Traditional versus blended CPR training program: A randomized controlled non-inferiority study.

Abstract:

:Cardiopulmonary resuscitation (CPR) training and its quality are critical in improving the survival rate of cardiac arrest. This randomized controlled study investigated the efficacy of a newly developed CPR training program for the public in a Taiwanese setting. A total of 832 adults were randomized to either a traditional or blended (18-minute e-learning plus 30-minute hands-on) compression-only CPR training program. The primary outcome was compression depth. Secondary outcomes included CPR knowledge test, practical test, quality of CPR performance, and skill retention. The mean compression depth was 5.21 cm and 5.24 cm in the blended and traditional groups, respectively. The mean difference in compression depth between groups was -0.04 (95% confidence interval -0.13 to infinity), demonstrating that the blended CPR training program was non-inferior to the traditional CPR training program in compression depth after initial training. Secondary outcome results were comparable between groups. Although the mean compression depth and rate were guideline-compliant, only half of the compressions were delivered with adequate depth and rate in both groups. CPR knowledge and skill retained similarly in both groups at 6 and 12 months after training. The blended CPR training program was non-inferior to the traditional CPR training program. However, there is still room for improvement in optimizing initial skill performance as well as skill retention. Clinical Trial Registration: NCT03586752; www.clinicaltrial.gov.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Chien CY,Fang SY,Tsai LH,Tsai SL,Chen CB,Seak CJ,Weng YM,Lin CC,Chien WC,Huang CH,Lin CY,Chaou CH,Liu PH,Tseng HJ,Chen JC,Peng SY,Cheng TH,Hsu KH,Ng CJ

doi

10.1038/s41598-020-67193-1

subject

Has Abstract

pub_date

2020-06-22 00:00:00

pages

10032

issue

1

issn

2045-2322

pii

10.1038/s41598-020-67193-1

journal_volume

10

pub_type

杂志文章,随机对照试验
  • A new strategy for integrating abundant oxygen functional groups into carbon felt electrode for vanadium redox flow batteries.

    abstract::The effects of surface treatment combining corona discharge and hydrogen peroxide (H2O2) on the electrochemical performance of carbon felt electrodes for vanadium redox flow batteries (VRFBs) have been thoroughly investigated. A high concentration of oxygen functional groups has been successfully introduced onto the s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06906

    authors: Kim KJ,Lee SW,Yim T,Kim JG,Choi JW,Kim JH,Park MS,Kim YJ

    更新日期:2014-11-04 00:00:00

  • Deep Neural Network Probabilistic Decoder for Stabilizer Codes.

    abstract::Neural networks can efficiently encode the probability distribution of errors in an error correcting code. Moreover, these distributions can be conditioned on the syndromes of the corresponding errors. This paves a path forward for a decoder that employs a neural network to calculate the conditional distribution, then...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11266-1

    authors: Krastanov S,Jiang L

    更新日期:2017-09-08 00:00:00

  • Penicilliumin B, a novel sesquiterpene methylcyclopentenedione from a deep sea-derived Penicillium strain with renoprotective activities.

    abstract::A novel sesquiterpene methylcyclopentenedione, penicilliumin B (1), was obtained from a deep sea-derived fungus Penicillium sp. F00120, together with three known sesquiterpene cyclohexenones (2-4). Penicilliumin B (1), presenting the first example with the sesquiterpene cyclopentenedione skeleton as natural products, ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11007-4

    authors: Lin X,Wu Q,Yu Y,Liang Z,Liu Y,Zhou L,Tang L,Zhou X

    更新日期:2017-09-07 00:00:00

  • Magnetic anisotropy, unusual hysteresis and putative "up-up-down" magnetic structure in EuTAl4Si2 (T = Rh and Ir).

    abstract::We present detailed investigations on single crystals of quaternary EuRhAl4Si2 and EuIrAl4Si2. The two compounds order antiferromagnetically at TN1 = 11.7 and 14.7 K, respectively, each undergoing two magnetic transitions. The magnetic properties in the ordered state present a large anisotropy despite Eu(2+)being an S...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep12021

    authors: Maurya A,Thamizhavel A,Dhar SK,Bonville P

    更新日期:2015-07-09 00:00:00

  • Ultrasound modulates ion channel currents.

    abstract::Transcranial focused ultrasound (US) has been demonstrated to stimulate neurons in animals and humans, but the mechanism of this effect is unknown. It has been hypothesized that US, a mechanical stimulus, may mediate cellular discharge by activating mechanosensitive ion channels embedded within cellular membranes. To ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24170

    authors: Kubanek J,Shi J,Marsh J,Chen D,Deng C,Cui J

    更新日期:2016-04-26 00:00:00

  • Random peptide mixtures entrapped within a copper-cuprite matrix: new antimicrobial agent against methicillin-resistant Staphylococcus aureus.

    abstract::The emergence of global antibiotic resistance necessitates the urgent need to develop new and effective antimicrobial agents. Combination of two antimicrobial agents can potentially improve antimicrobial potency and mitigate the development of resistance. Therefore, we have utilized metal molecular doping methodology ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47315-0

    authors: Bauer TS,Menagen B,Avnir D,Hayouka Z

    更新日期:2019-08-02 00:00:00

  • High rate of drug resistance among tuberculous meningitis cases in Shaanxi province, China.

    abstract::The clinical and mycobacterial features of tuberculous meningitis (TBM) cases in China are not well described; especially in western provinces with poor tuberculosis control. We prospectively enrolled patients in whom TBM was considered in Shaanxi Province, northwestern China, over a 2-year period (September 2010 to D...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25251

    authors: Wang T,Feng GD,Pang Y,Liu JY,Zhou Y,Yang YN,Dai W,Zhang L,Li Q,Gao Y,Chen P,Zhan LP,Marais BJ,Zhao YL,Zhao G

    更新日期:2016-05-04 00:00:00

  • Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration.

    abstract::Nuclear distribution element-like 1 (Ndel1) plays pivotal roles in diverse biological processes and is implicated in the pathogenesis of multiple neurodevelopmental disorders. Ndel1 function by regulating microtubules and intermediate filaments; however, its functional link with the actin cytoskeleton is largely unkno...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep31827

    authors: Hong JH,Kwak Y,Woo Y,Park C,Lee SA,Lee H,Park SJ,Suh Y,Suh BK,Goo BS,Mun DJ,Sanada K,Nguyen MD,Park SK

    更新日期:2016-08-22 00:00:00

  • Room temperature 90° phase-matching in zirconium and magnesium co-doped lithium niobate crystals.

    abstract::Laser has been widely used in many aspects, by now it is difficult to get each frequency that we want, and frequency conversion is an effective way to obtain different frequency laser through a nonlinear optical crystal. MgO-doped LiNbO3 (Mg:LN) crystal has usually been used for second harmonic generation (SHG) throug...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22205-z

    authors: Kong T,Liu H,Ge X,Qu D,Liu S,Chen S,Zhang L,Kong Y,Rupp R,Xu J

    更新日期:2018-03-01 00:00:00

  • Coherent Generation of Photo-Thermo-Acoustic Wave from Graphene Sheets.

    abstract::Many remarkable properties of graphene are derived from its large energy window for Dirac-like electronic states and have been explored for applications in electronics and photonics. In addition, strong electron-phonon interaction in graphene has led to efficient photo-thermo energy conversions, which has been harness...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep10582

    authors: Tian Y,Tian H,Wu YL,Zhu LL,Tao LQ,Zhang W,Shu Y,Xie D,Yang Y,Wei ZY,Lu XH,Ren TL,Shih CK,Zhao J

    更新日期:2015-06-08 00:00:00

  • Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete.

    abstract::Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body. Identification of bacterial factors promoting dissemination is crucial for syphilis vaccine development. An important step in dissemination is bact...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-01589-4

    authors: Kao WA,Pětrošová H,Ebady R,Lithgow KV,Rojas P,Zhang Y,Kim YE,Kim YR,Odisho T,Gupta N,Moter A,Cameron CE,Moriarty TJ

    更新日期:2017-05-08 00:00:00

  • QuanTI-FRET: a framework for quantitative FRET measurements in living cells.

    abstract::Förster Resonance Energy Transfer (FRET) allows for the visualization of nanometer-scale distances and distance changes. This sensitivity is regularly achieved in single-molecule experiments in vitro but is still challenging in biological materials. Despite many efforts, quantitative FRET in living samples is either r...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62924-w

    authors: Coullomb A,Bidan CM,Qian C,Wehnekamp F,Oddou C,Albigès-Rizo C,Lamb DC,Dupont A

    更新日期:2020-04-16 00:00:00

  • Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy.

    abstract::(R-)miniCHOP therapy, which delivers approximately half-doses of the (R-)CHOP regimen, has shown efficacy and safety in patients who are more than 80 years old. This study aimed to compare the area under the plasma concentration-time curves (AUCs) of vincristine (VCR), doxorubicin (DXR), and cyclophosphamide (CPA) bet...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-80706-2

    authors: Nakagawa J,Takahata T,Hyodo R,Chen Y,Hasui K,Sasaki K,Saito K,Ueno K,Hosoi K,Terui K,Sato A,Niioka T

    更新日期:2021-01-12 00:00:00

  • Theoretical and Experimental Study of Light-assisted Polymerization by Multimechanism Action.

    abstract::A novel bicomponent alkyd system was designed to decrease the usage of Cobalt-based drier due to its latent carcinogensis. The system was polymerized using a Cobalt-salt complex as an air-sensitive drier and an isopropylthioxanthone photoinitiator as a light-sensitive accelerator, as well as using irradiation in the f...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep38473

    authors: Zhou H,Song D,Zhong C,Ye G

    更新日期:2016-12-13 00:00:00

  • Neural predictors of cognitive improvement by multi-strategic memory training based on metamemory in older adults with subjective memory complaints.

    abstract::Previous studies have indicated that memory training may help older people improve cognition. However, evidence regarding who will benefit from such memory trainings has not been fully discovered yet. Understanding the clinical and neural inter-individual differences for predicting cognitive improvement is important f...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-19390-2

    authors: Park S,Ryu SH,Yoo Y,Yang JJ,Kwon H,Youn JH,Lee JM,Cho SJ,Lee JY

    更新日期:2018-01-18 00:00:00

  • Meta-genomic analysis of toilet waste from long distance flights; a step towards global surveillance of infectious diseases and antimicrobial resistance.

    abstract::Human populations worldwide are increasingly confronted with infectious diseases and antimicrobial resistance spreading faster and appearing more frequently. Knowledge regarding their occurrence and worldwide transmission is important to control outbreaks and prevent epidemics. Here, we performed shotgun sequencing of...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11444

    authors: Nordahl Petersen T,Rasmussen S,Hasman H,Carøe C,Bælum J,Schultz AC,Bergmark L,Svendsen CA,Lund O,Sicheritz-Pontén T,Aarestrup FM

    更新日期:2015-07-10 00:00:00

  • Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways.

    abstract::The Fanconi anemia pathway in coordination with homologous recombination is essential to repair interstrand crosslinks (ICLs) caused by cisplatin. TIP60 belongs to the MYST family of acetyltransferases and is involved in DNA repair and regulation of gene transcription. Although the physical interaction between the TIP...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04223-5

    authors: Su WP,Ho YC,Wu CK,Hsu SH,Shiu JL,Huang JC,Chang SB,Chiu WT,Hung JJ,Liu TL,Wu WS,Wu PY,Su WC,Chang JY,Liaw H

    更新日期:2017-06-20 00:00:00

  • Dose-dependent decrease in anti-oxidant capacity of whole blood after irradiation: A novel potential marker for biodosimetry.

    abstract::Many reports have demonstrated that radiation stimulates reactive oxygen species (ROS) production by mitochondria for a few hours to a few days after irradiation. However, these studies were performed using cell lines, and there is a lack of information about redox homeostasis in irradiated animals and humans. Blood r...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-25650-y

    authors: Sun L,Inaba Y,Sato K,Hirayama A,Tsuboi K,Okazaki R,Chida K,Moritake T

    更新日期:2018-05-09 00:00:00

  • Increased deficit of visual attention span with development in Chinese children with developmental dyslexia.

    abstract::It has been suggested that orthographic transparency and age changes may affect the relationship between visual attention span (VAS) deficit and reading difficulty. The present study explored the developmental trend of VAS in children with developmental dyslexia (DD) in Chinese, a logographic language with a deep orth...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-21578-5

    authors: Zhao J,Liu M,Liu H,Huang C

    更新日期:2018-02-16 00:00:00

  • Body mass index trajectories in the first two years and subsequent childhood cardio-metabolic outcomes: a prospective multi-ethnic Asian cohort study.

    abstract::We investigated body mass index (BMI) trajectories in the first 2 years of life in 1170 children from an Asian mother-offspring cohort in Singapore, and examined their predictors and associations with childhood cardio-metabolic risk measures at 5 years. Latent class growth mixture modelling analyses were performed to ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09046-y

    authors: Aris IM,Chen LW,Tint MT,Pang WW,Soh SE,Saw SM,Shek LP,Tan KH,Gluckman PD,Chong YS,Yap F,Godfrey KM,Kramer MS,Lee YS

    更新日期:2017-08-21 00:00:00

  • A 3D printing approach toward targeted intervention in telerehabilitation.

    abstract::Neuromuscular impairment requires adherence to a rehabilitation regimen for maximum recovery of motor function. Consumer-grade game controllers have emerged as a viable means to relay supervised physical therapy to patients' homes, thereby increasing their accessibility to healthcare. These controllers allow patients ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59927-y

    authors: Barak Ventura R,Rizzo A,Nov O,Porfiri M

    更新日期:2020-02-28 00:00:00

  • miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1.

    abstract::Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to oncogenesis and chem...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19995

    authors: Zhang Y,Zhou SY,Yan HZ,Xu DD,Chen HX,Wang XY,Wang X,Liu YT,Zhang L,Wang S,Zhou PJ,Fu WY,Ruan BB,Ma DL,Wang Y,Liu QY,Ren Z,Liu Z,Zhang R,Wang YF

    更新日期:2016-02-05 00:00:00

  • Modelling of substrate access and substrate binding to cephalosporin acylases.

    abstract::Semisynthetic cephalosporins are widely used antibiotics currently produced by different chemical steps under harsh conditions, which results in a considerable amount of toxic waste. Biocatalytic synthesis by the cephalosporin acylase from Pseudomonas sp. strain N176 is a promising alternative. Despite intensive engin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48849-z

    authors: Ferrario V,Fischer M,Zhu Y,Pleiss J

    更新日期:2019-08-27 00:00:00

  • Thermoelectric microscopy of magnetic skyrmions.

    abstract::The magnetic skyrmion is a nanoscale topological object characterized by the winding of magnetic moments, appearing in magnetic materials with broken inversion symmetry. Because of its low current threshold for driving the skyrmion motion, they have been intensely studied toward novel storage applications by using ele...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54833-4

    authors: Iguchi R,Kasai S,Koshikawa K,Chinone N,Suzuki S,Uchida KI

    更新日期:2019-12-05 00:00:00

  • Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine.

    abstract::Addiction to cocaine and other psychostimulants represents a major public health crisis. The development and persistence of addictive behaviors comes from a complex interaction of genes and environment - the precise mechanisms of which remain elusive. In recent years a surge of evidence has suggested that the gut micr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep35455

    authors: Kiraly DD,Walker DM,Calipari ES,Labonte B,Issler O,Pena CJ,Ribeiro EA,Russo SJ,Nestler EJ

    更新日期:2016-10-18 00:00:00

  • Gram Negative Bacterial Inflammation Ameliorated by the Plasma Protein Beta 2-Glycoprotein I.

    abstract::Lipopolysaccharide (LPS) is a major component of the outer wall of gram negative bacteria. In high doses LPS contributes to the inflammation in gram negative sepsis, and in low doses contributes to the low grade inflammation characteristic of the metabolic syndrome. We wanted to assess the role of beta2-glycoprotein I...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep33656

    authors: Zhou S,Chen G,Qi M,El-Assaad F,Wang Y,Dong S,Chen L,Yu D,Weaver JC,Beretov J,Krilis SA,Giannakopoulos B

    更新日期:2016-09-27 00:00:00

  • Endogenous emotion generation ability is associated with the capacity to form multimodal internal representations.

    abstract::Training the capacity to self-generate emotions can be a potent "vaccine" against negative stressors and be an effective intervention for affective psychopathology. However, due to a lack of knowledge about sources of individual differences in generation abilities, it is unclear how to optimally design such interventi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-20380-7

    authors: Engen H,Kanske P,Singer T

    更新日期:2018-01-31 00:00:00

  • A Mathematical Model for Enzyme Clustering in Glucose Metabolism.

    abstract::We have recently demonstrated that the rate-limiting enzymes in human glucose metabolism organize into cytoplasmic clusters to form a multienzyme complex, the glucosome, in at least three different sizes. Quantitative high-content imaging data support a hypothesis that the glucosome clusters regulate the direction of ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-20348-7

    authors: Jeon M,Kang HW,An S

    更新日期:2018-02-09 00:00:00

  • Identification of BST-2/tetherin-induced hepatitis B virus restriction and hepatocyte-specific BST-2 inactivation.

    abstract::BST-2/tetherin is an interferon-inducible antiviral protein that blocks the release of various enveloped viruses, including HIV-1. Hepatitis B virus (HBV), a major cause of liver disease, belongs to the Hepadnaviridae family of enveloped DNA viruses. Whether BST-2 regulates HBV production is largely unknown. In this r...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11736

    authors: Lv M,Zhang B,Shi Y,Han Z,Zhang Y,Zhou Y,Zhang W,Niu J,Yu XF

    更新日期:2015-06-29 00:00:00

  • On the importance of full-dimensionality in low-energy molecular scattering calculations.

    abstract::Scattering of H2 on CO is of great importance in astrophysics and also is a benchmark system for comparing theory to experiment. We present here a new 6-dimensional potential energy surface for the ground electronic state of H2-CO with an estimated uncertainty of about 0.6 cm(-1) in the global minimum region, several ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28449

    authors: Faure A,Jankowski P,Stoecklin T,Szalewicz K

    更新日期:2016-06-23 00:00:00