A competing-risks nomogram for predicting probability of death from CRC in Chinese Han patients with Stage I-III CRC.

abstract：Background:The impact of age as a prognostic factor for patients with colorectal cancer (CRC) remains controversial, possibly due to heterogeneity between studies in terms of patient numbers, percentage of patients undergoing curative resection, percentage of patients receiving neoadjuvant therapy, or failure to adjust...

journal_title：Japanese journal of clinical oncology

authors： Chou CL,Tseng CJ,Shiue YL

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:In Japan, there had been no prospective clinical studies conducted in terms of modified FOLFOX6 + bevacizumab therapy. We performed a post-marketing Phase II multicenter clinical study to examine the efficacy and safety of this regimen as first-line therapy for Japanese patients with advanced/recurrent colore...

journal_title：Japanese journal of clinical oncology

authors： Nishina T,Takano Y,Denda T,Yasui H,Takeda K,Ura T,Esaki T,Okuyama Y,Kondo K,Takahashi Y,Sugiyama Y,Muro K

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Cytokeratins (CKs) 19 and 20 have been used as targets for detecting cancer cells. We attempted to detect circulating cancer cells in patients with gastric cancer using a high-sensitivity reverse transcriptase-polymerase chain reaction (RT-PCR) assay for CK transcripts. METHODS:RT-PCR for CK 19 and CK 20 wa...

journal_title：Japanese journal of clinical oncology

authors： Majima T,Ichikura T,Takayama E,Chochi K,Mochizuki H

更新日期：2000-11-01 00:00:00

abstract：:We report on an inflammatory pseudotumor of the spleen. A 72-year-old woman visited our hospital complaining of nausea. Physical examination and laboratory investigations were unremarkable. Ultrasonography, computed tomography, magnetic resonance imaging and angiography showed a hypovascular splenic mass measuring abo...

journal_title：Japanese journal of clinical oncology

authors： Noguchi H,Kondo H,Kondo M,Shiraiwa M,Monobe Y

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To date, there are few reliable markers to distinguish tumors with aggressive characteristics in upper tract urothelial carcinoma. The purpose of this study was to identify a biomarker related to genetic instability (chromosomal instability or microsatellite instability) with prognostic value, in patients wit...

journal_title：Japanese journal of clinical oncology

authors： Yamamoto Y,Oga A,Akao J,Misumi T,Fuji N,Kobayashi K,Kawai Y,Inoue R,Hirata H,Matsumoto H,Nagao K,Sakano S,Matsuyama H

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To confirm the safety and efficacy of everolimus in patients with unresectable or metastatic RCC. METHODS:Patients with unresectable or metastatic RCC were included and were followed for up to 1 year from the start of everolimus. The study was conducted at 618 investigational sites in Japan from March 2010 t...

journal_title：Japanese journal of clinical oncology

authors： Akaza H,Kurihara R,Katsura A,Harumiya M,Ushida N

更新日期：2019-10-01 00:00:00

abstract：:The localization of acidic fibroblast growth factor (aFGF) and basic fibroblast growth factor (bFGF) was investigated immunohistochemically in human benign and malignant thyroid lesions. Immunostaining for aFGF and bFGF displayed diffuse or granular deposits of the reaction products in the cytoplasm of neoplastic cell...

journal_title：Japanese journal of clinical oncology

authors： Kodama M,Daa T,Kashima K,Yokoyama S,Nakayama I,Noguchi S

更新日期：1994-04-01 00:00:00

abstract：:A Phase I/II trial of chemoradiotherapy concurrent with S-1 plus mitomycin C in patients with clinical Stage II/III squamous cell carcinoma of the anal canal was started in Japan. The aim of this trial is to determine the recommended dose of S-1 combined with a fixed dose of mitomycin C plus radiotherapy in Phase I an...

journal_title：Japanese journal of clinical oncology

authors： Takashima A,Shimada Y,Hamaguchi T,Ito Y,Nakano A,Nakamura K,Shibata T,Fukuda H,Moriya Y,Colorectal Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2011-05-01 00:00:00

abstract：:Adult extrarenal nephroblastomas (Wilms' tumor) are extremely rare tumors. They show a higher incidence of non-seminomatous elements and these so-called 'teratoid' Wilms' tumors are suggested to be of germ cell origin. To date, however, the number of reported cases with gonadal teratoma containing nephroblastoma is ve...

journal_title：Japanese journal of clinical oncology

authors： Keskin S,Ekenel M,Başaran M,Aksu C,Kiliçaslan I,Tunç M,Bavbek S

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:We evaluated the feasibility of combination chemotherapy with paclitaxel, doxorubicin and cisplatin without prophylactic granulocyte colony-stimulating factor injection for intermediate-to-high-risk or recurrent endometrial cancer. METHODS:Women with histologically confirmed FIGO Stages I-II with >1/2 myomet...

journal_title：Japanese journal of clinical oncology

authors： Nagao S,Nishikawa T,Hanaoka T,Kurosaki A,Iwasa N,Hasegawa K,Fujiwara K

更新日期：2014-11-01 00:00:00

abstract：:Subglottic carcinoma is rare and has a poor prognosis. It is usually treated with surgical resection, external beam irradiation (EBR) and/or a combination of both. Intraluminal irradiation (IR) as a curative treatment for subglottic carcinoma has never been reported. We report a case of subglottic carcinoma in a 66-ye...

journal_title：Japanese journal of clinical oncology

authors： Wakisaka M,Fuwa N,Matsumoto A,Tachibana H,Kodaira T,Furutani K,Kamata M,Mori H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:A high response rate has been reported for chemotherapy combining irinotecan (CPT-11) and cisplatin (CDDP) against advanced gastric cancer. The strong anti-tumor activity of this regimen makes it very attractive as a preoperative chemotherapy. We conducted a preliminary study on preoperative chemotherapy wit...

journal_title：Japanese journal of clinical oncology

authors： Yamao T,Ohta K,Ohyama S,Ishihara S,Chin K,Maruyama M,Takahashi T,Nakajima T

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Usually, total and filtered platinum concentrations in plasma are monitored after cisplatin administration. However, these concentrations represent a mixture of unchanged cisplatin and metabolites. In this work, we studied population pharmacokinetic analysis based on these platinum concentrations. METHODS:T...

journal_title：Japanese journal of clinical oncology

authors： Hanada K,Nishijima K,Ogata H,Atagi S,Kawahara M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the prognostic importance of the sequencing of radiation therapy and chemotherapy after mastectomy in high-risk premenopausal women with breast cancer in addition to other known prognostic factors in the literature. METHODS:In this retrospective study, 176 premenopau...

journal_title：Japanese journal of clinical oncology

authors： Cakir S,Gursel B,Meydan D,Yildiz L

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Stage III colorectal cancer is an indication for adjuvant chemotherapy; however, there is no definite view on the selection of regimen. If the recurrence can be predicted, it can serve as the indicator of regimen selection. The present study aimed to predict the recurrence of stage III colorectal cancer by c...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa S,Sawayama H,Matsuo A,Uchino R,Honda S,Hirota M,Baba H

更新日期：2019-03-01 00:00:00

abstract：:Cancer is the leading cause of mortality in Singapore. The age-standardized incidence rates continue to increase as the population grows and ages, and the influence of environmental and lifestyle choices bear their consequences. The increase is most marked in colorectal, breast and prostate cancers, mirroring the most...

journal_title：Japanese journal of clinical oncology

authors： Teo MC,Soo KC

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Oral fluoropyrimidine plus cisplatin is a standard treatment for advanced gastric cancer, but patients with severe peritoneal metastasis often cannot tolerate this regimen. The aim of this study was to assess the feasibility of fluorouracil, l-leucovorin and paclitaxel therapy in such patients. METHODS:In th...

journal_title：Japanese journal of clinical oncology

authors： Iwasa S,Goto M,Yasui H,Nishina T,Takahari D,Nakayama N,Taira K,Kusaba H,Fuse N,Hironaka S,Shimada Y,Nakajima TE

更新日期：2012-09-01 00:00:00

abstract：:A review of the present status of adjuvant chemotherapy for gastric cancer in Japan has been made. The single use of mitomycin C (MMC) after curative gastrectomy, a multidrug combination of MMC, 5-fluorouracil (5FU) and cytosine arabinoside (CA) (MFC therapy), and a combination of inductive MFC followed by maintenance...

journal_title：Japanese journal of clinical oncology

authors： Nakajima T

更新日期：1990-03-01 00:00:00

abstract：:We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a diagnosis of acute pulmonary embolism was made at a local hospital and she received anticoagulation and thrombolysis therap...

journal_title：Japanese journal of clinical oncology

authors： Uchida A,Tabata M,Kiura K,Tanimoto Y,Kanehiro A,Aoe M,Ohohara N,Ueoka H,Tanimoto M

更新日期：2005-07-01 00:00:00

abstract：Background:The prevalence and molecular characteristics of defective mismatch repair epithelial ovarian cancers in the Japanese population have scarcely been investigated. Methods:Immunohistochemistry for mismatch repair proteins (MLH1, MSH2, MSH6 and PMS2) was performed in formalin-fixed paraffin-embedded sections pr...

journal_title：Japanese journal of clinical oncology

authors： Tajima Y,Eguchi H,Chika N,Nagai T,Dechamethakun S,Kumamoto K,Tachikawa T,Akagi K,Tamaru JI,Seki H,Okazaki Y,Ishida H

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Emotional distress is considered to be higher in patients with head and neck cancer than other types of cancer. The present study aimed to identify predictors of the postoperative levels of depression in patients with head and neck cancer who have undergone surgery. METHODS:Postoperative levels of depression...

journal_title：Japanese journal of clinical oncology

authors： Adachi Y,Kimura H,Sato N,Nagashima W,Nakamura K,Aleksic B,Yoshida K,Fujimoto Y,Nakashima T,Ozaki N

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Breast cancer is a heterogeneous disease. The aim of this prospective study, in which fluorescence in situ hybridization was used to determine human epidermal growth factor receptor 2 status in primary breast cancers and in the lymph node metastases, was to verify the stability of human epidermal growth facto...

journal_title：Japanese journal of clinical oncology

authors： Aoyama K,Kamio T,Nishikawa T,Kameoka S

更新日期：2010-07-01 00:00:00

abstract：:It is important to examine variation in the treatment effects of patients with esophageal cancer in order to generalize treatment outcomes. We aimed to investigate the range of prognostic differences among hospitals in the treatment of locally advanced esophageal cancer. The JCOG0303 study compared the efficacy of rad...

journal_title：Japanese journal of clinical oncology

authors： Hamamoto Y,Mizusawa J,Katayama H,Nakamura K,Kato K,Tsubosa Y,Ishikura S,Igaki H,Shinoda M,Fukuda H,Kitagawa Y,Ando N

更新日期：2016-04-01 00:00:00

abstract：:A Phase II trial was initiated in Japan to evaluate the efficacy and safety of preoperative chemotherapy with docetaxel, cisplatin and S-1 for gastric cancer with extensive lymph node metastasis. Patients are eligible to participate in the study if they have para-aortic lymph node metastases (stations no. 16a2/16b1) a...

journal_title：Japanese journal of clinical oncology

authors： Katayama H,Ito S,Sano T,Takahari D,Mizusawa J,Boku N,Tsuburaya A,Terashima M,Sasako M,Stomach Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The disease status of axillary lymph nodes at diagnosis is the most powerful predictor of prognosis for patients with breast cancer. Axillary lymph node dissection (ALND) has been the standard treatment. Recently, lymphatic mapping and sentinel lymph node biopsy (SNB) have been suggested as alternatives to A...

journal_title：Japanese journal of clinical oncology

authors： Koizumi M,Makita M,Yoshimoto M,Kasumi F,Sakamoto G,Ogata E

更新日期：2002-12-01 00:00:00

abstract：:The positive correlation between smoking and cancer risk is well estimated in sporadic colorectal cancer, whereas little is known with regard to Lynch syndrome-associated colorectal cancer. A total of 118 familial colorectal cancer patients from the Hereditary Nonpolyposis Colorectal Cancer Registry and Genetic Testin...

journal_title：Japanese journal of clinical oncology

authors： Tanakaya K,Furukawa Y,Nakamura Y,Hirata K,Tomita N,Tamura K,Sugano K,Ishioka C,Yoshida T,Ishida H,Watanabe T,Sugihara K,HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum.,Yama

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Low-dose-rate (LDR) brachytherapy is an effective treatment for tongue cancer. However, little is known about the biological mechanism underlying this therapy, characterized by delivery of continuous exposures of LDR irradiation. It is reported that lower microvessel density (MVD), lower Ki-67 index or higher...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Someya M,Nagakura H,Nakata K,Oouchi A,Takagi M,Hareyama M

更新日期：2008-06-01 00:00:00

abstract：:An in vitro monolayer model for cancer invasion was developed, comprising cultured layers of human pleura-derived mesothelial cells (PM cells). The cells were isolated from normal human pleura at autopsy and cultured in RPMI-1640 supplemented with 10% fetal calf serum; they were polygonal in shape, forming a pavement-...

journal_title：Japanese journal of clinical oncology

authors： Horai T,Imamura F,Nakae T,Nakamura S,Mukai M,Shinkai K,Higashino K,Akedo H

更新日期：1992-04-01 00:00:00

abstract：:Recent reports of cancers that produce colony-stimulating factors (CSF) and which are associated with leukocytosis indicate that most are granulocyte CSF-producing tumors. A 71-year-old man with metastatic chest wall tumors from large cell lung cancer with marked leukocytosis and eosinophilia was reported. His maximal...

journal_title：Japanese journal of clinical oncology

authors： Watanabe M,Ono K,Ozeki Y,Tanaka S,Aida S,Okuno Y

更新日期：1998-09-01 00:00:00

abstract：Background:Fluid collection (FC) of lymph or blood may accumulate at the site of excision after surgery for soft tissue sarcoma, with reported incidence rates from 10% to 36%. The purpose of this study is to analyze the impact of FC on local recurrence (LR) and wound complication rates after adjuvant postoperative radi...

journal_title：Japanese journal of clinical oncology

authors： Choi N,Kim JY,Yu T,Kang HC,Kim HS,Kim HJ,Kim IH

更新日期：2018-02-01 00:00:00