An adult female with headache and bilateral shank ache.

abstract：INTRODUCTION:Children's obesity is a known health problem in the world and is a strong predictor of obesity in adulthood which increases the incidence of related diseases such as metabolic syndrome. According to the MONIKA project by the World Health Organization (WHO), Iran is one of the seven countries with a high ra...

journal_title：Endokrynologia Polska

authors： Adibi A,Kelishadi R,Beihaghi A,Salehi H,Talaei M

更新日期：2009-01-01 00:00:00

abstract：:Among genetic alterations most important for the initiation of papillary thyroid carcinoma (PTC) is mutation T1799A in the BRAF gene which is the most frequent event (54.5%) in this type of thyroid cancer. It is seen in all stages, from microcarcinoma through clinically overt disease to anaplastic cancer. It has been ...

journal_title：Endokrynologia Polska

authors： Rusinek D,Gubała E

更新日期：2006-07-01 00:00:00

abstract：:The study was aimed at the assessment of frequency of occurrence of thyroid antimicrosomal and antithyreoglobuln autoantibodies in children with insulin-dependent diabetes and healthy control children. The occurrence of thyroid autoantibodies was analyzed with respect to the age and sex of children and the duration of...

journal_title：Endokrynologia Polska

authors： Smorawińska A,Walczak M,Korman E,Lacka K,Smorawinski J

更新日期：1989-01-01 00:00:00

abstract：INTRODUCTION:The predominance of high-molecular-weight forms of prolactin in plasma is referred to as macroprolactinaemia. Unlike monomeric hyperprolactinaemia, no previous study has investigated cardiometabolic risk factors in subjects with elevated macroprolactin content. MATERIAL AND METHODS:We studied two age-, we...

journal_title：Endokrynologia Polska

authors： Krysiak R,Marek B,Okopień B

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Considering the high prevalence of congenital hypothyroidism (CH) in Isfahan, it seems that it is necessary to investigate the aetiology of the disorder and its related factors. The aim of this study was to determine the aetiology of CH among children in Isfahan province. MATERIAL AND METHODS:In this cros...

journal_title：Endokrynologia Polska

authors： Hoseini M,Hekmatnia A,Hashemipour M,Basiratnia R,Omidifar N,Rezazade A,Koohi R

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Since the effect of pre-therapeutic scintigraphy on the outcome of DTC treatment is debated, we evaluated factors affecting the effectiveness of (131)I therapy with respect to the delay between diagnostic scintigraphy and the application of radioiodine. MATERIAL AND METHODS:In the studied group of 60 pati...

journal_title：Endokrynologia Polska

authors： Bałdys-Waligórska A,Buziak-Bereza M,Huszno B,Wilczak A

更新日期：2006-07-01 00:00:00

abstract：INTRODUCTION:The overexpression of nitric oxide synthase (NOS) has been found in tumours, including pituitary adenomas. It has also been found that NOS is overexpressed in human spontaneous pituitary adenomas. The question arises whether NOS and its product, nitric oxide (NO), are involved in pituitary tumourigenesis. ...

journal_title：Endokrynologia Polska

authors： Pawlikowski M,Pisarek H,Fryczak J,Stępień H

更新日期：2012-01-01 00:00:00

abstract：:Hormony tarczycy (thyroid hormones, TH) są zaangażowane w wiele różnych procesów biologicznych, wliczając rozwój układu nerwowego, regulację metabolizmu pośredniego oraz zużycie energii. Aktywnie uczestniczą w podstawowym zużyciu energii i termogenezie adaptacyjnej i z tego względu mogą mieć wpływ na masę ciała w prze...

journal_title：Endokrynologia Polska

authors： García-Solís P,García OP,Hernández-Puga G,Sánchez-Tusie AA,Sáenz-Luna CE,Hernández-Montiel HL,Solis-S JC

更新日期：2018-01-01 00:00:00

abstract：:Immunotherapy using monoclonal antibodies - checkpoint inhibitors - is a dynamically evolving discipline of clinical oncology and a new hope for patients with advanced and disseminated cancer. However, the activation of T-lymphocytes can at the same time lead to autoimmune response and destruction of healthy organs, w...

journal_title：Endokrynologia Polska

authors： Król A,Gawlik T,Jarząb B

更新日期：2018-01-01 00:00:00

abstract：:Increased interest in vitamin D measurements in clinical studies has contributed to the development in recent years of several new immunochemical assays (manual and for automatic analyzers). New methods, including HPLC (high performance liquid chromatography), and LC-MS/MS (liquid chromatography coupled with tandem ma...

journal_title：Endokrynologia Polska

authors： Bartoszewicz Z,Kondracka A,Jaźwiec R,Popow M,Dadlez M,Bednarczuk T

更新日期：2013-01-01 00:00:00

abstract：:Many mechanism may participate in the inhibition of thyroid function by excess of iodine. The present study was aimed at answering the question, whether the excess of iodine influences the activity of type I thyroxine 5'-deiodinase. To 40 female rats fed with standard diet a dose of 42 micrograms of iodine daily was a...

journal_title：Endokrynologia Polska

authors： Bednarczuk T,Pietrzykowski A,Słoń M,Nauman A

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:To evaluate the clinical profile of BIAsp 30 (30% soluble insulin aspart, 70% protamine-crystallized insulin aspart) (NovoMix®)30) in type 2 diabetes patients in routine clinical practice in Iran. MATERIAL AND METHODS:IMPROVE™ was a 26-week, multinational, open-label, non-randomized study in patients with...

journal_title：Endokrynologia Polska

authors： Esteghamati A,Rajabian R,Amini M,Bahrami A,Khamseh ME,Afkhami-Ardekani M,Rizi EP

更新日期：2010-07-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) diagnosis and therapy still arouse a lot of controversy. Each year brings new information, so, having collected the experience of three scientific societies, we present contemporary recommendations concerning PCOS diagnostics and treat-ment. In adult female diagnosis, we still use the ...

journal_title：Endokrynologia Polska

authors： Milewicz A,Kudła M,Spaczyński RZ,Dębski R,Męczekalski B,Wielgoś M,Ruchała M,Małecka-Tendera E,Kos-Kudła B,Jędrzejuk D,Zachurzok A

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:In order to be effective, treatment for osteoporosis must be long-term. Unfortunately, according to clinical trials and clinical practice the most frequent cause of patient resignation from the treatment is adverse reactions to the medications. In the case of bisphosphonates they are most frequently connec...

journal_title：Endokrynologia Polska

authors： Jastrzebski Z,Napiórkowska L,Pykało R

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The activity of androgen receptor (AR) is modulated by a polymorphic region located within exon 1 its gene and characterizing a variable number of trinucleotide CAG repeats. The length of polymorphic region is inversely correlated with the transactivation function of AR gene. It was showed an ethnic differen...

journal_title：Endokrynologia Polska

authors： Filus A,Medraś M,Kuliczkowska-Płaksej J,Trzmiel-Bira A,Laczmański L,Jedrzejuk D

更新日期：2009-07-01 00:00:00

abstract：:Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all d...

journal_title：Endokrynologia Polska

authors： Starzyńska T,Deptała A,Królicki L,Kunikowska J,Londzin-Olesik M,Nasierowska-Guttmejer A,Ruchała M,Strzelczyk J,Szawłowski A,Zgliczyński W,Kos-Kudła B,Consensus Conference.,Polish Network of Neuroendocrine Tumours.

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies and constitutes approximately 1.6-5% of the malignant neoplasms of the thyroid gland. ATC usually manifests itself with the local symptoms due to a rapidly enlarging thyroid mass, and as other thyroid cancers, has only seld...

journal_title：Endokrynologia Polska

authors： Daroszewski J,Paczkowska K,Jawiarczyk-Przybyłowska A,Bolanowski M,Jeleń M

更新日期：2018-01-01 00:00:00

abstract：:Acromegaly is usually caused by excess GH (growth hormone) secretion by pituitary adenoma. Extremely rare (< 1% of cases) acromegaly can be a result of ectopic GHRH (growth hormone releasing hormone) secretion by bronchial tubes, lung, pancreatic or intestinal tumor. The aim of this description is to present the case ...

journal_title：Endokrynologia Polska

authors： Bolanowski M,Kos-Kudła B,Rzeszutko M,Marciniak M,Zatońska K

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:In the current study, we evaluated the accuracy of sentinel node mapping in thyroid cancer patients using both radiotracer and blue dye. MATERIAL AND METHODS:30 patients with a diagnosis of papillary thyroid carcinoma (PTC) were included in the study; 2-3 hours before surgery, 0.5 mCi 99m-Tc-Antimony Sulf...

journal_title：Endokrynologia Polska

authors： Assadi M,Yarani M,Zakavi SR,Jangjoo A,Memar B,Treglia G,Aliakbarian M,Mehrabibahar M,Sadeghi R

更新日期：2014-01-01 00:00:00

abstract：:Renalase is a recently identified flavoprotein oxidase, secreted mainly by the kidneys, which takes part in the degradation of catecholamines. The catecholamine inactivating effect results in the modulation of the sympathetic system tension and, consequently, in a decrease of blood pressure, myocardial contractility, ...

journal_title：Endokrynologia Polska

authors： Czubilińska-Łada J,Gliwińska A,Badeński A,Szczepańska M

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Fine needle aspiration biopsy (FNAB) is the main examination in diagnostics of thyroid nodules. Yet, it does not allow the differentiation of follicular lesions (FL). A new classification of thyroid biopsy results (newC) might improve pre-operative diagnostics mainly due to the introduction of a new subcat...

journal_title：Endokrynologia Polska

authors： Woźniak-Oseła E,Popowicz B,Sporny S,Klencki M,Słowińska-Klencka D

更新日期：2014-01-01 00:00:00

abstract：:Most medical agents currently applied in osteoporosis therapy act by inhibiting bone resorption and reducing bone remodelling, i.e. they inhibit the process of bone mass loss by suppressing bone resorption processes. These drugs provide an ideal therapeutic option to prevent osteoporosis progression. They however have...

journal_title：Endokrynologia Polska

authors： Misiorowski W

更新日期：2011-01-01 00:00:00

abstract：:There is a growing number of diseases which prevalence can be associated with vitamin D deficiency. The link between low cholecalciferol concentration and bone diseases is well established, however there is also data suggesting that it may influence development and progression of different cancers and autoimmune disea...

journal_title：Endokrynologia Polska

authors： Kuryłowicz A,Bednarczuk T,Nauman J

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Adrenal pheochromocytoma are diagnosed the most often in patients with arterial hypertension or with thyroid medullar cancer and suspicion of MEN II syndromes. The aim of the study is to analyse the morphology of pheochromocytomas on the basis of Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) in o...

journal_title：Endokrynologia Polska

authors： Kajor M,Ziaja J,Lange D,Król R,Ciupińska-Kajor M,Turska-d'Amico M,Maka B,Cierpka L

更新日期：2005-11-01 00:00:00

abstract：INTRODUCTION:The clinical usefulness of baroreflex sensitivity (BRS) in the early detection of autonomic dysfunction in patients with diabetes is not well established. The aim of the study was the evaluation of BRS in subjects with type 1 diabetes with and without cardiovascular autonomic neuropathy (CAN). MATERIAL AN...

journal_title：Endokrynologia Polska

authors： Kamińska A,Tafil-Klawe M,Smietanowski M,Bronisz A,Ruprecht Z,Klawe J,Junik R

更新日期：2008-09-01 00:00:00

abstract：:Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are often used by athletes as doping agents. It is estimated that up to 25% of sportsmen using anabolic-androgenic steroids also take GH. Available data do not confirm the influence of GH or IGF-1 preparations on physical performance improvement. However, th...

journal_title：Endokrynologia Polska

authors： Jóźków P,Medraś M

更新日期：2009-09-01 00:00:00

abstract：:Questionnaire, clinical, ultrasonographic and biochemical studies (determination of urinary iodine concentration) have been carried out in 1686 children of age between 7 and 13 years living in the Lublin Upland region. The presence of goiter was found in 368 children (21.8%). A gradual increase in the incidence of goi...

journal_title：Endokrynologia Polska

authors： Szewczyk L,Beń-Skowronek I,Jaklińska T,Lozowski C

更新日期：1993-01-01 00:00:00

abstract：:The genetic risk of differentiated thyroid cancer (DTC) probably consists of multiple low-penetrance, single-nucleotide polymorphisms (SNP). Such markers are difficult to uncover by linkage analysis but can be revealed by association studies. Genome-wide association studies (GWASs) have uncovered 31 SNPs associated wi...

journal_title：Endokrynologia Polska

authors： Jendrzejewski JP,Sworczak K,Comiskey DF,de la Chapelle A

更新日期：2019-01-01 00:00:00

abstract：:We describe a 37 year-old woman case of latent autoimmune diabetes in adults (LADA). She was presented with unfounded weight loss. The diagnosis of diabetes mellitus was established on twice plasma glucose measurements above 200 mg/dl. In other routine biochemical examinations we did not observe dehydratation, electro...

journal_title：Endokrynologia Polska

authors： Szepietowska B,Szelachowska M,Górska M

更新日期：2006-05-01 00:00:00

abstract：INTRODUCTION:Patients with Addison's disease experience many somatic and psychic changes, which decrease their quality of life. The aim of the study was to evaluate the "psychological equipment" of these patients to cope with stress connected with this chronic disease and the challenge of constant treatment. MATERIAL ...

journal_title：Endokrynologia Polska

authors： Warmuz-Stangierska I,Baszko-Błaszyk D,Sowiński J

更新日期：2010-01-01 00:00:00