Abstract:
INTRODUCTION:Considering the high prevalence of congenital hypothyroidism (CH) in Isfahan, it seems that it is necessary to investigate the aetiology of the disorder and its related factors. The aim of this study was to determine the aetiology of CH among children in Isfahan province. MATERIAL AND METHODS:In this cross-sectional study, the aetiology of CH and the volume of the thyroid was assessed using neck ultrasonography. The results of thyroid function screening tests were additionally recorded. The correlation between ultrasonographic findings and the level of TSH and as well as T4 was determined. RESULTS:During this study 385 CH patients aged 0-3 years were studied. According to ultrasonographic findings, in 19.9% of patients the aetiology of CH was dysgenesis (agenesis, ectopy, and hemiagenesis) and 80.1% had normal thyroid. Mean thyroid gland volume in all studied patients was 0.78 ± 0.44 mL. The prevalence of ultrasonographic findings was as follows: normal 80.1%, agenesis 12.7%, hemiagenesis 5.8%, and ectopy 1.4%. There was a significant correlation between thyroid volume and TSH and T4 and as well as between TSH and ultrasonographic findings (p 〈 0.05). CONCLUSIONS:In spite of the limitations of ultrasonography in the field of determining the aetiology of CH, it is an appropriate imaging tool for determining the volume of the thyroid gland in children. Considering that the rate of goitrous gland was low, it seems that iodine deficiency could not be responsible for the high rate of CH in this region.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Hoseini M,Hekmatnia A,Hashemipour M,Basiratnia R,Omidifar N,Rezazade A,Koohi Rsubject
Has Abstractpub_date
2010-11-01 00:00:00pages
665-70issue
6eissn
0423-104Xissn
2299-8306journal_volume
61pub_type
杂志文章abstract:INTRODUCTION:In order to be effective, treatment for osteoporosis must be long-term. Unfortunately, according to clinical trials and clinical practice the most frequent cause of patient resignation from the treatment is adverse reactions to the medications. In the case of bisphosphonates they are most frequently connec...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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更新日期:2007-05-01 00:00:00
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
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journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
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更新日期:2007-07-01 00:00:00
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:Endokrynologia Polska
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更新日期:2018-01-01 00:00:00
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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