Latent Autoimmune Diabetes in Adults: A Review on Clinical Implications and Management.

abstract：BACKGROUND:We investigated whether an intensive individualized reinforcement education program could influence the prevention of hypoglycemic events in patients with type 2 diabetes. METHODS:From March 2013 to September 2013, patients aged 35 to 75 years with type 2 diabetes who had not previously participated in diab...

journal_title：Diabetes & metabolism journal

authors： Yong YM,Shin KM,Lee KM,Cho JY,Ko SH,Yoon MH,Kim TW,Jeong JH,Park YM,Ko SH,Ahn YB

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Although many anti-diabetic drugs have been used to control hyperglycemia for decades, the efficacy of commonly-used oral glucose-lowering agents in Korean type 2 diabetic patients has yet to be clearly demonstrated. METHODS:We evaluated the efficacy of glimepiride, metformin, and rosiglitazone as initial t...

journal_title：Diabetes & metabolism journal

authors： Yoon KH,Shin JA,Kwon HS,Lee SH,Min KW,Ahn YB,Yoo SJ,Ahn KJ,Park SW,Lee KW,Sung YA,Park TS,Kim MS,Kim YK,Nam MS,Kim HS,Park IeB,Park JS,Woo JT,Son HY

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Women with one abnormal value (OAV) in a 100 g oral glucose tolerance test (OGTT) during pregnancy are reported to have an increased risk of adverse pregnancy outcomes. However, there is limited data about whether women with OAV will progress to gestational diabetes mellitus (GDM) when the OGTT is repeated. ...

journal_title：Diabetes & metabolism journal

authors： Kang S,Kim MH,Kim MY,Hong JS,Kwak SH,Choi SH,Lim S,Park KS,Jang HC

更新日期：2019-10-01 00:00:00

abstract：:Diabetes is a leading cause of end-stage renal disease. Therefore, prevention of renal dysfunction is an important treatment goal in the management of diabetes. The data of landmark cardiovascular outcome trials of sodium-glucose cotransporter-2 (SGLT2) inhibitor showed profound reno-protective effects. The Korean Dia...

journal_title：Diabetes & metabolism journal

authors： Oh TJ,Moon JY,Hur KY,Ko SH,Kim HJ,Kim T,Lee DW,Moon MK,Committee of Clinical Practice Guideline, Korean Diabetes Association.,Committee of the Cooperative Studies, Korean Society of Nephrology.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The objective of this systematic review and meta-analysis was to determine the effects of omega-3 supplementation on adipocytokine levels in adult prediabetic and diabetic individuals. METHODS:We searched PubMed, Medline, EMBASE, Scopus, Web of Science, Google Scholar, Cochrane Trial Register, World Health ...

journal_title：Diabetes & metabolism journal

authors： Becic T,Studenik C

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The aim of this study is to investigate the cardio-metabolic parameters and surrogate markers of insulin resistance in a discordant group of type 2 diabetes (T2DM) subjects who satisfy the Adults Treatment Panel (ATP) III criteria, but not the International Diabetes Federation (IDF) criteria, for metabolic s...

journal_title：Diabetes & metabolism journal

authors： Lee SR,Han Y,Kim JW,Park JY,Kim JM,Suh S,Park MK,Lee HJ,Kim DK

更新日期：2012-10-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and NAFLD severity (incl...

journal_title：Diabetes & metabolism journal

authors： Lee YH,Cho Y,Lee BW,Park CY,Lee DH,Cha BS,Rhee EJ

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Diabetes self-management education and reinforcement are important for effective management of the disease. We investigated the effectiveness of interactive small-group education on glycemic, blood pressure, and lipid levels. METHODS:For this study, 207 type 2 diabetes patients with suboptimal glycemic cont...

journal_title：Diabetes & metabolism journal

authors： Choi MJ,Yoo SH,Kim KR,Bae YM,Ahn SH,Kim SS,Min SA,Choi JS,Lee SE,Moon YJ,Rhee EJ,Park CY,Lee WY,Oh KW,Park SW,Kim SW

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:We investigated whether patients' perceived glycemic control and self-reported diabetes self-care correlated with their actual glycemic control. METHODS:A survey was administered among patients with diabetes mellitus at an outpatient clinic with structured self-report questionnaires regarding perceived glyc...

journal_title：Diabetes & metabolism journal

authors： Ohn JH,Lee JH,Hong ES,Koo BK,Kim SW,Yi KH,Moon MK

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:This study investigated the rate of relapse of dyslipidemia and the factors which could predict relapse following a short-term statin discontinuation after achieving a target low density lipoprotein cholesterol (LDL-C) level in type 2 diabetic patients without cardiovascular disease (CVD). METHODS:Ninety-ni...

journal_title：Diabetes & metabolism journal

authors： Lee SH,Kwon HS,Park YM,Ko SH,Choi YH,Yoon KH,Ahn YB

更新日期：2014-02-01 00:00:00

abstract：:Knowledge of the epidemiologic characteristics of end-stage kidney disease (ESKD) patients is essential. The trends in the prevalence, incidence, and mortality rates of ESKD were analyzed retrospectively using the Korean National Health Insurance ServiceNational Sample Cohort database between 2006 and 2015. From 2006 ...

journal_title：Diabetes & metabolism journal

authors： Lee MJ,Ha KH,Kim DJ,Park I

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:We investigated the therapeutic effects of resistance training on Zucker rats before and after the onset of diabetes to understand the importance of the timing of exercise intervention. We assessed whether 8 weeks of resistance training ameliorated impaired glucose tolerance and altered muscle fiber type com...

journal_title：Diabetes & metabolism journal

authors： Kim JY,Choi MJ,So B,Kim HJ,Seong JK,Song W

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:In order to overcome the limitations of body mass index (BMI) and waist circumference (WC), the z-score of the log-transformed A Body Shape Index (LBSIZ) has recently been introduced. In this study, we analyzed the relationship between the LBSIZ and cardiovascular disease (CVD) in a Korean representative sam...

journal_title：Diabetes & metabolism journal

authors： Chung W,Park JH,Chung HS,Yu JM,Moon S,Kim DS

更新日期：2019-10-01 00:00:00

abstract：:In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various ...

journal_title：Diabetes & metabolism journal

authors： Rhee SY,Kim YS

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Despite the confluence of multiple cardiovascular risk factors, subclinical atherosclerotic damage and cardiovascular events remain extremely rare in adults with Down syndrome (DS). We aim to determine the prevalence of obesity and metabolic disorders in an adult cohort with DS and to compare our findings wi...

journal_title：Diabetes & metabolism journal

authors： Real de Asua D,Parra P,Costa R,Moldenhauer F,Suarez C

更新日期：2014-12-01 00:00:00

abstract：:A growing body of evidence suggests that hyperglycemia-induced oxidative stress plays an important role in diabetic complications, especially β-cell dysfunction and failure. Under physiological conditions, reactive oxygen species serve as second messengers that facilitate signal transduction and gene expression in pan...

journal_title：Diabetes & metabolism journal

authors： Karunakaran U,Park KG

更新日期：2013-04-01 00:00:00

abstract：:The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient utilization of fatty acid and glucose, which is controlled by the PDC. The PDC converts pyruvate...

journal_title：Diabetes & metabolism journal

authors： Lee IK

更新日期：2014-06-01 00:00:00

abstract：:As the number of individuals with non-alcoholic fatty liver disease (NAFLD) has increased, the influence of NAFLD on other metabolic diseases has been highlighted. Accumulating epidemiologic evidence indicates that NAFLD not only affects the liver but also increases the risk of extra-hepatic diseases such as type 2 di...

journal_title：Diabetes & metabolism journal

authors： Han E,Lee YH

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was an in vitro investigation of the effect of high glucose concentration on adipogenesis, as prolonged hyperglycemia alters adipocyte differentiation. METHODS:3T3-L1 preadipocytes differentiated in the presence of varying concentrations of glucose (25, 45, 65, 85, and 105 mM) were ass...

journal_title：Diabetes & metabolism journal

authors： Shilpa K,Dinesh T,Lakshmi BS

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the influences of visceral adiposity on cardiovascular autonomic neuropathy (CAN) in patients with type 2 diabetes mellitus. METHODS:Two hundred eleven patients with type 2 diabetes participated in this study. Anthropometric and metabolic parameters were measured, an...

journal_title：Diabetes & metabolism journal

authors： Jang EH,Kim NY,Park YM,Kim MK,Baek KH,Song KH,Lee KW,Kwon HS

更新日期：2012-08-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic steatohepatitis (NASH). A combination of environmental factors, h...

journal_title：Diabetes & metabolism journal

authors： Povero D,Feldstein AE

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:A 64-slice multidetector computed tomography (MDCT) is well known to be a useful noninvasive form of angiography for the general population, but not for certain patients with diabetes. The aim of this study was to investigate the diagnostic accuracy and usefulness of 64-slice MDCT coronary angiography for de...

journal_title：Diabetes & metabolism journal

authors： Moon JS,Yoon JS,Won KC,Cho IH,Lee HW

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:The prevalence and incidence of type 1 diabetes mellitus (T1DM) in all age groups and the prevalence of metabolic syndrome in patients with T1DM in Korea were estimated. METHODS:The incidence and prevalence of T1DM between 2007 and 2013 were calculated using the Korean National Health Insurance Service (NHI...

journal_title：Diabetes & metabolism journal

authors： Lee YB,Han K,Kim B,Jin SM,Lee SE,Jun JE,Ahn J,Kim G,Kim JH

更新日期：2019-02-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine [5-HT]) is a monoamine that has various functions in both neuronal and non-neuronal systems. In the central nervous system, 5-HT regulates mood and feeding behaviors as a neurotransmitter. Thus, there have been many trials aimed at increasing the activity of 5-HT in the central nervous s...

journal_title：Diabetes & metabolism journal

authors： Oh CM,Park S,Kim H

更新日期：2016-04-01 00:00:00

abstract：:Although glucose-lowering treatment shows some risk lowering effects in cardiovascular diseases, risks of macrovascular and microvascular complications have still remained, and development of new therapeutic strategies is needed. Recent data have shown that peroxisome proliferator activated receptor-α (PPAR-α) plays a...

journal_title：Diabetes & metabolism journal

authors： Seok H,Cha BS

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) is associated with an increased risk for dementia. The effects of hypoglycemia on dementia are controversial. Thus, we evaluated whether hypoglycemia increases the risk for dementia in senior patients with T2DM. METHODS:We used the Korean National Health Insurance Service Sen...

journal_title：Diabetes & metabolism journal

authors： Kim YG,Park DG,Moon SY,Jeon JY,Kim HJ,Kim DJ,Lee KW,Han SJ

更新日期：2020-02-01 00:00:00

abstract：:Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both are difficult to enforce. There has been renewed interest in exploiting pathways such as uncoupling protein 1 (UCP1)-me...

journal_title：Diabetes & metabolism journal

authors： Periasamy M,Herrera JL,Reis FCG

更新日期：2017-10-01 00:00:00

abstract：:Cyclic adenosine monophosphate (cAMP) signaling is critical for regulating metabolic homeostasis in mammals. In particular, transcriptional regulation by cAMP response element-binding protein (CREB) and its coactivator, CREB-regulated transcription coactivator (CRTC), is essential for controlling the expression of cri...

journal_title：Diabetes & metabolism journal

authors： Han HS,Kwon Y,Koo SH

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Chronic exposure to elevated levels of free fatty acids contributes to pancreatic β-cell dysfunction. Although it is well known that metformin induces cellular energy depletion and a concomitant activation of AMP-activated protein kinase (AMPK) through inhibition of the respiratory chain, previous studies ha...

journal_title：Diabetes & metabolism journal

authors： Kim HI,Lee JS,Kwak BK,Hwang WM,Kim MJ,Kim YB,Chung SS,Park KS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Voglibose, an α-glucosidase inhibitor, inhibits breakdown of complex carbohydrates into simple sugar units in intestine. Studies showed that voglibose metabolism in the liver might be negligible due to its poor intestinal absorption. Numerous microorganisms live in intestine and have several roles in metabol...

journal_title：Diabetes & metabolism journal

authors： Nepal MR,Kang MJ,Kim GH,Cha DH,Kim JH,Jeong TC

更新日期：2020-12-01 00:00:00