当前位置： SCI文献检索 > JAPANESE JOURNAL OF CLINICAL ONCOLOGY期刊下所有文献 > General health status and late effects among adolescent and young adult survivors of childhood cancer in Japan.

General health status and late effects among adolescent and young adult survivors of childhood cancer in Japan.

Abstract：

OBJECTIVE:We sought to investigate general health status and late effects among adolescent and young adult survivors of childhood cancer. METHODS:We conducted a cross-sectional survey, using self-rated questionnaires on current and past health problems. Questionnaires were provided to childhood cancer survivors, a comparison group of siblings and a general population control group that was recruited online. χ(2) tests were used to compare responses to the 72 survey items. RESULTS:The final sample included 185 childhood cancer survivors (72% response rate), 72 siblings and 1000 general population controls. In the childhood cancer survivors group, the median age of diagnosis was 8 years and the median age at survey was 23 years. According to the physicians' reports, 56% of the childhood cancer survivors experienced at least one late effect. In descending order of prevalence, the current symptoms in the childhood cancer survivors group were (i) impaired visual acuity (45%), (ii) dizziness (36%) and (iii) any allergy (34%). The three most common symptoms had similar prevalence rates in each of the groups. As compared with the control group, the following physical symptoms were significantly more common in the childhood cancer survivors group: mental retardation (odds ratio: 48.6, P < 0.01); cataract (odds ratio: 29.7); suspected infertility (odds ratio: 25.1); delayed puberty (odds ratio 24.9); growth hormone deficiency (odds ratio: 23.0); and other audiovisual, urinary, endocrine, infertility, cardiovascular, respiratory, gastrointestinal, spinal, extremity and neuromuscular problems. CONCLUSIONS:Many adolescent/young adult childhood cancer survivors could be suffering from ongoing late effects that stem from cancer and its treatment. Overall health monitoring for childhood cancer survivors can provide indispensable benefits.

journal_name

Jpn J Clin Oncol

journal_title

Japanese journal of clinical oncology

authors

Ozono S,Ishida Y,Honda M,Okamura J,Asami K,Maeda N,Sakamoto N,Inada H,Iwai T,Kamibeppu K,Kakee N,Horibe K

doi

10.1093/jjco/hyu102

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

932-40

issue

10

eissn

0368-2811

issn

1465-3621

pii

hyu102

journal_volume

44

pub_type

杂志文章

相关文献

JAPANESE JOURNAL OF CLINICAL ONCOLOGY文献大全
  • Hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannoma.

    abstract：OBJECTIVE:To retrospectively examine the outcomes of hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannomas. METHODS:Twenty-five patients with 26 vestibular schwannomas were treated with hypofractionated stereotactic radiation therapy using a CyberKnife. The vestibular sc...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyt082

    authors： Morimoto M,Yoshioka Y,Kotsuma T,Adachi K,Shiomi H,Suzuki O,Seo Y,Koizumi M,Kagawa N,Kinoshita M,Hashimoto N,Ogawa K

    更新日期：2013-08-01 00:00:00

  • A Phase 1 study evaluating AMG 337 in Asian patients with advanced solid tumors.

    abstract：:AMG 337, a selective small-molecule MET inhibitor, was evaluated in Asian patients with advanced solid tumors. Eligible patients orally self-administered AMG 337; the initial dose of 150 mg once daily (QD) was escalated to 300 mg QD (modified 3+3+3 design). Treatment continued until disease progression, intolerability...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyx067

    authors： Yasui H,Go N,Yang H,Amore BM,Jung AS,Doi T

    更新日期：2017-08-01 00:00:00

  • MicroRNAs in Cancer: the 22nd Hiroshima Cancer Seminar/the 4th Japanese Association for RNA Interference Joint International Symposium, 30 August 2012, Grand Prince Hotel Hiroshima.

    abstract：:The joint international symposium of the 22nd Hiroshima Cancer Seminar and the 4th Japanese Association for RNA Interference focused on a pivotal role of microRNAs in carcinogenesis, progression and therapy of human cancer. Mammalian immune regulator MCPIP1 (Zc3h12a) RNase acts as a novel suppressor of microRNA activi...

    journal_title：Japanese journal of clinical oncology

    pub_type：

    doi：10.1093/jjco/hyt037

    authors： Tahara H,Kay MA,Yasui W,Tahara E

    更新日期：2013-05-01 00:00:00

  • The sequencing of radiation therapy and chemotherapy after mastectomy in premenopausal women with breast cancer.

    abstract：OBJECTIVE:The purpose of this study was to evaluate the prognostic importance of the sequencing of radiation therapy and chemotherapy after mastectomy in high-risk premenopausal women with breast cancer in addition to other known prognostic factors in the literature. METHODS:In this retrospective study, 176 premenopau...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyg102

    authors： Cakir S,Gursel B,Meydan D,Yildiz L

    更新日期：2003-11-01 00:00:00

  • Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.

    abstract：:Eight cultured cell lines were established from human small cell lung cancers. Every cell line showed the morphological and biochemical characteristics of small cell cancer. Changes in cell characteristics were observed in many of these cell lines when culture conditions were changed: "oat cell type" changed to "inter...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：

    authors： Terasaki T,Shimosato Y,Nakajima T,Tsumuraya M,Morinaga S,Hirohashi S,Yamaguchi K,Kato K,Ichinose H,Nagatsu T

    更新日期：1986-09-01 00:00:00

  • Antitumor activity of D-mannosamine in vitro: cytotoxic effect produced by mannosamine in combination with free fatty acids on human leukemia T-cell lines.

    abstract：:Cytotoxic effects of mannosamine and free fatty acids on human malignant T-lymphoid cell lines derived from patients with T-cell leukemia were investigated. The combination of mannosamine and an unsaturated fatty acid (oleate or linoleate) produced more striking cytotoxic effects on malignant lymphoid cells than on no...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：

    authors： Onoda T,Morikawa S,Harada T,Morikawa K

    更新日期：1985-09-01 00:00:00

  • Physical activity and colorectal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population.

    abstract：OBJECTIVE:Higher levels of physical activity have been consistently associated with a decreased risk of colon cancer, but not rectal cancer, in Western populations. The present study systematically evaluated epidemiologic evidence on the association between physical activity and colorectal cancer risk among the Japanes...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章,评审

    doi：10.1093/jjco/hyr160

    authors： Pham NM,Mizoue T,Tanaka K,Tsuji I,Tamakoshi A,Matsuo K,Ito H,Wakai K,Nagata C,Sasazuki S,Inoue M,Tsugane S,Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

    更新日期：2012-01-01 00:00:00

  • Trends for the past 10 years and international comparisons of the structure of Korean radiation oncology.

    abstract：OBJECTIVE:Study aims include determination of nationwide structural characteristics of radiation oncology facilities, types of radiation therapy equipment, availability of human resources and trends and comparisons with previous surveys. METHODS:An annual nationwide survey was conducted to collect the statistics of in...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyq001

    authors： Ji YH,Jung H,Yang K,Cho CK,Yoo SY,Yoo HJ,Kim KB,Kim MS

    更新日期：2010-05-01 00:00:00

  • Different human papillomavirus 16/18 infection in Chinese non-small cell lung cancer patients living in Wuhan, China.

    abstract：BACKGROUND:Inconsistency in the prevalence of infection by human papillomavirus (HPV) in lung cancer patients was found between different countries with racial and geographic variations. Our previous reports have indicated that a high-risk HPV 16/18 DNA was frequently detected in Chinese lung cancer patients living in ...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyl017

    authors： Fei Y,Yang J,Hsieh WC,Wu JY,Wu TC,Goan YG,Lee H,Cheng YW

    更新日期：2006-05-01 00:00:00

  • Multiple resections for hepatic and pulmonary metastases of colorectal carcinoma.

    abstract：BACKGROUND:Resections are effective for some patients with both hepatic and pulmonary metastases of colorectal cancer, but the best selection criteria for the resections and effective treatment for recurrence after the resections have not been determined. METHODS:A retrospective analysis was performed for 30 consecuti...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hym006

    authors： Takahashi S,Nagai K,Saito N,Konishi M,Nakagohri T,Gotohda N,Nishimura M,Yoshida J,Kinoshita T

    更新日期：2007-03-01 00:00:00

  • Phase II study of chemoradiotherapy for advanced squamous cell carcinoma of the thoracic esophagus: nine Japanese institutions trial.

    abstract：:A phase II study of chemoradiotherapy for advanced squamous cell carcinoma of the thoracic esophagus was carried out cooperatively by nine Japanese institutions. Forty-five patients with thoracic advanced squamous cell carcinoma, who had T4 tumor or distant lymph node metastasis (M1(LYM)), were enrolled in the study f...

    journal_title：Japanese journal of clinical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1093/oxfordjournals.jjco.a023238

    authors： Ishida K,Iizuka T,Ando N,Ide H

    更新日期：1996-10-01 00:00:00

  • Two cases of cancer-associated retinopathy combined with small-cell lung cancer.

    abstract：:Cancer-associated retinopathy is a rare paraneoplastic syndrome that is often associated with small-cell lung cancer. It is caused by an autoantibody to the 23 kDa photoreceptor protein, recoverin. A small number of reports have described effective treatment for the disease. We report two cases of cancer-associated re...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyr025

    authors： Sakamori Y,Kim YH,Okuda C,Togashi Y,Kinose D,Masago K,Mio T,Uji A,Mishima M

    更新日期：2011-05-01 00:00:00

  • Advanced esophageal cancer with esophago-bronchial fistula successfully treated by chemoradiation therapy with additional endoscopic resection: a case report.

    abstract：:Chemoradiation is potentially curative for esophageal cancer in various stages, but local failure is a major problem. The present case was a 49-year-old male diagnosed with advanced esophageal cancer with an esophago-bronchial fistula and lymph node metastasis. Histological diagnosis by biopsy was adenosquamous cell c...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyf016

    authors： Morihiro M,Boku N,Ohtsu A,Miyamoto S,Ishikura S

    更新日期：2002-02-01 00:00:00

  • Phase I trial of the MET inhibitor tepotinib in Japanese patients with solid tumors.

    abstract：OBJECTIVES:Tepotinib (MSC2156119J) is an oral, potent and highly selective small molecule mesenchymal-epithelial transition factor (MET) inhibitor for which the recommended Phase II dose of 500 mg once daily has been defined, based on the first-in-man trial conducted in the USA and Europe. We carried out a multicenter ...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1093/jjco/hyaa042

    authors： Shitara K,Yamazaki K,Tsushima T,Naito T,Matsubara N,Watanabe M,Sarholz B,Johne A,Doi T

    更新日期：2020-08-04 00:00:00

  • Nasopharyngeal carcinoma: immunohistochemical study for keratin, secretory component and leukocyte common antigen.

    abstract：:Immunohistochemical studies using antisera to keratin and secretory component (SC) and monoclonal antibody against leukocyte common antigen (LCA) were performed on 92 biopsy and autopsy specimens taken from 65 patients with nasopharyngeal carcinoma. Five biopsy specimens from malignant lymphoma of the nasopharynx and ...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：

    authors： Nomori H,Kameya T,Shimosato Y,Saito H,Ebihara S,Ono I

    更新日期：1985-03-01 00:00:00

  • A pooled analysis of primary hepatic angiosarcoma.

    abstract：BACKGROUND:Angiosarcoma is an aggressive and malignant neoplasm. Primary hepatic angiosarcoma is extremely rare and accounts for only approximately 5% of all angiosarcomas. Therefore, many doctors do not know enough about this disease; this lack of knowledge motivated us to perform this study. METHODS:We carried out a...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyaa017

    authors： Zeng D,Cheng J,Gong Z,Chen J,Long H,Zhu B

    更新日期：2020-05-05 00:00:00

  • Microsatellite instability associated with primary head and neck cancers and secondary esophageal cancers.

    abstract：BACKGROUND:It is common that patients with head and neck cancers have secondary malignant neoplasm of esophageal cancer. METHODS:To know the genetic background of the development of these secondary cancers, we performed microsatellite assay at six loci and immunohistochemical analysis on head and neck cancers of eight...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/28.12.733

    authors： Kiriu H,Yokozaki H,Yasui W,Ito K,Tahara E

    更新日期：1998-12-01 00:00:00

  • Cell cycle assessment of adoptive transferred lymphokine activated killer cells.

    abstract：:The use of lymphokine activated killer (LAK) cells for adoptive transfer therapy has been reported from number of clinical trials. To our knowledge, however, there has been no report concerning the cell cycle progression of LAK cells. Thus, for the present study we have attempted to examine the LAK cell cycle either b...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：

    authors： Watanabe R,Tanaka N,Naomoto Y,Moreira LF,Orita K

    更新日期：1994-04-01 00:00:00

  • Complementary and alternative medicine in present day oncology care: promises and pitfalls.

    abstract：:Cancer is already a well-recognized global phenomenon. The traditional approaches to cancer therapy have been surgery, radiotherapy and chemotherapy. These modalities have shown considerable promise and presently form cornerstones of management of most malignancies. However, these conventional approaches have associat...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章,评审

    doi：10.1093/jjco/hyn066

    authors： Munshi A,Ni LH,Tiwana MS

    更新日期：2008-08-01 00:00:00

  • Efficacy of reduced dose of pegfilgrastim in Japanese breast cancer patients receiving dose-dense doxorubicin and cyclophosphamide therapy.

    abstract：BACKGROUND:This retrospective study aimed to evaluate the efficacy of a 3.6-mg dose of pegfilgrastim for primary prophylaxis in Japanese breast cancer patients receiving dose-dense chemotherapy. METHODS:Patients treated with adjuvant or neoadjuvant chemotherapy for early-stage breast cancer at the Tokyo-West Tokushuka...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyw152

    authors： Mizuno Y,Fuchikami H,Takeda N,Iwai M,Sato K

    更新日期：2017-01-01 00:00:00

  • The distress and benefit to bereaved family members of participating in a post-bereavement survey.

    abstract：Background:Few studies have simultaneously collected quantitative data regarding the positive and negative effects of participating in post-bereavement surveys. Methods:We conducted a cross-sectional postal questionnaire survey in October 2013. Potential participants were caregivers for family members who had died in ...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyx177

    authors： Miyashita M,Aoyama M,Yoshida S,Yamada Y,Abe M,Yanagihara K,Shirado A,Shutoh M,Okamoto Y,Hamano J,Miyamoto A,Nakahata M

    更新日期：2018-02-01 00:00:00

  • Efficacy of CDDP and AGM-1470 chemotherapy against lung metastasis in rat osteosarcoma depends on the timing of combined administration.

    abstract：:The efficacy of combination therapy with cis-diammine-dichloroplatinum (II) (CDDP) and o-(chloroacetyl-carbamoyl) fumagillol (AGM-1470) was evaluated experimentally using a transplantable rat osteosarcoma line, previously established in our laboratory, with a high potential for metastasis. Tumor-bearing male Fischer 3...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/27.4.236

    authors： Morishita T,Mii Y,Miyauchi Y,Miura S,Honoki K,Aoki M,Kido A,Tamai S,Tsutsumi M,Konishi Y

    更新日期：1997-08-01 00:00:00

  • A phase II study of paclitaxel and nedaplatin as first-line chemotherapy in patients with advanced esophageal cancer.

    abstract：OBJECTIVE:The aim of this study was to assess the efficacy and toxicity of the combination of paclitaxel and nedaplatin as a first-line chemotherapy for patients with advanced esophageal cancer. METHODS:Patients with advanced esophageal cancer received 175 mg/m(2) of paclitaxel over a 3 h infusion, followed by nedapla...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyp058

    authors： Cao W,Xu C,Lou G,Jiang J,Zhao S,Geng M,Xi W,Li H,Jin Y

    更新日期：2009-09-01 00:00:00

  • Pseudoaneurysm of the external carotid artery branch following radiotherapy for nasopharyngeal carcinoma.

    abstract：:Rupture of irradiated arteries in patients with head and neck cancer is an uncommon complication. We present the first case of a pseudoaneurysm of the external carotid artery branch that developed after irradiation of nasopharyngeal carcinoma and was successfully treated by microcoil embolization therapy. Clinicians s...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hym019

    authors： Li SH,Hsu SW,Wang SL,Chen HC,Huang CH

    更新日期：2007-04-01 00:00:00

  • Cancer control in Australia: into the 21(st) Century.

    abstract：:Australia ranks highly internationally for cancer control, in part because cancer registries provide comprehensive national incidence and mortality and other cancer data annually. This has facilitated short- and long-term planning over the last quarter of a century. For example, male death rates from lung cancer in Au...

    journal_title：Japanese journal of clinical oncology

    pub_type： 历史文章,杂志文章

    doi：10.1093/jjco/hye121

    authors： Burton RC

    更新日期：2002-03-01 00:00:00

  • Safety, tolerability and pharmacokinetics of shorter duration of infusion of obinutuzumab in Japanese patients with B-cell non-Hodgkin lymphoma: final results of the phase II GATS study.

    abstract：Background:Shorter duration of infusion of monoclonal antibody treatments may reduce treatment burden and improve healthcare resource utilization. Methods:This phase II study recruited Japanese patients with previously untreated CD20+ B-cell non-Hodgkin lymphoma. Patients received intravenous obinutuzumab 1000 mg by r...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1093/jjco/hyy087

    authors： Ohmachi K,Ando K,Kinoshita T,Kumagai K,Hatake K,Ishikawa T,Teshima T,Kato K,Izutsu K,Ueda E,Nakai K,Kuriki H,Tobinai K

    更新日期：2018-08-01 00:00:00

  • Recent innovations in the USA National Cancer Institute-sponsored investigator initiated Phase I and II anticancer drug development.

    abstract：:Exciting recent advancements in deep-sequencing technology have enabled a rapid and cost-effective molecular characterization of patient-derived tumor samples. Incorporating these innovative diagnostic technologies into early clinical trials could significantly propel implementation of precision medicine by identifyin...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章,评审

    doi：10.1093/jjco/hyv144

    authors： Bando H,Takebe N

    更新日期：2015-11-01 00:00:00

  • Comparative study of assays for prostate-specific antigen molecular forms.

    abstract：BACKGROUND:The detection of prostate-specific antigen (PSA) molecular forms such as free PSA and PSA-ACT and the use of PSA molecular ratios, especially the percentage of free to total PSA, have been reported to improve the diagnostic accuracy of prostate cancer in the patients with slightly elevated serum PSA values. ...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/29.6.303

    authors： Kuriyama M,Uno H,Ueno K,Hamamoto Y,Vihn PQ,Ban Y

    更新日期：1999-06-01 00:00:00

  • A questionnaire survey of physicians' perspectives regarding the assessment of chemotherapy-induced peripheral neuropathy in patients with breast cancer.

    abstract：OBJECTIVE:Since there is now growing interest in the incorporation of patient-reported outcome measures in cancer clinical trials, a patient-based questionnaire, the Patient Neurotoxicity Questionnaire (PNQ) was developed to quantify the symptoms and severity of chemotherapy-induced peripheral neuropathy (CIPN). The ai...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyn100

    authors： Kuroi K,Shimozuma K,Ohashi Y,Takeuchi A,Aranishi T,Morita S,Ohsumi S,Watanabe T,Bain S,Hausheer FH

    更新日期：2008-11-01 00:00:00

  • Effectiveness of rapid titration with intravenous administration of oxycodone injection in advanced cancer patients with severe pain.

    abstract：:Some cancer patients suddenly develop severe, excruciating pain that requires rapid management using opioid medication. This study aimed to evaluate the effectiveness of rapid titration using oxycodone injection. Study subjects were advanced cancer patients who experienced severe pain (numeric rating scale ≥7) and nee...

    journal_title：Japanese journal of clinical oncology

    pub_type： 杂志文章

    doi：10.1093/jjco/hyz145

    authors： Nakajima N

    更新日期：2019-12-18 00:00:00