Variation in biosynthesis of an effective anticancer secondary metabolite, mahanine in Murraya koenigii, conditional on soil physicochemistry and weather suitability.

abstract：:A two-dimensional (2D) material placed on an atomically flat substrate can lead to the formation of surface nanobubbles trapping different types of substances. In this paper graphene nanobubbles of the radius of 7-34 nm with argon atoms inside are studied using molecular dynamics (MD). All modeled graphene nanobubbles...

journal_title：Scientific reports

authors： Iakovlev E,Zhilyaev P,Akhatov I

更新日期：2017-12-20 00:00:00

abstract：:Thermodynamics is a branch of science blessed by an unparalleled combination of generality of scope and formal simplicity. Based on few natural assumptions together with the four laws, it sets the boundaries between possible and impossible in macroscopic aggregates of matter. This triggered groundbreaking achievements...

journal_title：Scientific reports

authors： Correa LA,Palao JP,Alonso D,Adesso G

更新日期：2014-02-04 00:00:00

abstract：:Individuals who are well integrated into society have greater access to resources and tend to live longer. Why some individuals are socially isolated and others are not is therefore puzzling from an evolutionary perspective. Answering this question requires establishing the mix of intrinsic and contextual factors that...

journal_title：Scientific reports

authors： Brent LJN,Ruiz-Lambides A,Platt ML

更新日期：2017-12-19 00:00:00

abstract：:After prolonged stay in an intensive care unit (ICU) patients often complain about cognitive impairments that affect health-related quality of life after discharge. The aim of this proof-of-concept study was to test the feasibility and effects of controlled visual and acoustic stimulation in a virtual reality (VR) set...

journal_title：Scientific reports

authors： Gerber SM,Jeitziner MM,Wyss P,Chesham A,Urwyler P,Müri RM,Jakob SM,Nef T

更新日期：2017-10-16 00:00:00

abstract：:Hollow silica spheres (HSS) with special interior spaces, high specific surface area and excellent adsorption and permeability performance were synthesized via micelle-template method using cetyl trimethyl ammonium bromide (CTAB) micelles as soft template and tetraethoxysilane (TEOS) as silica precursor. SEM, TEM, FT-...

journal_title：Scientific reports

authors： Bao Y,Wang T,Kang Q,Shi C,Ma J

更新日期：2017-04-21 00:00:00

abstract：:Muscle specific receptor tyrosine kinase (MuSK) is an essential postsynaptic transmembrane molecule that mediates clustering of acetylcholine receptors (AChR). MUSK exon 10 is alternatively skipped in human, but not in mouse. Skipping of this exon disrupts a cysteine-rich region (Fz-CRD), which is essential for Wnt-me...

journal_title：Scientific reports

authors： Nasrin F,Rahman MA,Masuda A,Ohe K,Takeda J,Ohno K

更新日期：2014-10-30 00:00:00

abstract：:Body contouring achieved via subcutaneous adipose tissue reduction has notably advanced over the past century, from suction assisted lipectomy to techniques with reduced degrees of invasiveness including laser, radiofrequency, high frequency focused ultrasound, cryolipolysis, and drug-based injection approaches. These...

journal_title：Scientific reports

authors： Pham TT,Stokolosa AM,Borden PA,Hansen KD,Hong EM,Krasieva TB,Sivoraphonh RH,Moy WJ,Heidari AE,Lee LH,Kim EH,Sun CH,Jia W,Mo J-,Kim S,Hill MG,Wong BJF

更新日期：2020-11-27 00:00:00

abstract：:Cucumber is an agriculturally and economically important vegetable crop worldwide. Fruit flesh thickness is an important trait for cucumber and also a central determinant of yield, yet little is known about the underlying mechanism of this trait. In this study, bulked segregant analysis (BSA) combined with specific le...

journal_title：Scientific reports

authors： Xu X,Lu L,Zhu B,Xu Q,Qi X,Chen X

更新日期：2015-10-28 00:00:00

abstract：:Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propo...

journal_title：Scientific reports

authors： Yoon C,Kang M,Hong JH,Yang TD,Xing J,Yoo H,Choi Y,Choi W

更新日期：2017-07-26 00:00:00

abstract：:Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional treatment strategies. I...

journal_title：Scientific reports

authors： Qayoom I,Verma R,Murugan PA,Raina DB,Teotia AK,Matheshwaran S,Nair NN,Tägil M,Lidgren L,Kumar A

更新日期：2020-08-24 00:00:00

abstract：:Neuropathic pain is a complex, chronic pain state that often accompanies tissue damage, inflammation or injury of the nervous system. However the underlying molecular mechanisms still remain unclear. Here, we showed that CXCL12 and CXCR4 were upregulated in the dorsal root ganglion (DRG) after chronic compression of D...

journal_title：Scientific reports

authors： Yu Y,Huang X,Di Y,Qu L,Fan N

更新日期：2017-07-18 00:00:00

abstract：:Antimicrobial peptides (AMPs) are peptide antibiotics with a broad spectrum of antimicrobial activities. Activity prediction of AMPs from their amino acid sequences is of great therapeutic importance but imposes challenges on prediction methods due to label interactions. In this paper we propose a novel multi-label le...

journal_title：Scientific reports

authors： Wang P,Ge R,Liu L,Xiao X,Li Y,Cai Y

更新日期：2017-05-19 00:00:00

abstract：:The weak correlation between pain and structural changes in knee osteoarthritis is widely reported. In a previous within-person, knee-matched case-control study among Caucasians, the severity of radiographic osteoarthritis (ROA) was strongly associated with both the presence of frequent knee pain and pain severity. We...

journal_title：Scientific reports

authors： Wang K,Kim HA,Felson DT,Xu L,Kim DH,Nevitt MC,Yoshimura N,Kawaguchi H,Lin J,Kang X,Zhang Y

更新日期：2018-01-22 00:00:00

abstract：:Targeted antineoplastic agents show great promise in the treatment of cancer, having the ability to impart cytotoxicity only to specific tumor types. However, these therapies do not experience uniform uptake throughout tumors, leading to sub-lethal cell killing that can impart treatment resistance, and cause problemat...

journal_title：Scientific reports

authors： Klein OJ,Yuan H,Nowell NH,Kaittanis C,Josephson L,Evans CL

更新日期：2017-10-17 00:00:00

abstract：:Free living nematodes (FLN) are microscopic worms found in all soils. While many FLN species are beneficial to crops, some species cause significant damage by feeding on roots and vectoring viruses. With the planned legislative removal of traditionally used chemical treatments, identification of new ways to manage FLN...

journal_title：Scientific reports

authors： O'Callaghan FE,Braga RA,Neilson R,MacFarlane SA,Dupuy LX

更新日期：2018-01-23 00:00:00

abstract：:Long-term supply of synthetic nitrogen (N) has the potential to affect the soil N processes. This study aimed to (i) establish N response curves to find the best balance between inputs and outputs of N over four ratoons; (ii) use 15N-labeled fertilizer to estimate the N recovery efficiency of fertilizer applied in the...

journal_title：Scientific reports

authors： Joris HAW,Vitti AC,Ferraz-Almeida R,Otto R,Cantarella H

更新日期：2020-11-02 00:00:00

abstract：:Cardiopulmonary resuscitation (CPR) training and its quality are critical in improving the survival rate of cardiac arrest. This randomized controlled study investigated the efficacy of a newly developed CPR training program for the public in a Taiwanese setting. A total of 832 adults were randomized to either a tradi...

journal_title：Scientific reports

authors： Chien CY,Fang SY,Tsai LH,Tsai SL,Chen CB,Seak CJ,Weng YM,Lin CC,Chien WC,Huang CH,Lin CY,Chaou CH,Liu PH,Tseng HJ,Chen JC,Peng SY,Cheng TH,Hsu KH,Ng CJ

更新日期：2020-06-22 00:00:00

abstract：:Somatostatin (SST)-positive interneurons in the anterior cingulate cortex (ACC) play important roles in neuronal diseases, memory and cognitive functions. However, their development in the ACC remains unclear. Using postnatal day 3 (P3) to P45 GIN mice, we found that most of the intrinsic membrane properties of SST in...

journal_title：Scientific reports

authors： Pan G,Yang JM,Hu XY,Li XM

更新日期：2016-06-20 00:00:00

abstract：:It has been an old unsolved puzzle to evolutionary theorists on which mechanisms would increase large-scale cooperation in human societies. Thus, how such mechanisms operate in a biological network is still not well understood. This study addresses these questions with empirical evidence from agent-based models design...

journal_title：Scientific reports

authors： Ezeigbo IC

更新日期：2017-12-11 00:00:00

abstract：:We have succeeded in developing hollow branching structure in vitro commonly observed in lung airway using primary lung airway epithelial cells. Cell concentration gradient is the key factor that determines production of the branching cellular structures, as optimization of this component removes the need for heteroty...

journal_title：Scientific reports

authors： Hagiwara M,Peng F,Ho CM

更新日期：2015-01-27 00:00:00

abstract：:In situ HfB2-SiC-VSi2 composite was fabricated by reactive pressureless sintering at the temperature of 2150 °C for 4 h under a vacuum atmosphere. In situ SiC and VSi2 reinforcements were formed using VC and Si powders as starting materials according to the following reaction: VC + 3Si = SiC + VSi2. Microstructural st...

journal_title：Scientific reports

authors： Ghadami S,Taheri-Nassaj E,Baharvandi HR,Ghadami F

更新日期：2020-10-06 00:00:00

abstract：:The causes underlying sex differences in lifespan are strongly debated. While females commonly outlive males in humans, this is generally less pronounced in societies before the demographic transition to low mortality and fertility rates. Life-history theory suggests that reduced reproduction should benefit female lif...

journal_title：Scientific reports

authors： Bolund E,Lummaa V,Smith KR,Hanson HA,Maklakov AA

更新日期：2016-04-18 00:00:00

abstract：:Cover crops (plants grown in an agricultural rotation between cash crops) can significantly improve soil quality via sequestering carbon, retaining nutrients, decreasing soil erosion, and maintaining belowground biodiversity. However, little is known about the effects of such plants upon soil structure. The aim of the...

journal_title：Scientific reports

authors： Bacq-Labreuil A,Crawford J,Mooney SJ,Neal AL,Ritz K

更新日期：2019-05-16 00:00:00

abstract：:The claim that organic agriculture produces higher levels of phytochemicals has been controversial for decades. Using strawberries as a model crop in field conditions, a preharvest leaf wounding stress was applied to study the production of phytochemicals in fruits. As a result phenolic compounds (PCs) and total solub...

journal_title：Scientific reports

authors： Ibanez F,Bang WY,Lombardini L,Cisneros-Zevallos L

更新日期：2019-12-17 00:00:00

abstract：:Anatomically realistic organ replicas or phantoms allow for accurate studies and reproducible research. To recreate a human kidney, mimicry of the elastic properties of the human kidney is crucial. However, none of the related work addressed the design and development of a kidney phantom using only silicone as materia...

journal_title：Scientific reports

authors： Hattab G,Ahlfeld T,Klimova A,Koepp A,Schuerer M,Speidel S

更新日期：2020-07-16 00:00:00

abstract：:We report the new insight into the dielectric barrier discharge (DBD) induced inactivation of Microcystis aeruginosa, the dominant algae which caused harmful cyanobacterial blooms in many developing countries. In contrast with the previous work, we employed flow cytometry to examine the algal cells, so that we could a...

journal_title：Scientific reports

authors： Li L,Zhang H,Huang Q

更新日期：2015-09-08 00:00:00

abstract：:A better understanding of functional changes in the intervertebral disc (IVD) and interaction with endplate is essential to elucidate the pathogenesis of IVD degeneration disease (IDDD). To date, the simultaneous depiction of 3D micro-architectural changes of endplate with aging and interaction with IVD remains a tech...

journal_title：Scientific reports

authors： Cao Y,Liao S,Zeng H,Ni S,Tintani F,Hao Y,Wang L,Wu T,Lu H,Duan C,Hu J

更新日期：2017-03-07 00:00:00

abstract：:The integral membrane-bound Nrf1 transcription factor fulfils important functions in maintaining cellular homeostasis and organ integrity, but how it is controlled vectorially is unknown. Herein, creative use of Gal4-based reporter assays with protease protection assays (GRAPPA), and double fluorescence protease prote...

journal_title：Scientific reports

authors： Zhang Y,Hayes JD

更新日期：2013-01-01 00:00:00

abstract：:Rapid histopathological evaluation of fresh, unfixed human tissue using optical sectioning microscopy would have applications to intraoperative surgical margin assessment. Microscopy with ultraviolet surface excitation (MUSE) is a low-cost optical sectioning technique using ultraviolet illumination which limits fluore...

journal_title：Scientific reports

authors： Yoshitake T,Giacomelli MG,Quintana LM,Vardeh H,Cahill LC,Faulkner-Jones BE,Connolly JL,Do D,Fujimoto JG

更新日期：2018-03-14 00:00:00

abstract：:Next generation sequencing (NGS) together with protein expression analysis is back bone of molecularly targeted therapy in precision medicine. Our retrospective study shows our experience with NGS of 324 genes in combination with protein expression in patients with advanced breast cancer (aBC). The primary purpose was...

journal_title：Scientific reports

authors： Hempel D,Ebner F,Garg A,Trepotec Z,Both A,Stein W,Gaumann A,Güttler L,Janni W,DeGregorio A,Hempel L,Milani V

更新日期：2020-06-26 00:00:00