Head and neck cancer in Hong Kong.

abstract：:Cases of hyperfractionated radiotherapy and adjuvant chemotherapy for nasopharyngeal cancer are reported. Seven patients received hyperfractionated radiotherapy (76.8-81.6 Gy/64-68 fractions to primary tumor) and two cycles of cisplatin (80 mg/m2 i.v. on day 1) plus 5-FU (800 mg/m2 continuous infusion on days 2-6). Mu...

journal_title：Japanese journal of clinical oncology

authors： Toita T,Ogawa K,Kamata M,Kojya S,Itokazu T,Kakinohana Y,Iraha S,Yoshinaga M,Zukeran Y,Sawada S

更新日期：1999-03-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the relationship of HIF-1alpha expression and tumor angiogenesis, recurrence/distant metastasis, and its value in the prediction of aggressive behavior of gastrointestinal stromal tumor (GIST). METHODS:Paraffin-embedded specimens from 62 patients with GIST were di...

journal_title：Japanese journal of clinical oncology

authors： Chen WT,Huang CJ,Wu MT,Yang SF,Su YC,Chai CY

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Multi-combination chemotherapy consisting of anthracyclines has been effective but has not invariably prolonged the survival period in advanced/recurrent breast cancer. The possibility has been discussed that chemoendocrine therapy combined with endocrine agents is more effective. METHODS:In order to evalua...

journal_title：Japanese journal of clinical oncology

authors： Tominaga T,Nomura Y,Uchino J,Hirata K,Kimura M,Yoshida M,Aoyama H,Kinoshita H,Koyama H,Monden Y,Takashima S,Ogawa M

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation is the treatment of choice in young patients with severe aplastic anemia. The main causes of failure after this procedure are graft versus host disease, infections and graft failure, often exacerbated by large numbers of transfusions and prolonged disease du...

journal_title：Japanese journal of clinical oncology

authors： Rzepecki P,Sarosiek T,Szczylik C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Benefits of chemotherapy have generally been modest in gastric cancer, although those regimens developed more recently have produced higher response rates. Paclitaxel plus cisplatin is one such regimen and divided administration of paclitaxel has been suggested to be associated with lower neurological and he...

journal_title：Japanese journal of clinical oncology

authors： Kim YH,Yamaguchi K,Bang YJ,Takiuchi H,Kang WK,Sato A,Kang YK,Sakamoto J,Abe C,Sakata Y

更新日期：2007-07-01 00:00:00

abstract：:The concepts of lifetime and age-conditional probabilities of developing and dying of cancer are introduced as indexes to understand the risk of cancer. In this paper, we estimated the lifetime and age-conditional probabilities of developing and dying of cancer in 2001 and 2005, respectively, in Japan. It is estimated...

journal_title：Japanese journal of clinical oncology

authors： Kamo K,Katanoda K,Matsuda T,Marugame T,Ajiki W,Sobue T

更新日期：2008-08-01 00:00:00

abstract：:Primary cardiac angiosarcoma is a rare, diagnostically elusive disease with a poor prognosis. In this report, we describe the case of a 56-year-old woman with a right atrial angiosarcoma. The patient presented with impending cardiac tamponade caused by right atrial perforation, but was misdiagnosed as a ruptured aneur...

journal_title：Japanese journal of clinical oncology

authors： Yoshitake I,Hata M,Sezai A,Niino T,Unosawa S,Shimura K,Kasamaki Y,Minami K

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:We conducted a dose-finding and feasibility study in which we administered a fixed dose 3-h infusion of paclitaxel and an escalating dose of cisplatin in Japanese patients with advanced non-small cell lung cancer. METHODS:Chemotherapy consisted of fixed dose (210 mg/m(2)) paclitaxel given over 3 h on day 1 ...

journal_title：Japanese journal of clinical oncology

authors： Watanabe H,Yamamoto N,Tamura T,Shimoyama T,Hotta K,Inoue A,Sawada M,Akiyama Y,Kusaba H,Nokihara H,Sekine I,Kunitoh H,Ohe Y,Kodama T,Saijo N

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:A Patterns of Care Study (PCS) has been conducted to evaluate the standards of practice for prostate cancer patients treated with radiotherapy in Japan. This study examines the influence of institutional stratification on the process of care for patients receiving radical external beam radiotherapy for prost...

journal_title：Japanese journal of clinical oncology

authors： Ogawa K,Nakamura K,Sasaki T,Yamamoto T,Koizumi M,Teshima T,Inoue T,Japanese Patterns of Care Study Working Subgroup on Prostate Cancer.

更新日期：2004-01-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The correlations of serum interleukin-6 and soluble interleukin-6 receptor concentrations with clinicopathological features and survival of patients with colorectal cancer were studied. METHODS:We measured the serum levels of interleukin-6 and soluble interleukin-6 receptor in 99 colorectal cancer patients a...

journal_title：Japanese journal of clinical oncology

authors： Yeh KY,Li YY,Hsieh LL,Lu CH,Chou WC,Liaw CC,Tang RP,Liao SK

更新日期：2010-06-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：:Uterine inversion caused by uterine sarcoma is a rare condition with 12 reported cases to date according to a MEDLINE search. We report two cases of this rare condition. A 71- and a 72-year-old woman presented with uterine sarcomas rapidly extruded into the vagina. In both cases, magnetic resonance imaging (MRI) scans...

journal_title：Japanese journal of clinical oncology

authors： Takano K,Ichikawa Y,Tsunoda H,Nishida M

更新日期：2001-01-01 00:00:00

abstract：:The joint international symposium of the 22nd Hiroshima Cancer Seminar and the 4th Japanese Association for RNA Interference focused on a pivotal role of microRNAs in carcinogenesis, progression and therapy of human cancer. Mammalian immune regulator MCPIP1 (Zc3h12a) RNase acts as a novel suppressor of microRNA activi...

journal_title：Japanese journal of clinical oncology

authors： Tahara H,Kay MA,Yasui W,Tahara E

更新日期：2013-05-01 00:00:00

abstract：:This report describes a 78-year-old woman with insulinoma, treated with a combination of diphenylhydantoin and a calcium antagonist. The effectiveness of 200 mg of diphenylhydantoin and 180 mg of diltiazem was evaluated by measuring the levels of plasma glucose, immunoreactive insulin and immunoreactive insulin/plasma...

journal_title：Japanese journal of clinical oncology

authors： Imanaka S,Matsuda S,Ito K,Matsuoka T,Okada Y

更新日期：1986-03-01 00:00:00

abstract：Objective:The prognostic value of metabolic parameters using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has not been established for early non-small cell lung cancer (NSCLC). Accordingly, the authors investigated the prognostic value of metabolic parameters in terms of failure ...

journal_title：Japanese journal of clinical oncology

authors： Lee J,Lee M,Koom WS,Kim HJ,Kim WC

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Uracil-tegafur (UFT) has been reported to have broad antitumor activity in a variety of malignancies. However, its activity in biliary tract carcinoma has not been fully evaluated. The aim of this study was to evaluate the antitumor activity and toxicity of UFT in chemotherapy-naive patients with advanced bi...

journal_title：Japanese journal of clinical oncology

authors： Ikeda M,Okusaka T,Ueno H,Morizane C,Furuse J,Ishii H

更新日期：2005-08-01 00:00:00

abstract：:Comprehensive genomic profiling using next-generation sequencing technologies provides insights into understanding the genomic architecture of human cancer. This new understanding of the cancer genome allows us to identify many more genomic alterations occurring within tumors than before, some of which could be potent...

journal_title：Japanese journal of clinical oncology

authors： Kou T,Kanai M,Matsumoto S,Okuno Y,Muto M

更新日期：2016-05-01 00:00:00

abstract：:We report a case of gefitinib-induced bilateral upper urinary tract bleeding in an 82-year-old woman administered the drug daily for advanced non-small cell adenocarcinoma of the lung (T4N3M0). Hematuria is an uncommon adverse effect of gefitinib, and in most cases, the bleeding site is unknown. On the 44th day of ora...

journal_title：Japanese journal of clinical oncology

authors： Mori H,Ohno Y,Ito F,Funaguchi N,Yanase K,Endo J,Nakano M,Bai La BL,Minatoguchi S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Patients with end-stage renal disease are suggestive to have a higher risk for the development of some kinds of cancer. The aim of this study is to evaluate the possible association between malignancy and end-stage renal disease in Taiwan. METHODS:We used the data of the National Health Insurance system of T...

journal_title：Japanese journal of clinical oncology

authors： Liang JA,Sun LM,Yeh JJ,Sung FC,Chang SN,Kao CH

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Perinephric fat invasion (PFI) of renal cell carcinoma (RCC) is known to be associated with adverse pathological features and poor prognosis. We analyzed these associations using a sub-group of the RCC registry of The Cancer Registration Committee of the Japanese Urological Association. METHODS:The study co...

journal_title：Japanese journal of clinical oncology

authors： Kume H,Homma Y,Shinohara N,Obara W,Kondo T,Kimura G,Fujimoto H,Nonomura N,Hongo F,Sugiyama T,Takahashi M,Kanayama HO,Fukumori T,Eto M

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:One of the most studied pro-angiogenic factors involved in the development of colorectal cancer is the vascular endothelial growth factor (VEGF). The small molecule tyrosine kinase inhibitor semaxanib (SU5416) is one of the several agents targeting the VEGF signaling pathway, and its development centered mos...

journal_title：Japanese journal of clinical oncology

authors： Hoff PM,Wolff RA,Bogaard K,Waldrum S,Abbruzzese JL

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:This phase I/II study determined the recommended dose of FOLFIRI (irinotecan, infusional 5-fluorouracil and leucovorin) for Japanese patients with advanced colorectal cancer, and evaluated safety at the recommended dose in patients without the UDP-glucuronosyltransferase 1A1*28 allele which caused reduced enz...

journal_title：Japanese journal of clinical oncology

authors： Yamashita K,Nagashima F,Fujita K,Yamamoto W,Endo H,Miya T,Narabayashi M,Kawara K,Akiyama Y,Ando Y,Ando M,Sasaki Y

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To determine the antitumor activity and toxicity of weekly hepatic arterial infusion (HAI) of 5-fluorouracil (5-FU) for liver metastases from colorectal cancer. In addition, the present study also evaluated the efficacy of second-line chemotherapy after termination of HAI. METHODS:A retrospective study was d...

journal_title：Japanese journal of clinical oncology

authors： Hosokawa A,Yamada Y,Shimada Y,Muro K,Matsumura Y,Fujita S,Akasu T,Moriya Y,Shirao K

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:We aimed to assess the potency and efficacy of tropisetron, a 5-HT3 receptor antagonist, in the prevention of nausea and emesis observed in the pediatric patient population taking various chemotherapy protocols. METHODS:Tropisetron (Navoban) was given to 100 children (62 boys and 38 girls aged 6 months to 1...

journal_title：Japanese journal of clinical oncology

authors： Ozkan A,Yildiz I,Yüksel L,Apak H,Celkan T

更新日期：1999-02-01 00:00:00

abstract：:The use of lymphokine activated killer (LAK) cells for adoptive transfer therapy has been reported from number of clinical trials. To our knowledge, however, there has been no report concerning the cell cycle progression of LAK cells. Thus, for the present study we have attempted to examine the LAK cell cycle either b...

journal_title：Japanese journal of clinical oncology

authors： Watanabe R,Tanaka N,Naomoto Y,Moreira LF,Orita K

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the risk factors for sentinel lymph node metastasis and validate the value of the Memorial Sloan-Kettering Cancer Center nomogram for the prediction of sentinel lymph node metastasis in breast cancer patients. METHODS:A sentinel lymph node biopsy database containing 1227 consecutive breast cancer...

journal_title：Japanese journal of clinical oncology

authors： Qiu PF,Liu JJ,Wang YS,Yang GR,Liu YB,Sun X,Wang CJ,Zhang ZP

更新日期：2012-11-01 00:00:00

abstract：:An immunohistochemical study of a rare initial manifestation of non-Hodgkin's lymphoma (NHL) in the ovaries is presented. There have been very few reports to date on immunohistochemical studies of lymphoma involving the ovaries. A 53-year-old woman suffering from lower abdominal pain and abnormal genital bleeding was ...

journal_title：Japanese journal of clinical oncology

authors： Yamane T,Kirimoto K,Fujita M,Naka T,Tsubakio T,Ishikawa K,Nobunaga T,Tanaka F,Yamasaki M

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:We evaluated whether color Doppler ultrasound (US) had diagnostic accuracy equal to dynamic computed tomography (CT) and whether performing dynamic CT and Doppler US together would be more informative in preoperative diagnosis of renal solid tumors. METHODS:A total of 110 renal solid tumors smaller than 7 c...

journal_title：Japanese journal of clinical oncology

authors： Kitamura H,Fujimoto H,Tobisu K,Mizuguchi Y,Maeda T,Matsuoka N,Komiyama M,Nakagawa T,Kakizoe T

更新日期：2004-02-01 00:00:00