Microsatellite instability associated with primary head and neck cancers and secondary esophageal cancers.

abstract：:Immunohistochemical studies using antisera to keratin and secretory component (SC) and monoclonal antibody against leukocyte common antigen (LCA) were performed on 92 biopsy and autopsy specimens taken from 65 patients with nasopharyngeal carcinoma. Five biopsy specimens from malignant lymphoma of the nasopharynx and ...

journal_title：Japanese journal of clinical oncology

authors： Nomori H,Kameya T,Shimosato Y,Saito H,Ebihara S,Ono I

更新日期：1985-03-01 00:00:00

abstract：:A case of ovarian cystadenocarcinoma associated with pregnancy is reported. The semicystic left ovarian tumor was found in a 28-year-old woman, gravida 2, para 1 at 33 weeks' gestation. A primary Cesarean section, total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by chemotherapy were performed....

journal_title：Japanese journal of clinical oncology

authors： Sawada M,Yamasaki M,Urabe T,Katayama S,Yamane T

更新日期：1990-06-01 00:00:00

abstract：:Although malignant lymphoma of the breast is a rare disease, we recently experienced a high incidence of central nervous system (CNS) involvement. Thus, we retrospectively reviewed clinical records of 921 patients with breast tumors, treated from 1990 to 2002, to examine CNS involvement. Eight patients were found to h...

journal_title：Japanese journal of clinical oncology

authors： Yamazaki H,Hanada M,Kitada M,Kuyama J,Sato T,Nishikubo M,Ishida T,Inoue T,Inoue T

更新日期：2003-08-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:We retrospectively evaluated long-term oncological outcomes in patients with germ cell tumors (GCTs) primarily treated at our institution and assessed late recurrence and second primary malignancies. METHODS:This study included a total of 139 males with newly diagnosed GCTs of the testis or extragonadal orig...

journal_title：Japanese journal of clinical oncology

authors： Sato S,Tanaka T,Takahashi A,Sasai M,Kitamura H,Masumori N,Tsukamoto T

更新日期：2010-02-01 00:00:00

abstract：:We report a case of gefitinib-induced bilateral upper urinary tract bleeding in an 82-year-old woman administered the drug daily for advanced non-small cell adenocarcinoma of the lung (T4N3M0). Hematuria is an uncommon adverse effect of gefitinib, and in most cases, the bleeding site is unknown. On the 44th day of ora...

journal_title：Japanese journal of clinical oncology

authors： Mori H,Ohno Y,Ito F,Funaguchi N,Yanase K,Endo J,Nakano M,Bai La BL,Minatoguchi S

更新日期：2010-03-01 00:00:00

abstract：:The "Criteria for Evaluating the Efficacy of Chemotherapy/Radiation Therapy in the Treatment of Gastric Cancer" are now widely used in Japan. To assess the validity of the criteria, the relation between the antitumor effect evaluated by the criteria and the survival of patients with gastric cancer was analyzed. The su...

journal_title：Japanese journal of clinical oncology

authors： Kiyohashi A,Kurihara M,Yoshida S,Ohkubo T,Suga S

更新日期：1993-02-01 00:00:00

abstract：:Sixty-six patients with carcinoma of the hypopharynx or cervical esophagus received esophageal extraction and primary reconstruction. The methods of reconstruction were free forearm skin tube grafting, free jejunal transplantation and immediate pharyngo-gastrostomy after pull-through esophagectomy. Considering the pos...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Watanabe H,Iizuka T,Ebihara S,Ono I,Terui S,Harii K

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:CD10 is a cell surface metalloproteinase expressed by a variety of normal cell types, including lymphoid precursor cells, germinal center B lymphocytes and some epithelial cells. Although accumulating data indicate that CD10 expression by stromal cells is involved in colorectal carcinogenesis and it is a nov...

journal_title：Japanese journal of clinical oncology

authors： Huang WB,Zhou XJ,Chen JY,Zhang LH,Meng K,Ma HH,Lu ZF

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:Patients with T1G3 bladder cancer are at high risk of progression to muscle-invasive cancer, and early cystectomy is considered as a treatment option in this particular situation. On the other hand, understaging of T1G3 bladder cancer has been gradually proven as second or repeat transurethral resection (TUR)...

journal_title：Japanese journal of clinical oncology

authors： Shindo T,Masumori N,Fukuta F,Miyamoto S,Tsukamoto T

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:We evaluated the results of imatinib dose escalation in patients with advanced gastrointestinal stromal tumors (GISTs) after disease progression on standard-dose imatinib. METHODS:Clinical data from patients with metastatic or unresectable GISTs whose dose of imatinib was increased after disease progression ...

journal_title：Japanese journal of clinical oncology

authors： Park I,Ryu MH,Sym SJ,Lee SS,Jang G,Kim TW,Chang HM,Lee JL,Lee H,Kang YK

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:There have been no previous studies about consultation of the bereaved who have lost a loved one to cancer and ask for medical help. The aim of this study was to investigate their basic characteristics and their psychiatric disorders. METHODS:A retrospective study using clinical and background data obtained ...

journal_title：Japanese journal of clinical oncology

authors： Ishida M,Onishi H,Wada M,Tada Y,Ito H,Narabayashi M,Sasaki Y,Nomura S,Uchitomi Y

更新日期：2011-03-01 00:00:00

abstract：:We present the clinical course of a ureteroiliac arterial fistula in a patient who had been managed by ureteral stenting for 8 years for severe ureteral stricture after abdominoperineal resection with pelvic irradiation for advanced rectal cancer. A multidisciplinary team approach including provocative angiography and...

journal_title：Japanese journal of clinical oncology

authors： Yamasaki K,Omori K,Takaoka E,Sekido N,Shigai M,Mori K,Minami M,Watanabe Y,Shimazui T,Akaza H

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to specifically investigate the clinicopathological role of expression of vascular endothelial growth factor-C (VEGF-C) as well as the correlation with clinical outcomes in esophageal squamous cell carcinomas (ESCCs). METHODS:Seventy-three patients with ESCC resected in our inst...

journal_title：Japanese journal of clinical oncology

authors： Liu P,Chen W,Zhu H,Liu B,Song S,Shen W,Wang F,Tucker S,Zhong B,Wang D

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The optimal management of elderly patients with limited-disease small cell lung cancer (LD-SCLC) has not been established. METHODS:The records of elderly (>or=70 years of age) patients with LD-SCLC who had been treated with etoposide and cisplatin chemotherapy with early concurrent twice-daily thoracic radio...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takezawa K,Tachibana I,Fukuoka M,Nishimura Y,Nakagawa K

更新日期：2010-01-01 00:00:00

abstract：:The prognosis of multiple myeloma was quite poor in the last century, but it has significantly improved with the incorporation of novel agents, immunomodulatory drugs (IMiDs) and proteasome inhibitors. Thalidomide was first developed as a sedative in 1950s, but it was withdrawn from the market because of teratogenicit...

journal_title：Japanese journal of clinical oncology

authors： Abe Y,Ishida T

更新日期：2019-08-01 00:00:00

abstract：:A 72-year-old man was found to have a 12 mm solid lesion in the pancreatic tail and an 8 mm cystic lesion in the body of the pancreas by computed tomography carried out during a routine follow-up study of his adult-onset diabetes mellitus. A distal pancreatectomy was performed revealing the pancreas to have an adenoca...

journal_title：Japanese journal of clinical oncology

authors： Yoshida J,Ozaki H,Yamamoto J,Kosuge T,Takayasu K,Muramatsu Y,Mukai K

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Until 1998 in Japan, very few institutions were treating prostate cancer solely with radiotherapy (RT) >70 Gy and most were using < or =65 Gy in combination with hormone therapy. The present study reports the long-term results of RT combined with hormone therapy for localized and locally advanced prostate ca...

journal_title：Japanese journal of clinical oncology

authors： Hashine K,Numata K,Azuma K,Sumiyoshi Y,Kataoka M

更新日期：2005-11-01 00:00:00

abstract：:Hepatectomy for liver metastasis from the colo-rectum and other organs was performed in 77 cases at the National Cancer Center Hospital. The operative procedures included every variety of hepatectomy from extended resection as trisegmentectomy to small resection as partial resection. The operative mortality rate was 3...

journal_title：Japanese journal of clinical oncology

authors： Yamasaki S,Hasegawa H,Makuuchi M,Koyama Y,Hojo K,Moriya N

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:Suboptimal treatment of chemotherapy-induced nausea and vomiting and unsatisfactory response to antiemetic drugs cause impairment of cancer patient's daily functioning. This study was aimed to investigate the association of selected germline polymorphisms with ondansetron and metoclopramide response in Indone...

journal_title：Japanese journal of clinical oncology

authors： Perwitasari DA,Wessels JA,van der Straaten RJ,Baak-Pablo RF,Mustofa M,Hakimi M,Nortier JW,Gelderblom H,Guchelaar HJ

更新日期：2011-10-01 00:00:00

abstract：:Adenoid basal carcinoma of the uterine cervix is rare and its cell origin is still obscure. We report a case of adenoid basal carcinoma of the uterine cervix discovered incidentally in a 69-year-old woman who had been hysterectomized due to endometrial adenocarcinoma of the uterine corpus. Histologically, small round-...

journal_title：Japanese journal of clinical oncology

authors： Senzaki H,Osaki T,Uemura Y,Kiyozuka Y,Ogura E,Okamura A,Tsubura A

更新日期：1997-12-01 00:00:00

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：Backgrounds:With the aim to validate the applicability of the eighth T classifications of AJCC/UICC staging system for nasopharyngeal carcinoma patients. Materials and methods:We compare the seventh and eighth T classifications of the UICC/AJCC staging system in 382 newly diagnosed nasopharyngeal carcinoma patients wi...

journal_title：Japanese journal of clinical oncology

authors： Li Y,Ou X,Hu C

更新日期：2018-10-01 00:00:00

abstract：:There have been no reports describing acute exacerbations of idiopathic pulmonary fibrosis after particle radiotherapy for non-small cell lung cancer. The present study describes the case of a 76-year-old Japanese man with squamous cell carcinoma of the lung that relapsed in the left upper lobe 1 year after right uppe...

journal_title：Japanese journal of clinical oncology

authors： Nagano T,Kotani Y,Fujii O,Demizu Y,Niwa Y,Ohno Y,Nishio W,Itoh T,Murakami M,Nishimura Y

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:The correlations of serum interleukin-6 and soluble interleukin-6 receptor concentrations with clinicopathological features and survival of patients with colorectal cancer were studied. METHODS:We measured the serum levels of interleukin-6 and soluble interleukin-6 receptor in 99 colorectal cancer patients a...

journal_title：Japanese journal of clinical oncology

authors： Yeh KY,Li YY,Hsieh LL,Lu CH,Chou WC,Liaw CC,Tang RP,Liao SK

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Since there is now growing interest in the incorporation of patient-reported outcome measures in cancer clinical trials, a patient-based questionnaire, the Patient Neurotoxicity Questionnaire (PNQ) was developed to quantify the symptoms and severity of chemotherapy-induced peripheral neuropathy (CIPN). The ai...

journal_title：Japanese journal of clinical oncology

authors： Kuroi K,Shimozuma K,Ohashi Y,Takeuchi A,Aranishi T,Morita S,Ohsumi S,Watanabe T,Bain S,Hausheer FH

更新日期：2008-11-01 00:00:00

abstract：:Peripheral plasma prostaglandins (PGs) were assayed in 10 cases of gynecologic malignancies. In addition, fluctuations of PG levels during chemotherapeutically-induced gastrointestinal toxicity as well as those caused by a bolus infusion of steroid hormone were investigated. As a result, the level of PGE2 in most case...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Ohwada M,Tamada T

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:We evaluated the preoperative parameters to predict a positive surgical margin (SM) at radical prostatectomy for patients with prostate cancer. In addition, the prognostic factors for biochemical recurrence were determined in patients with positive SMs. METHODS:We retrospectively analysed 238 patients with p...

journal_title：Japanese journal of clinical oncology

authors： Hashimoto K,Masumori N,Takei F,Fukuta F,Takahashi A,Itoh N,Hasegawa T,Tsukamoto T

更新日期：2008-01-01 00:00:00

abstract：:The occurrence of multiple primary cancers in the aerodigestive tract is a well known phenomenon that has been explained by the concept of 'field carcinogenesis'. Metachronous or synchronous esophageal cancer has usually been identified in patients with head and neck cancer, gastric cancer or colon cancer. The inciden...

journal_title：Japanese journal of clinical oncology

authors： Naomoto Y,Haisa M,Yamatsuji T,Shirakawa Y,Muramatsu T,Isozaki H,Kamikawa Y,Tanaka N

更新日期：1999-07-01 00:00:00

abstract：:The techniques of aseptic procedures in the laminar airflow room (LAF) were evaluated in 110 adult patients undergoing antileukemic chemotherapy for remission induction. The patients were divided into three groups according to the regimens: Group A, consisting of 20 patients who stayed in the LAF and received the gown...

journal_title：Japanese journal of clinical oncology

authors： Takeo H,Sakurai T,Amaki I

更新日期：1983-01-01 00:00:00