Adenocarcinoma and concomitant intraductal papillary adenoma in the pancreas.

abstract：BACKGROUND:Cytokeratins (CKs) 19 and 20 have been used as targets for detecting cancer cells. We attempted to detect circulating cancer cells in patients with gastric cancer using a high-sensitivity reverse transcriptase-polymerase chain reaction (RT-PCR) assay for CK transcripts. METHODS:RT-PCR for CK 19 and CK 20 wa...

journal_title：Japanese journal of clinical oncology

authors： Majima T,Ichikura T,Takayama E,Chochi K,Mochizuki H

更新日期：2000-11-01 00:00:00

abstract：:Cytotoxic effects of mannosamine and free fatty acids on human malignant T-lymphoid cell lines derived from patients with T-cell leukemia were investigated. The combination of mannosamine and an unsaturated fatty acid (oleate or linoleate) produced more striking cytotoxic effects on malignant lymphoid cells than on no...

journal_title：Japanese journal of clinical oncology

authors： Onoda T,Morikawa S,Harada T,Morikawa K

更新日期：1985-09-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To confirm the safety and efficacy of everolimus in patients with unresectable or metastatic RCC. METHODS:Patients with unresectable or metastatic RCC were included and were followed for up to 1 year from the start of everolimus. The study was conducted at 618 investigational sites in Japan from March 2010 t...

journal_title：Japanese journal of clinical oncology

authors： Akaza H,Kurihara R,Katsura A,Harumiya M,Ushida N

更新日期：2019-10-01 00:00:00

abstract：:Brachytherapy is an invasive therapy with placement of radiation source into or near the tumor. The difference between planning target volume and clinical target volume is minimal, and the dose out of the tumor reduces rapidly due to the inverse-square law. High-dose-rate brachytherapy enables three-dimensional image ...

journal_title：Japanese journal of clinical oncology

authors： Itami J

更新日期：2020-05-05 00:00:00

abstract：:A 50-year-old man underwent a left nephrectomy for renal cell carcinoma of the clear cell type in February, 1978. He was examined using computed tomography in September, 1993, and was found to have a small coin lesion in his right lung. A fine needle aspiration biopsy failed to disclose any tumor cells. He underwent a...

journal_title：Japanese journal of clinical oncology

authors： Yoshida J,Nagai K,Hasebe T,Takahashi K,Nishimura M,Otsuka S,Nishiwaki Y,Kodama T

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:We conducted a questionnaire survey of oncology specialists to investigate the frequency of administration of different drugs for the management of chemotherapy-induced peripheral neuropathy in Japan in 2015. Our group published Clinical Guidelines for the Management of Chemotherapy-Induced Peripheral Neuropa...

journal_title：Japanese journal of clinical oncology

authors： Hirayama Y,Yoshida Y,Mori M,Tamura K

更新日期：2020-08-04 00:00:00

abstract：Background:Many patients with colorectal cancer are elderly with competing comorbidities. When constructing nomogram for assessing survival, we should consider the influence of competing risk. A competing-risks nomogram was developed to estimate the probability of death due to colorectal cancer for patients after curat...

journal_title：Japanese journal of clinical oncology

authors： Li J,Li X,Gu J,Ma X,Xue F

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to clarify the efficacy and toxicity of hyperfractionated radiation therapy (RT) for patients with nasopharyngeal cancer (NPC). METHODS:Twenty-two patients with NPC treated at our hospital between April 1994 and December 2002 were the subjects of this study. They received hyperfr...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Uno T,Kawakami H,Ueno N,Aruga T,Yasuda S,Hanazawa T,Okamoto Y,Ito H,Shigematsu N

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the prognostic importance of the sequencing of radiation therapy and chemotherapy after mastectomy in high-risk premenopausal women with breast cancer in addition to other known prognostic factors in the literature. METHODS:In this retrospective study, 176 premenopau...

journal_title：Japanese journal of clinical oncology

authors： Cakir S,Gursel B,Meydan D,Yildiz L

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Fibulin-1 is a member of the fibulin gene family, characterized by tandem arrays of epidermal growth factor-like domains and a C-terminal fibulin-type module. Fibulin-1 plays important roles in a range of cellular functions including morphology, growth, adhesion and mobility. It acts as a tumor suppressor gen...

journal_title：Japanese journal of clinical oncology

authors： Cui Y,Liu J,Yin HB,Liu YF,Liu JH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:There have been few reports of sarcoid reaction in the regional lymph nodes associated with lung cancer. The purpose of this study was to analyze the surgical results of lung cancer with sarcoid reaction. METHODS:Of 1733 lung cancer patients undergoing surgical treatment in our institute from 1990 to 2004, ...

journal_title：Japanese journal of clinical oncology

authors： Tomimaru Y,Higashiyama M,Okami J,Oda K,Takami K,Kodama K,Tsukamoto Y

更新日期：2007-02-01 00:00:00

abstract：:A rare case of adult T-cell leukemia/lymphoma with a giant exophytic gastric tumor invading the anterior abdominal wall is presented. The patient was a 52-year-old woman, who had a history of strongyloidiasis. Although the patient was serologically positive for HTLV-I antibody, there were no lymphoma cells in the peri...

journal_title：Japanese journal of clinical oncology

authors： Hiroyasu S,Shiraishi M,Shimabukuro M,Kusano T,Muto Y

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Overweight and obesity, indicated as increased body mass index, are associated with the risk of some cancers. We carried out a meta-analysis on published cohort and case-control studies to assess the strength of association between body mass index and gastric cancer. METHODS:Relevant studies were identified ...

journal_title：Japanese journal of clinical oncology

authors： Lin XJ,Wang CP,Liu XD,Yan KK,Li S,Bao HH,Zhao LY,Liu X

更新日期：2014-09-01 00:00:00

abstract：:The present report describes two cases of renal cell carcinoma extending into the vena cava and the right atrium. The treatment was total nephrectomy and tumor thrombectomy, utilizing extracorporeal circulation. The aggressive surgical management of this progressive malignant disease is discussed. ...

journal_title：Japanese journal of clinical oncology

authors： Cho M,Ozono S,Takashima K,Moriya A,Hirao Y,Okajima E,Taniguchi S,Niwaya K,Kawachi K,Kitamura S

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to identify clinicopathological variables associated with the clinical outcomes of patients with lymph node metastasis-positive urothelial bladder carcinoma after radical cystectomy. METHODS:Forty-six patients who underwent radical cystectomy without preoperative chemotherapy and ha...

journal_title：Japanese journal of clinical oncology

authors： Nakagawa T,Kanai Y,Nakanishi H,Komiyama M,Fujimoto H

更新日期：2012-11-01 00:00:00

abstract：:Head and neck cancer is a major cause of morbidity and mortality in Hong Kong. HNC is well-known for its heterogeneity in epidemiology, clinical behavior, clinic-pathological features and patient characteristics. Treatment strategies for this heterogeneous disease vary greatly in different parts of the world, dependin...

journal_title：Japanese journal of clinical oncology

authors： Ng WT,Wong ECY,Lee VHF,Chan JYW,Lee AWM

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Patients with end-stage renal disease are suggestive to have a higher risk for the development of some kinds of cancer. The aim of this study is to evaluate the possible association between malignancy and end-stage renal disease in Taiwan. METHODS:We used the data of the National Health Insurance system of T...

journal_title：Japanese journal of clinical oncology

authors： Liang JA,Sun LM,Yeh JJ,Sung FC,Chang SN,Kao CH

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Although a series of histopathological criteria have been suggested, the prediction of the malignant potential of gastrointestinal stromal tumors (GIST) is still difficult. The older literature called all gastrointestinal stromal tumors smooth muscle tumors or mixed GIST with true smooth muscle tumors. Repor...

journal_title：Japanese journal of clinical oncology

authors： Wang X,Mori I,Tang W,Utsunomiya H,Nakamura M,Nakamura Y,Zhou G,Kennichi K

更新日期：2002-09-01 00:00:00

abstract：Purpose:To investigate the usefulness of screening for patient symptoms as the fifth vital sign using an electronic medical recording system. Patients and methods:In the electronic medical recording system, all admitted patients received routine nurse-based assessment of discomfort (defined as any physical symptom) at...

journal_title：Japanese journal of clinical oncology

authors： Naito AS,Sakuma Y,Kinoshita H,Ito T,Mimatsu S,Tarumi A,Kiyohara E,Morita T

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical applications of stereotactic body radiation therapy (SBRT) using the CyberKnife system for pelvic recurrence from rectal cancer with a focus on survival and toxicity. METHODS:Between 2002 and 2006, 23 patients with recurrent rectal cancer were treated with SBRT at our institution....

journal_title：Japanese journal of clinical oncology

authors： Kim MS,Choi C,Yoo S,Cho C,Seo Y,Ji Y,Lee D,Hwang D,Moon S,Kim MS,Kang H

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as advanced and inoperable due to the lack of effective biomarkers and poor sensitivity of clinical diagnosis. Here, we aimed to identify the genomic profile of CCA and provided molecular evidence for further biomarker development. ME...

journal_title：Japanese journal of clinical oncology

authors： Jiang G,Zhang W,Wang T,Ding S,Shi X,Zhang S,Shi W,Liu A,Zheng S

更新日期：2020-09-28 00:00:00

abstract：:A randomized Phase III trial commenced in Japan in September 2014. Endoscopic local steroid injection has been commonly used and considered acceptable as the current standard treatment for the prevention of esophageal stricture after endoscopic submucosal dissection for superficial esophageal cancer. The purpose of th...

journal_title：Japanese journal of clinical oncology

authors： Mizutani T,Tanaka M,Eba J,Mizusawa J,Fukuda H,Hanaoka N,Takeuchi M,Aoyama I,Kojima T,Takizawa K,Ono H,Muto M,Gastrointestinal Endoscopy Study Group of the Japan Clinical Oncology Group (JCOG).

更新日期：2015-11-01 00:00:00

abstract：:New drug delivery systems for cis-diamminedichloroplatinum (CDDP) incorporated into vehicles, such as polymethylmethacrylate (PMMA), fibrin glue (F.G.), alpha-tricalciumphosphate (TCP) and ethylenevinyleacetate copolymer (Polymer) were examined using a rat osteosarcoma model. The materials containing CDDP were directl...

journal_title：Japanese journal of clinical oncology

authors： Miura S,Mii Y,Miyauchi Y,Ohgushi H,Morishita T,Hohnoki K,Aoki M,Tamai S,Konishi Y

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Abiraterone acetate has been approved in >70 countries for chemotherapy-naïve metastatic castration-resistant prostate cancer patients. Efficacy and safety of abiraterone acetate (1000 mg/once daily) with prednisolone (5 mg/twice daily) in chemotherapy-naïve Japanese patients with metastatic castration-resist...

journal_title：Japanese journal of clinical oncology

authors： Matsubara N,Uemura H,Satoh T,Suzuki H,Nishiyama T,Uemura H,Hashine K,Imanaka K,Ozono S,Akaza H

更新日期：2014-12-01 00:00:00

abstract：:Sixty-six patients with carcinoma of the hypopharynx or cervical esophagus received esophageal extraction and primary reconstruction. The methods of reconstruction were free forearm skin tube grafting, free jejunal transplantation and immediate pharyngo-gastrostomy after pull-through esophagectomy. Considering the pos...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Watanabe H,Iizuka T,Ebihara S,Ono I,Terui S,Harii K

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the efficacy and toxicity of the combination of paclitaxel and nedaplatin as a first-line chemotherapy for patients with advanced esophageal cancer. METHODS:Patients with advanced esophageal cancer received 175 mg/m(2) of paclitaxel over a 3 h infusion, followed by nedapla...

journal_title：Japanese journal of clinical oncology

authors： Cao W,Xu C,Lou G,Jiang J,Zhao S,Geng M,Xi W,Li H,Jin Y

更新日期：2009-09-01 00:00:00

abstract：:Malignant neoplasm has become the leading cause of death in Taiwan since 1982. There has been a decreasing trend for cancers of the stomach and cervix uteri, while an increasing trend has been observed for cancers of the lung, liver, oral cavity, colon and rectum, breast and prostate. International comparison and migr...

journal_title：Japanese journal of clinical oncology

authors： Chen CJ,You SL,Lin LH,Hsu WL,Yang YW

更新日期：2002-03-01 00:00:00