Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015).

abstract：:The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient utilization of fatty acid and glucose, which is controlled by the PDC. The PDC converts pyruvate...

journal_title：Diabetes & metabolism journal

authors： Lee IK

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is a chronic disease and one of the main causes of mortality in developing countries. The main objective of treating all chronic diseases, of course, is to improve well-being and attain a satisfactory quality of life (QOL). The major goal of this study is comparison of attitude toward QOL i...

journal_title：Diabetes & metabolism journal

authors： Hashemi Hefz Abad F,Shabany Hamedan M

更新日期：2011-08-01 00:00:00

abstract：:Cyclic adenosine monophosphate (cAMP) signaling is critical for regulating metabolic homeostasis in mammals. In particular, transcriptional regulation by cAMP response element-binding protein (CREB) and its coactivator, CREB-regulated transcription coactivator (CRTC), is essential for controlling the expression of cri...

journal_title：Diabetes & metabolism journal

authors： Han HS,Kwon Y,Koo SH

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:A 64-slice multidetector computed tomography (MDCT) is well known to be a useful noninvasive form of angiography for the general population, but not for certain patients with diabetes. The aim of this study was to investigate the diagnostic accuracy and usefulness of 64-slice MDCT coronary angiography for de...

journal_title：Diabetes & metabolism journal

authors： Moon JS,Yoon JS,Won KC,Cho IH,Lee HW

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a major cause of liver-related morbidity and mortality. The underlying mechanisms of disease progression remain poorly understood, and primary therapy of NAFLD is not yet established. We investigated the effects of dietary oleate on the ...

journal_title：Diabetes & metabolism journal

authors： Lee JY,Moon JH,Park JS,Lee BW,Kang ES,Ahn CW,Lee HC,Cha BS

更新日期：2011-10-01 00:00:00

abstract：:My professional journey to understand the glucose homeostasis began in the 1990s, starting from cloning of the promoter region of glucose transporter type 2 (GLUT2) gene that led us to establish research foundation of my group. When I was a graduate student, I simply thought that hyperglycemia, a typical clinical mani...

journal_title：Diabetes & metabolism journal

authors： Ahn YH

更新日期：2018-12-01 00:00:00

abstract：:Care of the elderly population with diabetes may not be restricted to the management of hyperglycemia, associated risk factors, and specific diabetic complications. An integrated approach should also include the assessment and management of gerontological problems. Both diabetes mellitus and aging interact toward the ...

journal_title：Diabetes & metabolism journal

authors： Yoo HJ

更新日期：2017-06-01 00:00:00

abstract：:This corrects the article on p. 218 in vol. 39, PMID: 26124992. ...

journal_title：Diabetes & metabolism journal

authors： Natasha K,Hussain A,Azad Khan AK,Bhowmik B

更新日期：2016-02-01 00:00:00

abstract：:Adipose tissue, which was once viewed as a simple organ for storage of triglycerides, is now considered an important endocrine organ. Abnormal adipose tissue mass is associated with defects in endocrine and metabolic functions which are the underlying causes of the metabolic syndrome. Many adipokines, hormones secrete...

journal_title：Diabetes & metabolism journal

authors： Corzo C,Griffin PR

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Rebaudioside A and erythritol are nonnutritive sweeteners. There have been several studies of their glycemic effects, but the outcomes remain controversial. The purpose of this study was to evaluate the glycemic effects of rebaudioside A and erythritol as a sweetener in people with glucose intolerance. METH...

journal_title：Diabetes & metabolism journal

authors： Shin DH,Lee JH,Kang MS,Kim TH,Jeong SJ,Kim CH,Kim SS,Kim IJ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:This study aimed to design a simple surrogate marker (i.e., predictor) of the minimal model glucose effectiveness (SG), namely calculated SG (CSG), from a short insulin-modified intravenous glucose tolerance test (IM-IVGTT), and then to apply it to study women with previous gestational diabetes mellitus (pGD...

journal_title：Diabetes & metabolism journal

authors： Morettini M,Castriota C,Göbl C,Kautzky-Willer A,Pacini G,Burattini L,Tura A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Some patients with type 2 diabetes mellitus (T2DM) do not develop diabetic kidney disease (DKD) despite the presence of advanced diabetic retinopathy (DR). We aimed to investigate the presence of DKD and its risk factors in patients with T2DM and advanced DR. METHODS:We conducted a cross-sectional study in ...

journal_title：Diabetes & metabolism journal

authors： Yun KJ,Kim HJ,Kim MK,Kwon HS,Baek KH,Roh YJ,Song KH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Food exchange lists are one of the main methods of nutritional education. However, Korean food exchange lists have not been revised since 1994. Therefore, we surveyed the opinions of diabetes educators and patients with diabetes regarding the need for revision of the current food exchange lists. METHODS:For...

journal_title：Diabetes & metabolism journal

authors： Cho JW,Kweon MR,Park YM,Woo MH,Yoo HS,Lim JH,Koo BK,Kim CH,Kim HJ,Park JS,Shin CH,Won KC,Lim S,Jang HC

更新日期：2011-04-01 00:00:00

abstract：:Genome wide association analyses have revealed large numbers of common variants influencing predisposition to type 2 diabetes and related phenotypes. These studies have predominantly featured European populations, but are now being extended to samples from a wider range of ethnic groups. The transethnic analysis of as...

journal_title：Diabetes & metabolism journal

authors： McCarthy MI

更新日期：2011-04-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic steatohepatitis (NASH). A combination of environmental factors, h...

journal_title：Diabetes & metabolism journal

authors： Povero D,Feldstein AE

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The aim of this study is to investigate the cardio-metabolic parameters and surrogate markers of insulin resistance in a discordant group of type 2 diabetes (T2DM) subjects who satisfy the Adults Treatment Panel (ATP) III criteria, but not the International Diabetes Federation (IDF) criteria, for metabolic s...

journal_title：Diabetes & metabolism journal

authors： Lee SR,Han Y,Kim JW,Park JY,Kim JM,Suh S,Park MK,Lee HJ,Kim DK

更新日期：2012-10-01 00:00:00

abstract：:Diabetes is a leading cause of end-stage renal disease. Therefore, prevention of renal dysfunction is an important treatment goal in the management of diabetes. The data of landmark cardiovascular outcome trials of sodium-glucose cotransporter-2 (SGLT2) inhibitor showed profound reno-protective effects. The Korean Dia...

journal_title：Diabetes & metabolism journal

authors： Oh TJ,Moon JY,Hur KY,Ko SH,Kim HJ,Kim T,Lee DW,Moon MK,Committee of Clinical Practice Guideline, Korean Diabetes Association.,Committee of the Cooperative Studies, Korean Society of Nephrology.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was an in vitro investigation of the effect of high glucose concentration on adipogenesis, as prolonged hyperglycemia alters adipocyte differentiation. METHODS:3T3-L1 preadipocytes differentiated in the presence of varying concentrations of glucose (25, 45, 65, 85, and 105 mM) were ass...

journal_title：Diabetes & metabolism journal

authors： Shilpa K,Dinesh T,Lakshmi BS

更新日期：2013-06-01 00:00:00

abstract：:As the number of individuals with non-alcoholic fatty liver disease (NAFLD) has increased, the influence of NAFLD on other metabolic diseases has been highlighted. Accumulating epidemiologic evidence indicates that NAFLD not only affects the liver but also increases the risk of extra-hepatic diseases such as type 2 di...

journal_title：Diabetes & metabolism journal

authors： Han E,Lee YH

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Despite the confluence of multiple cardiovascular risk factors, subclinical atherosclerotic damage and cardiovascular events remain extremely rare in adults with Down syndrome (DS). We aim to determine the prevalence of obesity and metabolic disorders in an adult cohort with DS and to compare our findings wi...

journal_title：Diabetes & metabolism journal

authors： Real de Asua D,Parra P,Costa R,Moldenhauer F,Suarez C

更新日期：2014-12-01 00:00:00

abstract：:A growing body of evidence suggests that hyperglycemia-induced oxidative stress plays an important role in diabetic complications, especially β-cell dysfunction and failure. Under physiological conditions, reactive oxygen species serve as second messengers that facilitate signal transduction and gene expression in pan...

journal_title：Diabetes & metabolism journal

authors： Karunakaran U,Park KG

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:To explore the efficacy and safety of switching from once-daily basal insulin therapy to once-daily pre-meal injection insulin degludec/insulin aspart (IDegAsp) with respect to the glycemic control of participants with type 2 diabetes mellitus (T2DM). METHODS:In this multicenter, open-label, prospective, ra...

journal_title：Diabetes & metabolism journal

authors： Cho KY,Nakamura A,Oba-Yamamoto C,Tsuchida K,Yanagiya S,Manda N,Kurihara Y,Aoki S,Atsumi T,Miyoshi H

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the influences of visceral adiposity on cardiovascular autonomic neuropathy (CAN) in patients with type 2 diabetes mellitus. METHODS:Two hundred eleven patients with type 2 diabetes participated in this study. Anthropometric and metabolic parameters were measured, an...

journal_title：Diabetes & metabolism journal

authors： Jang EH,Kim NY,Park YM,Kim MK,Baek KH,Song KH,Lee KW,Kwon HS

更新日期：2012-08-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is an endocrine hormone that is primarily expressed in the liver and exerts beneficial effects on obesity and related metabolic diseases. In addition to its remarkable pharmacologic actions, the physiological roles of FGF21 include the maintenance of energy homeostasis in the body i...

journal_title：Diabetes & metabolism journal

authors： Kim KH,Lee MS

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The second derivative of the finger photoplethysmogram (SDPTG) is an indicator of arterial stiffness. The present study was conducted to clarify the factor structure of indices of the SDPTG in combination with components of the metabolic syndrome (MetS), to elucidate the significance of the SDPTG among vario...

journal_title：Diabetes & metabolism journal

authors： Kawada T,Otsuka T

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Diabetes self-management education and reinforcement are important for effective management of the disease. We investigated the effectiveness of interactive small-group education on glycemic, blood pressure, and lipid levels. METHODS:For this study, 207 type 2 diabetes patients with suboptimal glycemic cont...

journal_title：Diabetes & metabolism journal

authors： Choi MJ,Yoo SH,Kim KR,Bae YM,Ahn SH,Kim SS,Min SA,Choi JS,Lee SE,Moon YJ,Rhee EJ,Park CY,Lee WY,Oh KW,Park SW,Kim SW

更新日期：2011-12-01 00:00:00

abstract：:Latent autoimmune diabetes in adults (LADA) is a heterogeneous disease characterized by a less intensive autoimmune process and a broad clinical phenotype compared to classical type 1 diabetes mellitus (T1DM), sharing features with both type 2 diabetes mellitus (T2DM) and T1DM. Since patients affected by LADA are init...

journal_title：Diabetes & metabolism journal

authors： Pieralice S,Pozzilli P

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The prevalence of novel type 1 diabetes mellitus (T1DM) antibodies targeting eukaryote translation elongation factor 1 alpha 1 autoantibody (EEF1A1-AAb) and ubiquitin-conjugating enzyme 2L3 autoantibody (UBE2L3-AAb) has been shown to be negatively correlated with age in T1DM subjects. Therefore, we aimed to ...

journal_title：Diabetes & metabolism journal

authors： Kim EG,Kwak SH,Hwang D,Yi EC,Park KS,Koo BK,Kim KM

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:We investigated whether an intensive individualized reinforcement education program could influence the prevention of hypoglycemic events in patients with type 2 diabetes. METHODS:From March 2013 to September 2013, patients aged 35 to 75 years with type 2 diabetes who had not previously participated in diab...

journal_title：Diabetes & metabolism journal

authors： Yong YM,Shin KM,Lee KM,Cho JY,Ko SH,Yoon MH,Kim TW,Jeong JH,Park YM,Ko SH,Ahn YB

更新日期：2015-04-01 00:00:00

abstract：:Despite overall reductions in heart disease prevalence, the risk of developing heart failure has remained 2-fold greater among people with diabetes. Growing evidence has supported that fluctuations in glucose level and uptake contribute to cardiovascular disease (CVD) by modifying proteins, DNA, and gene expression. I...

journal_title：Diabetes & metabolism journal

authors： Brahma MK,Pepin ME,Wende AR

更新日期：2017-02-01 00:00:00