The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues.

abstract：:Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contras...

journal_title：Scientific reports

authors： Ding Y,Zhang Y,Peng T,Lu Y,Jin D,Ren Q,Liu Y,Han J,Xi P

更新日期：2013-01-01 00:00:00

abstract：:The Longwangzhuang pluton is a typical example of Paleoproterozoic A-type granite intrusions at the southern margin of the North China Craton. This pluton is composed of arfvedsonite granite and minor aegirine-augite granites. Samples from both granite types display similar zircon U-Pb ages with 207U-206Pb ages of 161...

journal_title：Scientific reports

authors： Wang Y,Yang YZ,Siebel W,Zhang H,Zhang YS,Chen F

更新日期：2020-01-09 00:00:00

abstract：:Graphene oxide is being used in energy, optical, electronic and sensor devices due to its unique properties. However, unlike its counterpart - graphene - the thermal transport properties of graphene oxide remain unknown. In this work, we use large-scale molecular dynamics simulations with reactive potentials to system...

journal_title：Scientific reports

authors： Mu X,Wu X,Zhang T,Go DB,Luo T

更新日期：2014-01-28 00:00:00

abstract：:We describe the realization and characterization of a compact, autonomous fiber laser system that produces the optical frequencies required for laser cooling, trapping, manipulation, and detection of 87Rb atoms - a typical atomic species for emerging quantum technologies. This device, a customized laser system from th...

journal_title：Scientific reports

authors： Sabulsky DO,Junca J,Lefèvre G,Zou X,Bertoldi A,Battelier B,Prevedelli M,Stern G,Santoire J,Beaufils Q,Geiger R,Landragin A,Desruelle B,Bouyer P,Canuel B

更新日期：2020-02-24 00:00:00

abstract：:The secreted frizzled-related protein 5 gene (SFRP5) that antagonize the Wnt/β-catenin signaling is frequently inactivated by promoter methylation and oncogenic activation of the Wnt signaling pathway is common in many cancers. The curcumin-rich Curcuma longa has been reported to potent anti-cancer property involved i...

journal_title：Scientific reports

authors： Yen HY,Tsao CW,Lin YW,Kuo CC,Tsao CH,Liu CY

更新日期：2019-11-21 00:00:00

abstract：:We developed a virus-like particle (VLP)-based therapeutic vaccine against angiotensin II receptor type 1, ATR-AP205-001, which could significantly reduce the blood pressure and protect target organs of hypertensive animals. In this study, we focused on the immunological effect and safety of the VLP-based vaccine. By ...

journal_title：Scientific reports

authors： Hu X,Deng Y,Chen X,Zhou Y,Zhang H,Wu H,Yang S,Chen F,Zhou Z,Wang M,Qiu Z,Liao Y

更新日期：2017-10-03 00:00:00

abstract：:Learning rules by which cell shape impacts cell function would enable control of cell physiology and fate in medical applications, particularly, on the interface of cells and material of the implants. We defined the phenotypic response of human bone marrow-derived mesenchymal stem cells (hMSCs) to 2176 randomly genera...

journal_title：Scientific reports

authors： Vasilevich AS,Vermeulen S,Kamphuis M,Roumans N,Eroumé S,Hebels DGAJ,van de Peppel J,Reihs R,Beijer NRM,Carlier A,Carpenter AE,Singh S,de Boer J

更新日期：2020-11-04 00:00:00

abstract：:It is generally assumed that an investment into cognitive abilities and their associated cost is particularly beneficial for long-lived species, as a prolonged lifespan allows to recoup the initial investment. However, ephemeral organisms possess astonishing cognitive abilities too. Invertebrates, for example, are cap...

journal_title：Scientific reports

authors： Liedtke J,Fromhage L

更新日期：2019-10-23 00:00:00

abstract：:The Fukushima Daiichi nuclear power plant accident caused serious radiocesium (137Cs) contamination of the soil in multiple terrestrial ecosystems. Soil is a complex system where minerals, organic matter, and microorganisms interact with each other; therefore, an improved understanding of the interactions of 137Cs wit...

journal_title：Scientific reports

authors： Koarashi J,Nishimura S,Atarashi-Andoh M,Muto K,Matsunaga T

更新日期：2019-05-07 00:00:00

abstract：:Previous work has shown that human vision performs spatial integration of luminance contrast energy, where signals are squared and summed (with internal noise) over area at detection threshold. We tested that model here in an experiment using arrays of micro-pattern textures that varied in overall stimulus area and sp...

journal_title：Scientific reports

authors： Baker DH,Meese TS

更新日期：2016-07-27 00:00:00

abstract：:Olfactory dysfunction is a robust and early sign for Parkinson's disease (PD). Previous studies have revealed its association with dementia and related neural changes in PD. Yet, how olfactory dysfunction affects white matter (WM) microstructure in newly diagnosed and untreated PD remains unclear. Here we comprehensiv...

journal_title：Scientific reports

authors： Wen MC,Xu Z,Lu Z,Chan LL,Tan EK,Tan LCS

更新日期：2017-10-02 00:00:00

abstract：:The early life stages represent a crucial period that can strongly influence population dynamics. We studied the development of foraging behaviour in the red-footed booby, a tropical seabird with an extensive post-fledging care period (3 to 6 months). Adults and juveniles were observed from shore and tracked at sea us...

journal_title：Scientific reports

authors： Mendez L,Prudor A,Weimerskirch H

更新日期：2017-10-24 00:00:00

abstract：:Positron emission tomography (PET) imaging can assist in the early-phase diagnostic and therapeutic evaluation of tumors. Here, we report the radiosynthesis, small animal PET imaging, and biological evaluation of a L-type amino acid transporter 1 (LAT1)-specific PET probe, 18F-FIMP. This probe demonstrates increased t...

journal_title：Scientific reports

authors： Nozaki S,Nakatani Y,Mawatari A,Shibata N,Hume WE,Hayashinaka E,Wada Y,Doi H,Watanabe Y

更新日期：2019-10-31 00:00:00

abstract：:Transjugular intrahepatic portosystemic shunt (TIPS) is an effective therapy for reducing portal pressure. Hepatic myelopathy (HM), a rare complication of chronic liver diseases, remains obscure in terms of treatment and prognosis. We aimed to determine an optimal treat strategy for patients with HM after TIPS. Twenty...

journal_title：Scientific reports

authors： Zhao H,Yue Z,Wang L,Fan Z,He F,Dong X,Liu F

更新日期：2018-10-12 00:00:00

abstract：:The actinopterygians comprise nearly one-half of all extant vertebrate species and are very important for human well-being. However, the phylogenetic relationships among certain groups within the actinopterygians are still uncertain, and debates about these relationships have continued for a long time. Along with the ...

journal_title：Scientific reports

authors： Zou M,Guo B,Tao W,Arratia G,He S

更新日期：2012-01-01 00:00:00

abstract：:Secreted Protein Acidic and Rich in Cysteine (SPARC)-related modular calcium-binding protein-2 (SMOC2), a secreted matricellular protein, is reported to be involved in various processes related to cancer progression such as regulating the cell cycle, angiogenesis, and invasion. However, its expression and prognostic s...

journal_title：Scientific reports

authors： Kim HS,Choi JH,Lee JY,Kang J,Myung JK,Kim WH,Jang BG

更新日期：2020-03-17 00:00:00

abstract：:The introduced oriental shrimp Palaemon macrodactylus has recently become widespread in temperate estuaries worldwide. However, this recent worldwide spread outside of its native range arises after a previous introduction to the US Pacific coast, where it was restricted for more than 30 years. Using a phylogeographic ...

journal_title：Scientific reports

authors： Lejeusne C,Saunier A,Petit N,Béguer M,Otani M,Carlton JT,Rico C,Green AJ

更新日期：2014-07-24 00:00:00

abstract：:Moisture in materials can be a source of future outgassing and exacerbate unwanted changes in physical and chemical properties. Here, we investigate the effect of sample size and shape on the moisture transport phenomena through a combined experimental and modeling approach. Several different materials varying in size...

journal_title：Scientific reports

authors： Sharma HN,Sun Y,Glascoe EA

更新日期：2020-10-20 00:00:00

abstract：:Delivering gene constructs into the dorsal root ganglia (DRG) is a powerful but challenging therapeutic strategy for sensory disorders affecting the DRG and their peripheral processes. The current delivery methods of direct intra-DRG injection and intrathecal injection have several disadvantages, including potential i...

journal_title：Scientific reports

authors： Chang MF,Hsieh JH,Chiang H,Kan HW,Huang CM,Chellis L,Lin BS,Miaw SC,Pan CL,Chao CC,Hsieh ST

更新日期：2016-10-17 00:00:00

abstract：:In this contribution, a complete dissertation concerning the behavior of a Long Period Grating (LPG) inscribed in a B-Ge co-doped optical fiber by means of an excimer laser and exposed to proton irradiation during a recent extensive campaign performed at the European Organization for Nuclear Research (CERN) with a flu...

journal_title：Scientific reports

authors： Berruti GM,Vaiano P,Quero G,Pimentel Das Neves TF,Boniello A,Consales M,Petagna P,Cusano A

更新日期：2020-01-28 00:00:00

abstract：:The aim of this study was to identify genes for which the expression within carotid atherosclerosis was reproducibly associated with the symptoms of cerebral embolization. Two publically available microarray datasets E-MEXP-2257 and GSE21545 were analysed using GeneSpring 11.5. The two datasets utilized a total of 22 ...

journal_title：Scientific reports

authors： Biros E,Moran CS,Maguire J,Holliday E,Levi C,Golledge J

更新日期：2017-06-28 00:00:00

abstract：:Methanol (MOH) and monomethylamine (MMA) are two typical one-carbon (C1) compounds found in natural environments. They play an important role in marine and atmospheric chemistry, cloud formation, and global climate. The main biological sink of MOH and MMA is rapid consumption by marine microbes. Here, field-based time...

journal_title：Scientific reports

authors： Deng W,Peng L,Jiao N,Zhang Y

更新日期：2018-10-18 00:00:00

abstract：:We compare two approaches for deriving corrections to the "linear model" of cavity optomechanics, in order to describe effects that are beyond first order in the radiation pressure coupling. In the regime where the mechanical frequency is much lower than the cavity one, we compare: (I) a widely used phenomenological H...

journal_title：Scientific reports

authors： Sala K,Tufarelli T

更新日期：2018-06-14 00:00:00

abstract：:Tumor progression, limited efficacy of current standard treatments, and the rise in patient mortality are associated with gene expression caused by the synergistic action of intratumoral hypoxia and HIF-1α activation. For this reason, recent investigations have focused on HIF-targeting therapeutic agents, with encoura...

journal_title：Scientific reports

authors： Mangraviti A,Raghavan T,Volpin F,Skuli N,Gullotti D,Zhou J,Asnaghi L,Sankey E,Liu A,Wang Y,Lee DH,Gorelick N,Serra R,Peters M,Schriefer D,Delaspre F,Rodriguez FJ,Eberhart CG,Brem H,Olivi A,Tyler B

更新日期：2017-11-02 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and lethal malignancies. Long non-coding RNAs (lncRNAs) are a novel class of non-protein-coding transcripts that have been implicated in cancer biogenesis and prognosis. By repurposing microarray probes, we herein analysed the lncRNA expression...

journal_title：Scientific reports

authors： Fu XL,Liu DJ,Yan TT,Yang JY,Yang MW,Li J,Huo YM,Liu W,Zhang JF,Hong J,Hua R,Chen HY,Sun YW

更新日期：2016-09-15 00:00:00

abstract：:We recently showed that spinal cord injury (SCI) leads to a decrease in mRNA editing of serotonin receptor 2C (5-HT2CR) contributing to post-SCI spasticity. Here we study post-SCI mRNA editing and global gene expression using massively parallel sequencing. Evidence is presented that the decrease in 5-HT2CR editing is ...

journal_title：Scientific reports

authors： Di Narzo AF,Kozlenkov A,Ge Y,Zhang B,Sanelli L,May Z,Li Y,Fouad K,Cardozo C,Koonin EV,Bennett DJ,Dracheva S

更新日期：2015-07-30 00:00:00

abstract：:Ovule-derived haploid culture is an effective and important method for genetic study and plant breeding. Gerbera hybrida is a highly heterozygous species, and the lack of homozygous lines presents a challenge for molecular genetic research. Therefore, we performed haploid induction through unpollinated ovule culture a...

journal_title：Scientific reports

authors： Li F,Cheng Y,Zhao X,Yu R,Li H,Wang L,Li S,Shan Q

更新日期：2020-02-03 00:00:00

abstract：:An atmospheric component of the Philippine-Taiwan Oscillations (PTOa) is used to examine its potential connection with tropical cyclone (TC) frequency in the western North Pacific in the period of 1979-2014. During positive PTOa years, more TCs are observed in the tropical western Pacific south of 18 °N where cyclonic...

journal_title：Scientific reports

authors： Chang YK,Miyazawa Y,Kodaira T,Behera S

更新日期：2018-11-29 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is one of the most common inflammatory diseases resulting from habitual smoking. Impaired clearance of apoptotic cell by airway macrophages contributes to lung inflammation. Milk fat globule-EGF factor 8 (MFG-E8), as a link between apoptotic cells and phagocytes, facilitate...

journal_title：Scientific reports

authors： Wang Y,Luo G,Chen J,Jiang R,Zhu J,Hu N,Huang W,Cheng G,Jia M,Su B,Zhang N,Cui T

更新日期：2017-02-14 00:00:00

abstract：:Physical reservoir computing approaches have gained increased attention in recent years due to their potential for low-energy high-performance computing. Despite recent successes, there are bounds to what one can achieve simply by making physical reservoirs larger. Therefore, we argue that a switch from single-reservo...

journal_title：Scientific reports

authors： Freiberger M,Bienstman P,Dambre J

更新日期：2020-09-02 00:00:00