The Role of Advanced Glycation End Products in Diabetic Vascular Complications.

Abstract:

:In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications.

journal_name

Diabetes Metab J

authors

Rhee SY,Kim YS

doi

10.4093/dmj.2017.0105

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

188-195

issue

3

eissn

2233-6079

issn

2233-6087

pii

42.e17

journal_volume

42

pub_type

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