A phase II study of paclitaxel and nedaplatin as first-line chemotherapy in patients with advanced esophageal cancer.

abstract：BACKGROUND:As clinical trials for limited-disease small-cell lung cancer often exclude elderly patients due to comorbidities and a decline in organ function, the most suitable treatment for limited-disease small-cell lung cancer patients aged 75 years or older still remains unclear. METHODS:From July 2002 to June 2011...

journal_title：Japanese journal of clinical oncology

authors： Shukuya T,Takahashi T,Harada H,Ono A,Akamatsu H,Taira T,Kenmotsu H,Naito T,Murakami H,Endo M,Takahashi K,Yamamoto N

更新日期：2013-02-01 00:00:00

abstract：:Previous studies have demonstrated the monoclonal antibody, TFS-4, to recognize a cell surface antigen, 124,000 Daltons, of molecular weight expressed selectively on small cell lung cancer but not on non-small cell lung cancer, and to cross-react with the human brain, cardiac muscle and some smooth muscle cells. The c...

journal_title：Japanese journal of clinical oncology

authors： Umezawa Y,Kuge S,Kikyo N,Shirai T,Watanabe J,Fugisawa M,Okabe T

更新日期：1991-08-01 00:00:00

abstract：Backgrounds:Stereotactic ablative radiotherapy (SABR) is one of the newly developed innovative radiotherapy and of which optimal dose prescription needs to be standardized. We aimed to investigate the dose-response relationship for patients with SABR. Methods:Fifty-three patients with Stage I non-small cell lung cance...

journal_title：Japanese journal of clinical oncology

authors： Jeon W,Ahn SJ,Kim YC,Oh IJ,Park CK,Jeong JU,Yoon MS,Song JY,Nam TK,Chung WK

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Combination of bleomycin, etoposide and cisplatin (BEP) remains the standard chemotherapy for testicular cancer. Since the development of BEP in the 1980s, there has been a considerable advance in supportive therapies, such as granulocyte colony-stimulating-factor and 5-HT3 antagonists. Therefore, we re-eval...

journal_title：Japanese journal of clinical oncology

authors： Kawai K,Ando S,Hinotsu S,Oikawa T,Sekido N,Miyanaga N,Shimazui T,Akaza H

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:It has been reported that prognosis is less favorable in poorly (G3) differentiated endometrioid adenocarcinoma than in well (G1) or moderately (G2) differentiated endometrioid adenocarcinoma. The goal of this study is therefore to analyze the prognosis of G3 endometrioid adenocarcinoma and various factors t...

journal_title：Japanese journal of clinical oncology

authors： Kuwabara Y,Susumu N,Banno K,Hirao T,Kawaguchi M,Yamagami W,Suzuki N,Aoki D,Nozawa S

更新日期：2005-01-01 00:00:00

abstract：:We report a case of amelanotic malignant melanoma of the female urethra. The clinical course was unusually long and complicated by asynchronous resectable metastases to the lung and the brain. The patient died of generalized metastasis in spite of successful resection of the metastatic lesions and post-operative chemo...

journal_title：Japanese journal of clinical oncology

authors： Sugaya K,Yazaki T,Ishikawa S,Kanoh S

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to re-evaluate post-remission therapy outcomes after first remission according to years of patient enrollment in patients with core binding factor acute myeloid leukaemia. METHODS:We conducted a retrospective study on 138 patients aged less than 60 years diagnosed with core bind...

journal_title：Japanese journal of clinical oncology

authors： Shin HJ,Kim HJ,Sohn SK,Min YH,Won JH,Kim I,Yoon HJ,Lee JH,Jo DY,Joo YD,Jung CW,Lee KH,Korean Society of Hematology, AML\/MDS Working Party.,Chung JS,Ahn JS,Kim SJ,Lee JH,Choi SJ,Lee JH,Bae SH,Hong DS,Zang DY,K

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical applications of stereotactic body radiation therapy (SBRT) using the CyberKnife system for pelvic recurrence from rectal cancer with a focus on survival and toxicity. METHODS:Between 2002 and 2006, 23 patients with recurrent rectal cancer were treated with SBRT at our institution....

journal_title：Japanese journal of clinical oncology

authors： Kim MS,Choi C,Yoo S,Cho C,Seo Y,Ji Y,Lee D,Hwang D,Moon S,Kim MS,Kang H

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Trop-1/Ep-CAM modulates growth and survival of transformed cells, and it is highly expressed in most carcinomas including breast cancer. Only membranous staining is typically considered in evaluating Trop-1/epithelial cell adhesion molecule (Ep-CAM) expression in tumor cells. However, there is evidence of ret...

journal_title：Japanese journal of clinical oncology

authors： Alberti S,Ambrogi F,Boracchi P,Fornili M,Querzoli P,Pedriali M,La Sorda R,Lattanzio R,Tripaldi R,Piantelli M,Biganzoli E,Coradini D

更新日期：2012-12-01 00:00:00

abstract：:Myxoid liposarcoma can frequently metastasize to extrapulmonary sites. We present two cases of myxoid liposarcoma metastatic to the epidural space. Both patients complained of back pain, but plain radiography revealed no abnormality. MR imaging clearly demonstrated metastatic tumors in the epidural space, but no invol...

journal_title：Japanese journal of clinical oncology

authors： Ogose A,Hotta T,Inoue Y,Sakata S,Takano R,Yamamura S

更新日期：2001-09-01 00:00:00

abstract：:The Japan Public Health Center-based prospective Study conducted a baseline survey for 140 000 registered residents aged 40-69 years within 11 public health center areas nationwide in 1990-94. Five- and 10-year follow-up surveys were conducted to update information on lifestyle habits and health conditions. In total, ...

journal_title：Japanese journal of clinical oncology

authors： Tsugane S,Sawada N

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:One of the most studied pro-angiogenic factors involved in the development of colorectal cancer is the vascular endothelial growth factor (VEGF). The small molecule tyrosine kinase inhibitor semaxanib (SU5416) is one of the several agents targeting the VEGF signaling pathway, and its development centered mos...

journal_title：Japanese journal of clinical oncology

authors： Hoff PM,Wolff RA,Bogaard K,Waldrum S,Abbruzzese JL

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Fibulin-1 is a member of the fibulin gene family, characterized by tandem arrays of epidermal growth factor-like domains and a C-terminal fibulin-type module. Fibulin-1 plays important roles in a range of cellular functions including morphology, growth, adhesion and mobility. It acts as a tumor suppressor gen...

journal_title：Japanese journal of clinical oncology

authors： Cui Y,Liu J,Yin HB,Liu YF,Liu JH

更新日期：2015-09-01 00:00:00

abstract：:Endometrial stromal sarcoma is known to be a hormone-dependent tumor. Efficacy of hormonal therapy including high-dose progestins, aromatase inhibitors or gonadotropin-releasing hormone analogs has been reported. We report a case of recurrent endometrial stromal sarcoma, the tumor cells of which were strongly positive...

journal_title：Japanese journal of clinical oncology

authors： Akashi D,Todo Y,Shimada C,Okamoto K,Minobe S,Kato H

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Overweight and obesity, indicated as increased body mass index, are associated with the risk of some cancers. We carried out a meta-analysis on published cohort and case-control studies to assess the strength of association between body mass index and gastric cancer. METHODS:Relevant studies were identified ...

journal_title：Japanese journal of clinical oncology

authors： Lin XJ,Wang CP,Liu XD,Yan KK,Li S,Bao HH,Zhao LY,Liu X

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The natural history and posttherapeutic outcome of adenomatous hyperplasia and early hepatocellular carcinoma have rarely been analyzed. METHODS:Fifty-three hepatic tumors diagnosed as adenomatous hyperplasia or early hepatocellular carcinoma and followed up for more than 6 months and 141 patients with sing...

journal_title：Japanese journal of clinical oncology

authors： Sakamoto M,Hirohashi S

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Multi-combination chemotherapy consisting of anthracyclines has been effective but has not invariably prolonged the survival period in advanced/recurrent breast cancer. The possibility has been discussed that chemoendocrine therapy combined with endocrine agents is more effective. METHODS:In order to evalua...

journal_title：Japanese journal of clinical oncology

authors： Tominaga T,Nomura Y,Uchino J,Hirata K,Kimura M,Yoshida M,Aoyama H,Kinoshita H,Koyama H,Monden Y,Takashima S,Ogawa M

更新日期：1998-04-01 00:00:00

abstract：:In order to study the characteristics of lung cancer in smokers and nonsmokers, clinico-epidemiological features of 943 lung cancer patients treated in the Aichi Cancer Center Hospital from 1964-77 were analyzed according to their smoking histories. About 70% of both male and female patients who smoked fell in Group I...

journal_title：Japanese journal of clinical oncology

authors： Shimizu H,Tominaga S,Nishimura M,Urata A

更新日期：1984-12-01 00:00:00

abstract：:We encountered a patient with hepatocellular carcinoma (HCC) with peritoneal dissemination and needle tract implantation, both of which were strongly suspected to have been caused by percutaneous needle biopsy. The patient was a 65-year-old man. Partial hepatectomy of subsegment VI had been performed following the dia...

journal_title：Japanese journal of clinical oncology

authors： Takahashi H,Konishi M,Nakagohri T,Inoue K,Takahashi S,Tanizawa Y,Monden M,Kinoshita T

更新日期：2004-09-01 00:00:00

abstract：:The "Criteria for Evaluating the Efficacy of Chemotherapy/Radiation Therapy in the Treatment of Gastric Cancer" are now widely used in Japan. To assess the validity of the criteria, the relation between the antitumor effect evaluated by the criteria and the survival of patients with gastric cancer was analyzed. The su...

journal_title：Japanese journal of clinical oncology

authors： Kiyohashi A,Kurihara M,Yoshida S,Ohkubo T,Suga S

更新日期：1993-02-01 00:00:00

abstract：:A case of multiple thymoma is reported. The patient was a 28-year-old woman who came to us with myasthenia gravis. There were two separate thymoma in the anterior mediastinum: one measured 70 x 30 x 30 mm, while the other was 1.5 mm in diameter and situated in the surrounding thymic tissue. A histological study reveal...

journal_title：Japanese journal of clinical oncology

authors： Nomori H,Kobayashi K,Ishihara T,Suito T,Torikata C

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVE:Breast cancer is a heterogeneous disease. The aim of this prospective study, in which fluorescence in situ hybridization was used to determine human epidermal growth factor receptor 2 status in primary breast cancers and in the lymph node metastases, was to verify the stability of human epidermal growth facto...

journal_title：Japanese journal of clinical oncology

authors： Aoyama K,Kamio T,Nishikawa T,Kameoka S

更新日期：2010-07-01 00:00:00

abstract：:The main purpose of the study was to evaluate quality of life (QOL) among cancer patients using the WHOQOL-100 instrument and to see if any significant differences were seen in cancer stages, treatment status and prognosis. This study consisted of two parts; qualitative and quantitative. For the qualitative study, two...

journal_title：Japanese journal of clinical oncology

authors： Tazaki M,Nakane Y,Endo T,Kakikawa F,Kano K,Kawano H,Kuriyama K,Kuroko K,Miyaoka E,Ohta H,Okamoto N,Shiratori S,Takamiya S,Tanemura K,Tsuchiya R

更新日期：1998-02-01 00:00:00

abstract：:Bortezomib is a proteasome inhibitor and is active against multiple myeloma. Most toxicities associated with bortezomib are mild to moderate and manageable; however, bortezomib-induced pneumonitis has been reported in some multiple myeloma cases. Bortezomib-induced pneumonitis was reported to occur relatively soon aft...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi T,Sasaki M,Itoh K

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:The treatment modality for desmoid-type fibromatosis has shifted from surgery to conservative treatment. This systematic review aims to evaluate the efficacy of low-dose chemotherapy with methotrexate and vinblastine for patients with extra-abdominal desmoid-type fibromatosis. METHODS:We searched the pertine...

journal_title：Japanese journal of clinical oncology

authors： Shimizu K,Hamada S,Sakai T,Koike H,Yoshida M,Nishida Y

更新日期：2020-04-07 00:00:00

abstract：:Cancer originating in the biliary tract can be classified as bile duct cancer (cholangiocarcinoma), gallbladder cancer, or ampullary cancer. Bile duct cancer is further divided to intrahepatic, perihilar and distal bile duct subtypes according to the anatomical location of the tumor. The biological characteristics of ...

journal_title：Japanese journal of clinical oncology

authors： Nara S,Esaki M,Ban D,Takamoto T,Shimada K,Ioka T,Okusaka T,Ishii H,Furuse J

更新日期：2020-12-16 00:00:00

abstract：OBJECTIVE:Endobronchial ultrasound with a guide sheath has been a widely used diagnostic procedure for peripheral pulmonary lesions. After sequential sampling with the usual devices, small portions of the collected specimen remain in the guide sheath and these can potentially contribute to diagnosis. We assessed the di...

journal_title：Japanese journal of clinical oncology

authors： Izumo T,Sasada S,Chavez C,Matsumoto Y,Hayama M,Tsuchida T

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare tumor usually diagnosed at an advanced stage on invasion of or adherence to adjacent organs. We report surgical outcome of stage III and IV ACCs. METHODS:ACCs from seven patients at clinical stage II (n = 1), III (n = 4), or IV (n = 2) were resected. Combined resecti...

journal_title：Japanese journal of clinical oncology

authors： Ohwada S,Izumi M,Kawate S,Hamada K,Toya H,Togo N,Horiguchi J,Koibuchi Y,Takahashi T,Yamada M

更新日期：2007-02-01 00:00:00

abstract：:An analysis is presented of the histopathologic, clinical and prognostic features of malignant lymphomas (MLs) treated at the University of the Philippines-Philippine General Hospital Medical Center, Manila, between 1975 and 1981. There were 434 malignant lymphomas, constituting 3.86% of all cancers studied at this in...

journal_title：Japanese journal of clinical oncology

authors： Calderon B,Villalon A,Augustin B,Javier B,Zamuco J,Mori S

更新日期：1986-03-01 00:00:00

abstract：:In seeking to understand how life-threatening illness affects children psychologically, projective testing may be beneficial, particularly when attempting to identify psychological problems in younger adolescents. The advantages of projective testing are that it does not depend on patients' verbal ability and is not i...

journal_title：Japanese journal of clinical oncology

authors： Hatano Y,Yamada M,Nakagawa K,Nanri H,Kawase M,Fukui K

更新日期：2014-10-01 00:00:00