathophysiological mechanisms of schizophrenia. Recently, we have established a method to index these functions from the DLPFC using the paired transcranial magnetic stimulation (TMS) paradigms of short int...

journal_title：Scientific reports

authors： Noda Y,Barr MS,Zomorrodi R,Cash RFH,Farzan F,Rajji TK,Chen R,Daskalakis ZJ,Blumberger DM

更新日期：2017-12-06 00:00:00

abstract：:The ubiquitously expressed aryl hydrocarbon receptor (AhR) induces drug metabolizing enzymes as well as regulators of cell growth, differentiation and apoptosis. Certain AhR ligands promote atherosclerosis, an age-associated vascular disease. Therefore, we investigated the role of AhR in vascular functionality and agi...

journal_title：Scientific reports

authors： Eckers A,Jakob S,Heiss C,Haarmann-Stemmann T,Goy C,Brinkmann V,Cortese-Krott MM,Sansone R,Esser C,Ale-Agha N,Altschmied J,Ventura N,Haendeler J

更新日期：2016-01-21 00:00:00

abstract：:Scanning micro-mirror actuators are silicon-based oscillatory micro-electro-mechanical systems (MEMS). They enable laser distance measurements for automotive LIDAR applications as well as projection modules for the consumer market. For MEMS applications, the geometric structure is typically designed to serve a number ...

journal_title：Scientific reports

authors： Nabholz U,Schatz F,Mehner JE,Degenfeld-Schonburg P

更新日期：2019-03-08 00:00:00

abstract：:Although the cause of Alzheimer's disease (AD) is unknown, glial-induced neuroinflammation is an early symptom. Familial AD is caused by increases in amyloid-beta (Aβ) peptide, particularly soluble oligomeric (oAβ), considered a proximal neurotoxin and neuroinflammatory stimuli. APOE4, a naturally occurring genotype o...

journal_title：Scientific reports

authors： Ghura S,Tai L,Zhao M,Collins N,Che CT,Warpeha KM,LaDu MJ

更新日期：2016-07-07 00:00:00

abstract：:SLC30A2 encodes a zinc (Zn) transporter (ZnT2) that imports Zn into vesicles in highly-specialized secretory cells. Numerous mutations and non-synonymous variants in ZnT2 have been reported in humans and in breastfeeding women; ZnT2 variants are associated with abnormally low milk Zn levels and can lead to severe infa...

journal_title：Scientific reports

authors： Lee S,Zhou Y,Gill DL,Kelleher SL

更新日期：2018-02-23 00:00:00

abstract：:Paraquat (PQ) is a non-selective contact herbicide, and acute PQ poisoning has a high mortality. The aim of the present study is to evaluate the prognostic value of hematological parameters in patients with acute PQ poisoning. We retrospectively reviewed the records of patients with acute PQ poisoning from January 201...

journal_title：Scientific reports

authors： Zhou DC,Zhang H,Luo ZM,Zhu QX,Zhou CF

更新日期：2016-11-08 00:00:00

abstract：:We have prepared and tested a new surface enhanced Raman scattering (SERS) substrate based on self-assembled graphitic sheets to detect bisphenol A (BPA) in plastic consumer goods. Transmission electron microscopy (TEM) and atomic-force microscopy (AFM) were used to characterize the structure of the graphitic sheets a...

journal_title：Scientific reports

authors： Lin PY,Hsieh CW,Hsieh S

更新日期：2017-12-01 00:00:00

abstract：:Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is based on single-mo...

journal_title：Scientific reports

authors： Fricke F,Beaudouin J,Eils R,Heilemann M

更新日期：2015-09-11 00:00:00

abstract：:The triboelectric nanogenerator (TENG) is a promising device in energy harvesting and self-powered sensing. In this work, we demonstrate a magnetic-assisted TENG, utilizing the magnetic force for electric generation. Maximum power density of 541.1 mW/m(2) is obtained at 16.67 MΩ for the triboelectric part, while the e...

journal_title：Scientific reports

authors： Han M,Zhang XS,Sun X,Meng B,Liu W,Zhang H

更新日期：2014-04-28 00:00:00

abstract：:We propose a hybrid sequential prediction model called "Deep Sequence", integrating radiomics-engineered imaging features, demographic, and visual factors, with a recursive neural network (RNN) model in the same platform to predict the risk of exudation within a future time-frame in non-exudative AMD eyes. The propose...

journal_title：Scientific reports

authors： Banerjee I,de Sisternes L,Hallak JA,Leng T,Osborne A,Rosenfeld PJ,Gregori G,Durbin M,Rubin D

更新日期：2020-09-22 00:00:00

abstract：:Nitrogen-Vacancy (NV) centers in diamond are promising solid-state quantum emitters that can be utilized for photonic quantum applications. Various diamond nanophotonic devices have been fabricated for efficient extraction of single photons emitted from NV centers to a single guided mode. However, for constructing sca...

journal_title：Scientific reports

authors： Yonezu Y,Wakui K,Furusawa K,Takeoka M,Semba K,Aoki T

更新日期：2017-10-11 00:00:00

abstract：:The need for sensitive, robust, portable, and inexpensive biosensing platforms is of significant interest in clinical applications for disease diagnosis and treatment monitoring at the point-of-care (POC) settings. Rapid, accurate POC diagnostic assays play a crucial role in developing countries, where there are limit...

journal_title：Scientific reports

authors： Shafiee H,Asghar W,Inci F,Yuksekkaya M,Jahangir M,Zhang MH,Durmus NG,Gurkan UA,Kuritzkes DR,Demirci U

更新日期：2015-03-06 00:00:00

abstract：:Social context influences social decisions and outcome processing, partially depending on inter-individual differences. The present study investigated social context-dependent modulation of behavior and feedback processing in the ultimatum game (UG) in relation to inter-individual differences in social anxiety. Thirty...

journal_title：Scientific reports

authors： Peterburs J,Voegler R,Liepelt R,Schulze A,Wilhelm S,Ocklenburg S,Straube T

更新日期：2017-03-09 00:00:00

abstract：:Although the reversible wettability transition between hydrophobic and hydrophilic graphene under ultraviolet (UV) irradiation has been observed, the mechanism for this phenomenon remains unclear. In this work, experimental and theoretical investigations demonstrate that the H2O molecules are split into hydrogen and h...

journal_title：Scientific reports

authors： Xu Z,Ao Z,Chu D,Younis A,Li CM,Li S

更新日期：2014-09-23 00:00:00

abstract：:Although carbon nanotubes (CNTs) have shown great potential for enhancing the performance of polymer matrices, their reinforcement role still needs to be further improved. Here we implement a structural modification of multi-walled CNTs (MWCNTs) to fully utilize their fascinating mechanical and electrical properties v...

journal_title：Scientific reports

authors： Yang M,Weng L,Zhu H,Zhang F,Fan T,Zhang D

更新日期：2017-12-07 00:00:00

abstract：:The aim of this study was to investigate the characteristics of insulin producing cells (IPCs) differentiated from adipose-tissue derived stem cells (ADSCs) isolated from human subcutaneous and visceral adipose tissues and identify ADSCs suitable for differentiation into efficient and functional IPCs. Subcutaneous and...

journal_title：Scientific reports

authors： Wada Y,Ikemoto T,Morine Y,Imura S,Saito Y,Yamada S,Shimada M

更新日期：2019-09-13 00:00:00

abstract：:Acid-base homeostasis is critical for normal growth, development, and hearing function. The sodium-hydrogen exchanger 6 (NHE6), a protein mainly expressed in early and recycling endosomes, plays an important role in regulating organellar pH. Mutations in NHE6 cause complex, slowly progressive neurodegeneration. Little...

journal_title：Scientific reports

authors： Kucharava K,Brand Y,Albano G,Sekulic-Jablanovic M,Glutz A,Xian X,Herz J,Bodmer D,Fuster DG,Petkovic V

更新日期：2020-02-27 00:00:00

abstract：:Melimine and Mel4 are chimeric cationic peptides with broad-spectrum antimicrobial activity. They have been shown to be highly biocompatible in animal models and human clinical trials. The current study examined the mechanism of action of these two antimicrobial peptides against P. aeruginosa. The effect of the peptid...

journal_title：Scientific reports

authors： Yasir M,Dutta D,Willcox MDP

更新日期：2019-05-08 00:00:00

abstract：:Previous studies reported that boreal winter precipitation in southeastern China (SEC) tends to increase during El Niño. In this study, however, we find that most weak El Niño events are accompanied by below-normal precipitation in SEC, although strong El Niño events are accompanied by above-normal precipitation in SE...

journal_title：Scientific reports

authors： Ke Z,Jiang X,Wang Z

更新日期：2019-11-22 00:00:00

abstract：:Some key behavioural traits of Autism Spectrum Disorders (ASD) have been hypothesized to be due to impairments in the early activation of subcortical orienting mechanisms, which in typical development bias newborns to orient to relevant social visual stimuli. A challenge to testing this hypothesis is that autism is us...

journal_title：Scientific reports

authors： Di Giorgio E,Frasnelli E,Rosa Salva O,Scattoni ML,Puopolo M,Tosoni D,NIDA-Network.,Simion F,Vallortigara G

更新日期：2016-05-20 00:00:00

abstract：:Metabolic images from Positron Emission Tomography (PET) are used routinely for diagnosis, follow-up or treatment planning purposes of cancer patients. In this study we aimed at determining if radiomic features extracted from 18F-Fluoro Deoxy Glucose (FDG) PET images could mirror tumor transcriptomics. In this study w...

journal_title：Scientific reports

authors： Tixier F,Cheze-le-Rest C,Schick U,Simon B,Dufour X,Key S,Pradier O,Aubry M,Hatt M,Corcos L,Visvikis D

更新日期：2020-03-27 00:00:00

abstract：:Multiplexed gene expression optimization via modulation of gene translation efficiency through ribosome binding site (RBS) engineering is a valuable approach for optimizing artificial properties in bacteria, ranging from genetic circuits to production pathways. Established algorithms design smart RBS-libraries based o...

journal_title：Scientific reports

authors： Oesterle S,Gerngross D,Schmitt S,Roberts TM,Panke S

更新日期：2017-09-26 00:00:00

abstract：:Stress and recovery from stress significantly affect interactions between the central nervous system, endocrine pathways, and the immune system. However, the influence of acute stress on circulating immune-endocrine mediators in humans is not well known. Using a double-blind, randomized study design, we administered a...

journal_title：Scientific reports

authors： Koelsch S,Boehlig A,Hohenadel M,Nitsche I,Bauer K,Sack U

更新日期：2016-03-29 00:00:00

abstract：:Statins are well known to have muscle toxicity problem. Herba Cistanches (HC) is a Chinese herb traditionally used for pain in the loins and knees. Our previous in vitro study suggested that it could protect against statin-induced muscle toxicity. However, its in vivo protective effect has never been investigated. The...

journal_title：Scientific reports

authors： Wat E,Ng CF,Koon CM,Zhang C,Gao S,Tomlinson B,Lau CBS

更新日期：2017-08-24 00:00:00

abstract：:In general, the poultry industry uses 0.5-1 ppm chlorine solution in the meat sanitization process. However, chlorine can react with organic material and produce halogenated organic compounds, notably chloroform, which causes bladder and rectal cancer in humans. For this reason, many industries try to avoid chlorine. ...

journal_title：Scientific reports

authors： Royintarat T,Choi EH,Boonyawan D,Seesuriyachan P,Wattanutchariya W

更新日期：2020-01-31 00:00:00

abstract：:Robust biomarker quantification is essential for the accurate diagnosis of diseases and is of great value in cancer management. In this paper, an innovative diagnostic platform is presented which provides automated molecularly imprinted solid-phase extraction (MISPE) followed by liquid chromatography-mass spectrometry...

journal_title：Scientific reports

authors： Rossetti C,Świtnicka-Plak MA,Grønhaug Halvorsen T,Cormack PA,Sellergren B,Reubsaet L

更新日期：2017-03-17 00:00:00

abstract：:In eukaryotes, RNA silencing, mediated by small interfering RNAs, is an evolutionarily widespread and versatile silencing mechanism that plays an important role in various biological processes. Increasing evidences suggest that various components of RNA silencing pathway are involved in plant defense machinery against...

journal_title：Scientific reports

authors： Uddin MN,Akhter S,Chakraborty R,Baek JH,Cha JY,Park SJ,Kang H,Kim WY,Lee SY,Mackey D,Kim MG

更新日期：2017-08-29 00:00:00

abstract：:Most tropical evergreen rain forests are characterised by varying degrees of precipitation seasonality that influence plant phenology and litterfall dynamics. Soil microbes are sensitive to soil water:air ratio and to nutrient availability. We studied if within-year seasonality in precipitation and litterfall-derived ...

journal_title：Scientific reports

authors： Buscardo E,Geml J,Schmidt SK,Freitas H,da Cunha HB,Nagy L

更新日期：2018-03-12 00:00:00

abstract：:The increasing availability of electronic health care records has provided remarkable progress in the field of population health. In particular the identification of disease risk factors has flourished under the surge of available data. Researchers can now access patient data across a broad range of demographics and g...

journal_title：Scientific reports

authors： Feldman K,Stiglic G,Dasgupta D,Kricheff M,Obradovic Z,Chawla NV

更新日期：2016-07-27 00:00:00