Abstract:
:We have recently observed an increased interest in gastro-entero-pancreatic neuroendocrine tumors (GEP NET). They are rare cancer types and therefore collaborative effort of specialists in various disciplines of medicine is necessary to work out the diagnostic and therapeutic guidelines. In this publication we present general guidelines of the Polish Network of Neuroendocrine Tumors for the management of patients with GEP NET, developed at the Round Table Conference which took place in Kliczków near Wrocław in November 2007. In the subsequent parts of this publication, we present the rules of diagnostic and therapeutic management of: - endocrine tumors of the stomach and duodenum (including gastrinoma); - pancreatic endocrine tumors; - neuroendocrine tumors of the small intestine and the appendix; - neuroendocrine tumors of the colon. We hope that the proposed guidelines by Polish and foreign experts representing various disciplines of medicine, including endocrinology, gastroenterology, surgery, oncology, nuclear medicine and pathomorphology, will become a useful tool in the diagnostics and treatment of these patients.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Kos-Kudła B,Bolanowski M,Handkiewicz-Junak D,Jarzab B,Królicki L,Krzakowski M,Kunikowska J,Nasierowska-Guttmejer A,Nowak A,Rydzewska G,Starzyńska T,Szawłowski A,oraz Pozostali Uczestnicy Konferencji Okragłego Stołu.subject
Has Abstractpub_date
2008-01-01 00:00:00pages
41-56issue
1eissn
0423-104Xissn
2299-8306journal_volume
59pub_type
杂志文章abstract::Endocrinological Out-Patients Clinic at Children's Hospital in Dziekanów Leśny takes care of the children from Mazovia region. Hormonal findings in children with simple goiter were analyzed in several groups of patients. In all those patients preferential T3-secretion and decreased T4 production was found. These findi...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:Secondary hyperparathyroidism (sHPT) is one of the most common abnormalities found in patients with chronic kidney disease (CKD). Measurement of serum PTH concentrations is crucial in diagnosis and treatment of sHPT. Different methods of serum PTH measurement may provide diverse results. This may have a si...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2015.0028
更新日期:2015-01-01 00:00:00
abstract::The paper presents actual data concerning osteoporotic fractures (definitions, causes, epidemiologic and clinical data, consequences, treatment) particulary data about the most common fractures (distal forearm, vertebral and proximal hip fractures). ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2009-11-01 00:00:00
abstract::Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are often used by athletes as doping agents. It is estimated that up to 25% of sportsmen using anabolic-androgenic steroids also take GH. Available data do not confirm the influence of GH or IGF-1 preparations on physical performance improvement. However, th...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2009-09-01 00:00:00
abstract:INTRODUCTION:Poorly differentiated thyroid carcinoma (PDTC, insular carcinoma) occurs rarely. It is described with more aggressive behaviour, poorer prognosis, and higher mortality than well differentiated thyroid carcinoma (WDTC). The aim of this study was to evaluate the clinical course of patients with PDTC, in addi...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::The survey carried out in May 1991 in the city of Białystok comprised 308 children of age between 8 and 14 years and 116 young adults. In each of the studied subjects the size of the thyroid was measured by ultrasonography and iodine concentration determined in a randomly voided sample of urine. Body weight and height...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:Despite considerable progress in knowledge, ischaemic stroke is still a disease that causes serious clinical problems. A role in its pathogenesis can be attributed to i.a. adipose tissue hormones. The aim of this paper is to assess the blood levels of selected adipocytokines in patients during the acute ph...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2019.0057
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Dysregulation of adipokine secretion and action is a characteristic feature of obesity and a key clinical feature of Cushing's syndrome (CS). We have investigated whether endogenous glucocorticoid excess influences adipose tissue-derived gene expression. MATERIAL AND METHODS:mRNA expression of adipokines;...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2018.0091
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:The present study aims to evaluate the incidence, types, timing and risk factors in amiodarone (AMD)-induced thyroid dysfunction. MATERIAL AND METHODS:The study comprised 229 patients from an iodine-replete area (115 women, 114 men, mean age 63.8 ± 9.2 years), chronically treated with AMD. The cases were ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Since the effect of pre-therapeutic scintigraphy on the outcome of DTC treatment is debated, we evaluated factors affecting the effectiveness of (131)I therapy with respect to the delay between diagnostic scintigraphy and the application of radioiodine. MATERIAL AND METHODS:In the studied group of 60 pati...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract:INTRODUCTION:This study presents a 10-year longitudinal assessment of bone status in adolescents and young adults with type 1 diabetes (T1D). MATERIAL AND METHODS:Thirty-two patients (12 female, aged 20.5 ± 3.93 years, T1D duration 13.9 ± 1.97 years) were studied using quantitative ultrasound (QUS) and dual-energy X-r...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0080
更新日期:2020-01-01 00:00:00
abstract::In our study we present chosen elements of microarray analysis of gene expression profile in papillary thyroid cancer. The study group included 16 papillary thyroid cancer tissues and 16 corresponding normal tissues. Samples were analyzed on high density oligonucleotide microarrays (GeneChip HG-U133A) which contain 22...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::The treatment of Graves' orbitopathy (GO) remains a diagnostic and therapeutic challenge for clinicians worldwide. The elimination of risk factors, such as encouraging smoking cessation and achieving euthyroidism, are the most important and usually sufficient treatment methods in most mild cases. A course of selenium ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.2014.0054
更新日期:2014-01-01 00:00:00
abstract::The concentrations of beta-endorphin, ACTH, insulin (IRI), glucagon (IRG), cortisol and growth hormone were determined by radioimmunoassay during oral glucose tolerance test (OGTT) performed in 13 obese patients with normal glucose tolerance and without arterial hypertension. The test was performed in random, before a...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Patients with hypogonadism are at increased risk of cardiac and metabolic diseases and osteoporosis. Vitamin D and Fibroblast growth factor-23 (FGF-23) play role in the regulation of bone mineral metabolism and endothelial functions. Low vitamin D levels are reported in hypogonadism, while there is no data...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2017.0009
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Despite the known importance of somatostatin analogues (SSAs) in the treatment of acromegaly, patient satisfaction leading to preferences for specific SSAs have received little attention so far. MATERIAL AND METHODS:This open, prospective, observational, multicentre patient-reported outcome study included...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,多中心研究
doi:10.5603/EP.2016.0066
更新日期:2016-01-01 00:00:00
abstract::In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Endocrine Society has recently published recommendations on the diagnosis and management of PA. Due to the fact that the cu...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Generally, squamous cell carcinoma carries a poor prognosis because of its tendency to local invasion and subsequent metastasis, which is mediated by multiple factors and angiogenesis. Hepatocyte growth factor (HGF) is a potent mitogen for epithelial cells and regulates cell proliferation and migration and...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract::A case of 55 years old woman with "hot" right lobe toxic thyroid nodule, presenting with paroxysmal atrial fibrillation, and therefore treated with 131I 666MBq (18 mCi) is described. After six years she became pyrexic and suffered of severe cough proxyisms. The fine needle biopsy of the above nodule showed the presenc...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Tumor induced osteomalacia (TIO) are extremely rare paraneoplastic syndrome with less than 300 reported cases. This report highlights the pitfalls and challenges in diagnosing and localizing TIO in patients with refractory and resistant osteomalacia. PATIENT AND METHODS:41- year gentleman with 4-year histor...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2018.0016
更新日期:2018-01-01 00:00:00
abstract::Numerous members of semaphorins have been widely clarified to be involved in the development of multiple cancers. However, the semaphorin 6B (SEMA6B) has not yet been extensively reported in cancers, especially in thyroid carcinoma. According to the public dataset from TCGA database, we found that the expression of SE...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0072
更新日期:2020-10-30 00:00:00
abstract:INTRODUCTION:Oxytocin might be used therapeutically as an ally to rescue osteopathy resulting from diabetes. However, the in vivo effects of oxytocin on marrow adipogenesis in diabetes remain unknown. In this longitudinal study, we aimed to investigate the protective ef-fects of oxytocin on diabetes-induced marrow adip...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2018.0040
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:To assess in a prospective study the course and the predictors of microalbuminuria in children and adolescents with type 1 diabetes. MATERIAL AND METHODS:438 children and adolescents who developed diabetes in the years 1985-2004 were followed for 9.2 ± 3.4 years from the diagnosis. Microalbuminuria was as...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2014.0012
更新日期:2014-01-01 00:00:00
abstract::Increased interest in vitamin D measurements in clinical studies has contributed to the development in recent years of several new immunochemical assays (manual and for automatic analyzers). New methods, including HPLC (high performance liquid chromatography), and LC-MS/MS (liquid chromatography coupled with tandem ma...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Patients with Addison's disease experience many somatic and psychic changes, which decrease their quality of life. The aim of the study was to evaluate the "psychological equipment" of these patients to cope with stress connected with this chronic disease and the challenge of constant treatment. MATERIAL ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Hypolipidaemic agents were found to affect plasma adipokine levels, but no previous study has investigated whether this effect is sex-dependent. MATERIAL AND METHODS:We retrospectively analysed 61 patients participating in our previous studies, who because of isolated hypercholesterolaemia were treated wi...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2015.0017
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies and constitutes approximately 1.6-5% of the malignant neoplasms of the thyroid gland. ATC usually manifests itself with the local symptoms due to a rapidly enlarging thyroid mass, and as other thyroid cancers, has only seld...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.a2018.0010
更新日期:2018-01-01 00:00:00
abstract::The present study is aimed to present the potential role of thyroid hormones (TH) in the pathogenesis of glioblastoma multiforme (GBM). In first part of this presentation the effect of general homeostasis of TH on GBM formation and course was shown. Then the evidence concerning present state of the knowledge about act...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.2015.0055
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Bone disorders observed commonly after haematopoietic stem cells transplantation (HSCT) can be caused by several factors,but their detailed pathomechanism is still not well known, especially in childhood.The aim of this study was to evaluate: IGF-I, RANKL-OPG system, IL-6, and IL1β levels and their associa...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/ep.2013.0001
更新日期:2013-01-01 00:00:00
abstract::Obesity and thyroid function are closely related. Thyroid hormones are involved in the regulation of metabolism, thermogenesis, food intake, and fat oxidation. In obese children the most frequent hormonal abnormalities are slight hyperthyrotropinaemia and moderate increases in total T3 and/or fT3 concentrations. Those...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.2017.0007
更新日期:2017-01-01 00:00:00