Trends in the Incidence, Prevalence, and Mortality of End-Stage Kidney Disease in South Korea.

abstract：BACKGROUND:Some patients admitted to hospitals for glycemic control experience hypoglycemia despite regular meals and despite adhering to standard blood glucose control protocols. Different factors can have a negative impact on blood glucose control and prognosis after discharge. This study investigated risk factors fo...

journal_title：Diabetes & metabolism journal

authors： Lee J,Kim TM,Kim H,Lee SH,Cho JH,Lee H,Yim HW,Yoon KH,Kim HS

更新日期：2020-08-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is an endocrine hormone that is primarily expressed in the liver and exerts beneficial effects on obesity and related metabolic diseases. In addition to its remarkable pharmacologic actions, the physiological roles of FGF21 include the maintenance of energy homeostasis in the body i...

journal_title：Diabetes & metabolism journal

authors： Kim KH,Lee MS

更新日期：2014-08-01 00:00:00

abstract：:Despite overall reductions in heart disease prevalence, the risk of developing heart failure has remained 2-fold greater among people with diabetes. Growing evidence has supported that fluctuations in glucose level and uptake contribute to cardiovascular disease (CVD) by modifying proteins, DNA, and gene expression. I...

journal_title：Diabetes & metabolism journal

authors： Brahma MK,Pepin ME,Wende AR

更新日期：2017-02-01 00:00:00

abstract：:In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various ...

journal_title：Diabetes & metabolism journal

authors： Rhee SY,Kim YS

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Although many anti-diabetic drugs have been used to control hyperglycemia for decades, the efficacy of commonly-used oral glucose-lowering agents in Korean type 2 diabetic patients has yet to be clearly demonstrated. METHODS:We evaluated the efficacy of glimepiride, metformin, and rosiglitazone as initial t...

journal_title：Diabetes & metabolism journal

authors： Yoon KH,Shin JA,Kwon HS,Lee SH,Min KW,Ahn YB,Yoo SJ,Ahn KJ,Park SW,Lee KW,Sung YA,Park TS,Kim MS,Kim YK,Nam MS,Kim HS,Park IeB,Park JS,Woo JT,Son HY

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:A latent cytomegalovirus (CMV) cause chronic inflammation through undesirable inflation of cell-mediated immune response. CMV immunoglobulin G has been associated with cardiovascular disease and type 1 diabetes mellitus. We evaluated impact of CMV diseases on new-onset type 2 diabetes mellitus (T2DM). METHO...

journal_title：Diabetes & metabolism journal

authors： Yoo SG,Han KD,Lee KH,La Y,Kwon DE,Han SH

更新日期：2019-12-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and NAFLD severity (incl...

journal_title：Diabetes & metabolism journal

authors： Lee YH,Cho Y,Lee BW,Park CY,Lee DH,Cha BS,Rhee EJ

更新日期：2019-02-01 00:00:00

abstract：:As the number of individuals with non-alcoholic fatty liver disease (NAFLD) has increased, the influence of NAFLD on other metabolic diseases has been highlighted. Accumulating epidemiologic evidence indicates that NAFLD not only affects the liver but also increases the risk of extra-hepatic diseases such as type 2 di...

journal_title：Diabetes & metabolism journal

authors： Han E,Lee YH

更新日期：2017-12-01 00:00:00

abstract：:Several polymers were used to delivery genes to diabetic animals. Polyaminobutyl glycolic acid was utilized to deliver IL-10 plasmid DNA to prevent autoimmune insulitis of non-obese diabetic (NOD) mouse. Polyethylene glycol grafted polylysine was combined with antisense glutamic acid decarboxylase (GAD) MRNA to repres...

journal_title：Diabetes & metabolism journal

authors： Kim SW

更新日期：2011-08-01 00:00:00

abstract：:There are many studies on the prevalence, clinical characteristics, and economic burden of diabetes across the past four decades in Korea. Nonetheless, there is a dearth of nationwide study regarding diabetes encompassing all age group. Eight years ago, the Committee on the Epidemiology of Diabetes Mellitus of Korean ...

journal_title：Diabetes & metabolism journal

authors： Task Force Team for Basic Statistical Study of Korean Diabetes Mellitus of Korean Diabetes Association.,Park IeB,Kim J,Kim DJ,Chung CH,Oh JY,Park SW,Lee J,Choi KM,Min KW,Park JH,Son HS,Ahn CW,Kim H,Lee S,Lee IB,Choi I,B

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Food exchange lists are one of the main methods of nutritional education. However, Korean food exchange lists have not been revised since 1994. Therefore, we surveyed the opinions of diabetes educators and patients with diabetes regarding the need for revision of the current food exchange lists. METHODS:For...

journal_title：Diabetes & metabolism journal

authors： Cho JW,Kweon MR,Park YM,Woo MH,Yoo HS,Lim JH,Koo BK,Kim CH,Kim HJ,Park JS,Shin CH,Won KC,Lim S,Jang HC

更新日期：2011-04-01 00:00:00

abstract：:A growing body of evidence suggests that hyperglycemia-induced oxidative stress plays an important role in diabetic complications, especially β-cell dysfunction and failure. Under physiological conditions, reactive oxygen species serve as second messengers that facilitate signal transduction and gene expression in pan...

journal_title：Diabetes & metabolism journal

authors： Karunakaran U,Park KG

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) is associated with an increased risk for dementia. The effects of hypoglycemia on dementia are controversial. Thus, we evaluated whether hypoglycemia increases the risk for dementia in senior patients with T2DM. METHODS:We used the Korean National Health Insurance Service Sen...

journal_title：Diabetes & metabolism journal

authors： Kim YG,Park DG,Moon SY,Jeon JY,Kim HJ,Kim DJ,Lee KW,Han SJ

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Voglibose, an α-glucosidase inhibitor, inhibits breakdown of complex carbohydrates into simple sugar units in intestine. Studies showed that voglibose metabolism in the liver might be negligible due to its poor intestinal absorption. Numerous microorganisms live in intestine and have several roles in metabol...

journal_title：Diabetes & metabolism journal

authors： Nepal MR,Kang MJ,Kim GH,Cha DH,Kim JH,Jeong TC

更新日期：2020-12-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic steatohepatitis (NASH). A combination of environmental factors, h...

journal_title：Diabetes & metabolism journal

authors： Povero D,Feldstein AE

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a major cause of liver-related morbidity and mortality. The underlying mechanisms of disease progression remain poorly understood, and primary therapy of NAFLD is not yet established. We investigated the effects of dietary oleate on the ...

journal_title：Diabetes & metabolism journal

authors： Lee JY,Moon JH,Park JS,Lee BW,Kang ES,Ahn CW,Lee HC,Cha BS

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:This is a subgroup analysis of Korean patients from a phase 3 clinical trial investigating the efficacy and safety of ipragliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin. METHODS:This multicenter, placebo-controlled, double-blind, parallel-group study was carried o...

journal_title：Diabetes & metabolism journal

authors： Min KW,Ku BJ,Lee JH,Kim MS,Ahn KJ,Lee MK,Kokubo S,Yoshida S,Cho HJ,Cha BS

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Chronic exposure to elevated levels of free fatty acids contributes to pancreatic β-cell dysfunction. Although it is well known that metformin induces cellular energy depletion and a concomitant activation of AMP-activated protein kinase (AMPK) through inhibition of the respiratory chain, previous studies ha...

journal_title：Diabetes & metabolism journal

authors： Kim HI,Lee JS,Kwak BK,Hwang WM,Kim MJ,Kim YB,Chung SS,Park KS

更新日期：2019-12-01 00:00:00

abstract：:This corrects the article on p. 3 in vol. 42, PMID: 29504302. ...

journal_title：Diabetes & metabolism journal

authors： Iqbal A,Novodvorsky P,Heller SR

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The prevalence of novel type 1 diabetes mellitus (T1DM) antibodies targeting eukaryote translation elongation factor 1 alpha 1 autoantibody (EEF1A1-AAb) and ubiquitin-conjugating enzyme 2L3 autoantibody (UBE2L3-AAb) has been shown to be negatively correlated with age in T1DM subjects. Therefore, we aimed to ...

journal_title：Diabetes & metabolism journal

authors： Kim EG,Kwak SH,Hwang D,Yi EC,Park KS,Koo BK,Kim KM

更新日期：2016-04-01 00:00:00

abstract：:This corrects the article on p. 218 in vol. 39, PMID: 26124992. ...

journal_title：Diabetes & metabolism journal

authors： Natasha K,Hussain A,Azad Khan AK,Bhowmik B

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:To explore the efficacy and safety of switching from once-daily basal insulin therapy to once-daily pre-meal injection insulin degludec/insulin aspart (IDegAsp) with respect to the glycemic control of participants with type 2 diabetes mellitus (T2DM). METHODS:In this multicenter, open-label, prospective, ra...

journal_title：Diabetes & metabolism journal

authors： Cho KY,Nakamura A,Oba-Yamamoto C,Tsuchida K,Yanagiya S,Manda N,Kurihara Y,Aoki S,Atsumi T,Miyoshi H

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:To investigate the clinical results of sitagliptin (SITA) and the characteristics of the treatment failure group or of low responders to SITA. METHODS:A retrospective study of type 2 diabetic patients reviewed 99 cases, including 12 treatment failure cases, who stopped SITA because of worsening patients' co...

journal_title：Diabetes & metabolism journal

authors： Kim WJ,Park CY,Jeong EH,Seo JY,Seol JS,Park SE,Rhee EJ,Lee WY,Oh KW,Park SW,Kim SW

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was an in vitro investigation of the effect of high glucose concentration on adipogenesis, as prolonged hyperglycemia alters adipocyte differentiation. METHODS:3T3-L1 preadipocytes differentiated in the presence of varying concentrations of glucose (25, 45, 65, 85, and 105 mM) were ass...

journal_title：Diabetes & metabolism journal

authors： Shilpa K,Dinesh T,Lakshmi BS

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Thyroid disease and metabolic syndrome are both associated with cardiovascular disease. The aim of this study was to investigate the correlation between thyroid hormones and obesity sub-phenotypes using nationwide data from Korea, a country known to be iodine replete. METHODS:This study was based on data ob...

journal_title：Diabetes & metabolism journal

authors： Kim JM,Kim BH,Lee H,Kim EH,Kim M,Kim JH,Jeon YK,Kim SS,Kim IJ,Kim YK

更新日期：2019-12-01 00:00:00

abstract：:Cyclic adenosine monophosphate (cAMP) signaling is critical for regulating metabolic homeostasis in mammals. In particular, transcriptional regulation by cAMP response element-binding protein (CREB) and its coactivator, CREB-regulated transcription coactivator (CRTC), is essential for controlling the expression of cri...

journal_title：Diabetes & metabolism journal

authors： Han HS,Kwon Y,Koo SH

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Women with one abnormal value (OAV) in a 100 g oral glucose tolerance test (OGTT) during pregnancy are reported to have an increased risk of adverse pregnancy outcomes. However, there is limited data about whether women with OAV will progress to gestational diabetes mellitus (GDM) when the OGTT is repeated. ...

journal_title：Diabetes & metabolism journal

authors： Kang S,Kim MH,Kim MY,Hong JS,Kwak SH,Choi SH,Lim S,Park KS,Jang HC

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Some patients with type 2 diabetes mellitus (T2DM) do not develop diabetic kidney disease (DKD) despite the presence of advanced diabetic retinopathy (DR). We aimed to investigate the presence of DKD and its risk factors in patients with T2DM and advanced DR. METHODS:We conducted a cross-sectional study in ...

journal_title：Diabetes & metabolism journal

authors： Yun KJ,Kim HJ,Kim MK,Kwon HS,Baek KH,Roh YJ,Song KH

更新日期：2016-12-01 00:00:00

abstract：:Adipose tissue, which was once viewed as a simple organ for storage of triglycerides, is now considered an important endocrine organ. Abnormal adipose tissue mass is associated with defects in endocrine and metabolic functions which are the underlying causes of the metabolic syndrome. Many adipokines, hormones secrete...

journal_title：Diabetes & metabolism journal

authors： Corzo C,Griffin PR

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:We evaluated decreases in glycosylated hemoglobin (HbA1c) achieved by reducing carbohydrate from various sources in type 2 diabetes mellitus patients. METHODS:We followed up 138 male and 107 female outpatients on a moderate low-carbohydrate diet without diabetic medication for 6 months. Changes in carbohydr...

journal_title：Diabetes & metabolism journal

authors： Haimoto H,Watanabe S,Maeda K,Murase T,Wakai K

更新日期：2020-07-21 00:00:00