A large deletion of chromosome 5q22.1-22.2 associated with sparse type of familial adenomatous polyposis: report of a case.

abstract：OBJECTIVE:To evaluate the correlations between the changes in the quality-of-life scores and the dose-volume histogram parameters in patients receiving high-dose-rate brachytherapy combined with hypofractionated external beam radiation therapy for localized prostate cancer. METHODS:Among the patients who were treated ...

journal_title：Japanese journal of clinical oncology

authors： Hashimoto Y,Akimoto T,Iizuka J,Tanabe K,Mitsuhashi N

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Most cancer patients become increasingly anxious toward the end of their life. The objective of this study was to identify predictors of increased opioid dosage in the last week of a terminal cancer patient's life. METHODS:We retrospectively reviewed charts of patients who died in our palliative care unit. W...

journal_title：Japanese journal of clinical oncology

authors： Miura T,Matsumoto Y,Motonaga S,Hasuo H,Abe K,Kinoshita H

更新日期：2014-11-01 00:00:00

abstract：:There have been no reports describing acute exacerbations of idiopathic pulmonary fibrosis after particle radiotherapy for non-small cell lung cancer. The present study describes the case of a 76-year-old Japanese man with squamous cell carcinoma of the lung that relapsed in the left upper lobe 1 year after right uppe...

journal_title：Japanese journal of clinical oncology

authors： Nagano T,Kotani Y,Fujii O,Demizu Y,Niwa Y,Ohno Y,Nishio W,Itoh T,Murakami M,Nishimura Y

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare tumor usually diagnosed at an advanced stage on invasion of or adherence to adjacent organs. We report surgical outcome of stage III and IV ACCs. METHODS:ACCs from seven patients at clinical stage II (n = 1), III (n = 4), or IV (n = 2) were resected. Combined resecti...

journal_title：Japanese journal of clinical oncology

authors： Ohwada S,Izumi M,Kawate S,Hamada K,Toya H,Togo N,Horiguchi J,Koibuchi Y,Takahashi T,Yamada M

更新日期：2007-02-01 00:00:00

abstract：:Mucin-producing carcinoma of the thyroid is rare and its histogenesis has been debated. The first case was reported by Diaz-Perez et al. (1976). We herein report the sixth case of mucin-producing carcinoma of the thyroid which was discovered in a 72-year-old Japanese woman. This patient was admitted with a 10-year his...

journal_title：Japanese journal of clinical oncology

authors： Harada T,Shimaoka K,Hiratsuka M,Hirokawa M,Tsukayama C

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Programmed death-ligand 1 is an immune modulator that promotes immunosuppression by binding to programmed death-1 of T-lymphocytes. Whereas programmed death-ligand 1 expression has been shown to be associated with the clinical response to anti-programmed death-ligand 1 antibody, the association of tumor prog...

journal_title：Japanese journal of clinical oncology

authors： Inamura K,Yokouchi Y,Sakakibara R,Kobayashi M,Subat S,Ninomiya H,Nagano H,Nomura K,Okumura S,Ishikawa Y

更新日期：2016-10-01 00:00:00

abstract：:A randomized phase III trial was initiated in Japan in August 2019 to confirm the superiority of preoperative chemoradiotherapy followed by surgery plus adjuvant chemotherapy compared to the standard treatment, i.e. surgery plus adjuvant chemotherapy, for locally recurrent rectal cancer in local relapse-free survival....

journal_title：Japanese journal of clinical oncology

authors： Kadota T,Tsukada Y,Ito M,Katayama H,Mizusawa J,Nakamura N,Ito Y,Bando H,Ando M,Onaya H,Fukuda H,Kanemitsu Y

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVE:Anatomical segmentectomy has the potential to replace lobectomy as the standard procedure for early stage non-small cell lung cancer. We investigated the safety and feasibility of robotic anatomical segmentectomy for non-small cell lung cancer. METHODS:Overall 20 patients underwent robotic anatomical segment...

journal_title：Japanese journal of clinical oncology

authors： Kagimoto A,Tsutani Y,Izaki Y,Handa Y,Mimae T,Miyata Y,Okada M

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:We investigated the expression of PyNPase both in cancer cells and in stroma cells to clarify the correlation between PyNPase expression and the prognosis of patients with colorectal cancer. METHODS:Using immunohistochemical staining with an anti-PyNPase antibody, the PyNPase expression in tissues from 114 ...

journal_title：Japanese journal of clinical oncology

authors： Osanai T,Ichikawa W,Takagi Y,Uetake H,Nihei Z,Sugihara K

更新日期：2001-10-01 00:00:00

abstract：:We encountered a patient with hepatocellular carcinoma (HCC) with peritoneal dissemination and needle tract implantation, both of which were strongly suspected to have been caused by percutaneous needle biopsy. The patient was a 65-year-old man. Partial hepatectomy of subsegment VI had been performed following the dia...

journal_title：Japanese journal of clinical oncology

authors： Takahashi H,Konishi M,Nakagohri T,Inoue K,Takahashi S,Tanizawa Y,Monden M,Kinoshita T

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To assess the resectability rate of patients with initially unresectable liver-only metastases from colorectal cancer (CRC) after treatment with irinotecan/capecitabine. METHODS:Patients received irinotecan (240 mg/m(2)) as a 30 min intravenous infusion on day 1 and capecitabine (1000 mg/m(2)) orally bid for...

journal_title：Japanese journal of clinical oncology

authors： Zhao R,Zhu J,Ji X,Cai J,Wan F,Li Q,Zhong B,Tucker S,Wang D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:CD10 is a cell surface metalloproteinase expressed by a variety of normal cell types, including lymphoid precursor cells, germinal center B lymphocytes and some epithelial cells. Although accumulating data indicate that CD10 expression by stromal cells is involved in colorectal carcinogenesis and it is a nov...

journal_title：Japanese journal of clinical oncology

authors： Huang WB,Zhou XJ,Chen JY,Zhang LH,Meng K,Ma HH,Lu ZF

更新日期：2005-05-01 00:00:00

abstract：:Cancer is already a well-recognized global phenomenon. The traditional approaches to cancer therapy have been surgery, radiotherapy and chemotherapy. These modalities have shown considerable promise and presently form cornerstones of management of most malignancies. However, these conventional approaches have associat...

journal_title：Japanese journal of clinical oncology

authors： Munshi A,Ni LH,Tiwana MS

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:We performed a retrospective review of clinical T1a renal cell carcinoma patients treated in our institution. The clinicopathological findings and patients' prognoses were analyzed according to tumor size, and risk factors for tumor recurrence were elucidated. METHODS:A total of 140 cases of sporadic renal c...

journal_title：Japanese journal of clinical oncology

authors： Kitagawa Y,Nakashima K,Shima T,Izumi K,Narimoto K,Miwa S,Miyagi T,Maeda Y,Kadono Y,Konaka H,Mizokami A,Namiki M

更新日期：2011-05-01 00:00:00

abstract：BACKGROUNDS:Mutations in the isocitrate dehydrogenase (IDH)1 gene are favourable prognostic factors in newly diagnosed diffuse gliomas, whereas it remains controversial in the recurrent glioblastoma setting. METHODS:A total of 171 patients with newly diagnosed glioblastoma, either 'primary' glioblastoma or 'secondary'...

journal_title：Japanese journal of clinical oncology

authors： Tabei Y,Kobayashi K,Saito K,Shimizu S,Suzuki K,Sasaki N,Shiokawa Y,Nagane M

更新日期：2021-01-01 00:00:00

abstract：:One hundred and one cases of lung cancer were immunohistochemically studied for stainability with Leu-7 (anti-myelin fiber associated glycoprotein) and OKT-9 (anti-transferrin receptor) monoclonal antibodies. All small cell carcinomas and carcinoid tumors were positively stained by Leu-7, and 22 of 41 differentiated a...

journal_title：Japanese journal of clinical oncology

authors： Sato Y,Watanabe S,Kodama T,Goto M,Shimosato Y

更新日期：1985-09-01 00:00:00

abstract：:The PRECIOUS study (UMIN000018202) is being conducted as a multicenter, randomized, open-label Phase III study to determine if retreatment with pertuzumab is more effective than conventional treatment in HER2-positive locally advanced (LA)/metastatic breast cancer (MBC) patients previously treated with pertuzumab, tra...

journal_title：Japanese journal of clinical oncology

authors： Yamamoto Y,Iwata H,Ueno T,Taira N,Kashiwaba M,Takahashi M,Tada H,Tsugawa K,Toyama T,Niikura N,Hara F,Fujisawa T,Yoshinami T,Saji S,Takano T,Masuda N,Morita S,Toi M,Ohno S

更新日期：2018-09-01 00:00:00

abstract：:MVP-CAB chemotherapy (methotrexate, vincristine, cisplatin, cyclophosphamide, adriamycin and bleomycin) was administered to 28 patients with high grade, locally-invasive or regional lymph node-involved urothelial cancer as an adjuvant therapy after radical surgery. The median follow-up period of all the evaluated pati...

journal_title：Japanese journal of clinical oncology

authors： Gohji K,Higuchi A,Maruyama S,Minayoshi K,Fujii A,Itoh N,Hasunuma Y,Tanaka H,Izumi T

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To determine the extent of informed decision-making and treatment preference of Korean patients receiving palliative chemotherapy. METHODS:We assessed 138 patients (median age: 58 years; 73% male) with advanced cancer who had received at least one cycle of chemotherapy. General demographic information, the e...

journal_title：Japanese journal of clinical oncology

authors： Kim MK,Lee JL,Hyun MS,Do YR,Song HS,Kim JG,Bae SH,Ryoo HM,Park KU,Lee KH

更新日期：2008-01-01 00:00:00

abstract：:The Radiation Therapy Study Group (RTSG) of the Japan Clinical Oncology Group (JCOG) was established in 2003. The missions of this group are to develop new standards of care with innovative, advanced technology radiation therapy, both for single- and multi-modality cancer treatment, and to improve radiation therapy qu...

journal_title：Japanese journal of clinical oncology

authors： Ishikura S,Ito Y,Hiraoka M

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:This retrospective study analyzed the oncological and treatment outcomes of the patients with T1-T2N0 glottic cancer, who were treated with radiotherapy as initial treatment and salvaged by conservative surgery for radiation failure. METHODS:Between May 1999 and December 2010, 115 patients with glottic laryn...

journal_title：Japanese journal of clinical oncology

authors： Harada A,Sasaki R,Miyawaki D,Yoshida K,Nishimura H,Ejima Y,Kitajima K,Saito M,Otsuki N,Nibu K

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:To evaluate computed tomography findings and assess the clinical course of patients with pulmonary epithelioid hemangioendothelioma. METHODS:Patients diagnosed with pulmonary epithelioid hemangioendothelioma at our institution between 2000 and 2019 were retrospectively analyzed. Patients with pleural involv...

journal_title：Japanese journal of clinical oncology

authors： Onishi Y,Kusumoto M,Goto Y,Kaku S,Motoi N

更新日期：2020-09-28 00:00:00

abstract：:Age-adjusted incidence rates for malignant lymphomas in eastern Asian countries except for the Kyushu district of Japan are lower than those in northern European, North and South American and Oceanian countries. Particularly, the incidence rates for Hodgkin's disease and follicular lymphoma are remarkably low in easte...

journal_title：Japanese journal of clinical oncology

authors： Tajima K,Tominaga S,Suchi T

更新日期：1983-09-01 00:00:00

abstract：Background:Leiomyosarcoma (LMS) is one of most aggressive mesenchymal malignancies that differentiate towards smooth muscle. The clinical outcome of LMS patients is poor; as such, there is an urgent need for novel therapeutic approaches. Experimental models such as patient-derived cell lines are invaluable tools for pr...

journal_title：Japanese journal of clinical oncology

authors： Sakumoto M,Takahashi M,Oyama R,Takai Y,Kito F,Shiozawa K,Qiao Z,Yoshida A,Endo M,Kawai A,Kondo T

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as advanced and inoperable due to the lack of effective biomarkers and poor sensitivity of clinical diagnosis. Here, we aimed to identify the genomic profile of CCA and provided molecular evidence for further biomarker development. ME...

journal_title：Japanese journal of clinical oncology

authors： Jiang G,Zhang W,Wang T,Ding S,Shi X,Zhang S,Shi W,Liu A,Zheng S

更新日期：2020-09-28 00:00:00

abstract：BACKGROUND:Patterns of cancer incidence and radiotherapy use are similar in Korea and Japan, with differences in radiotherapy infrastructure. METHODS:The authors surveyed the megavoltage machines in 91 radiotherapy centers in Korea and published data in Japan. The number of megavoltage machines per center was used as ...

journal_title：Japanese journal of clinical oncology

authors： Huh SJ,Nishimura T,Park W,Nakamura K

更新日期：2019-12-18 00:00:00

abstract：:A double blind study to compare the efficacy of oral UFT (400 mg Tegafur (FT) plus 896 mg uracil/day) with that of oral FT (800 mg/day) on advanced breast cancer was performed between November, 1986, and November, 1989. Sixty patients were registered for the trial and fifty-six cases were evaluated (28 for UFT and 28 ...

journal_title：Japanese journal of clinical oncology

authors： Tashiro H,Nomura Y,Ohsaki A

更新日期：1994-08-01 00:00:00

abstract：:Pure red cell aplasia (PRCA) rarely occurs in non-thymic lymphoproliferative disorders. The present article describes a patient with non-Hodgkin's lymphoma (follicular, mixed type), who concurrently developed PRCA and warm type autoimmune hemolytic anemia during the clinical course. The PRCA and hemolytic anemia were ...

journal_title：Japanese journal of clinical oncology

authors： Suzuki A,Takahashi T,Taniguchi A,Kotake C,Seo T,Toda T,Kobayashi K,Tsukamoto N,Fukumoto M

更新日期：1991-10-01 00:00:00

abstract：Background:Unexpected multiple primary carcinomas (MPCs) that develop in patients with head and neck carcinomas complicate approaches to their management. We therefore investigated the clinical factors associated with survival outcomes after the treatment of MPCs. Methods:We performed a retrospective review of records...

journal_title：Japanese journal of clinical oncology

authors： Hosokawa S,Takahashi G,Okamura J,Imai A,Mochizuki D,Takizawa Y,Yamatodani T,Misawa K,Mineta H

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To clarify the clinical outcomes of stereotactic body radiotherapy for colorectal cancer-derived bone metastases and identify factors predicting treatment failure. METHODS:Patients treated with stereotactic body radiotherapy for bone metastases from colorectal cancer between September 2013 and June 2019 were...

journal_title：Japanese journal of clinical oncology

authors： Ito K,Yamaguchi T,Ogawa H,Nakajima Y,Karasawa K

更新日期：2020-12-16 00:00:00