Abstract：
INTRODUCTION:This study presents a 10-year longitudinal assessment of bone status in adolescents and young adults with type 1 diabetes (T1D). MATERIAL AND METHODS:Thirty-two patients (12 female, aged 20.5 ± 3.93 years, T1D duration 13.9 ± 1.97 years) were studied using quantitative ultrasound (QUS) and dual-energy X-ray absorptiometry (DXA). Standard deviation scores (SDS) for these results were calculated. The following clinical parameters were analysed: sex, age, T1D duration, anthropometric parameters, daily insulin requirement (DIR), mean glycated haemoglobin (HbA1c) in the year preceding the examination, medication other than insulin, history of bone fractures, and comorbidities. RESULTS:The current and past (measured 10 years earlier) QUS results did not differ and showed a significant correlation (r = 0.55, p = 0.001). We found no relation of QUS results and anthropometric parameters or gender. DXA parameters did not correlate with the present QUS measurement. DXA and QUS results were independent of HbA1c, co-morbidities, or intake of additional medicaments. CONCLUSIONS:Bone status parameters of the examined patients with currently suboptimal glycaemic control were found to be lowered in comparison to a normative reference population, both at baseline and follow-up, although no further deterioration was observed during the 10-year follow-up period.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Chobot A,Janota O,Bąk-Drabik K,Polanska J,Pluskiewicz Wdoi
10.5603/EP.a2020.0080subject
Has Abstractpub_date
2020-01-01 00:00:00pages
532-538issue
6eissn
0423-104Xissn
2299-8306pii
VM/OJS/J/70441journal_volume
71pub_type
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journal_title：Endokrynologia Polska
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更新日期：2012-01-01 00:00:00
abstract：:The study was aimed at the assessment of frequency of occurrence of thyroid antimicrosomal and antithyreoglobuln autoantibodies in children with insulin-dependent diabetes and healthy control children. The occurrence of thyroid autoantibodies was analyzed with respect to the age and sex of children and the duration of...
journal_title：Endokrynologia Polska
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更新日期：1989-01-01 00:00:00
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journal_title：Endokrynologia Polska
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更新日期：2009-11-01 00:00:00
abstract：:According to the socio-sexological reports approximately 40-45% of women and up to 30% of males may suffer from different sexual dysfunctions. The prevalence of those disorders is gradually increasing with age. Multiply numbers of endocrinopathies may influence the human sexual life. In diabetic patients all phases of...
journal_title：Endokrynologia Polska
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更新日期：2005-11-01 00:00:00
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
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doi：
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journal_title：Endokrynologia Polska
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doi：
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
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doi：
更新日期：2012-01-01 00:00:00
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doi：
更新日期：2010-01-01 00:00:00
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