Abstract:
:Thyroid cancer in children is rare and accounts for 1-3% of all malignant tumours. Differentiated thyroid cancers (DTC) and particularly papillary thyroid carcinoma (PTC) (90% of cases) are the most prevalent. Surgery is the mainstay of treatment in patients with DTC. The current recommendations are based not on prospective randomised clinical trials, but on retrospective trials and expert opinions. Therefore, it is not easy to choose the optimal therapeutic strategy to obtain the best treatment and to avoid serious complications and adverse events. In children and adolescents, the clinical presentation, course, and prognosis are different from those seen in adults. Children are generally at low risk of death but at higher risk of long-term harm due to overly aggressive treatment. Therefore, optimisation of the therapeutic strategy is particularly important. The present paper provides a summary of the current guidelines on surgical management in thyroid tumours and DTC in children and adolescents.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Czarniecka A,Woźniak G,Kropińska A,Jarząb B,Handkiewicz-Junak Ddoi
10.5603/EP.a2019.0033subject
Has Abstractpub_date
2019-01-01 00:00:00pages
357-366issue
4eissn
0423-104Xissn
2299-8306pii
VM/OJS/J/61914journal_volume
70pub_type
杂志文章,评审abstract::Renalase is a recently identified flavoprotein oxidase, secreted mainly by the kidneys, which takes part in the degradation of catecholamines. The catecholamine inactivating effect results in the modulation of the sympathetic system tension and, consequently, in a decrease of blood pressure, myocardial contractility, ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0033
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:
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journal_title:Endokrynologia Polska
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