SDE5, a putative RNA export protein, participates in plant innate immunity through a flagellin-dependent signaling pathway in Arabidopsis.

abstract：:We aimed to investigate the potential of preoperative mammographic breast density (MBD) as a prognostic factor in breast cancer. Data of 969 patients with primary breast cancer were analyzed. We defined low MBD as fatty or fibroglandular breast, and high MBD as heterogeneously dense or extremely dense breast, respecti...

journal_title：Scientific reports

authors： Hwang KT,Chu AJ,Kim J,Lee JY,Chang JH,Oh S,Kim YA,Jung J,Oh B

更新日期：2018-10-30 00:00:00

abstract：:Plasma dipeptidyl-peptidase-4 activity (DPP4a) is inversely associated with left ventricular function in patients with heart failure (HF) or diabetes. However, the association between DPP4a and left ventricular function in ST-segment elevation myocardial infarction (STEMI) patients has not been reported. We studied th...

journal_title：Scientific reports

authors： Li JW,Chen YD,Liu YQ,Wang JD,Chen WR,Zhang YQ,Ma Q

更新日期：2017-07-21 00:00:00

abstract：:Organic carbon (OC) stability in tropical soils is strongly interlinked with multivalent cation interaction and mineral association. Low molecular weight organic acids (LMWOAs) represent the readily biodegradable OC. Therefore, investigating retention mechanisms of LMWOAs in mineral-cation-LMWOAs systems is critical t...

journal_title：Scientific reports

authors： Yang J,Wang J,Pan W,Regier T,Hu Y,Rumpel C,Bolan N,Sparks D

更新日期：2016-05-23 00:00:00

abstract：:When and where animals breed can shape the genetic structure and diversity of animal populations. The importance of drivers of genetic diversity is amplified in island populations that tend to have more delineated gene pools compared to continental populations. Studies of relatedness as a function of the spatial distr...

journal_title：Scientific reports

authors： Garrett LJH,Myatt JP,Sadler JP,Dawson DA,Hipperson H,Colbourne JK,Dickey RC,Weber SB,Reynolds SJ

更新日期：2020-11-26 00:00:00

abstract：:Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors with low survival rates and the leading cause of death in neurofibromatosis type 1 (NF1) patients under 40 years old. Surgical resection is the standard of care for MPNSTs, but is often incomplete and can generate loss of function, necessitating t...

journal_title：Scientific reports

authors： Sweeney EE,Burga RA,Li C,Zhu Y,Fernandes R

更新日期：2016-11-11 00:00:00

abstract：:Nowadays efficient down conversion for white light emission is mainly based on rare-earth doped phosphors or cadmium-containing quantum dots. Although they exhibit high luminescence efficiency, the rare-earth mining and cadmium pollution have so far led to extremely high environmental cost, which conflicts the origina...

journal_title：Scientific reports

authors： Shen PC,Lin MS,Lin CF

更新日期：2014-06-16 00:00:00

abstract：:Extracellular vesicles derived from mesenchymal stem cells (MSCs) represent a novel approach for regenerative and immunosuppressive therapy. Recently, cytochalasin B-induced microvesicles (CIMVs) were shown to be effective drug delivery mediators. However, little is known about their immunological properties. We propo...

journal_title：Scientific reports

authors： Gomzikova MO,Aimaletdinov AM,Bondar OV,Starostina IG,Gorshkova NV,Neustroeva OA,Kletukhina SK,Kurbangaleeva SV,Vorobev VV,Garanina EE,Persson JL,Jeyapalan J,Mongan NP,Khaiboullina SF,Rizvanov AA

更新日期：2020-07-01 00:00:00

abstract：:Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. However, the TM4SF1-associated signaling network in metastasis remains unknown. In the present study, we found that TM4SF1 affected the format...

journal_title：Scientific reports

authors： Yang JC,Zhang Y,He SJ,Li MM,Cai XL,Wang H,Xu LM,Cao J

更新日期：2017-04-03 00:00:00

abstract：:Endoconidiophora resinifera (=Ceratocystis resinifera) is a blue-stain fungus that occurs on conifers. The data showed that the Endoconidiophora resinifera mitochondrial genome is one of the largest mitochondrial genomes (>220 kb) so far reported among members of the Ascomycota. An exceptional large number of introns ...

journal_title：Scientific reports

authors： Zubaer A,Wai A,Hausner G

更新日期：2018-12-04 00:00:00

abstract：:This study is to investigate the frequencies of T-helper (Th)22, Th17 and Th1 cells and the levels of related cytokines in subchondral bone marrow in patients with rheumatoid arthritis (RA). Bone marrow and peripheral blood samples were collected from RA, osteoarthritis (OA) patients and healthy controls. The frequenc...

journal_title：Scientific reports

authors： Li S,Yin H,Zhang K,Wang T,Yang Y,Liu X,Chang X,Zhang M,Yan X,Ren Y,Pan W,Zhang L

更新日期：2017-07-06 00:00:00

abstract：:We report here the design and multiple functions of a new hierarchical nanotheronostic platform consisting of an upconversion nanoparticle (UCNP) core: shell with an additional mesoporous silica (mSiO2) matrix load shell containing sealed, high concentration of ICG molecules. We demonstrate that this UCNP@mSiO2-ICG na...

journal_title：Scientific reports

authors： Lv R,Wang D,Xiao L,Chen G,Xia J,Prasad PN

更新日期：2017-11-16 00:00:00

abstract：:Polymer-supported nanozero-valent iron composites (D001-nZVI) were fabricated for the removal of lead ions from aqueous solutions by embedding nZVI into the porous polystyrene anion exchanger D001. Humic acid (HA) was selected as a model species because of its ubiquitous existence to gain insight into the influencing ...

journal_title：Scientific reports

authors： Wang L,Wei S,Jiang Z

更新日期：2020-11-12 00:00:00

abstract：:The objective of our study is to highlight the therapeutic effect and mechanism of action by which purified Flaxseed hydrolysate (PFH) which is a lignan rich fraction exerts its anticancer activity on a human breast cancer cell line (T47D) and in mice bearing tumor. HPLC analysis of PFH of six flaxseed cultivars had s...

journal_title：Scientific reports

authors： Ezzat SM,Shouman SA,Elkhoely A,Attia YM,Elsesy MS,El Senousy AS,Choucry MA,El Gayed SH,El Sayed AA,Sattar EA,El Tanbouly N

更新日期：2018-01-11 00:00:00

abstract：:Internet gaming disorder (IGD) has been conceptualized as a behavioral addiction and shares clinical, neuropsychological, and personality characteristics with alcohol use disorder (AUD), but IGD dose not entail brain exposure to toxic agents, which renders it different from AUD. To achieve a clear understanding of the...

journal_title：Scientific reports

authors： Yoon EJ,Choi JS,Kim H,Sohn BK,Jung HY,Lee JY,Kim DJ,Park SW,Kim YK

更新日期：2017-07-18 00:00:00

abstract：:Fish reproductive success is linked to the ability of couples to mate and produce clutches that successfully hatch. Environmental stressors like high temperature and low pH can jeopardize this energetically costly process. In this study, exposure to high temperature and low pH was tested on a marine temperate species,...

journal_title：Scientific reports

authors： Lopes AF,Faria AM,Dupont S

更新日期：2020-11-30 00:00:00

abstract：:Perturbations in lipid metabolic pathways to meet the bioenergetic and biosynthetic requirements is a principal characteristic of cancer cells. Sphingolipids (SPLs) are the largest class of bioactive lipids associated to various aspects of tumorigenesis and have been extensively studied in cancer cell lines and experi...

journal_title：Scientific reports

authors： Bhadwal P,Dahiya D,Shinde D,Vaiphei K,Math RGH,Randhawa V,Agnihotri N

更新日期：2020-03-13 00:00:00

abstract：:A unique combination of useful properties in boron-carbide, such as extreme hardness, excellent fracture toughness, a low density, a high melting point, thermoelectricity, semi-conducting behavior, catalytic activity and a remarkably good chemical stability, makes it an ideal material for a wide range of technological...

journal_title：Scientific reports

authors： Mondal S,Bykova E,Dey S,Ali SI,Dubrovinskaia N,Dubrovinsky L,Parakhonskiy G,van Smaalen S

更新日期：2016-01-18 00:00:00

abstract：:Filamentous fungi grow exclusively at their tips, where many growth-related fungal processes, such as enzyme secretion and invasion into host cells, take place. Hyphal tips are also a site of active metabolism. Understanding metabolic dynamics within the tip region is therefore important for biotechnology and medicine...

journal_title：Scientific reports

authors： Yasuda M,Takeshita N,Shigeto S

更新日期：2021-01-14 00:00:00

abstract：:Colorectal cancer is one of the main causes of cancer death worldwide, and novel biomarkers are urgently needed for its early diagnosis and treatment. The utilization of metabolomics to identify and quantify metabolites in body fluids may allow the detection of changes in their concentrations that could serve as diagn...

journal_title：Scientific reports

authors： Martín-Blázquez A,Díaz C,González-Flores E,Franco-Rivas D,Jiménez-Luna C,Melguizo C,Prados J,Genilloud O,Vicente F,Caba O,Pérez Del Palacio J

更新日期：2019-12-27 00:00:00

abstract：:Bioartificial livers (BAL) may offer acute liver failure (ALF) patients an opportunity for cure without liver transplantation. We evaluated the efficacy of a spheroid-based BAL system, containing aggregates of porcine hepatocytes, in a porcine model of ALF. ALF pigs were divided into three groups. The control group co...

journal_title：Scientific reports

authors： Lee JH,Lee DH,Lee S,Kwon CHD,Ryu JN,Noh JK,Jang IK,Park HJ,Yoon HH,Park JK,Kim YJ,Kim SK,Lee SK

更新日期：2017-06-19 00:00:00

abstract：:Heme-copper oxygen reductases are terminal respiratory enzymes, catalyzing the reduction of dioxygen to water and the translocation of protons across the membrane. Oxygen consumption is inhibited by various substances. Here we tested the relatively unknown inhibition of cytochrome c oxidase (CcO) with isocyanate. In c...

journal_title：Scientific reports

authors： Kruse F,Nguyen AD,Dragelj J,Schlesinger R,Heberle J,Mroginski MA,Weidinger IM

更新日期：2020-03-02 00:00:00

abstract：:The identification of the earliest dogs is challenging because of the absence and/or mosaic pattern of morphological diagnostic features in the initial phases of the domestication process. Furthermore, the natural occurrence of some of these characters in Late Pleistocene wolf populations and the time it took from the...

journal_title：Scientific reports

authors： Boschin F,Bernardini F,Pilli E,Vai S,Zanolli C,Tagliacozzo A,Fico R,Fedi M,Corny J,Dreossi D,Lari M,Modi A,Vergata C,Tuniz C,Moroni A,Boscato P,Caramelli D,Ronchitelli A

更新日期：2020-08-07 00:00:00

abstract：:Ring-opening graft polymerization (ROGP) of L-Lactide (L-LA) is a practical method of altering the physical and chemical properties of lignocellulose. Previous studies have mainly investigated cellulose and tin-based catalysts, particularly of tin(II) 2-ethylhexanoate (Sn(oct)2), at high temperatures and reported low ...

journal_title：Scientific reports

authors： Zhang X,Wang H,Liu C,Zhang A,Ren J

更新日期：2017-04-03 00:00:00

abstract：:Centrioles are essential for forming cilia, flagella and centrosomes. Successful centriole assembly requires proteins of the SAS-6 family, which can form oligomeric ring structures with ninefold symmetry in vitro. While important progress has been made in understanding SAS-6 protein biophysics, the mechanisms enabling...

journal_title：Scientific reports

authors： Klein HC,Guichard P,Hamel V,Gönczy P,Schwarz US

更新日期：2016-06-08 00:00:00

abstract：:In this study, we developed a novel poly (lactic-co-glycolic acid)-dextran (PLD)-based nanodelivery system to enhance the anticancer potential of cisplatin (CDDP) in osteosarcoma cells. A nanosized CDDP-loaded PLGA-DX nanoparticle (PLD/CDDP) controlled the release rate of CDDP up to 48 h. In vitro cytotoxicity assay s...

journal_title：Scientific reports

authors： Liu P,Sun L,Zhou DS,Zhang P,Wang YH,Li D,Li QH,Feng RJ

更新日期：2015-12-01 00:00:00

abstract：:Published data have shown inconsistent results about the pharmacogenetics of XRCC1 gene on clinical outcomes of advanced lung cancer patients treated with platinum-based chemotherapy. This meta-analysis aimed to summarize published findings and provide more reliable association. A total of 53 eligible studies includin...

journal_title：Scientific reports

authors： Yuan Z,Li J,Hu R,Jiao Y,Han Y,Weng Q

更新日期：2015-11-20 00:00:00

abstract：:NLRP3 inflammasomes recognize non-microbial danger signals and induce release of proinflammatory cytokine interleukin (IL)-1β, leading to sterile inflammation in cardiovascular disease. Because sterile inflammation is involved in doxorubicin (Dox)-induced cardiotoxicity, we investigated the role of NLRP3 inflammasomes...

journal_title：Scientific reports

authors： Kobayashi M,Usui F,Karasawa T,Kawashima A,Kimura H,Mizushina Y,Shirasuna K,Mizukami H,Kasahara T,Hasebe N,Takahashi M

更新日期：2016-05-26 00:00:00

abstract：:Inbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males increases fetal resorption to 20-35% with an associated decline in placentation and maintenance of maternal Th1 immunity. More recently other complications of p...

journal_title：Scientific reports

authors： McKelvey KJ,Yenson VM,Ashton AW,Morris JM,McCracken SA

更新日期：2016-10-21 00:00:00

abstract：:We present new evidence that shows magma mingling can be a key process during highly explosive eruptions. Using fractal analysis of the size distribution of trachybasaltic fragments found on the inner walls of bubbles in trachytic pumices, we show that the more mafic component underwent fracturing during quenching aga...

journal_title：Scientific reports

authors： Paredes-Mariño J,Dobson KJ,Ortenzi G,Kueppers U,Morgavi D,Petrelli M,Hess KU,Laeger K,Porreca M,Pimentel A,Perugini D

更新日期：2017-12-04 00:00:00

abstract：:In eusocial Hymenoptera (ants, bees and wasps), queen and worker adult castes typically arise via environmental influences. A fundamental challenge is to understand how a single genome can thereby produce alternative phenotypes. A powerful approach is to compare the molecular basis of caste determination and different...

journal_title：Scientific reports

authors： Collins DH,Mohorianu I,Beckers M,Moulton V,Dalmay T,Bourke AF

更新日期：2017-03-31 00:00:00