Magnetic-assisted triboelectric nanogenerators as self-powered visualized omnidirectional tilt sensing system.

abstract：:MicroRNAs (miRNAs) are important effectors in mediating host-pathogen interaction. In this report, coelomocytes miRNA libraries of three Japanese sea cucumbers Apostichopus japonicus were built by Illumina(®) Hiseq2000 from different time points after lipopolysaccharide challenge (at time 0 h, 6 h and 12 h). The clean...

journal_title：Scientific reports

authors： Zhong L,Zhang F,Zhai Y,Cao Y,Zhang S,Chang Y

更新日期：2015-12-04 00:00:00

abstract：:Rolling circle amplification (RCA) for generation of distinct fluorescent signals in situ relies upon the self-collapsing properties of single-stranded DNA in commonly used RCA-based methods. By introducing a cross-hybridizing DNA oligonucleotide during rolling circle amplification, we demonstrate that the fluorophore...

journal_title：Scientific reports

authors： Clausson CM,Arngården L,Ishaq O,Klaesson A,Kühnemund M,Grannas K,Koos B,Qian X,Ranefall P,Krzywkowski T,Brismar H,Nilsson M,Wählby C,Söderberg O

更新日期：2015-07-23 00:00:00

abstract：:Acrolein, a highly toxic α, β-unsaturated aldehyde, has been a longstanding key biomarker associated with a range of disorders related to oxidative stresses. One of the most promising methods for detecting acrolein involves the use of antibodies that can recognize the acrolein-lysine conjugate, 3-formyl-3, 4-dehydropi...

journal_title：Scientific reports

authors： Takamatsu M,Fukase K,Oka R,Kitazume S,Taniguchi N,Tanaka K

更新日期：2016-10-26 00:00:00

abstract：:The study of cancer immunology has provided diagnostic and therapeutic instruments through serum autoantibody biomarkers and exogenous monoclonal antibodies. While some endogenous antibodies are found within or surrounding transformed tissue, the extent to which this exists has not been entirely characterized. We find...

journal_title：Scientific reports

authors： Rich BS,Honeyman JN,Darcy DG,Smith PT,Williams AR,Lim II,Johnson LK,Gönen M,Simon JS,LaQuaglia MP,Simon SM

更新日期：2014-05-30 00:00:00

abstract：:To date, the cell and molecular mechanisms regulating tendon healing are poorly understood. Here, we establish a novel model of tendon regeneration using neonatal mice and show that neonates heal via formation of a 'neo-tendon' that differentiates along the tendon specific lineage with functional restoration of gait a...

journal_title：Scientific reports

authors： Howell K,Chien C,Bell R,Laudier D,Tufa SF,Keene DR,Andarawis-Puri N,Huang AH

更新日期：2017-03-23 00:00:00

abstract：:A new concept for treatment of infections is induction of our own antimicrobial peptides and the presented novel class of inducer, aroylated phenylenediamines (APDs), gives up to 20 to 30-fold induction of the human antimicrobial peptide LL-37, in vitro. In addition, oral administration of an APD in a rabbit model of ...

journal_title：Scientific reports

authors： Ottosson H,Nylén F,Sarker P,Miraglia E,Bergman P,Gudmundsson GH,Raqib R,Agerberth B,Strömberg R

更新日期：2016-11-09 00:00:00

abstract：:We investigated the association of redox regulator Nuclear factor erythroid 2-related factor 2 (Nrf2) and inflammatory cytokines as well as clinical remission in patients with recent onset type 2 diabetes (DM). Blood was collected from 180 DM patients (105 males/75 females) and 150 control subjects (86 males/64 female...

journal_title：Scientific reports

authors： Sireesh D,Dhamodharan U,Ezhilarasi K,Vijay V,Ramkumar KM

更新日期：2018-03-23 00:00:00

abstract：:Craniofacial muscles drive critical functions in the head, including speech, feeding and expression. Compared with their counterparts in trunk and limbs, craniofacial muscles are of distinct embryonic origins, which might consequently lead to different growth patterns and regenerative potential. In this study, rat lev...

journal_title：Scientific reports

authors： Cheng X,Huang H,Luo X,Shi B,Li J

更新日期：2018-07-13 00:00:00

abstract：:With the development and application of nanotechnology, large amounts of nanoparticles will be potentially released to the environment and possibly cause many severe health problems. Although the toxicity of nanoparticles has been investigated, prevention and treatment of damages caused by nanoparticles have been rare...

journal_title：Scientific reports

authors： Qi W,Tian L,An W,Wu Q,Liu J,Jiang C,Yang J,Tang B,Zhang Y,Xie K,Wang X,Li Z,Wu W

更新日期：2017-06-06 00:00:00

abstract：:Large-scale molecular epidemiologic studies of Plasmodium falciparum parasites have provided insights into parasite biology and transmission, can identify the spread of drug resistance, and are useful in assessing vaccine targets. The polyclonal nature infections in high transmission settings is problematic for tradit...

journal_title：Scientific reports

authors： Levitt B,Obala A,Langdon S,Corcoran D,O'Meara WP,Taylor SM

更新日期：2017-01-24 00:00:00

abstract：:Differential scanning fluorimetry is a popular method to estimate the stability of a protein in distinct buffer conditions by determining its 'melting point'. The method requires a temperature controlled fluorescence spectrometer or a RT-PCR machine. Here, we introduce a low-budget version of a microcontroller based h...

journal_title：Scientific reports

authors： Hoeser J,Gnandt E,Friedrich T

更新日期：2018-01-23 00:00:00

abstract：:Both between- and within-individual variation in behaviour can be important in determining mating opportunities and reproductive outcomes. Such behavioural variability can be induced by environmental conditions, especially if individuals vary in their tolerance levels or resource allocation patterns. We tested the eff...

journal_title：Scientific reports

authors： Lehtonen TK,Svensson PA,Wong BBM

更新日期：2018-06-19 00:00:00

abstract：:The overpopulation of abandoned and stray companion animals has become a global crisis. The main purpose of this study was to develop a novel nanomedicine-based antifertility compound for non-surgical castration of male animals. Mangosteen (Garcinia mangostana L) pericarp extract has been shown to exhibit anti-fertili...

journal_title：Scientific reports

authors： Yostawonkul J,Surassmo S,Namdee K,Khongkow M,Boonthum C,Pagseesing S,Saengkrit N,Ruktanonchai UR,Chatdarong K,Ponglowhapan S,Yata T

更新日期：2017-11-24 00:00:00

abstract：:Prostate cancer (PCa) is the most common solid neoplasm diagnosed in developed countries. Nerve-sparing radical prostatectomy (NS-RP) has been widely accepted as the best choice treatment for localised PCa. However, erectile dysfunction (ED) and urinary incontinence are commonly observed after NS-RP. Using meta-analys...

journal_title：Scientific reports

authors： Li J,Shi Q,Pu C,Tang Y,Bai Y,Yuan H,Li X,Dong Q,Wei Q,Yuan J,Han P

更新日期：2014-07-23 00:00:00

abstract：:Light chain (AL) amyloidosis, caused by deposition of amyloidogenic immunoglobulin light chains (LCs), is the most common systemic form in industrialized countries. Still open questions, and premises for developing targeted therapies, concern the mechanisms of amyloid formation in vivo and the bases of organ targeting...

journal_title：Scientific reports

authors： Ami D,Lavatelli F,Rognoni P,Palladini G,Raimondi S,Giorgetti S,Monti L,Doglia SM,Natalello A,Merlini G

更新日期：2016-07-04 00:00:00

abstract：:Invasive alien species represent one of the major factors of global loss of biodiversity and disruption of natural ecosystems. The small Indian mongoose, Urva auropunctata, is considered one of the wild carnivore species with the greatest negative impact on global biodiversity. Understanding of the factors underpinnin...

journal_title：Scientific reports

authors： Louppe V,Leroy B,Herrel A,Veron G

更新日期：2020-05-04 00:00:00

abstract：:Listeria monocytogenes is well known for having the ability to cross the placental barrier, leading to fetal infections and abortion. However, the mechanisms leading to infectious abortion are poorly understood. In this study, we demonstrate that interferon γ-induced GTPase (IGTP) contributes to the invasion of L. mon...

journal_title：Scientific reports

authors： Tachibana M,Hashino M,Watanabe K,Shimizu T,Watarai M

更新日期：2015-02-03 00:00:00

abstract：:During symbiosis, organisms use a range of metabolic and protein-based signals to communicate. Of these protein signals, one class is defined as 'effectors', i.e., small secreted proteins (SSPs) that cause phenotypical and physiological changes in another organism. To date, protein-based effectors have been described ...

journal_title：Scientific reports

authors： Plett JM,Yin H,Mewalal R,Hu R,Li T,Ranjan P,Jawdy S,De Paoli HC,Butler G,Burch-Smith TM,Guo HB,Ju Chen C,Kohler A,Anderson IC,Labbé JL,Martin F,Tuskan GA,Yang X

更新日期：2017-03-23 00:00:00

abstract：:Schizophrenia is a common neuropsychiatric disorder with a lifetime risk of 1%. Accumulation of common polygenic variations has been found to be an important risk factor. Recent studies showed a role for the enrichment of minor alleles (MAs) of SNPs in complex diseases such as Parkinson's disease. Here we similarly st...

journal_title：Scientific reports

authors： He P,Lei X,Yuan D,Zhu Z,Huang S

更新日期：2017-09-15 00:00:00

abstract：:The ability of human metaphase-II arrested eggs to activate following fertilisation declines with advancing maternal age. Egg activation is triggered by repetitive increases in intracellular Ca(2+) concentration ([Ca(2+)]i) in the ooplasm as a result of sperm-egg fusion. We therefore hypothesised that eggs from older ...

journal_title：Scientific reports

authors： Haverfield J,Nakagawa S,Love D,Tsichlaki E,Nomikos M,Lai FA,Swann K,FitzHarris G

更新日期：2016-01-20 00:00:00

abstract：:Semen fertilizing potential is dependent upon the morphological, functional and molecular attributes of sperm. Sperm microRNAs (miRNAs) were recently shown to hold promise regarding their association with different fertility phenotypes. However, their role in fertility regulation remains to be determined. We postulate...

journal_title：Scientific reports

authors： Alves MBR,de Arruda RP,De Bem THC,Florez-Rodriguez SA,Sá Filho MF,Belleannée C,Meirelles FV,da Silveira JC,Perecin F,Celeghini ECC

更新日期：2019-07-17 00:00:00

abstract：:Murraya koenigii (MK) leaf being a rich source of bioactive secondary metabolites has received inordinate attention in drug development research. Formation of secondary plant metabolite(s) in medicinal plants depends on several factors and in this study the cause of variation in bioavailability and content of a vital ...

journal_title：Scientific reports

authors： Kandimalla R,Das M,Barge SR,Sarma PP,Koiri DJ,Devi A,Karki AK,Kumar A,Devi R,Pal BC,Talukdar NC,Samanta SK

更新日期：2020-11-18 00:00:00

abstract：:This paper reports a facile and green method for conversion of graphene oxide (GO) into graphene by low-temperature heating (80 °C) in the presence of a glass wafer. Compared to conventional GO chemical reduction methods, the presented approach is easy-scalable, operationally simple, and based on the use of a non-toxi...

journal_title：Scientific reports

authors： Rabchinskii MK,Dideikin AT,Kirilenko DA,Baidakova MV,Shnitov VV,Roth F,Konyakhin SV,Besedina NA,Pavlov SI,Kuricyn RA,Lebedeva NM,Brunkov PN,Vul' AY

更新日期：2018-09-20 00:00:00

abstract：:Macrophages play an important role in the inflammatory process that contributes to the development of abdominal aortic aneurysm (AAA). Studies of human and mouse AAA tissue reveal expanded populations of macrophages producing an abundance of pro-inflammatory cytokines, including TNF-α, IL-12p40 and high level of metal...

journal_title：Scientific reports

authors： Yan H,Hu Y,Akk A,Ye K,Bacon J,Pham CTN

更新日期：2019-07-18 00:00:00

abstract：:HSV-2 is one of the most common sexually transmitted pathogens worldwide and HSV-2 infection triggers cytokine and chemokine production. However, little is known about which HSV-2 genes engage in the regulation of NF-κB signaling and what mechanisms are involved. In a screen of the unique short (Us) regions of HSV-2, ...

journal_title：Scientific reports

authors： Lu X,Huang C,Zhang Y,Lin Y,Wang X,Li Q,Liu S,Tang J,Zhou L

更新日期：2017-08-21 00:00:00

abstract：:MicroRNAs can promote translation of specific mRNAs in quiescent (G0) mammalian cells and immature Xenopus laevis oocytes. We report that microRNA-mediated upregulation of target mRNAs in oocytes is dependent on nuclear entry of the microRNA; cytoplasmically-injected microRNA repress target mRNAs. Components of the ac...

journal_title：Scientific reports

authors： Truesdell SS,Mortensen RD,Seo M,Schroeder JC,Lee JH,LeTonqueze O,Vasudevan S

更新日期：2012-01-01 00:00:00

abstract：:The fluorination of p-type metal phthalocyanines produces n-type semiconductors, allowing the design of organic electronic circuits that contain inexpensive heterojunctions made from chemically and thermally stable p- and n-type organic semiconductors. For the evaluation of close to intrinsic transport properties, hig...

journal_title：Scientific reports

authors： Jiang H,Ye J,Hu P,Wei F,Du K,Wang N,Ba T,Feng S,Kloc C

更新日期：2014-12-19 00:00:00

abstract：:LMNA gene encodes lamins A and C, two major components of the nuclear lamina, a network of intermediate filaments underlying the inner nuclear membrane. Most of LMNA mutations are associated with cardiac and/or skeletal muscles defects. Muscle laminopathies include Emery-Dreifuss Muscular Dystrophy, Limb-Girdle Muscul...

journal_title：Scientific reports

authors： Janin A,Bauer D,Ratti F,Valla C,Bertrand A,Christin E,Chopin E,Streichenberger N,Bonne G,Gache V,Cohen T,Méjat A

更新日期：2018-04-04 00:00:00

abstract：:The AMP-activated kinase (AMPK) is a major energy sensor metabolic enzyme that is activated early during T cell immune responses but its role in the generation of effector T cells is still controversial. Using both in vitro and in vivo models of T cell proliferation, we show herein that AMPK is dispensable for early T...

journal_title：Scientific reports

authors： Lepez A,Pirnay T,Denanglaire S,Perez-Morga D,Vermeersch M,Leo O,Andris F

更新日期：2020-12-10 00:00:00

abstract：:Complex societies are shaped by social relationships between multiple individuals. The pressure to track these relationships has driven the evolution of social cognition in primates. Importantly, it can be adaptive to track not only personal relationships, but also those established between third-parties. Primates hav...

journal_title：Scientific reports

authors： Whitehouse J,Meunier H

更新日期：2020-06-17 00:00:00