Refocusing Peroxisome Proliferator Activated Receptor-α: A New Insight for Therapeutic Roles in Diabetes.

abstract：BACKGROUND:To investigate the clinical results of sitagliptin (SITA) and the characteristics of the treatment failure group or of low responders to SITA. METHODS:A retrospective study of type 2 diabetic patients reviewed 99 cases, including 12 treatment failure cases, who stopped SITA because of worsening patients' co...

journal_title：Diabetes & metabolism journal

authors： Kim WJ,Park CY,Jeong EH,Seo JY,Seol JS,Park SE,Rhee EJ,Lee WY,Oh KW,Park SW,Kim SW

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Although many anti-diabetic drugs have been used to control hyperglycemia for decades, the efficacy of commonly-used oral glucose-lowering agents in Korean type 2 diabetic patients has yet to be clearly demonstrated. METHODS:We evaluated the efficacy of glimepiride, metformin, and rosiglitazone as initial t...

journal_title：Diabetes & metabolism journal

authors： Yoon KH,Shin JA,Kwon HS,Lee SH,Min KW,Ahn YB,Yoo SJ,Ahn KJ,Park SW,Lee KW,Sung YA,Park TS,Kim MS,Kim YK,Nam MS,Kim HS,Park IeB,Park JS,Woo JT,Son HY

更新日期：2011-02-01 00:00:00

abstract：:There are many studies on the prevalence, clinical characteristics, and economic burden of diabetes across the past four decades in Korea. Nonetheless, there is a dearth of nationwide study regarding diabetes encompassing all age group. Eight years ago, the Committee on the Epidemiology of Diabetes Mellitus of Korean ...

journal_title：Diabetes & metabolism journal

authors： Task Force Team for Basic Statistical Study of Korean Diabetes Mellitus of Korean Diabetes Association.,Park IeB,Kim J,Kim DJ,Chung CH,Oh JY,Park SW,Lee J,Choi KM,Min KW,Park JH,Son HS,Ahn CW,Kim H,Lee S,Lee IB,Choi I,B

更新日期：2013-08-01 00:00:00

abstract：:This corrects the article on p. 218 in vol. 39, PMID: 26124992. ...

journal_title：Diabetes & metabolism journal

authors： Natasha K,Hussain A,Azad Khan AK,Bhowmik B

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Some patients admitted to hospitals for glycemic control experience hypoglycemia despite regular meals and despite adhering to standard blood glucose control protocols. Different factors can have a negative impact on blood glucose control and prognosis after discharge. This study investigated risk factors fo...

journal_title：Diabetes & metabolism journal

authors： Lee J,Kim TM,Kim H,Lee SH,Cho JH,Lee H,Yim HW,Yoon KH,Kim HS

更新日期：2020-08-01 00:00:00

abstract：:Genome wide association analyses have revealed large numbers of common variants influencing predisposition to type 2 diabetes and related phenotypes. These studies have predominantly featured European populations, but are now being extended to samples from a wider range of ethnic groups. The transethnic analysis of as...

journal_title：Diabetes & metabolism journal

authors： McCarthy MI

更新日期：2011-04-01 00:00:00

abstract：:The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient utilization of fatty acid and glucose, which is controlled by the PDC. The PDC converts pyruvate...

journal_title：Diabetes & metabolism journal

authors： Lee IK

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:A latent cytomegalovirus (CMV) cause chronic inflammation through undesirable inflation of cell-mediated immune response. CMV immunoglobulin G has been associated with cardiovascular disease and type 1 diabetes mellitus. We evaluated impact of CMV diseases on new-onset type 2 diabetes mellitus (T2DM). METHO...

journal_title：Diabetes & metabolism journal

authors： Yoo SG,Han KD,Lee KH,La Y,Kwon DE,Han SH

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Despite the confluence of multiple cardiovascular risk factors, subclinical atherosclerotic damage and cardiovascular events remain extremely rare in adults with Down syndrome (DS). We aim to determine the prevalence of obesity and metabolic disorders in an adult cohort with DS and to compare our findings wi...

journal_title：Diabetes & metabolism journal

authors： Real de Asua D,Parra P,Costa R,Moldenhauer F,Suarez C

更新日期：2014-12-01 00:00:00

abstract：:In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various ...

journal_title：Diabetes & metabolism journal

authors： Rhee SY,Kim YS

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The prevalence and incidence of type 1 diabetes mellitus (T1DM) in all age groups and the prevalence of metabolic syndrome in patients with T1DM in Korea were estimated. METHODS:The incidence and prevalence of T1DM between 2007 and 2013 were calculated using the Korean National Health Insurance Service (NHI...

journal_title：Diabetes & metabolism journal

authors： Lee YB,Han K,Kim B,Jin SM,Lee SE,Jun JE,Ahn J,Kim G,Kim JH

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The second derivative of the finger photoplethysmogram (SDPTG) is an indicator of arterial stiffness. The present study was conducted to clarify the factor structure of indices of the SDPTG in combination with components of the metabolic syndrome (MetS), to elucidate the significance of the SDPTG among vario...

journal_title：Diabetes & metabolism journal

authors： Kawada T,Otsuka T

更新日期：2013-02-01 00:00:00

abstract：:Care of the elderly population with diabetes may not be restricted to the management of hyperglycemia, associated risk factors, and specific diabetic complications. An integrated approach should also include the assessment and management of gerontological problems. Both diabetes mellitus and aging interact toward the ...

journal_title：Diabetes & metabolism journal

authors： Yoo HJ

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Rebaudioside A and erythritol are nonnutritive sweeteners. There have been several studies of their glycemic effects, but the outcomes remain controversial. The purpose of this study was to evaluate the glycemic effects of rebaudioside A and erythritol as a sweetener in people with glucose intolerance. METH...

journal_title：Diabetes & metabolism journal

authors： Shin DH,Lee JH,Kang MS,Kim TH,Jeong SJ,Kim CH,Kim SS,Kim IJ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is a chronic disease and one of the main causes of mortality in developing countries. The main objective of treating all chronic diseases, of course, is to improve well-being and attain a satisfactory quality of life (QOL). The major goal of this study is comparison of attitude toward QOL i...

journal_title：Diabetes & metabolism journal

authors： Hashemi Hefz Abad F,Shabany Hamedan M

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:A 64-slice multidetector computed tomography (MDCT) is well known to be a useful noninvasive form of angiography for the general population, but not for certain patients with diabetes. The aim of this study was to investigate the diagnostic accuracy and usefulness of 64-slice MDCT coronary angiography for de...

journal_title：Diabetes & metabolism journal

authors： Moon JS,Yoon JS,Won KC,Cho IH,Lee HW

更新日期：2013-02-01 00:00:00

abstract：:Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both are difficult to enforce. There has been renewed interest in exploiting pathways such as uncoupling protein 1 (UCP1)-me...

journal_title：Diabetes & metabolism journal

authors： Periasamy M,Herrera JL,Reis FCG

更新日期：2017-10-01 00:00:00

abstract：:Diabetes is a leading cause of end-stage renal disease. Therefore, prevention of renal dysfunction is an important treatment goal in the management of diabetes. The data of landmark cardiovascular outcome trials of sodium-glucose cotransporter-2 (SGLT2) inhibitor showed profound reno-protective effects. The Korean Dia...

journal_title：Diabetes & metabolism journal

authors： Oh TJ,Moon JY,Hur KY,Ko SH,Kim HJ,Kim T,Lee DW,Moon MK,Committee of Clinical Practice Guideline, Korean Diabetes Association.,Committee of the Cooperative Studies, Korean Society of Nephrology.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a major cause of liver-related morbidity and mortality. The underlying mechanisms of disease progression remain poorly understood, and primary therapy of NAFLD is not yet established. We investigated the effects of dietary oleate on the ...

journal_title：Diabetes & metabolism journal

authors： Lee JY,Moon JH,Park JS,Lee BW,Kang ES,Ahn CW,Lee HC,Cha BS

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:In order to overcome the limitations of body mass index (BMI) and waist circumference (WC), the z-score of the log-transformed A Body Shape Index (LBSIZ) has recently been introduced. In this study, we analyzed the relationship between the LBSIZ and cardiovascular disease (CVD) in a Korean representative sam...

journal_title：Diabetes & metabolism journal

authors： Chung W,Park JH,Chung HS,Yu JM,Moon S,Kim DS

更新日期：2019-10-01 00:00:00

abstract：:Mitochondrial dysfunction is a hallmark of metabolic diseases such as obesity, type 2 diabetes mellitus, neurodegenerative diseases, and cancers. Dysfunction occurs in part because of altered regulation of the mitochondrial pyruvate dehydrogenase complex (PDC), which acts as a central metabolic node that mediates pyru...

journal_title：Diabetes & metabolism journal

authors： Park S,Jeon JH,Min BK,Ha CM,Thoudam T,Park BY,Lee IK

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The objective of this systematic review and meta-analysis was to determine the effects of omega-3 supplementation on adipocytokine levels in adult prediabetic and diabetic individuals. METHODS:We searched PubMed, Medline, EMBASE, Scopus, Web of Science, Google Scholar, Cochrane Trial Register, World Health ...

journal_title：Diabetes & metabolism journal

authors： Becic T,Studenik C

更新日期：2018-04-01 00:00:00

abstract：:[This corrects the article on p. 46 in vol. 37, PMID: 23439676.]. ...

journal_title：Diabetes & metabolism journal

authors： Bhowmik B,Afsana F,My Diep L,Binte Munir S,Wright E,Mahmood S,Khan AK,Hussain A

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Thyroid disease and metabolic syndrome are both associated with cardiovascular disease. The aim of this study was to investigate the correlation between thyroid hormones and obesity sub-phenotypes using nationwide data from Korea, a country known to be iodine replete. METHODS:This study was based on data ob...

journal_title：Diabetes & metabolism journal

authors： Kim JM,Kim BH,Lee H,Kim EH,Kim M,Kim JH,Jeon YK,Kim SS,Kim IJ,Kim YK

更新日期：2019-12-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and NAFLD severity (incl...

journal_title：Diabetes & metabolism journal

authors： Lee YH,Cho Y,Lee BW,Park CY,Lee DH,Cha BS,Rhee EJ

更新日期：2019-02-01 00:00:00

abstract：:Diabetic cardiomyopathy (DCM), as one of the major cardiac complications in diabetic patients, is known to related with oxidative stress that is due to a severe imbalance between reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) generation and their clearance by antioxidant defense systems. Transcri...

journal_title：Diabetes & metabolism journal

authors： Chen J,Zhang Z,Cai L

更新日期：2014-10-01 00:00:00

abstract：:Adipose tissue, which was once viewed as a simple organ for storage of triglycerides, is now considered an important endocrine organ. Abnormal adipose tissue mass is associated with defects in endocrine and metabolic functions which are the underlying causes of the metabolic syndrome. Many adipokines, hormones secrete...

journal_title：Diabetes & metabolism journal

authors： Corzo C,Griffin PR

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:We investigated whether an intensive individualized reinforcement education program could influence the prevention of hypoglycemic events in patients with type 2 diabetes. METHODS:From March 2013 to September 2013, patients aged 35 to 75 years with type 2 diabetes who had not previously participated in diab...

journal_title：Diabetes & metabolism journal

authors： Yong YM,Shin KM,Lee KM,Cho JY,Ko SH,Yoon MH,Kim TW,Jeong JH,Park YM,Ko SH,Ahn YB

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Latent autoimmune diabetes in adults (LADA) refers to a specific type of diabetes characterized by adult onset, presence of islet auto-antibodies, insulin independence at the time of diagnosis, and rapid decline in β-cell function. The prevalence of LADA among patients with type 2 diabetes varies from 2% to ...

journal_title：Diabetes & metabolism journal

authors： Hwangbo Y,Kim JT,Kim EK,Khang AR,Oh TJ,Jang HC,Park KS,Kim SY,Lee HK,Cho YM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the influences of visceral adiposity on cardiovascular autonomic neuropathy (CAN) in patients with type 2 diabetes mellitus. METHODS:Two hundred eleven patients with type 2 diabetes participated in this study. Anthropometric and metabolic parameters were measured, an...

journal_title：Diabetes & metabolism journal

authors： Jang EH,Kim NY,Park YM,Kim MK,Baek KH,Song KH,Lee KW,Kwon HS

更新日期：2012-08-01 00:00:00