[Gene expression analysis by DNA microarray in papillary thyroid cancer].

abstract：INTRODUCTION:Thyroid dysgenesis (TD) is the main cause of congenital hypothyroidism (CH), affecting nearly 1 in 2000-3000 newborns worldwide, as the most common neonatal endocrine disorder. Paired box gene 8 (PAX8), expressed during all stages of thyroid follicular cell, plays a key role in thyroid morphogenesis by a c...

journal_title：Endokrynologia Polska

authors： Li M,Wang F,Wang X,Zang Y,Liu W,Wang F,Zhang L,Tang Q,Liu S,Zhao D

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Surgery remains the most effective treatment for primary hyperparathyroidism (PHPT). Minimally invasive radioguided parathyroidectomy (MIRP) is a common technique for detecting and excising abnormal parathyroid glands. The aim of this study was to compare injections of low-dose and high-dose (99m) Tc metho...

journal_title：Endokrynologia Polska

authors： Jangjoo A,Sadeghi R,Mousavi Z,Mohebbi M,Khaje M,Asadi M

更新日期：2017-01-01 00:00:00

abstract：:A case of 55 years old woman with "hot" right lobe toxic thyroid nodule, presenting with paroxysmal atrial fibrillation, and therefore treated with 131I 666MBq (18 mCi) is described. After six years she became pyrexic and suffered of severe cough proxyisms. The fine needle biopsy of the above nodule showed the presenc...

journal_title：Endokrynologia Polska

authors： Górowski T,Gabryelewicz MB,Jastrzebska H

更新日期：1992-01-01 00:00:00

abstract：:Endocrinological Out-Patients Clinic at Children's Hospital in Dziekanów Leśny takes care of the children from Mazovia region. Hormonal findings in children with simple goiter were analyzed in several groups of patients. In all those patients preferential T3-secretion and decreased T4 production was found. These findi...

journal_title：Endokrynologia Polska

authors： Krawczyńska H,Dytkowska E,Wielgus M,Andrzejewski A,Wójcik-Musiałek K,Chmura M,Parucka J,Zmorzyńska T

更新日期：1992-01-01 00:00:00

abstract：INTRODUCTION:The recent investigations point out the significant role of oxidative stress in the development of thyroid gland disease. The present study was designed to investigate the variation of oxidative stae in women with non-autoimmunological subclinical hyperthyroidism. MATERIAL AND METHODS:The study was conduc...

journal_title：Endokrynologia Polska

authors： Rybus-Kalinowska B,Zwirska-Korczala K,Kalinowski M,Kukla M,Birkner E,Jochem J

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:Dysregulation of adipokine secretion and action is a characteristic feature of obesity and a key clinical feature of Cushing's syndrome (CS). We have investigated whether endogenous glucocorticoid excess influences adipose tissue-derived gene expression. MATERIAL AND METHODS:mRNA expression of adipokines;...

journal_title：Endokrynologia Polska

authors： Denes J,Zsippai A,Kovacs L,Gorombey Z,Kovacs GL,Goth M,Igaz P,Hubina E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We evaluated the predictive value of IGF-1 against hGH in the treatment outcome. MATERIAL AND METHODS:A prospective study was undertaken of 47 patients (mean age 41.1 ± 12.9 years; 44 with macroadenoma and 3 with microadenoma), requiring treatment with octreotide LAR (SSLAR) following incomplete surgery. Co...

journal_title：Endokrynologia Polska

authors： Bałdys-Waligórska A,Krzentowska-Korek A,Gołkowski F,Sokołowski G,Hubalewska-Dydejczyk A

更新日期：2011-01-01 00:00:00

abstract：:Obesity and thyroid function are closely related. Thyroid hormones are involved in the regulation of metabolism, thermogenesis, food intake, and fat oxidation. In obese children the most frequent hormonal abnormalities are slight hyperthyrotropinaemia and moderate increases in total T3 and/or fT3 concentrations. Those...

journal_title：Endokrynologia Polska

authors： Witkowska-Sędek E,Kucharska A,Rumińska M,Pyrżak B

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:The clinical usefulness of baroreflex sensitivity (BRS) in the early detection of autonomic dysfunction in patients with diabetes is not well established. The aim of the study was the evaluation of BRS in subjects with type 1 diabetes with and without cardiovascular autonomic neuropathy (CAN). MATERIAL AN...

journal_title：Endokrynologia Polska

authors： Kamińska A,Tafil-Klawe M,Smietanowski M,Bronisz A,Ruprecht Z,Klawe J,Junik R

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:Patients with hypogonadism are at increased risk of cardiac and metabolic diseases and osteoporosis. Vitamin D and Fibroblast growth factor-23 (FGF-23) play role in the regulation of bone mineral metabolism and endothelial functions. Low vitamin D levels are reported in hypogonadism, while there is no data...

journal_title：Endokrynologia Polska

authors： Haymana C,Sonmez A,Aydogdu A,Tapan S,Basaran Y,Meric C,Baskoy K,Taslipinar A,Yilmaz MI,Azal O

更新日期：2017-01-01 00:00:00

abstract：:Thyroid cancer in children is rare and accounts for 1-3% of all malignant tumours. Differentiated thyroid cancers (DTC) and particularly papillary thyroid carcinoma (PTC) (90% of cases) are the most prevalent. Surgery is the mainstay of treatment in patients with DTC. The current recommendations are based not on prosp...

journal_title：Endokrynologia Polska

authors： Czarniecka A,Woźniak G,Kropińska A,Jarząb B,Handkiewicz-Junak D

更新日期：2019-01-01 00:00:00

abstract：:The present study is aimed to present the potential role of thyroid hormones (TH) in the pathogenesis of glioblastoma multiforme (GBM). In first part of this presentation the effect of general homeostasis of TH on GBM formation and course was shown. Then the evidence concerning present state of the knowledge about act...

journal_title：Endokrynologia Polska

authors： Nauman P

更新日期：2015-01-01 00:00:00

abstract：:Hormony tarczycy (thyroid hormones, TH) są zaangażowane w wiele różnych procesów biologicznych, wliczając rozwój układu nerwowego, regulację metabolizmu pośredniego oraz zużycie energii. Aktywnie uczestniczą w podstawowym zużyciu energii i termogenezie adaptacyjnej i z tego względu mogą mieć wpływ na masę ciała w prze...

journal_title：Endokrynologia Polska

authors： García-Solís P,García OP,Hernández-Puga G,Sánchez-Tusie AA,Sáenz-Luna CE,Hernández-Montiel HL,Solis-S JC

更新日期：2018-01-01 00:00:00

abstract：:Numerous members of semaphorins have been widely clarified to be involved in the development of multiple cancers. However, the semaphorin 6B (SEMA6B) has not yet been extensively reported in cancers, especially in thyroid carcinoma. According to the public dataset from TCGA database, we found that the expression of SE...

journal_title：Endokrynologia Polska

authors： Lv XJ,Chen X,Wang Y,Yu S,Pang L,Huang C

更新日期：2020-10-30 00:00:00

abstract：INTRODUCTION:Patients with Addison's disease experience many somatic and psychic changes, which decrease their quality of life. The aim of the study was to evaluate the "psychological equipment" of these patients to cope with stress connected with this chronic disease and the challenge of constant treatment. MATERIAL ...

journal_title：Endokrynologia Polska

authors： Warmuz-Stangierska I,Baszko-Błaszyk D,Sowiński J

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Fine needle aspiration biopsy (FNAB) of the thyroid nodules generally allows to make the diagnosis and to choose the proper clinical management. In about 10% of cases cytopathologic features do not differentiate unequivocally benign and malignant lesions. In these cases the cytopathologic diagnosis of foll...

journal_title：Endokrynologia Polska

authors： Ponikiewska D,Szcześniak-Kłusek B,Stobiecka E,Jaworska M,Lange D

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Patients with classical congenital adrenal hyperplasia (CAH) have increased cardiovascular risk, but the vascular and cardiac function during longitudinal corticoids replacement therapy is not known thoroughly. MATERIAL AND METHODS:Cross-sectional study of 19 Caucasian adults with CAH (age 23.7 ± 3.8 year...

journal_title：Endokrynologia Polska

authors： Wierzbicka-Chmiel J,Chmiel A,Rychlik S,Ogrodowczyk-Bobik M,Marek B,Kajdaniuk D

更新日期：2017-01-01 00:00:00

abstract：:Renalase is a recently identified flavoprotein oxidase, secreted mainly by the kidneys, which takes part in the degradation of catecholamines. The catecholamine inactivating effect results in the modulation of the sympathetic system tension and, consequently, in a decrease of blood pressure, myocardial contractility, ...

journal_title：Endokrynologia Polska

authors： Czubilińska-Łada J,Gliwińska A,Badeński A,Szczepańska M

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:An increased risk of mortality in patients with uncontrolled acromegaly has been reported in several studies. We aimed to assess the impact of co-morbidities on the survival of patients with acromegaly after long-term treatment and follow-up. MATERIAL AND METHODS:A retrospective analysis was performed for...

journal_title：Endokrynologia Polska

authors： Wen-Ko C,Szu-Tah C,Feng-Hsuan L,Chen-Nen C,Ming-Hsu W,Jen-Der L

更新日期：2016-01-01 00:00:00

abstract：:Increased interest in vitamin D measurements in clinical studies has contributed to the development in recent years of several new immunochemical assays (manual and for automatic analyzers). New methods, including HPLC (high performance liquid chromatography), and LC-MS/MS (liquid chromatography coupled with tandem ma...

journal_title：Endokrynologia Polska

authors： Bartoszewicz Z,Kondracka A,Jaźwiec R,Popow M,Dadlez M,Bednarczuk T

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Fine needle aspiration biopsy (FNAB) is the main examination in diagnostics of thyroid nodules. Yet, it does not allow the differentiation of follicular lesions (FL). A new classification of thyroid biopsy results (newC) might improve pre-operative diagnostics mainly due to the introduction of a new subcat...

journal_title：Endokrynologia Polska

authors： Woźniak-Oseła E,Popowicz B,Sporny S,Klencki M,Słowińska-Klencka D

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The potential effect of adipokines on the development of AF is yet to be established. The aim of this study was to investigate the association of baseline serum adipokines with 1) the presence of AF at baseline and 2) future risk of AF development. MATERIAL AND METHODS:The current study is a sub-analysis ...

journal_title：Endokrynologia Polska

authors： Peller M,Kapłon-Cieślicka A,Rosiak M,Tymińska A,Ozierański K,Eyileten C,Kondracka A,Mirowska-Guzel D,Opolski G,Postuła M,Filipiak KJ

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Surgeries that spare the adrenal cortex during adrenalectomy have profound justification. Indications for this type of surgery are fairly strict, and more than 30 years of observations continuously verify the results of the procedure. MATERIAL AND METHODS:Of a total of 650 adrenalectomies, 22 (3.4%) were ...

journal_title：Endokrynologia Polska

authors： Toutounchi S,Pogorzelski R,Wołoszko T,Krajewska E,Celejewski K,Legocka M,Jakuczun W,Gałązka Z

更新日期：2020-01-01 00:00:00

abstract：:Epidemiological foundation included: aim of studies, knowledge about epidemiology of thyroid disorders in Poland, evaluation of radioiodine dose accumulated in thyroids of inhabitants of different age living in different par of Poland, information about relative diet iodine deficiency in different parts of Poland and ...

journal_title：Endokrynologia Polska

authors： Nauman J,Roszkowska H

更新日期：1991-01-01 00:00:00

abstract：:Elevated levels of serum glucose have deleterious effects on the walls of blood vessels, leading to microangiopathy. Such a destructive process involves also pulmonary circulation, where it is referred to as diabetic pulmonary microangiopathy. This hypothesis has been confirmed in histopathologic examinations of pulmo...

journal_title：Endokrynologia Polska

authors： Kuziemski K,Specjalski K,Jassem E

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the number of women who take multivitamin formulations containing iodine. MATERIAL AND METHODS:A 34-question questionnaire was given to 500 women during their puerperal stay in two obstetrics/gynaecology wards in Krakow. RESULTS:295 pregnant women (59%) took iodine-con...

journal_title：Endokrynologia Polska

authors： Milewicz T,Czyżewicz M,Stochmal E,Galicka-Latała D,Hubalewska-Dydejczyk A,Krzysiek J

更新日期：2011-01-01 00:00:00

abstract：:Osteoporosis is a chronic disease of the osseous system characterised by decreased strength of bone tissue, which in turn leads to increased fracture risk. It has been demonstrated that osteoporosis affects more than 30% of women after the menopause (WHO, 1994). However, the disease is also observed in men. The primar...

journal_title：Endokrynologia Polska

authors： Sewerynek E,Stuss M

更新日期：2011-01-01 00:00:00

abstract：:Questionnaire, clinical, ultrasonographic and biochemical studies (determination of urinary iodine concentration) have been carried out in 1686 children of age between 7 and 13 years living in the Lublin Upland region. The presence of goiter was found in 368 children (21.8%). A gradual increase in the incidence of goi...

journal_title：Endokrynologia Polska

authors： Szewczyk L,Beń-Skowronek I,Jaklińska T,Lozowski C

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:Childhood obesity has been associated with the development of insulin resistance, potentially leading to several metabolic disorders. Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin sensitivity. The purpose of this study was to examine the relationship between...

journal_title：Endokrynologia Polska

authors： Garanty-Bogacka B,Syrenicz M,Rać M,Krupa B,Czaja-Bulsa G,Walczak M,Sowińska-Przepiera E,Syrenicz A

更新日期：2013-01-01 00:00:00

abstract：:The genetic risk of differentiated thyroid cancer (DTC) probably consists of multiple low-penetrance, single-nucleotide polymorphisms (SNP). Such markers are difficult to uncover by linkage analysis but can be revealed by association studies. Genome-wide association studies (GWASs) have uncovered 31 SNPs associated wi...

journal_title：Endokrynologia Polska

authors： Jendrzejewski JP,Sworczak K,Comiskey DF,de la Chapelle A

更新日期：2019-01-01 00:00:00