What do we know about biomarkers in diabetic kidney disease?

Abstract:

:Diabetic kidney disease (DKD) remains the leading cause of the end-stage renal disease (ESRD) and the most common reason for renal replacement therapy. Research has been carried out for years to find a marker that would enable early identification of people at risk of DKD occurrence, as well as people who will progress from DKD to ESRD. With regard to daily medical practice, the only existing prognostic biomarkers in DKD remain urine albumin-creatinine ratio based on the urinary assessment of albumin and creatinine, and estimated glomerular filtration rate - on the basis of serum creatinine concentration. The development of other biomarkers that would enable the identification of patients at risk of DKD, the stratification of the risk of progression to ESRD, as well as the creation of personalised therapy is currently of great interest. This article discusses selected studies in this field, which have been published in recent years.

journal_name

Endokrynol Pol

journal_title

Endokrynologia Polska

authors

Kwiendacz H,Nabrdalik K,Stompór T,Gumprecht J

doi

10.5603/EP.a2020.0077

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

545-550

issue

6

eissn

0423-104X

issn

2299-8306

pii

VM/OJS/J/70395

journal_volume

71

pub_type

杂志文章
  • [A case associating primary parathyroid hyperfunction with hyperthyroidism].

    abstract::A case of rare association of hyperparathyroidism with fully developed hyperthyroidism appearing in a woman 23 years old with advanced generalized cystic fibrosis has been presented. ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Plamieniak Z,Głebowska-Halawa H,Bednorz W,Komorski A

    更新日期:1992-01-01 00:00:00

  • WHO fracture risk calculator (FRAX) in the assessment of obese patients with osteoporosis.

    abstract:INTRODUCTION:Recently, a new fracture risk-assessment calculator (FRAX) has been introduced. The aim of this study was to assess its usefulness for the re-assessment of fracture risk in obese patients and re-assignment to treatment. MATERIAL AND METHODS:350 obese female patients were included. In all of them, 10-year ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Franek E,Wichrowska H,Gozdowski D,Puzianowska-Kuźnicka M

    更新日期:2009-03-01 00:00:00

  • Colorectal neuroendocrine neoplasms - management guidelines (recommended by the Polish Network of Neuroendocrine Tumours).

    abstract::Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all d...

    journal_title:Endokrynologia Polska

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.5603/EP.2013.0032

    authors: Starzyńska T,Deptała A,Królicki L,Kunikowska J,Londzin-Olesik M,Nasierowska-Guttmejer A,Ruchała M,Strzelczyk J,Szawłowski A,Zgliczyński W,Kos-Kudła B,Consensus Conference.,Polish Network of Neuroendocrine Tumours.

    更新日期:2013-01-01 00:00:00

  • Surgical approach to differentiated thyroid cancers (DTC) in children [Specyfika leczenia chirurgicznego zróżnicowanych raków tarczycy (ZRT) u dzieci].

    abstract::Thyroid cancer in children is rare and accounts for 1-3% of all malignant tumours. Differentiated thyroid cancers (DTC) and particularly papillary thyroid carcinoma (PTC) (90% of cases) are the most prevalent. Surgery is the mainstay of treatment in patients with DTC. The current recommendations are based not on prosp...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:10.5603/EP.a2019.0033

    authors: Czarniecka A,Woźniak G,Kropińska A,Jarząb B,Handkiewicz-Junak D

    更新日期:2019-01-01 00:00:00

  • Amiodarone-induced thyroid dysfunction in an iodine-replete area: epidemiological and clinical data.

    abstract:INTRODUCTION:The present study aims to evaluate the incidence, types, timing and risk factors in amiodarone (AMD)-induced thyroid dysfunction. MATERIAL AND METHODS:The study comprised 229 patients from an iodine-replete area (115 women, 114 men, mean age 63.8 ± 9.2 years), chronically treated with AMD. The cases were ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Zosin I,Balaş M

    更新日期:2012-01-01 00:00:00

  • Vascular and cardiac function in young adults with classical congenital adrenal hyperplasia.

    abstract:INTRODUCTION:Patients with classical congenital adrenal hyperplasia (CAH) have increased cardiovascular risk, but the vascular and cardiac function during longitudinal corticoids replacement therapy is not known thoroughly. MATERIAL AND METHODS:Cross-sectional study of 19 Caucasian adults with CAH (age 23.7 ± 3.8 year...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2017.0046

    authors: Wierzbicka-Chmiel J,Chmiel A,Rychlik S,Ogrodowczyk-Bobik M,Marek B,Kajdaniuk D

    更新日期:2017-01-01 00:00:00

  • Anaplastic thyroid carcinoma with rapid thyrotoxicosis - a case report and the literature review.

    abstract:INTRODUCTION:Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies and constitutes approximately 1.6-5% of the malignant neoplasms of the thyroid gland. ATC usually manifests itself with the local symptoms due to a rapidly enlarging thyroid mass, and as other thyroid cancers, has only seld...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:10.5603/EP.a2018.0010

    authors: Daroszewski J,Paczkowska K,Jawiarczyk-Przybyłowska A,Bolanowski M,Jeleń M

    更新日期:2018-01-01 00:00:00

  • Autonomous functioning thyroid nodule - a rare paediatric diagnosis.

    abstract::Not required for Clinical Vignette. ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2020.0071

    authors: Rey Y Formoso V,Salazar D,Fernandes S,Ferreira S,Estevinho N,Castro Correia C

    更新日期:2020-01-01 00:00:00

  • Thyroid hormones in the central nervous system (CNS) and their effect on neoplasm formation, particularly on the development and course of glioblastoma multiforme - research hypothesis.

    abstract::The present study is aimed to present the potential role of thyroid hormones (TH) in the pathogenesis of glioblastoma multiforme (GBM). In first part of this presentation the effect of general homeostasis of TH on GBM formation and course was shown. Then the evidence concerning present state of the knowledge about act...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:10.5603/EP.2015.0055

    authors: Nauman P

    更新日期:2015-01-01 00:00:00

  • Oncogenic osteomalacia should be considered in hypophosphatemia, bone pain and pathological fractures.

    abstract::The clinical manifestation of oncogenic osteomalacia includes bone pain, pathological fractures, general fatigue and muscle weakness. Such unspecific symptoms hinder the establishment of a proper diagnosis which very often requires long-lasting investigations with many diagnostic imaging methods. Here, we discuss di...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Kaniuka-Jakubowska S,Biernat W,Lewczuk A,Świątkowska-Stodulska R,Sworczak K

    更新日期:2012-01-01 00:00:00

  • [Comparison of CD15, galectin-3 and HBME-1 expression in follicular thyroid neoplasms].

    abstract:INTRODUCTION:Estimation of malignancy in thyroid follicular neoplasms is a common diagnostic problem, thus revealing of differences in expression of some antigens in both benign and malignant lesions seems to be essential. The aim of this study is to evaluate the immunohistochemical expression of CD15, galectin-3 and H...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Bogdańska M,Górnicka B,Ziarkiewicz-Wróblewska B,Koperski L,Morton M,Wasiutyński A

    更新日期:2006-07-01 00:00:00

  • Low serum levels of meteorin-like/subfatin: an indicator of diabetes mellitus and insulin resistance?

    abstract:INTRODUCTION:Meteorin-like (Metrnl), also known as subfatin, is a recently discovered adipokine with a favourable effect on insulin sensitivity. Studies have shown lower Metrnl levels in obese patients. However, data on its circulating levels in type 2 diabetes mellitus (T2DM) patients are contradictory. This study aim...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2020.0038

    authors: Onalan E,Cavlı C,Dogan Y,Onalan E,Gozel N,Buran I,Yakar B,Donder E

    更新日期:2020-01-01 00:00:00

  • Bone status in adolescents and young adults with type 1 diabetes: a 10-year longitudinal study.

    abstract:INTRODUCTION:This study presents a 10-year longitudinal assessment of bone status in adolescents and young adults with type 1 diabetes (T1D). MATERIAL AND METHODS:Thirty-two patients (12 female, aged 20.5 ± 3.93 years, T1D duration 13.9 ± 1.97 years) were studied using quantitative ultrasound (QUS) and dual-energy X-r...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2020.0080

    authors: Chobot A,Janota O,Bąk-Drabik K,Polanska J,Pluskiewicz W

    更新日期:2020-01-01 00:00:00

  • [Pharmacologic effect of excess iodine on type I thyroxine 5'-deiodinase activity in rat thyroid].

    abstract::Many mechanism may participate in the inhibition of thyroid function by excess of iodine. The present study was aimed at answering the question, whether the excess of iodine influences the activity of type I thyroxine 5'-deiodinase. To 40 female rats fed with standard diet a dose of 42 micrograms of iodine daily was a...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Bednarczuk T,Pietrzykowski A,Słoń M,Nauman A

    更新日期:1993-01-01 00:00:00

  • Chronic noise exposure and testosterone deficiency -- meta-analysis and meta-regression of experimental studies in rodents.

    abstract:INTRODUCTION:Chronic psychological distress can cause suppression of the hypothalamic-pituitary-testicular axis and thus lead to male hypogonadism, which is associated with psycho-social dysfunction, chronic diseases, and as a result, considerable economic costs. Conversely, noise is a prototypal environmental stressor...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,meta分析,评审

    doi:10.5603/EP.2015.0007

    authors: Dzhambov A,Dimitrova D

    更新日期:2015-01-01 00:00:00

  • Management of patients with secondary and tertiary hyperparathyroidism referred to surgical treatment.

    abstract:INTRODUCTION:Aim of the study was present personal observations connected with the management of patients referred to surgical treatment for secondary hyperparathyroidism (SHT) or tertiary hyperparathyroidism (THT), and to assess immediate results of such management. MATERIAL AND METHODS:A total of 175 patients aged 2...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Buła G,Koziołek H,Niemiec A,Gawrychowski J

    更新日期:2010-05-01 00:00:00

  • Thyroid hormones and obesity: a known but poorly understood relationship.

    abstract::Hormony tarczycy (thyroid hormones, TH) są zaangażowane w wiele różnych procesów biologicznych, wliczając rozwój układu nerwowego, regulację metabolizmu pośredniego oraz zużycie energii. Aktywnie uczestniczą w podstawowym zużyciu energii i termogenezie adaptacyjnej i z tego względu mogą mieć wpływ na masę ciała w prze...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:10.5603/EP.2018.0032

    authors: García-Solís P,García OP,Hernández-Puga G,Sánchez-Tusie AA,Sáenz-Luna CE,Hernández-Montiel HL,Solis-S JC

    更新日期:2018-01-01 00:00:00

  • The management of Cushing's disease - from investigation to treatment.

    abstract::Cushing's disease (CD) is caused by an adrenocorticotrophin (ACTH) secreting pituitary adenoma and it is the commonest cause of endogenous hypercortisolism. When high suspicion of Cushing's syndrome (CS) exists, recommended screening tests include the overnight dexamethasone suppression test, the low-dose dexamethason...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:

    authors: Juszczak A,Grossman A

    更新日期:2013-01-01 00:00:00

  • Cardiometabolic risk factors in young women with macroprolactinaemia.

    abstract:INTRODUCTION:The predominance of high-molecular-weight forms of prolactin in plasma is referred to as macroprolactinaemia. Unlike monomeric hyperprolactinaemia, no previous study has investigated cardiometabolic risk factors in subjects with elevated macroprolactin content. MATERIAL AND METHODS:We studied two age-, we...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2019.0013

    authors: Krysiak R,Marek B,Okopień B

    更新日期:2019-01-01 00:00:00

  • [Thyroid hormones and the cardiomyocytes].

    abstract::The authors present the current knowledge on the intracellular mechanisms of thyroid hormone action in the cardiomyocytes. Many of the clinical manifestations of thyroid diseases are due to the ability of thyroid hormone to alter cardiovascular hemodynamics. Triiodothyronine affects the hemodynamic state mainly by its...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:

    authors: Gatnar A,Marek B,Pakuła D,Kajdaniuk D,Kos-Kudła B,Borgiel-Marek H,Gnot R,Pakuła P,Pawłowska M

    更新日期:2006-03-01 00:00:00

  • Thyroid cancer post radioactive iodine treatment for hyperthyroidism - case series and review of the literature.

    abstract:INTRODUCTION:To assess the rate of thyroid cancer and mortality rate in a cohort of patients who received RAI¹³¹ treatment for hyperthyroidism and to report the index cases' characteristics and management MATERIAL AND METHODS: A cohort of 264 patients who received RAI¹³¹ treatment for different causes of thyrotoxicosis...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:10.5603/EP.a2017.0037

    authors: Al Eyadeh AA,Al-Sarihin K,Etewi S,Al-Omari A,Al-Asa'd RA,Haddad FH

    更新日期:2017-01-01 00:00:00

  • [Corticosteroids effect on angiogenesis in heart muscle].

    abstract::The process of angiogenesis in a heart muscle is a way of providing the ischaemic myocardium with oxygen and nutritive ingredients. This natural process called therapeutic angiogenesis has been tried in the treatment of patients with coronary artery disease mainly. It has been seen as a chance of an effective benefici...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:

    authors: Jośko J,Ratman K,Ratman RM

    更新日期:2007-09-01 00:00:00

  • Immunoglobulin G4 related thyroid disorders: Diagnostic challenges and clinical outcomes.

    abstract::Ig-G4 related disease (IgG4RD) is a heterogeneous disorder with multi-organ involvement recognised as a separate entity at the start of this century only. It is currently one of the hottest areas of clinical and translational research across specialties. Thyroid involvement in IgG4RD is rare, believed to occur in less...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:10.5603/EP.2016.0061

    authors: Dutta D,Ahuja A,Selvan C

    更新日期:2016-01-01 00:00:00

  • The safety and efficacy of biphasic insulin aspart 30 (BIAsp 30) in Iranians with type 2 diabetes: an open-label, non-randomised, multi-centre observational study--the Iran subgroup of the IMPROVE™ study.

    abstract:INTRODUCTION:To evaluate the clinical profile of BIAsp 30 (30% soluble insulin aspart, 70% protamine-crystallized insulin aspart) (NovoMix®)30) in type 2 diabetes patients in routine clinical practice in Iran. MATERIAL AND METHODS:IMPROVE™ was a 26-week, multinational, open-label, non-randomized study in patients with...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Esteghamati A,Rajabian R,Amini M,Bahrami A,Khamseh ME,Afkhami-Ardekani M,Rizi EP

    更新日期:2010-07-01 00:00:00

  • The clinical course of poorly differentiated thyroid carcinoma (insular carcinoma) - own observations.

    abstract:INTRODUCTION:Poorly differentiated thyroid carcinoma (PDTC, insular carcinoma) occurs rarely. It is described with more aggressive behaviour, poorer prognosis, and higher mortality than well differentiated thyroid carcinoma (WDTC). The aim of this study was to evaluate the clinical course of patients with PDTC, in addi...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Walczyk A,Kowalska A,Sygut J

    更新日期:2010-09-01 00:00:00

  • Patient satisfaction and preferences of lanreotide Autogel treatment in acromegaly.

    abstract:INTRODUCTION:Despite the known importance of somatostatin analogues (SSAs) in the treatment of acromegaly, patient satisfaction leading to preferences for specific SSAs have received little attention so far. MATERIAL AND METHODS:This open, prospective, observational, multicentre patient-reported outcome study included...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,多中心研究

    doi:10.5603/EP.2016.0066

    authors: Witek P,Mucha S,Ruchała M

    更新日期:2016-01-01 00:00:00

  • [The role of cholecystokinin octapeptide (CCK-8) in regulating thyrotropin secretion in rats. In vivo studies].

    abstract::The effect of cholecystokinin octapeptide (CCK-8) on basal and TRH-stimulated secretion of TSH was investigated in 67 male Sprague-Dawley rats. Blood for TSH determinations was sampled by cannulation of right heart auricle in urethane narcosis before and four times during 60 minutes following CCK-8 administration. It ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:

    authors: Krowicki ZK,Sadowska-Krowicka H

    更新日期:1989-01-01 00:00:00

  • Ten-year estimated risk of bone fracture in women with differentiated thyroid cancer under TSH-suppressive levothyroxine therapy.

    abstract:INTRODUCTION:After thyroidectomy and radioiodine therapy, patients with differentiated thyroid cancer (DTC) are indefinitely treated with levothyroxine (L-T4). Osteoporosis is a debated consequence of hypothyroxinaemia. The aim of this study was to evaluate bone mineral density (BMD) and fracture risk assessed by FRAX ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2016.0046

    authors: Vera L,Gay S,Campomenosi C,Paolino S,Pera G,Monti E,Mortara L,Seriolo B,Giusti M

    更新日期:2016-01-01 00:00:00

  • [Hyperprolactinemia: causes, diagnosis, and treatment].

    abstract::The basic data on hyperprolactinemia (i.e. an excess of PRL above a reference laboratory's upper limits), the most common endocrine disorder of the hypothalamic-pituitary axis are given in this review. The following issues are discussed: regulation of prolactin (Prl) secretion, definition of hyperprolactinemia, its et...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章,评审

    doi:

    authors: Karasek M,Pawlikowski M,Lewiński A

    更新日期:2006-11-01 00:00:00

  • An overview of biological research on hypoxia-inducible factors (HIFs).

    abstract::Hypoxia-inducible factors (HIFs), as a family of transcription factors involved in the cellular response to hypoxia, are key regulatory factors in the regulation mechanism of an organism's response to hypoxia. A large number of studies have shown that HIFs are closely related to the angiogenesis, erythropoiesis, cell ...

    journal_title:Endokrynologia Polska

    pub_type: 杂志文章

    doi:10.5603/EP.a2020.0064

    authors: Liu Z,Wu Z,Fan Y,Fang Y

    更新日期:2020-01-01 00:00:00