Abstract：
INTRODUCTION:To assess the rate of thyroid cancer and mortality rate in a cohort of patients who received RAI¹³¹ treatment for hyperthyroidism and to report the index cases' characteristics and management MATERIAL AND METHODS: A cohort of 264 patients who received RAI¹³¹ treatment for different causes of thyrotoxicosis were followed up over a period of 18 years (1996-2014) by physical exam, radiological evaluation and serial thyroid function tests. RESULTS:During the follow up period, three cases of thyroid cancer were identified. The prevalence of thyroid cancer was 1.136% of cases who received RAI¹³¹. The relative risk was 378.79 (95% CI: 76.8 < RR < 1868.23). The P value was < 0.0000004 and the SMR is 1.99/1000. CONCLUSIONS:The prevalence of thyroid cancer was 1.136% in the cohort of patients treated with RAI¹³¹. Despite the fact that no direct cause-effect relationship between RAI and thyroid cancer could be established, these cases highlights the importance of life-long surveillance of patients who receive RAI¹³¹.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Al Eyadeh AA,Al-Sarihin K,Etewi S,Al-Omari A,Al-Asa'd RA,Haddad FHdoi
10.5603/EP.a2017.0037subject
Has Abstractpub_date
2017-01-01 00:00:00pages
561-566issue
5eissn
0423-104Xissn
2299-8306pii
VM/OJS/J/47868journal_volume
68pub_type
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