Establishment and proteomic characterization of NCC-LMS1-C1, a novel cell line of primary leiomyosarcoma of the bone.

abstract：:BAT-25 is a DNA marker, intragenic to the c-kit protooncogene, assigned to 4q12, containing a polythymine tract, mostly repeats of 25 poly(T) (T25). The BAT-25 locus is frequently used in the analysis of microsatellite instability (MSI) in cancer tissues. The number of poly(T) repeats at BAT-25 is reported to be quasi...

journal_title：Japanese journal of clinical oncology

authors： Ichikawa A,Sugano K,Fujita S

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:We conducted a dose-finding and feasibility study in which we administered a fixed dose 3-h infusion of paclitaxel and an escalating dose of cisplatin in Japanese patients with advanced non-small cell lung cancer. METHODS:Chemotherapy consisted of fixed dose (210 mg/m(2)) paclitaxel given over 3 h on day 1 ...

journal_title：Japanese journal of clinical oncology

authors： Watanabe H,Yamamoto N,Tamura T,Shimoyama T,Hotta K,Inoue A,Sawada M,Akiyama Y,Kusaba H,Nokihara H,Sekine I,Kunitoh H,Ohe Y,Kodama T,Saijo N

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Angiogenesis is required for growth and metastasis of colorectal cancer (CRC), and several positive regulators of tumor angiogenesis have been identified. Cyclooxygenase-2 (COX-2), known to be elevated in several human cancers, regulates angiogenesis by inducing angiogenic factors. The aim of this study was ...

journal_title：Japanese journal of clinical oncology

authors： Nakamoto RH,Uetake H,Iida S,Kolev YV,Soumaoro LT,Takagi Y,Yasuno M,Sugihara K

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:This study was performed to review retrospectively the clinical course of chronic rectal bleeding as a complication of external beam radiation therapy for localized prostate cancer and to analyze the relationship between technical parameters of radiation therapy and the complications. METHODS:Seventy-one pa...

journal_title：Japanese journal of clinical oncology

authors： Kitamura K,Shirato H,Suzuki K,Shinohara N,Demura T,Harabayashi T,Nishioka T,Kagei K,Takayama N,Shinno Y,Kawakura K,Koyanagi T,Miyasaka K

更新日期：2000-05-01 00:00:00

abstract：:Cancer originating in the biliary tract can be classified as bile duct cancer (cholangiocarcinoma), gallbladder cancer, or ampullary cancer. Bile duct cancer is further divided to intrahepatic, perihilar and distal bile duct subtypes according to the anatomical location of the tumor. The biological characteristics of ...

journal_title：Japanese journal of clinical oncology

authors： Nara S,Esaki M,Ban D,Takamoto T,Shimada K,Ioka T,Okusaka T,Ishii H,Furuse J

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare tumor usually diagnosed at an advanced stage on invasion of or adherence to adjacent organs. We report surgical outcome of stage III and IV ACCs. METHODS:ACCs from seven patients at clinical stage II (n = 1), III (n = 4), or IV (n = 2) were resected. Combined resecti...

journal_title：Japanese journal of clinical oncology

authors： Ohwada S,Izumi M,Kawate S,Hamada K,Toya H,Togo N,Horiguchi J,Koibuchi Y,Takahashi T,Yamada M

更新日期：2007-02-01 00:00:00

abstract：:The development of PD-1 pathway inhibitors has dramatically altered the treatment of advanced/recurrent non-small-cell lung cancer patients. However, the prognostic significance of their ongoing usage is controversial, especially for patients who have not progressed for a period of time. If discontinuation has no nega...

journal_title：Japanese journal of clinical oncology

authors： Nomura S,Goto Y,Mizutani T,Kataoka T,Kawai S,Okuma Y,Murakami H,Tanaka K,Ohe Y

更新日期：2020-07-09 00:00:00

abstract：OBJECTIVE:Apocrine carcinoma, a subtype of invasive ductal carcinoma of the breast, expresses androgen receptor (AR), but often lacks estrogen receptor (ER) and progesterone receptor (PgR). In the present study, the author immunohistochemically defined apocrine-type carcinoma as ER-/PgR-/AR+ invasive ductal carcinoma a...

journal_title：Japanese journal of clinical oncology

authors： Tsutsumi Y

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:Trop-1/Ep-CAM modulates growth and survival of transformed cells, and it is highly expressed in most carcinomas including breast cancer. Only membranous staining is typically considered in evaluating Trop-1/epithelial cell adhesion molecule (Ep-CAM) expression in tumor cells. However, there is evidence of ret...

journal_title：Japanese journal of clinical oncology

authors： Alberti S,Ambrogi F,Boracchi P,Fornili M,Querzoli P,Pedriali M,La Sorda R,Lattanzio R,Tripaldi R,Piantelli M,Biganzoli E,Coradini D

更新日期：2012-12-01 00:00:00

abstract：:In order to study the characteristics of lung cancer in smokers and nonsmokers, clinico-epidemiological features of 943 lung cancer patients treated in the Aichi Cancer Center Hospital from 1964-77 were analyzed according to their smoking histories. About 70% of both male and female patients who smoked fell in Group I...

journal_title：Japanese journal of clinical oncology

authors： Shimizu H,Tominaga S,Nishimura M,Urata A

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Uracil-tegafur (UFT) has been reported to have broad antitumor activity in a variety of malignancies. However, its activity in biliary tract carcinoma has not been fully evaluated. The aim of this study was to evaluate the antitumor activity and toxicity of UFT in chemotherapy-naive patients with advanced bi...

journal_title：Japanese journal of clinical oncology

authors： Ikeda M,Okusaka T,Ueno H,Morizane C,Furuse J,Ishii H

更新日期：2005-08-01 00:00:00

abstract：:A clinical review with analysis of prognostic factors, including the impact of the initial management modality, was conducted on 137 patients with superior vena cava syndrome (SVCS) seen at the Veterans General Hospital-Taipei between 1989 and 1993. Malignant diseases account for most of the SVCS in our Chinese patien...

journal_title：Japanese journal of clinical oncology

authors： Chen YM,Yang S,Perng RP,Tsai CM

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To identify predictors of biochemical recurrence (BCR) after radical prostatectomy with or without standard pelvic lymphadenectomy in Korean men with high-risk prostate cancer. METHODS:The clinical and pathologic data of 199 patients with high-risk features were reviewed retrospectively. High-risk features w...

journal_title：Japanese journal of clinical oncology

authors： Ku JH,Jeong CW,Park YH,Cho MC,Kwak C,Kim HH

更新日期：2011-05-01 00:00:00

abstract：:An in vitro monolayer model for cancer invasion was developed, comprising cultured layers of human pleura-derived mesothelial cells (PM cells). The cells were isolated from normal human pleura at autopsy and cultured in RPMI-1640 supplemented with 10% fetal calf serum; they were polygonal in shape, forming a pavement-...

journal_title：Japanese journal of clinical oncology

authors： Horai T,Imamura F,Nakae T,Nakamura S,Mukai M,Shinkai K,Higashino K,Akedo H

更新日期：1992-04-01 00:00:00

abstract：:To elucidate the relationship between the clinical features and pathologic findings of primary pulmonary lymphoma, we reviewed 24 patients with this disease. The pulmonary lymphomas were divided into four groups: (1) B-cell lymphoma composed of small to medium-sized lymphoid cells (19 cases); (2) B-cell lymphoma compo...

journal_title：Japanese journal of clinical oncology

authors： Tamura A,Komatsu H,Yanai N,Homma J,Nagase A,Nemoto E,Hirai T,Hashizume T,Kawata K,Ishikawa S

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Regular endoscopic surveillance for Lynch syndrome is reported to reduce colorectal cancer (CRC)-related mortality. However, the appropriate surveillance intervals are still unclear. We evaluated the adequacy of annual colonoscopy and investigated the differences in tumor occurrence rates between individual ...

journal_title：Japanese journal of clinical oncology

authors： Taniguchi F,Tanakaya K,Sugano K,Akagi K,Ishida H,Nagahisa S,Nishimura S,Une Y,Kimura Y,Watanabe M,Utsumi M,Aoki H

更新日期：2020-06-10 00:00:00

abstract：BACKGROUND:In Japan, concurrent chemoradiotherapy is the standard treatment for unresectable esophageal cancer. The optimal combination of chemotherapeutic agents and radiotherapy dose remains controversial. The present study consists of a phase II trial of a cisplatin (CDDP)/5-fluorouracil (5-FU) infusion with concurr...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Ando N,Yamamoto S,Ide H,Shinoda M

更新日期：2004-10-01 00:00:00

abstract：:Recent studies have suggested that glutathione S-transferase pi (GST-pi) may play a role in determining tumor sensitivities to cytotoxic drugs. In order to better understand the role of this enzyme in chemo- and/or radioresistance of lung cancer cells, we examined whether introduction of GST-pi cDNA into a chemo- and ...

journal_title：Japanese journal of clinical oncology

authors： Miyara H,Hida T,Nishida K,Takahashi T,Sugiura T,Ariyoshi Y,Morishita M,Takahashi T,Ueda R

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:The CpG island methylator phenotype is strongly associated with poor survival in neuroblastomas. Neuroblastomas with the CpG island methylator phenotype include almost all neuroblastomas with MYCN amplification, and, even among neuroblastomas without MYCN amplification, have worse prognosis. At the same time,...

journal_title：Japanese journal of clinical oncology

authors： Asada K,Watanabe N,Nakamura Y,Ohira M,Westermann F,Schwab M,Nakagawara A,Ushijima T

更新日期：2013-06-01 00:00:00

abstract：:One hundred and one cases of lung cancer were immunohistochemically studied for stainability with Leu-7 (anti-myelin fiber associated glycoprotein) and OKT-9 (anti-transferrin receptor) monoclonal antibodies. All small cell carcinomas and carcinoid tumors were positively stained by Leu-7, and 22 of 41 differentiated a...

journal_title：Japanese journal of clinical oncology

authors： Sato Y,Watanabe S,Kodama T,Goto M,Shimosato Y

更新日期：1985-09-01 00:00:00

abstract：:Squamous cell carcinoma of the head and neck is characterized by an immunosuppressive environment and evades immune responses through multiple resistance mechanisms. A breakthrough in cancer immunotherapy employing immune checkpoint inhibitors has evolved into a number of clinical trials with antibodies against progra...

journal_title：Japanese journal of clinical oncology

authors： Yokota T,Homma A,Kiyota N,Tahara M,Hanai N,Asakage T,Matsuura K,Ogawa T,Saito Y,Sano D,Kodaira T,Motegi A,Yasuda K,Takahashi S,Tanaka K,Onoe T,Okano S,Imamura Y,Ariizumi Y,Hayashi R,Japan Clinical Oncology Group (

更新日期：2020-09-28 00:00:00

abstract：:We report on an inflammatory pseudotumor of the spleen. A 72-year-old woman visited our hospital complaining of nausea. Physical examination and laboratory investigations were unremarkable. Ultrasonography, computed tomography, magnetic resonance imaging and angiography showed a hypovascular splenic mass measuring abo...

journal_title：Japanese journal of clinical oncology

authors： Noguchi H,Kondo H,Kondo M,Shiraiwa M,Monobe Y

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Recent studies reported that hospital procedure volume (i.e. volume of patients per hospital receiving a particular treatment)was directly proportional to cancer survival; however the degree of association might be different according to the primary tumor site, extent of disease and year of diagnosis. We per...

journal_title：Japanese journal of clinical oncology

authors： Ioka A,Tsukuma H,Ajiki W,Oshima A

更新日期：2007-07-01 00:00:00

abstract：:Inguinal lymph node metastasis from adenocarcinoma arising at a colostomy site is extremely rare, and the significance of surgical resection for metastatic inguinal lymph nodes has not been established. An 82-year-old woman who had undergone abdominoperineal resection 27 years earlier was admitted to our hospital comp...

journal_title：Japanese journal of clinical oncology

authors： Iwamoto M,Kawada K,Hida K,Hasegawa S,Sakai Y

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:We sought to investigate general health status and late effects among adolescent and young adult survivors of childhood cancer. METHODS:We conducted a cross-sectional survey, using self-rated questionnaires on current and past health problems. Questionnaires were provided to childhood cancer survivors, a com...

journal_title：Japanese journal of clinical oncology

authors： Ozono S,Ishida Y,Honda M,Okamura J,Asami K,Maeda N,Sakamoto N,Inada H,Iwai T,Kamibeppu K,Kakee N,Horibe K

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Although there have been extensive studies to determine risk factors affecting survival after resection for hepatocellular carcinoma (HCC), we still do not know which patients can survive disease free after curative resection. This study was undertaken to determine independent risk factors affecting the leng...

journal_title：Japanese journal of clinical oncology

authors： Takata M,Yamanaka N,Tanaka T,Yamanaka J,Maeda S,Okamoto E,Yasojima H,Uematsu K,Watanabe H,Uragari Y

更新日期：2000-02-01 00:00:00

abstract：:This study is conducted to evaluate the efficacy and safety of preoperative exercise in patients with T1N0/T1N1/T2N0 gastric cancer and metabolic syndrome, which has emerged as a global health care issue. The primary endpoint is an incidence of perioperative complications and the secondary endpoints are weight change,...

journal_title：Japanese journal of clinical oncology

authors： Cho H,Tsuburaya A,Sakamoto J,Morita S,Oba K,Yoshikawa T,Miyajima N,Adjuvant Exercise for General Elective Surgery (AEGES) Study Group.

更新日期：2008-01-01 00:00:00

abstract：:Pelvic lymphadenectomy is generally performed to treat early-stage cervical cancer, and pelvic ± para-aortic lymphadenectomy is performed in patients with endometrial cancer confined to the uterus. However, systematic lymphadenectomy is frequently associated with sequelae including lymphocele, lymphedema and celluliti...

journal_title：Japanese journal of clinical oncology

authors： Niikura H,Tsuji K,Tokunaga H,Shimada M,Ishikawa M,Yaegashi N

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Until 1998 in Japan, very few institutions were treating prostate cancer solely with radiotherapy (RT) >70 Gy and most were using < or =65 Gy in combination with hormone therapy. The present study reports the long-term results of RT combined with hormone therapy for localized and locally advanced prostate ca...

journal_title：Japanese journal of clinical oncology

authors： Hashine K,Numata K,Azuma K,Sumiyoshi Y,Kataoka M

更新日期：2005-11-01 00:00:00

abstract：:The concepts of lifetime and age-conditional probabilities of developing and dying of cancer are introduced as indexes to understand the risk of cancer. In this paper, we estimated the lifetime and age-conditional probabilities of developing and dying of cancer in 2001 and 2005, respectively, in Japan. It is estimated...

journal_title：Japanese journal of clinical oncology

authors： Kamo K,Katanoda K,Matsuda T,Marugame T,Ajiki W,Sobue T

更新日期：2008-08-01 00:00:00