A case of amelanotic malignant melanoma of the female urethra.

abstract：:Eight cultured cell lines were established from human small cell lung cancers. Every cell line showed the morphological and biochemical characteristics of small cell cancer. Changes in cell characteristics were observed in many of these cell lines when culture conditions were changed: "oat cell type" changed to "inter...

journal_title：Japanese journal of clinical oncology

authors： Terasaki T,Shimosato Y,Nakajima T,Tsumuraya M,Morinaga S,Hirohashi S,Yamaguchi K,Kato K,Ichinose H,Nagatsu T

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVE:Although cigarette smoking is considered as an important risk factor for esophageal cancer, the magnitude of the association might be varied among geographic areas. Therefore, we reviewed epidemiologic studies on the association between cigarette smoking and esophageal cancer among the Japanese population. M...

journal_title：Japanese journal of clinical oncology

authors： Oze I,Matsuo K,Ito H,Wakai K,Nagata C,Mizoue T,Tanaka K,Tsuji I,Tamakoshi A,Sasazuki S,Inoue M,Tsugane S,Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

更新日期：2012-01-01 00:00:00

abstract：:AMG 337, a selective small-molecule MET inhibitor, was evaluated in Asian patients with advanced solid tumors. Eligible patients orally self-administered AMG 337; the initial dose of 150 mg once daily (QD) was escalated to 300 mg QD (modified 3+3+3 design). Treatment continued until disease progression, intolerability...

journal_title：Japanese journal of clinical oncology

authors： Yasui H,Go N,Yang H,Amore BM,Jung AS,Doi T

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Suboptimal treatment of chemotherapy-induced nausea and vomiting and unsatisfactory response to antiemetic drugs cause impairment of cancer patient's daily functioning. This study was aimed to investigate the association of selected germline polymorphisms with ondansetron and metoclopramide response in Indone...

journal_title：Japanese journal of clinical oncology

authors： Perwitasari DA,Wessels JA,van der Straaten RJ,Baak-Pablo RF,Mustofa M,Hakimi M,Nortier JW,Gelderblom H,Guchelaar HJ

更新日期：2011-10-01 00:00:00

abstract：Background and purpose:The objective of this study is to investigate the predictors of critical weight loss in cancer patients receiving particle therapy, and build a prediction model based on its predictive factors. Materials and methods:Patients receiving particle therapy were enroled between June 2015 and June 2016...

journal_title：Japanese journal of clinical oncology

authors： Zhang Z,Zhu Y,Zhang L,Wang Z,Wan H

更新日期：2018-01-01 00:00:00

abstract：:In the present nationwide survey, 1,040 new cases of lymphoid malignancy, in most of which expression of cell surface markers had been determined, and 243 controls for a case-control study on adult T-cell leukemia/lymphoma (ATL) and other types of lymphoid malignancies were enrolled during the two years (1982-84) from...

journal_title：Japanese journal of clinical oncology

authors：

更新日期：1985-09-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma adversely affect patients' outcomes and the quality of life; however, an adequate surveillance schedule remains unclear. METHODS:We analyzed 330 patients with early esophageal squamous cell carcinoma who un...

journal_title：Japanese journal of clinical oncology

authors： Shinozaki T,Katada C,Shiga K,Asakage T,Yokoyama T,Yano T,Oda I,Shimizu Y,Takemura K,Ishikawa H,Yokoyama A,Muto M

更新日期：2020-09-28 00:00:00

abstract：:Following a simple cholecystectomy, a 63-year-old woman with gallstones was histologically diagnosed as having minute squamous cell carcinoma of the gallbladder. A laparotomy revealed a small, firm nodule that appeared to be an adenoma, which was palpated in the fundus of the gallbladder. The resected gallbladder cont...

journal_title：Japanese journal of clinical oncology

authors： Roppongi T,Takeyoshi I,Ohwada S,Sato Y,Fujii T,Honma M,Morishita Y

更新日期：2000-01-01 00:00:00

abstract：:Squamous cell carcinoma of the head and neck is characterized by an immunosuppressive environment and evades immune responses through multiple resistance mechanisms. A breakthrough in cancer immunotherapy employing immune checkpoint inhibitors has evolved into a number of clinical trials with antibodies against progra...

journal_title：Japanese journal of clinical oncology

authors： Yokota T,Homma A,Kiyota N,Tahara M,Hanai N,Asakage T,Matsuura K,Ogawa T,Saito Y,Sano D,Kodaira T,Motegi A,Yasuda K,Takahashi S,Tanaka K,Onoe T,Okano S,Imamura Y,Ariizumi Y,Hayashi R,Japan Clinical Oncology Group (

更新日期：2020-09-28 00:00:00

abstract：:Recently total body irradiation has been used as a method of preparation for the bone marrow transplantation. However, it has become apparent that total body irradiation is one of the causes of interstitial pneumonia. There are several factors in total body irradiation that may induce interstitial pneumonia. 1) Total ...

journal_title：Japanese journal of clinical oncology

authors： Mori T,Ohizumi Y,Maezawa H,Murayama C,Tsuda M,Ando F

更新日期：1984-12-01 00:00:00

abstract：:Reduced intensity stem cell transplantation (RIST) is a new approach of stem cell transplantation, which has shown promising features as reported in multiple phase I and II studies. Elderly patients, who are not eligible for conventional myeloablative hematopoietic stem cell transplantation (HSCT), are now treatable w...

journal_title：Japanese journal of clinical oncology

authors： Kami M,Makimoto A,Heike Y,Takaue Y

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:To determine the maximum tolerated dose and recommended dose of cisplatin and docetaxel administered by three consecutive weekly infusions in both non-elderly (< or =74 years) and elderly (> or =75 years) patients, we conducted two independent phase I studies for nonelderly and elderly patients with non-smal...

journal_title：Japanese journal of clinical oncology

authors： Ohe Y,Niho S,Kakinuma R,Kubota K,Matsumoto T,Ohmatsu H,Goto K,Kunitoh H,Saijo N,Nishiwaki Y

更新日期：2001-03-01 00:00:00

abstract：:The positive correlation between smoking and cancer risk is well estimated in sporadic colorectal cancer, whereas little is known with regard to Lynch syndrome-associated colorectal cancer. A total of 118 familial colorectal cancer patients from the Hereditary Nonpolyposis Colorectal Cancer Registry and Genetic Testin...

journal_title：Japanese journal of clinical oncology

authors： Tanakaya K,Furukawa Y,Nakamura Y,Hirata K,Tomita N,Tamura K,Sugano K,Ishioka C,Yoshida T,Ishida H,Watanabe T,Sugihara K,HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum.,Yama

更新日期：2015-03-01 00:00:00

abstract：:To elucidate the relationship between the clinical features and pathologic findings of primary pulmonary lymphoma, we reviewed 24 patients with this disease. The pulmonary lymphomas were divided into four groups: (1) B-cell lymphoma composed of small to medium-sized lymphoid cells (19 cases); (2) B-cell lymphoma compo...

journal_title：Japanese journal of clinical oncology

authors： Tamura A,Komatsu H,Yanai N,Homma J,Nagase A,Nemoto E,Hirai T,Hashizume T,Kawata K,Ishikawa S

更新日期：1995-08-01 00:00:00

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess clinically the adequacy of vessel-contouring-based pelvic radiotherapy with regard to nodal coverage for uterine cervical cancer. METHODS:Fifty patients with Stages I-III cervical cancer, treated with vessel-contouring-based three-dimensional radiotherapy since August 2002...

journal_title：Japanese journal of clinical oncology

authors： Uno T,Isobe K,Ueno N,Kobayashi H,Sanayama Y,Mitsuhashi A,Shozu M,Ito H

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to find the frequency and the role of epidermal growth factor receptor expression as a prognostic biomarker in gastric cancer. METHODS:We evaluated the prognostic value and frequency of epidermal growth factor receptor expression and amplification using immunohistochemistry and silve...

journal_title：Japanese journal of clinical oncology

authors： Park JS,Kim HS,Bae YS,Cheong JH,Rha SY,Noh SH,Kim H

更新日期：2016-06-01 00:00:00

abstract：:We report a rare case of Bellini duct carcinoma, which is an unusual variant of renal cell carcinoma. The patient, a 56-year-old man, was admitted to our hospital for detailed examination of a renal mass on the left side. He had no clinical symptoms such as gross hematuria or flank pain. Abdominal ultrasonography, com...

journal_title：Japanese journal of clinical oncology

authors： Natsume O,Ozono S,Futami T,Ohta M

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:The prognosis of breast cancer-derived brain metastasis is poor, but new drugs and recent therapeutic strategies have helped extend survival in patients. Prediction of therapeutic responses and outcomes is not yet possible, however. In a retrospective study, we examined prognostic factors in patients with bre...

journal_title：Japanese journal of clinical oncology

authors： Honda Y,Aruga T,Yamashita T,Miyamoto H,Horiguchi K,Kitagawa D,Idera N,Goto R,Kuroi K

更新日期：2015-08-01 00:00:00

abstract：:Uterine inversion caused by uterine sarcoma is a rare condition with 12 reported cases to date according to a MEDLINE search. We report two cases of this rare condition. A 71- and a 72-year-old woman presented with uterine sarcomas rapidly extruded into the vagina. In both cases, magnetic resonance imaging (MRI) scans...

journal_title：Japanese journal of clinical oncology

authors： Takano K,Ichikawa Y,Tsunoda H,Nishida M

更新日期：2001-01-01 00:00:00

abstract：:The relations between alcohol consumption and cancers of the breast, corpus uteri and ovary were investigated in a case-control study involving 1,740 cases of breast cancer, 239 cases of cancer of the corpus uteri, 417 cases of ovarian cancer and 8,920 controls with other cancer sites identified from the Aichi Cancer ...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Tominaga S,Terao C

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:We evaluated the feasibility of combination chemotherapy with paclitaxel, doxorubicin and cisplatin without prophylactic granulocyte colony-stimulating factor injection for intermediate-to-high-risk or recurrent endometrial cancer. METHODS:Women with histologically confirmed FIGO Stages I-II with >1/2 myomet...

journal_title：Japanese journal of clinical oncology

authors： Nagao S,Nishikawa T,Hanaoka T,Kurosaki A,Iwasa N,Hasegawa K,Fujiwara K

更新日期：2014-11-01 00:00:00

abstract：Purpose:To investigate the usefulness of screening for patient symptoms as the fifth vital sign using an electronic medical recording system. Patients and methods:In the electronic medical recording system, all admitted patients received routine nurse-based assessment of discomfort (defined as any physical symptom) at...

journal_title：Japanese journal of clinical oncology

authors： Naito AS,Sakuma Y,Kinoshita H,Ito T,Mimatsu S,Tarumi A,Kiyohara E,Morita T

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Although adjuvant analgesics are used to treat opioid-refractory cancer pain, there is insufficient evidence to support this practice and limited data to guide the choice depending on cancer pain pathophysiology, dose titration and starting dose. This survey aimed to clarify the current use of adjuvant analg...

journal_title：Japanese journal of clinical oncology

authors： Tagami K,Matsuoka H,Ariyoshi K,Oyamada S,Hiratsuka Y,Kizawa Y,Koyama A,Inoue A

更新日期：2020-12-16 00:00:00

abstract：:A case of ovarian cystadenocarcinoma associated with pregnancy is reported. The semicystic left ovarian tumor was found in a 28-year-old woman, gravida 2, para 1 at 33 weeks' gestation. A primary Cesarean section, total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by chemotherapy were performed....

journal_title：Japanese journal of clinical oncology

authors： Sawada M,Yamasaki M,Urabe T,Katayama S,Yamane T

更新日期：1990-06-01 00:00:00

abstract：:Of the patients with colorectal cancer, there are some with hereditary disorders such as familial polyposis coli, Gardner's syndrome, Turcot's syndrome, and cancer family syndrome in which colorectal adenocarcinoma develops at a significantly high frequency, and these hereditary diseases are very important and interes...

journal_title：Japanese journal of clinical oncology

authors： Ushio K

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:To describe computed tomographic (CT) features of highly enhanced hepatic masses as seen on CT during arterial portography (CTAP) and to survey the varieties of hepatic lesions associated with such findings. METHODS:CTAP files for 400 patients were reviewed, on the basis of which six patients with highly en...

journal_title：Japanese journal of clinical oncology

authors： Onaya H,Itai Y,Satake M,Luo T,Saida Y,Haruno M,Hasebe T,Moriyama N

更新日期：2000-10-01 00:00:00

abstract：:The hematogenous metastases of colon cancer have primarily been explained by the cascade hypothesis based on the cadaveric study. However, we experienced several cases with isolated lung metastasis. The metastatic patterns of a total of 982 patients with colon cancer who underwent surgery were reviewed. The incidence ...

journal_title：Japanese journal of clinical oncology

authors： Sadahiro S,Suzuki T,Tanaka A,Okada K,Kamata H

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:One of the most studied pro-angiogenic factors involved in the development of colorectal cancer is the vascular endothelial growth factor (VEGF). The small molecule tyrosine kinase inhibitor semaxanib (SU5416) is one of the several agents targeting the VEGF signaling pathway, and its development centered mos...

journal_title：Japanese journal of clinical oncology

authors： Hoff PM,Wolff RA,Bogaard K,Waldrum S,Abbruzzese JL

更新日期：2006-02-01 00:00:00