Abstract：
:Polycystic ovary syndrome (PCOS) diagnosis and therapy still arouse a lot of controversy. Each year brings new information, so, having collected the experience of three scientific societies, we present contemporary recommendations concerning PCOS diagnostics and treat-ment. In adult female diagnosis, we still use the Rotterdam criteria, which is two out of three of the follwing characteristics: a) ovulation abnormality, b) clinical or biochemical hyperandrogenism, and c) polycystic ovaries. In the case of teenagers, diagnostic criteria are as follows: menstruation disturbances two years after menarche and clinical or biochemical hyperandrogenism. The presence of polycysti-cally abnormal ovaries is not necessary. The consensus paper presents the threats resulting from imperfect diagnostic methods applied in PCOS (hyperandrogenism diagnostics, ultrasound examination of ovaries). Suggested therapy includes personalised schemes according to the dominant PCOS phenotype, i.e. metabolic, hyperandrogenic, or reproductive ones.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Milewicz A,Kudła M,Spaczyński RZ,Dębski R,Męczekalski B,Wielgoś M,Ruchała M,Małecka-Tendera E,Kos-Kudła B,Jędrzejuk D,Zachurzok Adoi
10.5603/EP.2018.0046subject
Has Abstractpub_date
2018-01-01 00:00:00issue
4eissn
0423-104Xissn
2299-8306pii
VM/OJS/J/59162journal_volume
69pub_type
杂志文章,实务指引abstract：INTRODUCTION:An increased risk of mortality in patients with uncontrolled acromegaly has been reported in several studies. We aimed to assess the impact of co-morbidities on the survival of patients with acromegaly after long-term treatment and follow-up. MATERIAL AND METHODS:A retrospective analysis was performed for...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.a2016.0031
更新日期：2016-01-01 00:00:00
abstract：:Primary aldosteronism is the commonest form of hormone-related hypertension, with an estimated prevalence of 6-13% in the generalpopulation of hypertensive patients. Among patients with resistant hypertension, the proportion of PA is even higher. Through intensiveresearch in the field of basic science and the creation...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：10.5603/ep.2013.0011
更新日期：2013-01-01 00:00:00
abstract：INTRODUCTION:Over the last decade, average life expectancy has continuously increased. There has been no data on normal sex hormone (SH) levels in a Polish elderly population. In this study, we assessed SH in the PolSenior cohort to determine normal reference ranges in relation to gender, age, and cardiovascular diseas...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are often used by athletes as doping agents. It is estimated that up to 25% of sportsmen using anabolic-androgenic steroids also take GH. Available data do not confirm the influence of GH or IGF-1 preparations on physical performance improvement. However, th...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2009-09-01 00:00:00
abstract：INTRODUCTION:Secondary hyperparathyroidism (sHPT) is one of the most common abnormalities found in patients with chronic kidney disease (CKD). Measurement of serum PTH concentrations is crucial in diagnosis and treatment of sHPT. Different methods of serum PTH measurement may provide diverse results. This may have a si...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.2015.0028
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate the number of women who take multivitamin formulations containing iodine. MATERIAL AND METHODS:A 34-question questionnaire was given to 500 women during their puerperal stay in two obstetrics/gynaecology wards in Krakow. RESULTS:295 pregnant women (59%) took iodine-con...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Endocrine Society has recently published recommendations on the diagnosis and management of PA. Due to the fact that the cu...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:Generally, squamous cell carcinoma carries a poor prognosis because of its tendency to local invasion and subsequent metastasis, which is mediated by multiple factors and angiogenesis. Hepatocyte growth factor (HGF) is a potent mitogen for epithelial cells and regulates cell proliferation and migration and...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：INTRODUCTION:Surgeries that spare the adrenal cortex during adrenalectomy have profound justification. Indications for this type of surgery are fairly strict, and more than 30 years of observations continuously verify the results of the procedure. MATERIAL AND METHODS:Of a total of 650 adrenalectomies, 22 (3.4%) were ...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.a2020.0033
更新日期：2020-01-01 00:00:00
abstract：:A group of 153 patients with scintigraphically detected autonomic "hot" nodules of the thyroid has been subjected to clinical and histopathological analysis. Substantial part of these patients (30.1%) had hyperthyroidism, partly (in 19.9% of cases) in the form of the thyrocardiac syndrome. A most frequent histopatholo...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND:Adrenal pheochromocytoma are diagnosed the most often in patients with arterial hypertension or with thyroid medullar cancer and suspicion of MEN II syndromes. The aim of the study is to analyse the morphology of pheochromocytomas on the basis of Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) in o...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：INTRODUCTION:Oxytocin might be used therapeutically as an ally to rescue osteopathy resulting from diabetes. However, the in vivo effects of oxytocin on marrow adipogenesis in diabetes remain unknown. In this longitudinal study, we aimed to investigate the protective ef-fects of oxytocin on diabetes-induced marrow adip...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.a2018.0040
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Chronic psychological distress can cause suppression of the hypothalamic-pituitary-testicular axis and thus lead to male hypogonadism, which is associated with psycho-social dysfunction, chronic diseases, and as a result, considerable economic costs. Conversely, noise is a prototypal environmental stressor...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,meta分析,评审
doi：10.5603/EP.2015.0007
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:After thyroidectomy and radioiodine therapy, patients with differentiated thyroid cancer (DTC) are indefinitely treated with levothyroxine (L-T4). Osteoporosis is a debated consequence of hypothyroxinaemia. The aim of this study was to evaluate bone mineral density (BMD) and fracture risk assessed by FRAX ...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.a2016.0046
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Fine needle aspiration biopsy (FNAB) of the thyroid nodules generally allows to make the diagnosis and to choose the proper clinical management. In about 10% of cases cytopathologic features do not differentiate unequivocally benign and malignant lesions. In these cases the cytopathologic diagnosis of foll...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:According to the socio-sexological reports approximately 40-45% of women and up to 30% of males may suffer from different sexual dysfunctions. The prevalence of those disorders is gradually increasing with age. Multiply numbers of endocrinopathies may influence the human sexual life. In diabetic patients all phases of...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-11-01 00:00:00
abstract：INTRODUCTION:Aim of the study was present personal observations connected with the management of patients referred to surgical treatment for secondary hyperparathyroidism (SHT) or tertiary hyperparathyroidism (THT), and to assess immediate results of such management. MATERIAL AND METHODS:A total of 175 patients aged 2...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：:Acromegaly is usually caused by excess GH (growth hormone) secretion by pituitary adenoma. Extremely rare (< 1% of cases) acromegaly can be a result of ectopic GHRH (growth hormone releasing hormone) secretion by bronchial tubes, lung, pancreatic or intestinal tumor. The aim of this description is to present the case ...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:Follicular Lesion of Undetermined Significance (FLUS) belongs to the most controversial category of the Bethesda System. The aim of the study was to specify the risk of malignancy in patients with FLUS diagnosis in the material from the Institute of Oncology in Gliwice. This is the first Polish study speci...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.2016.0002
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Omentin-1, secreted by visceral adipose tissue, has been indicated in the regulation of bone metabolism in girls with anorexia nervosa (AN). The aim of the study was to evaluate the relationship between omentin-1 and bone metabolism in girls with AN as well as the potential involvement of OPG and RANKL in ...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：10.5603/EP.2015.0063
更新日期：2015-01-01 00:00:00
abstract：:The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the freque...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：:The hormone leptin is secreted from white adipocytes, and serum levels of leptin correlate with adipose tissue mass. Leptin was first described as acting on the satiety centre in the hypothalamus through specific receptors (ob-R) to restrict food intake and enhance energy expenditure. Leptin plays a crucial role in th...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：:The aim of immunohistochemistry and immunocytochemistry is to reveal specific antigens in cells and tissue samples. Those techniques are based on an antigen-antibody reaction and visualization of its product in microscopic examination. The precursor of this new diagnostic procedure was an immunofluorescent reaction in...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-05-01 00:00:00
abstract：:Many mechanism may participate in the inhibition of thyroid function by excess of iodine. The present study was aimed at answering the question, whether the excess of iodine influences the activity of type I thyroxine 5'-deiodinase. To 40 female rats fed with standard diet a dose of 42 micrograms of iodine daily was a...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The World Health Organization (WHO) issued a recommendation (Technical Consultation: Paris 2006, Luxembourg 2007) that salt consumption, as a risk factor for hypertension, atherosclerosis, myocardial infarction, stroke, and select cancers, should be restricted. The European Commission looked to adhere to this recommen...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:Acromegaly can be treated with several medical modalities. The growth hormone (GH) receptor antagonist pegvisomant, in particular, is able to reduce serum insulin-like growth factor I (IGF-I) concentrations to almost any desired level. Along with this important achievement come other practical issues. The most importa...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-07-01 00:00:00
abstract：:The process of angiogenesis in a heart muscle is a way of providing the ischaemic myocardium with oxygen and nutritive ingredients. This natural process called therapeutic angiogenesis has been tried in the treatment of patients with coronary artery disease mainly. It has been seen as a chance of an effective benefici...
journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-09-01 00:00:00
abstract：INTRODUCTION:Thyroid hormone disorders in patients with chronic kidney disease (CKD) are a result of impaired conversion of T4 to T3. The importance of kidneys in thyroid hormones conversion is not fully understood. The activities of different types of iodothyronine deiodinases in the kidney structures have not been de...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Questionnaire, clinical, ultrasonographic and biochemical studies (determination of urinary iodine concentration) have been carried out in 1686 children of age between 7 and 13 years living in the Lublin Upland region. The presence of goiter was found in 368 children (21.8%). A gradual increase in the incidence of goi...
journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all d...
journal_title：Endokrynologia Polska
pub_type： 共识发展会议,杂志文章,实务指引
doi：10.5603/EP.2013.0032
更新日期：2013-01-01 00:00:00
