Nanocarrier-mediated delivery of α-mangostin for non-surgical castration of male animals.

abstract：:Selective pressure from pathogens is considered a key selective force driving the evolution of components of the immune system. Since single components of the immune system may interact with many pathogens, and single pathogens may be recognized by multiple components of the immune system, gaining a better understandi...

journal_title：Scientific reports

authors： Kloch A,Wenzel MA,Laetsch DR,Michalski O,Bajer A,Behnke JM,Welc-Falęciak R,Piertney SB

更新日期：2018-05-30 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep30212. ...

journal_title：Scientific reports

authors： Xu H,Chen X,Xu X,Shi R,Suo S,Cheng K,Zheng Z,Wang M,Wang L,Zhao Y,Tian B,Hua Y

更新日期：2017-05-26 00:00:00

abstract：:Previous studies on the associations between dietary antioxidant vitamins and the risk of cervical cancer remain inconsistent, and little evidence is available for serum antioxidant vitamins, which provide more accurate measurements of these nutrients. We conducted a case-control study of 458 incident cases with invas...

journal_title：Scientific reports

authors： Guo L,Zhu H,Lin C,Che J,Tian X,Han S,Zhao H,Zhu Y,Mao D

更新日期：2015-09-04 00:00:00

abstract：:The Snail transcription factor plays as a master regulator of epithelial mesenchymal transition (EMT), one of the steps of tumor metastasis. Snail enhances expressions of a lot of mesenchymal genes including the matrix degradation enzyme matrix metalloproteinases 9 (MMP9) and the EMT transcription factor zinc finger E...

journal_title：Scientific reports

authors： Wu WS,You RI,Cheng CC,Lee MC,Lin TY,Hu CT

更新日期：2017-12-19 00:00:00

abstract：:Silver-based antibacterial agents have obtained wide attention due to the fact that bacteria in the environment is ubiquitous, which has become one of the most difficult problems for human health. However, the antibacterial mechanism and process are still inconclusive. Here, Ag2O nanoparticles (NPs) with uniform spher...

journal_title：Scientific reports

authors： Li D,Chen S,Zhang K,Gao N,Zhang M,Albasher G,Shi J,Wang C

更新日期：2021-01-18 00:00:00

abstract：:The presence of non-poplar extracts, cutin, and wax layer in the wheat straw outer surface (WOS) greatly limit its application in bio-composite preparation. In this study, a dielectric-barrier-discharge plasma using water vapor as feeding gas was used to fast modify the WOS. The morphology, free radical concentrations...

journal_title：Scientific reports

authors： Chen W,Xu Y,Shi S,Cao Y,Chen M,Zhou X

更新日期：2018-02-02 00:00:00

abstract：:We have studied both experimentally and theoretically the reprogrammable spin wave band structure in Permalloy(10 nm)/Cu(5 nm)/Permalloy(30 nm) nanowire arrays of width w = 280 nm and inter-wire separation in the range from 80 to 280 nm. We found that, depending on the inter-wire separation, the anti-parallel configur...

journal_title：Scientific reports

authors： Gubbiotti G,Zhou X,Haghshenasfard Z,Cottam MG,Adeyeye AO,Kostylev M

更新日期：2019-03-15 00:00:00

abstract：:Transport of tissue-derived lymphatic fluid and clearance by draining lymph nodes are pivotal for maintenance of fluid homeostasis in the body and for immune-surveillance of the self- and non-self-proteomes. Yet a quantitative analysis of nodal filtration of the tissue-derived proteome present in lymphatic fluid has n...

journal_title：Scientific reports

authors： Clement CC,Wang W,Dzieciatkowska M,Cortese M,Hansen KC,Becerra A,Thangaswamy S,Nizamutdinova I,Moon JY,Stern LJ,Gashev AA,Zawieja D,Santambrogio L

更新日期：2018-07-26 00:00:00

abstract：:Junction-less nanowire transistors are being investigated to solve short channel effects in future CMOS technology. Here we demonstrate 8 nm diameter silicon nanowire junction-less transistors with metallic doping densities which demonstrate clear 1D electronic transport characteristics. The 1D regime allows excellent...

journal_title：Scientific reports

authors： Mirza MM,Schupp FJ,Mol JA,MacLaren DA,Briggs GAD,Paul DJ

更新日期：2017-06-07 00:00:00

abstract：:Excessive alcohol consumption leads to overproduction of urates and renal function plays a critical role in serum uric acid levels. We aimed to assess associations of hyperuricemia in patients with alcohol use disorder (AUD) and comparable Glomerular Filtration Rate (GFR). A total of 686 patients undergoing treatment ...

journal_title：Scientific reports

authors： Hernández-Rubio A,Sanvisens A,Bolao F,Pérez-Mañá C,García-Marchena N,Fernández-Prendes C,Muñoz A,Muga R

更新日期：2020-11-18 00:00:00

abstract：:Full-endoscopic transforaminal lumbar discectomy (FETD) is increasingly used in patients with lumbar disc herniation (LDH). There is little knowledge on the related factors, including the straight leg raising test (SLR), that influence the operation. Consecutive patients with LDH who came to our hospital from August 2...

journal_title：Scientific reports

authors： Wei FL,Gao H,Yan X,Yuan Y,Qian S,Gao Q,Guo S,Xue W,Qian J,Zhou C

更新日期：2020-10-05 00:00:00

abstract：:A bioelectronic nose device based on micelle-stabilized olfactory receptors is developed for the selective discrimination of a butter flavor substance in commercial fermented alcoholic beverages. In this work, we have successfully overexpressed ODR-10, a type of olfactory receptor, from Caenorhabditis elegans using a ...

journal_title：Scientific reports

authors： Shin N,Lee SH,Pham Ba VA,Park TH,Hong S

更新日期：2020-06-03 00:00:00

abstract：:The objective of the study was to estimate if altered levels of alpha-synuclein can be detected in tear fluid of patients with Parkinson's disease (PD). Therefore, tear fluid samples of 75 PD patients, 75 control subjects and 31 atypical Parkinsonian patients were collected and analyzed in triplicates using an ultra-s...

journal_title：Scientific reports

authors： Maass F,Rikker S,Dambeck V,Warth C,Tatenhorst L,Csoti I,Schmitz M,Zerr I,Leha A,Bähr M,Lingor P

更新日期：2020-05-22 00:00:00

abstract：:GPR88 is an orphan G-protein-coupled receptor with predominant expression in reward-related areas in the brain. While the lack of GPR88 has been demonstrated to induce behavioral deficits, the potential function of the receptor in the control of food intake and energy balance remains unexplored. In this work, the role...

journal_title：Scientific reports

authors： Lau J,Farzi A,Enriquez RF,Shi YC,Herzog H

更新日期：2017-08-30 00:00:00

abstract：:The global increase in Diabetes Mellitus (DM) has led to an increase in DM-Chronic Kidney Disease (DM-CKD). In this cross-sectional observational study we aimed to define phenotypes for patients with DM-CKD that in future may be used to individualise treatment We report 4 DM-CKD phenotypes in 220 patients recruited fr...

journal_title：Scientific reports

authors： Montero RM,Herath A,Qureshi A,Esfandiari E,Pusey CD,Frankel AH,Tam FWK

更新日期：2018-01-08 00:00:00

abstract：:Oceanic vortices are ubiquitous in the ocean. They dominate the sub-inertial energy spectrum, and their dynamics is key for the evolution of the water column properties. The merger of two like-signed coherent vortices, which ultimately results in the formation of a larger vortex, provides an efficient mechanism for th...

journal_title：Scientific reports

authors： de Marez C,Carton X,L'Hégaret P,Meunier T,Stegner A,Le Vu B,Morvan M

更新日期：2020-02-19 00:00:00

abstract：:Aerogels have numerous applications due to their high surface area and low densities. However, creating aerogels from a large variety of materials has remained an outstanding challenge. Here, we report a new methodology to enable aerogel production with a wide range of materials. The method is based on the assembly of...

journal_title：Scientific reports

authors： Jung SM,Jung HY,Dresselhaus MS,Jung YJ,Kong J

更新日期：2012-01-01 00:00:00

abstract：:The global loss of biodiversity can be attributed to numerous threats. While pioneer studies have investigated their relative importance, the majority of those studies are restricted to specific geographic regions and/or taxonomic groups and only consider a small subset of threats, generally in isolation despite their...

journal_title：Scientific reports

authors： Leclerc C,Courchamp F,Bellard C

更新日期：2018-04-23 00:00:00

abstract：:The increasing demand for healthy baked goods boosted studies on sourdough microbiota with beneficial metabolic traits, to be used as potential functional starters. Here, 139 yeasts isolated from cereal-based fermented foods were in vitro characterized for their phytase and antioxidant activities. The molecular charac...

journal_title：Scientific reports

authors： Palla M,Blandino M,Grassi A,Giordano D,Sgherri C,Quartacci MF,Reyneri A,Agnolucci M,Giovannetti M

更新日期：2020-07-30 00:00:00

abstract：:Accumulating evidence indicates the association between obesity and lung function. However, no previous study has examined whether obesity affects lung function in normal weight participants with high body fat. We hypothesized that subjects with normal weight obesity (NWO) were inversely associated with lung function ...

journal_title：Scientific reports

authors： Chen YY,Kao TW,Fang WH,Wang CC,Chang YW,Yang HF,Wu CJ,Sun YS,Chen WL

更新日期：2019-06-20 00:00:00

abstract：:Among the III-nitride semiconductors, InxGa1-xN is a key material for visible optical devices such as light-emitting diodes (LEDs), laser diodes, and solar cells. Light emission is achieved via electron-hole recombination within the InxGa1-xN layer. When InxGa1-xN-based blue LEDs were first commercialized, the high pr...

journal_title：Scientific reports

authors： Sakaki A,Funato M,Miyano M,Okazaki T,Kawakami Y

更新日期：2019-03-06 00:00:00

abstract：:MicroRNAs (miRNAs) have been reported to be involved in DNA damage response induced by ionizing radiation (IR). c-Myc is reduced when cells treated with IR or other DNA damaging agents. It is unknown whether miRNAs participate in c-Myc downregulation in response to IR. In the present study, we found that miR-449a enha...

journal_title：Scientific reports

authors： Mao A,Zhao Q,Zhou X,Sun C,Si J,Zhou R,Gan L,Zhang H

更新日期：2016-06-02 00:00:00

abstract：:Melamine detection has attracted much attention since the discovery of the damage of melamine to human health. Herein, we have developed a sensitive homogeneous electroanalytical platform for melamine detection, which is relied on the formation of triplex molecular beacon integrated with exonuclease III (Exo III)-medi...

journal_title：Scientific reports

authors： Liu X,Song M,Li F

更新日期：2017-07-03 00:00:00

abstract：:Traumatic brain injury (TBI) is a frequent cause of chronic headache, fatigue, insomnia, hyperactivity, memory deficits, irritability and posttraumatic stress disorder. Recent evidence suggests beneficial effects of pro-cannabinoid treatments. We assessed in mice levels of endocannabinoids in association with the occu...

journal_title：Scientific reports

authors： Vogel A,Wilken-Schmitz A,Hummel R,Lang M,Gurke R,Schreiber Y,Schäfer MKE,Tegeder I

更新日期：2020-09-10 00:00:00

abstract：:Chronic wounds affect millions of patients around the world and their treatment is challenging as the early signs indicating their development are subtle. In addition, a type of chronic wound, known as pressure ulcer, develops in patients with limited mobility. Infection and frequent bleeding are indicators of chronic...

journal_title：Scientific reports

authors： Farooqui MF,Shamim A

更新日期：2016-06-29 00:00:00

abstract：:Dickeya zeae is the causal agent of rice foot rot disease, which has recently become a great threat to rice planting countries and regions. The pathogen produces a family of phytotoxins named zeamines that is critical for bacterial virulence, but little is known about the signaling pathways and regulatory mechanisms t...

journal_title：Scientific reports

authors： Lv M,Chen Y,Liao L,Liang Z,Shi Z,Tang Y,Ye S,Zhou J,Zhang L

更新日期：2018-01-10 00:00:00

abstract：:Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cancer efficacy and lower side effects than Cos or Dehy alone in vivo, however, their anti-cancer molecular mech...

journal_title：Scientific reports

authors： Peng Z,Wang Y,Fan J,Lin X,Liu C,Xu Y,Ji W,Yan C,Su C

更新日期：2017-01-24 00:00:00

abstract：:Multidrug-resistant pathogens causing nosocomial and community acquired infections delineate a significant threat to public health. It had urged to identify new antimicrobials and thus, generated interest in studying macrocyclic metal complex, which has been studied in the past for their antimicrobial activity. Hence,...

journal_title：Scientific reports

authors： Brahma U,Kothari R,Sharma P,Bhandari V

更新日期：2018-05-23 00:00:00

abstract：:Myocardial ischemia/reperfusion (I/R) injury detrimentally alters the prognosis of patients undergoing revascularization after acute myocardial infarction. Our previous study demonstrated that NF-κB-induced autophagy plays a detrimental role in cardiac I/R injury using a rabbit myocardial I/R model. In this study, we ...

journal_title：Scientific reports

authors： Zeng M,Wei X,Wu Z,Li W,Zheng Y,Li B,Meng X,Fu X,Fei Y

更新日期：2016-11-18 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) threw lights on heart failure treatment, however, parts of patients showed nonresponse to CRT. Unfortunately, it lacks effective parameters to predict CRT non-response. In present study, we try to seek effective electro-echocardiographic predictors on CRT non-response. This is a...

journal_title：Scientific reports

authors： Yu Z,Chen X,Han F,Qin S,Li M,Wu Y,Su Y,Ge J

更新日期：2017-03-10 00:00:00