A Phase I/II trial of chemoradiotherapy concurrent with S-1 plus mitomycin C in patients with clinical Stage II/III squamous cell carcinoma of anal canal (JCOG0903: SMART-AC).

abstract：BACKGROUND:Regular endoscopic surveillance for Lynch syndrome is reported to reduce colorectal cancer (CRC)-related mortality. However, the appropriate surveillance intervals are still unclear. We evaluated the adequacy of annual colonoscopy and investigated the differences in tumor occurrence rates between individual ...

journal_title：Japanese journal of clinical oncology

authors： Taniguchi F,Tanakaya K,Sugano K,Akagi K,Ishida H,Nagahisa S,Nishimura S,Une Y,Kimura Y,Watanabe M,Utsumi M,Aoki H

更新日期：2020-06-10 00:00:00

abstract：:Cancer is the leading cause of mortality in Singapore. The age-standardized incidence rates continue to increase as the population grows and ages, and the influence of environmental and lifestyle choices bear their consequences. The increase is most marked in colorectal, breast and prostate cancers, mirroring the most...

journal_title：Japanese journal of clinical oncology

authors： Teo MC,Soo KC

更新日期：2013-03-01 00:00:00

abstract：:We encountered a patient with hepatocellular carcinoma (HCC) with peritoneal dissemination and needle tract implantation, both of which were strongly suspected to have been caused by percutaneous needle biopsy. The patient was a 65-year-old man. Partial hepatectomy of subsegment VI had been performed following the dia...

journal_title：Japanese journal of clinical oncology

authors： Takahashi H,Konishi M,Nakagohri T,Inoue K,Takahashi S,Tanizawa Y,Monden M,Kinoshita T

更新日期：2004-09-01 00:00:00

abstract：:There has been no previous report of oxaliplatin administration in patients undergoing hemodialysis. A 65-year-old female with end-stage renal disease who was undergoing hemodialysis presented with anemia in August 2005. She was diagnosed with colon cancer with multiple liver metastases. After colectomy, hepatic arter...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Munakata M,Muto O,Okada R,Mitobe S,Mino M,Ikami I,Sakata Y

更新日期：2007-07-01 00:00:00

abstract：:Trousseau's syndrome (cancer-associated thrombosis) is the second leading cause of death in cancer patients, after death from cancer itself. The risk of a venous thromboembolism is 4- to 7-fold higher in patients with cancer than in those without cancer. The causes of this impaired coagulation are associated with gene...

journal_title：Japanese journal of clinical oncology

authors： Ikushima S,Ono R,Fukuda K,Sakayori M,Awano N,Kondo K

更新日期：2016-03-01 00:00:00

abstract：:An in vitro monolayer model for cancer invasion was developed, comprising cultured layers of human pleura-derived mesothelial cells (PM cells). The cells were isolated from normal human pleura at autopsy and cultured in RPMI-1640 supplemented with 10% fetal calf serum; they were polygonal in shape, forming a pavement-...

journal_title：Japanese journal of clinical oncology

authors： Horai T,Imamura F,Nakae T,Nakamura S,Mukai M,Shinkai K,Higashino K,Akedo H

更新日期：1992-04-01 00:00:00

abstract：:Most terminally ill cancer patients in our hospice ward are referred from hospitals for anticancer treatment. For identical terminally ill cancer patients referred from other hospitals, differences in the accuracy and characteristics of the prognostic prediction of survival by oncologists and palliative care physician...

journal_title：Japanese journal of clinical oncology

authors： Urahama N,Sono J,Yoshinaga K

更新日期：2018-07-01 00:00:00

abstract：:Fibroadenoma of the breast is a common benign disease, occurring mainly in females younger than 30 years of age. Infant fibroadenoma is extremely rare. Here, we report on a 16-month-old female with a 6 month history of unilateral progressive breast enlargement. Upon clinical evaluation, a palpable mass was observed in...

journal_title：Japanese journal of clinical oncology

authors： Shi A,Li S,Xu N,Nie G,Li X,Zhang T,Fan Z

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the prognostic importance of the sequencing of radiation therapy and chemotherapy after mastectomy in high-risk premenopausal women with breast cancer in addition to other known prognostic factors in the literature. METHODS:In this retrospective study, 176 premenopau...

journal_title：Japanese journal of clinical oncology

authors： Cakir S,Gursel B,Meydan D,Yildiz L

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:It is difficult to reproduce a brachytherapy measurement because of changes in the rectal shape during inter-fraction. We constructed a multi-purpose brachytherapy phantom (MPBP) and reproduced the same conditions found in actual therapy. We further attempted to apply the measured optimal dose to reduce rectal ...

journal_title：Japanese journal of clinical oncology

authors： Huh H,Kim W,Loh JJ,Lee S,Kim CY,Lee S,Shin D,Shin D,Cho S,Jang J,Lim S,Cho KH,Kwon S,Kim S

更新日期：2007-05-01 00:00:00

abstract：:A rare case of adult T-cell leukemia/lymphoma with a giant exophytic gastric tumor invading the anterior abdominal wall is presented. The patient was a 52-year-old woman, who had a history of strongyloidiasis. Although the patient was serologically positive for HTLV-I antibody, there were no lymphoma cells in the peri...

journal_title：Japanese journal of clinical oncology

authors： Hiroyasu S,Shiraishi M,Shimabukuro M,Kusano T,Muto Y

更新日期：1996-10-01 00:00:00

abstract：:The present report describes two cases of renal cell carcinoma extending into the vena cava and the right atrium. The treatment was total nephrectomy and tumor thrombectomy, utilizing extracorporeal circulation. The aggressive surgical management of this progressive malignant disease is discussed. ...

journal_title：Japanese journal of clinical oncology

authors： Cho M,Ozono S,Takashima K,Moriya A,Hirao Y,Okajima E,Taniguchi S,Niwaya K,Kawachi K,Kitamura S

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:There have been few reports of sarcoid reaction in the regional lymph nodes associated with lung cancer. The purpose of this study was to analyze the surgical results of lung cancer with sarcoid reaction. METHODS:Of 1733 lung cancer patients undergoing surgical treatment in our institute from 1990 to 2004, ...

journal_title：Japanese journal of clinical oncology

authors： Tomimaru Y,Higashiyama M,Okami J,Oda K,Takami K,Kodama K,Tsukamoto Y

更新日期：2007-02-01 00:00:00

abstract：:The relations between alcohol consumption and cancers of the breast, corpus uteri and ovary were investigated in a case-control study involving 1,740 cases of breast cancer, 239 cases of cancer of the corpus uteri, 417 cases of ovarian cancer and 8,920 controls with other cancer sites identified from the Aichi Cancer ...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Tominaga S,Terao C

更新日期：1989-09-01 00:00:00

abstract：:A post hoc analysis of interim results from PREVAIL, a Phase III, double-blind, placebo-controlled trial of men with metastatic castration-resistant prostate cancer, demonstrated that the treatment effects, safety and pharmacokinetics of enzalutamide in Japanese patients were generally consistent with those of the ove...

journal_title：Japanese journal of clinical oncology

authors： Kimura G,Ueda T

更新日期：2017-03-01 00:00:00

abstract：:The use of lymphokine activated killer (LAK) cells for adoptive transfer therapy has been reported from number of clinical trials. To our knowledge, however, there has been no report concerning the cell cycle progression of LAK cells. Thus, for the present study we have attempted to examine the LAK cell cycle either b...

journal_title：Japanese journal of clinical oncology

authors： Watanabe R,Tanaka N,Naomoto Y,Moreira LF,Orita K

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Benefits of chemotherapy have generally been modest in gastric cancer, although those regimens developed more recently have produced higher response rates. Paclitaxel plus cisplatin is one such regimen and divided administration of paclitaxel has been suggested to be associated with lower neurological and he...

journal_title：Japanese journal of clinical oncology

authors： Kim YH,Yamaguchi K,Bang YJ,Takiuchi H,Kang WK,Sato A,Kang YK,Sakamoto J,Abe C,Sakata Y

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:There have been no previous studies about consultation of the bereaved who have lost a loved one to cancer and ask for medical help. The aim of this study was to investigate their basic characteristics and their psychiatric disorders. METHODS:A retrospective study using clinical and background data obtained ...

journal_title：Japanese journal of clinical oncology

authors： Ishida M,Onishi H,Wada M,Tada Y,Ito H,Narabayashi M,Sasaki Y,Nomura S,Uchitomi Y

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Colorectal cancer is one of the most common carcinomas observed in humans. Recently we have reported that increased oxidative stress is associated with human colorectal cancer. There are few and controversial studies on the clinical relevance of the expression of heat shock protein 70 (HSP 70), a member of t...

journal_title：Japanese journal of clinical oncology

authors： Ozdemirler Erata G,Kanbağli O,Durlanik O,Bulut T,Toker G,Uysal M

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to identify clinicopathological variables associated with the clinical outcomes of patients with lymph node metastasis-positive urothelial bladder carcinoma after radical cystectomy. METHODS:Forty-six patients who underwent radical cystectomy without preoperative chemotherapy and ha...

journal_title：Japanese journal of clinical oncology

authors： Nakagawa T,Kanai Y,Nakanishi H,Komiyama M,Fujimoto H

更新日期：2012-11-01 00:00:00

abstract：:A simple and effective method for concentrating sputum in the preparation of smears for cytodiagnosis of lung cancer was developed. The procedure, which utilizes a fixative consisting of 2,3-dihydroxy-1,4-dithiol-butane, 3,5-ditert-butyl-4-hydroxy-toluene, polyoxyethylene-cetyl-ether, polyethylene glycol 1540, and eth...

journal_title：Japanese journal of clinical oncology

authors： Yamagishi K,Koketsu H,Tajima M,Suemasu K

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation is the treatment of choice in young patients with severe aplastic anemia. The main causes of failure after this procedure are graft versus host disease, infections and graft failure, often exacerbated by large numbers of transfusions and prolonged disease du...

journal_title：Japanese journal of clinical oncology

authors： Rzepecki P,Sarosiek T,Szczylik C

更新日期：2006-01-01 00:00:00

abstract：:Carcinoid tumors located in the minor duodenal papilla are extremely rare, with only a few cases reported in the literature. Herein, we report the case of a 71-year-old man with a 12-mm carcinoid tumor at the minor duodenal papilla with lymph node metastases. Multidetector-row computed tomography with contrast enhance...

journal_title：Japanese journal of clinical oncology

authors： Fukami Y,Kurumiya Y,Mizuno K,Sekoguchi E,Kobayashi S,Ito A,Tomida A,Onishi S,Shirotsuki R,Okubo K,Narita M

更新日期：2013-01-01 00:00:00

abstract：:The rise in the incidence of lung cancer has been associated with shifts in histologic distribution. A study was conducted to investigate changes in the cell type distribution in lung cancer in relation to age, sex, and smoking history, based on a retrospective analysis of 10,910 proven cases of lung cancer at the Vet...

journal_title：Japanese journal of clinical oncology

authors： Perng DW,Perng RP,Kuo BI,Chiang SC

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:This retrospective study aimed to evaluate the efficacy of a 3.6-mg dose of pegfilgrastim for primary prophylaxis in Japanese breast cancer patients receiving dose-dense chemotherapy. METHODS:Patients treated with adjuvant or neoadjuvant chemotherapy for early-stage breast cancer at the Tokyo-West Tokushuka...

journal_title：Japanese journal of clinical oncology

authors： Mizuno Y,Fuchikami H,Takeda N,Iwai M,Sato K

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The outcomes of patients with localized or locally advanced prostate cancer treated with external-beam radiotherapy are not well known in Japan. METHODS:Thirty-four institutions combined data on 679 patients with localized or locally advanced prostate cancer treated with a total dose >/=60 Gy between 1995 a...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Mizowaki T,Imada H,Karasawa K,Uno T,Onishi H,Nihei K,Sasaki S,Ogura M,Akimoto T

更新日期：2008-03-01 00:00:00

abstract：:The proband was a 32-year-old man with sparse type of familial adenomatous polyposis with fundic gland and duodenal polyps and congenital hypertrophy of the retinal pigment epithelium without osteoma, dental abnormalities and desmoid tumors. Direct DNA sequencing did not detect germline mutations in any APC exon. Howe...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi T,Koizumi K,Arai M,Tamura K,Iijima T,Horiguchi S,Miyaki M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:This study was performed to review retrospectively the clinical course of chronic rectal bleeding as a complication of external beam radiation therapy for localized prostate cancer and to analyze the relationship between technical parameters of radiation therapy and the complications. METHODS:Seventy-one pa...

journal_title：Japanese journal of clinical oncology

authors： Kitamura K,Shirato H,Suzuki K,Shinohara N,Demura T,Harabayashi T,Nishioka T,Kagei K,Takayama N,Shinno Y,Kawakura K,Koyanagi T,Miyasaka K

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Inconsistency in the prevalence of infection by human papillomavirus (HPV) in lung cancer patients was found between different countries with racial and geographic variations. Our previous reports have indicated that a high-risk HPV 16/18 DNA was frequently detected in Chinese lung cancer patients living in ...

journal_title：Japanese journal of clinical oncology

authors： Fei Y,Yang J,Hsieh WC,Wu JY,Wu TC,Goan YG,Lee H,Cheng YW

更新日期：2006-05-01 00:00:00

abstract：:A randomized phase III trial was initiated in Japan in August 2019 to confirm the superiority of preoperative chemoradiotherapy followed by surgery plus adjuvant chemotherapy compared to the standard treatment, i.e. surgery plus adjuvant chemotherapy, for locally recurrent rectal cancer in local relapse-free survival....

journal_title：Japanese journal of clinical oncology

authors： Kadota T,Tsukada Y,Ito M,Katayama H,Mizusawa J,Nakamura N,Ito Y,Bando H,Ando M,Onaya H,Fukuda H,Kanemitsu Y

更新日期：2020-08-04 00:00:00