Abstract:
:Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are often used by athletes as doping agents. It is estimated that up to 25% of sportsmen using anabolic-androgenic steroids also take GH. Available data do not confirm the influence of GH or IGF-1 preparations on physical performance improvement. However, there is some evidences for many adverse effects in athletes using this form of doping. Blood tests to detect growth hormone abuse are available since several years. Surprisingly, no one has been proven to use illegal doping agents influencing GH/IGF-1 axis.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Jóźków P,Medraś Msubject
Has Abstractpub_date
2009-09-01 00:00:00pages
389-94issue
5eissn
0423-104Xissn
2299-8306journal_volume
60pub_type
杂志文章,评审abstract:INTRODUCTION:Although both statins and fibrates have been found to reduce monocyte cytokine release, no study has investigated whether the effect of hypolipidaemic agents depends on age. MATERIAL AND METHODS:This study retrospectively analysed the results of 65 patients with type 2 diabetes and atherogenic dyslipidaem...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2016.0021
更新日期:2016-01-01 00:00:00
abstract::The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the freque...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Considering the high prevalence of congenital hypothyroidism (CH) in Isfahan, it seems that it is necessary to investigate the aetiology of the disorder and its related factors. The aim of this study was to determine the aetiology of CH among children in Isfahan province. MATERIAL AND METHODS:In this cros...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:We evaluated the predictive value of IGF-1 against hGH in the treatment outcome. MATERIAL AND METHODS:A prospective study was undertaken of 47 patients (mean age 41.1 ± 12.9 years; 44 with macroadenoma and 3 with microadenoma), requiring treatment with octreotide LAR (SSLAR) following incomplete surgery. Co...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::Anti-adrenal and anti-pituitary autoantibodies have been determined in 45 patients with autoimmune diseases of the thyroid, including 25 patients with Graves' disease and 20 patients with hypothyroidism of autoimmune origin. The determinations were carried out with the use of solid-phase RIA methods previously develop...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Adrenal pheochromocytoma are diagnosed the most often in patients with arterial hypertension or with thyroid medullar cancer and suspicion of MEN II syndromes. The aim of the study is to analyse the morphology of pheochromocytomas on the basis of Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) in o...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract::In our study we present chosen elements of microarray analysis of gene expression profile in papillary thyroid cancer. The study group included 16 papillary thyroid cancer tissues and 16 corresponding normal tissues. Samples were analyzed on high density oligonucleotide microarrays (GeneChip HG-U133A) which contain 22...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract:INTRODUCTION:Children's obesity is a known health problem in the world and is a strong predictor of obesity in adulthood which increases the incidence of related diseases such as metabolic syndrome. According to the MONIKA project by the World Health Organization (WHO), Iran is one of the seven countries with a high ra...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Many mechanism may participate in the inhibition of thyroid function by excess of iodine. The present study was aimed at answering the question, whether the excess of iodine influences the activity of type I thyroxine 5'-deiodinase. To 40 female rats fed with standard diet a dose of 42 micrograms of iodine daily was a...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Thyroid dysgenesis (TD) is the main cause of congenital hypothyroidism (CH), affecting nearly 1 in 2000-3000 newborns worldwide, as the most common neonatal endocrine disorder. Paired box gene 8 (PAX8), expressed during all stages of thyroid follicular cell, plays a key role in thyroid morphogenesis by a c...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0004
更新日期:2020-01-01 00:00:00
abstract::Epidemiological foundation included: aim of studies, knowledge about epidemiology of thyroid disorders in Poland, evaluation of radioiodine dose accumulated in thyroids of inhabitants of different age living in different par of Poland, information about relative diet iodine deficiency in different parts of Poland and ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:Bone disorders observed commonly after haematopoietic stem cells transplantation (HSCT) can be caused by several factors,but their detailed pathomechanism is still not well known, especially in childhood.The aim of this study was to evaluate: IGF-I, RANKL-OPG system, IL-6, and IL1β levels and their associa...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/ep.2013.0001
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Oxytocin might be used therapeutically as an ally to rescue osteopathy resulting from diabetes. However, the in vivo effects of oxytocin on marrow adipogenesis in diabetes remain unknown. In this longitudinal study, we aimed to investigate the protective ef-fects of oxytocin on diabetes-induced marrow adip...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2018.0040
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:The introduction of the DICOM format in all diagnostic imaging devices allowed co-registering SPECT, CT, MR and other types of biomedical imaging. Fusion can be performed by dedicated hybrid devices or by means of software. The fusion algorithm consists of two steps: coregistration and simultaneous visuali...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::According to the socio-sexological reports approximately 40-45% of women and up to 30% of males may suffer from different sexual dysfunctions. The prevalence of those disorders is gradually increasing with age. Multiply numbers of endocrinopathies may influence the human sexual life. In diabetic patients all phases of...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2005-11-01 00:00:00
abstract:INTRODUCTION:Patients with Addison's disease experience many somatic and psychic changes, which decrease their quality of life. The aim of the study was to evaluate the "psychological equipment" of these patients to cope with stress connected with this chronic disease and the challenge of constant treatment. MATERIAL ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Hormony tarczycy (thyroid hormones, TH) są zaangażowane w wiele różnych procesów biologicznych, wliczając rozwój układu nerwowego, regulację metabolizmu pośredniego oraz zużycie energii. Aktywnie uczestniczą w podstawowym zużyciu energii i termogenezie adaptacyjnej i z tego względu mogą mieć wpływ na masę ciała w prze...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.2018.0032
更新日期:2018-01-01 00:00:00
abstract::The basic data on hyperprolactinemia (i.e. an excess of PRL above a reference laboratory's upper limits), the most common endocrine disorder of the hypothalamic-pituitary axis are given in this review. The following issues are discussed: regulation of prolactin (Prl) secretion, definition of hyperprolactinemia, its et...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2006-11-01 00:00:00
abstract::Numerous members of semaphorins have been widely clarified to be involved in the development of multiple cancers. However, the semaphorin 6B (SEMA6B) has not yet been extensively reported in cancers, especially in thyroid carcinoma. According to the public dataset from TCGA database, we found that the expression of SE...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0072
更新日期:2020-10-30 00:00:00
abstract:INTRODUCTION:The clinical usefulness of baroreflex sensitivity (BRS) in the early detection of autonomic dysfunction in patients with diabetes is not well established. The aim of the study was the evaluation of BRS in subjects with type 1 diabetes with and without cardiovascular autonomic neuropathy (CAN). MATERIAL AN...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract:INTRODUCTION:Fine needle aspiration biopsy (FNAB) is the main examination in diagnostics of thyroid nodules. Yet, it does not allow the differentiation of follicular lesions (FL). A new classification of thyroid biopsy results (newC) might improve pre-operative diagnostics mainly due to the introduction of a new subcat...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2014.0060
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:The potential effect of adipokines on the development of AF is yet to be established. The aim of this study was to investigate the association of baseline serum adipokines with 1) the presence of AF at baseline and 2) future risk of AF development. MATERIAL AND METHODS:The current study is a sub-analysis ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2019.0059
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Prolactin (PRL) exists in human blood in several molecular forms. Macroprolactin (MaPRL), which most often consists of monomeric PRL and immunoglobulin G, has the highest molecular weight but no biological activity. Immunoassays do not distinguish MaPRL from monomeric PRL, what can lead to an incorrect diagn...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::Autoimmune polyglandular syndromes (APS) consist of a variety of endocrine and non-endocrine disorders. The syndromes are complex and their occurrence in life does not follow any pattern. Early detection of such disorders may prevent many serious clinical consequences which are usually a result of delayed diagnosis. W...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2014.0070
更新日期:2014-01-01 00:00:00
abstract::Not required for Clinical Vignette. ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0071
更新日期:2020-01-01 00:00:00
abstract::Obesity and thyroid function are closely related. Thyroid hormones are involved in the regulation of metabolism, thermogenesis, food intake, and fat oxidation. In obese children the most frequent hormonal abnormalities are slight hyperthyrotropinaemia and moderate increases in total T3 and/or fT3 concentrations. Those...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.2017.0007
更新日期:2017-01-01 00:00:00
abstract::The effect of cholecystokinin octapeptide (CCK-8) on basal and TRH-stimulated secretion of TSH was investigated in 67 male Sprague-Dawley rats. Blood for TSH determinations was sampled by cannulation of right heart auricle in urethane narcosis before and four times during 60 minutes following CCK-8 administration. It ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::The genetic risk of differentiated thyroid cancer (DTC) probably consists of multiple low-penetrance, single-nucleotide polymorphisms (SNP). Such markers are difficult to uncover by linkage analysis but can be revealed by association studies. Genome-wide association studies (GWASs) have uncovered 31 SNPs associated wi...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.a2019.0027
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Recently, a new fracture risk-assessment calculator (FRAX) has been introduced. The aim of this study was to assess its usefulness for the re-assessment of fracture risk in obese patients and re-assignment to treatment. MATERIAL AND METHODS:350 obese female patients were included. In all of them, 10-year ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:Poorly differentiated thyroid carcinoma (PDTC, insular carcinoma) occurs rarely. It is described with more aggressive behaviour, poorer prognosis, and higher mortality than well differentiated thyroid carcinoma (WDTC). The aim of this study was to evaluate the clinical course of patients with PDTC, in addi...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00